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CT-Determined Body Composition Changes with Recombinant Human Growth Hormone Treatment to Adults with Growth Hormone Deficiency

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Human Body Composition

Part of the book series: Basic Life Sciences ((BLSC,volume 60))

Abstract

Growth hormone (GH) is secreted in children as well as in adults. Several studies show an important role of GH in adults. Recent trials with recombinant human growth hormone (rhGH) have demonstrated profound effects on body composition, metabolism and quality of life.1,2 Salomon et al1 showed that adults with growth hormone deficiency had decreased lean body mass and increased body fat. Treatment with rhGH for six months increased lean body mass (LBM) and reduced body fat. Jörgensen et al2 have shown that four months of GH substitution to GH-deficient adults had a normalizing effect on several physiological variables, which were out of normal range before treatment.

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References

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© 1993 Springer Science+Business Media New York

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Lönn, L., Kvist, H., Grangård, U., Bengtsson, BÅ., Sjöström, L. (1993). CT-Determined Body Composition Changes with Recombinant Human Growth Hormone Treatment to Adults with Growth Hormone Deficiency. In: Ellis, K.J., Eastman, J.D. (eds) Human Body Composition. Basic Life Sciences, vol 60. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1268-8_53

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  • DOI: https://doi.org/10.1007/978-1-4899-1268-8_53

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1270-1

  • Online ISBN: 978-1-4899-1268-8

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