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Physical Activity and Hematologic Cancer Prevention

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Physical Activity and Cancer

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 186))

Abstract

This chapter presents the epidemiologic evidence on the association between physical activity and hematologic cancers and related hypothesized biologic mechanisms. Some preliminary indications of a protective role for physical activity for non-Hodgkin’s lymphoma, leukemia, multiple myeloma, and Hodgkin’s lymphoma exist, but the level of epidemiologic evidence is still insufficient to make any definitive conclusions regarding the nature of these associations. Several plausible biologic mechanisms underlying the possible associations between physical activity and hematologic cancers have been proposed, including enhancement of immune function, reduction in obesity, improvement of antioxidant defense systems, impact on metabolic hormones, and anti-inflammatory effects. Future studies should improve the estimation of physical activity by using more reliable, valid, and comprehensive measurement tools, assessing all components of physical activity (type, intensity, and time period), and conducting intervention studies to evaluate the effect of physical activity on various biomarkers of cancer in order to provide further insight into plausible biologic mechanisms underlying the possible association between physical activity and hematologic cancers.

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  1. Centre for Chronic Disease Prevention and Control, Public Health Agency of Canada, 785 Carling Avenue, Locator: 6807B, Ottawa, Ontario, K1A 0K9, Canada

    Sai Yi Pan & Howard Morrison

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  1. Sai Yi Pan
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  1. Fac. Physical Education & Recreation, University of Alberta, Van Vliet Center E488, Edmonton, T6G 2H9, Alberta, Canada

    Kerry S. Courneya

  2. Div. Population Health & Information, Tom Baker Cancer Centre, 29th Street NW., 1331, Calgary, T2N 4N2, Alberta, Canada

    Christine M. Friedenreich

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Pan, S.Y., Morrison, H. (2010). Physical Activity and Hematologic Cancer Prevention. In: Courneya, K., Friedenreich, C. (eds) Physical Activity and Cancer. Recent Results in Cancer Research, vol 186. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-04231-7_6

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