Abstract
Periprosthetic knee infection is a severe and not infrequent complication, with an incidence ranging from 0.4 to 2.5% for primary TKA and 4 to 8% for revision surgery. For acute infection, prosthesis removal is not necessary and a simple DAIR should be performed in association with replacement of the polyethylene insert. For subacute or chronic infection, prosthetic replacement is necessary, and two methods of management can be discussed: single-stage or two-stage exchange arthroplasty. Although single-stage exchange knee arthroplasty is possible in certain specific cases, prosthetic replacement in two stages is currently considered as standard treatment. During two-stage exchange arthroplasty, the first stage is to remove all prosthetic material with thorough debridement of the periprosthetic tissues. Multiple tissue samples are collected during the first stage debridement. An antibiotic-impregnated cement spacer is positioned in place of the TKA implants. Later, once the infection is controlled, prosthesis reimplantation is performed during the second stage. The optimal delay before the second surgery is still debated. The use of a cement spacer is practically systematic in the treatment of TKA infection, because it allows the preservation of sufficient joint space during the intermediate period without a prosthesis, which allows maintenance of the space for reimplantation of the new prosthesis during the second stage surgery. There are two types of spacer commonly used: static spacer or dynamic spacer. Both types of spacer have advantages and disadvantages.
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Acknowledgments
Lyon bone and joint study group (list of collaborators)
Coordinator: Tristan Ferry; Infectious diseases specialists: Tristan Ferry, Florent Valour, Thomas Perpoint, Patrick Miailhes, Florence Ader, Sandrine Roux, Agathe Becker, Claire Triffault-Fillit, Anne Conrad, Cécile Pouderoux, Nicolas Benech, Pierre Chauvelot, Marielle Perry, Fatiha Daoud, Johanna Lippman, Evelyne Braun, Christian Chidiac; Surgeons: Elvire Servien, Cécile Batailler, Stanislas Gunst, Axel Schmidt, Matthieu Malatray, Eliott Sappey-Marinier, Michel-Henry Fessy, Anthony Viste, Jean-Luc Besse, Philippe Chaudier, Lucie Louboutin, Quentin Ode, Adrien Van Haecke, Marcelle Mercier, Vincent Belgaid, Arnaud Walch, Sébastien Martres, Franck Trouillet, Cédric Barrey, Ali Mojallal, Sophie Brosset, Camille Hanriat, Hélène Person, Nicolas Sigaux, Philippe Céruse, Carine Fuchsmann; Anesthesiologists: Frédéric Aubrun, Mikhail Dziadzko, Caroline Macabéo; Microbiologists: Frédéric Laurent, Laetitia Beraud, Tiphaine Roussel-Gaillard, Céline Dupieux, Camille Kolenda, Jérôme Josse; Pathology: Marie Brevet, Alexis Trecourt; Imaging: Fabien Craighero, Loic Boussel, Jean-Baptiste Pialat, Isabelle Morelec; PK/PD specialists: Michel Tod, Marie-Claude Gagnieu, Sylvain Goutelle; Clinical research assistant and database manager: Eugénie Mabrut.
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Barnavon, T. et al. (2022). The Use of Static Spacers in Periprosthetic Knee Infections. In: Longo, U.G., Budhiparama, N.C., Lustig, S., Becker, R., Espregueira-Mendes, J. (eds) Infection in Knee Replacement. Springer, Cham. https://doi.org/10.1007/978-3-030-81553-0_18
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DOI: https://doi.org/10.1007/978-3-030-81553-0_18
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