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Mapping the Brain for Primary Brain Tumor Surgery

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Malignant Brain Tumors

Abstract

Extensive resective surgery plays a major role in prolonging survival of glioma patients. However, patient’s will is not to survive as long as possible, but rather to enjoy the longest possible «normal» life. Because glioma infiltrates functional tissue, it is necessary to define resection boundaries by functional maps rather than by tumoral imaging. In this perspective, advances in brain mapping have deeply improved the surgical management of glioma patients. In this chapter, we summarize the preoperative and intraoperative methods that allows to map the brain and we review the cortical and axonal mapping of the main cognitive functions.

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Abbreviations

ACEPS:

Axonal-cortical evoked potentials

CCEPs:

Cortico-cortical evoked potentials

CST:

Cortico-spinal tract

DES:

Direct electrical stimulation

DTI:

Diffusion tensor imaging

ECoG:

Electrocortiograms

HGA:

High-gamma activity

IFOF:

Inferior fronto-occipital fasciculus

PPTT:

Pyramid-palm-tree test

R-fMRI :

Rest-based fMRI

rTMS:

Repetitive transcranial magnetic stimulation

SLF:

Superior longitudinal fasciculus

SMA:

Supplementary motor area

T-fMRI:

Task-based fMRI

vPMC:

Ventral premotor cortex

VWFA:

Visual word from area

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Authors and Affiliations

  1. Department of Neurosurgery, Lariboisière Hospital, Paris, France

    Emmanuel Mandonnet

  2. Department of Neurosurgery, Gui de Chauliac Hospital, Montpellier, France

    Hugues Duffau

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  1. Emmanuel Mandonnet
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  2. Hugues Duffau
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Correspondence to Hugues Duffau .

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Editors and Affiliations

  1. Neurosurgical Oncology, Yale University School of Medicine Neurosurgical Oncology, New Haven, Connecticut, USA

    Jennifer Moliterno Gunel

  2. Yale University School of Medicine, New Haven, Connecticut, USA

    Joseph M Piepmeier

  3. Yale School of Medicine, New Haven, Connecticut, USA

    Joachim M. Baehring

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Mandonnet, E., Duffau, H. (2017). Mapping the Brain for Primary Brain Tumor Surgery. In: Moliterno Gunel, J., Piepmeier, J., Baehring, J. (eds) Malignant Brain Tumors . Springer, Cham. https://doi.org/10.1007/978-3-319-49864-5_5

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