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The insulin-like growth factors, their receptors, and their binding proteins in human breast cancer

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Regulatory Mechanisms in Breast Cancer

Part of the book series: Cancer Treatment and Research ((CTAR,volume 53))

Abstract

The ability to grow breast cancer cells in vitro has lead to the identification of several polypeptide hormones that may regulate their growth. The insulin- like growth factors (IGFs) have been identified as potent mitogens for breast cancer cells in vitro and increasing evidence has suggested that the IGFs may have an important function in the proliferation of mammary epithelia. This chapter will examine the data that support a role for the IGFs in regulating the growth of breast cancer cells.

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Authors
  1. Douglas Yee
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  2. Neal Rosen
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  3. Roberto E. Favoni
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  4. Kevin J. Cullen
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Editors and Affiliations

  1. Lombardi Cancer Research Center, USA

    Marc E. Lippman  & Robert B. Dickson  & 

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© 1991 Springer Science+Business Media New York

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Yee, D., Rosen, N., Favoni, R.E., Cullen, K.J. (1991). The insulin-like growth factors, their receptors, and their binding proteins in human breast cancer. In: Lippman, M.E., Dickson, R.B. (eds) Regulatory Mechanisms in Breast Cancer. Cancer Treatment and Research, vol 53. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3940-7_5

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  • DOI: https://doi.org/10.1007/978-1-4615-3940-7_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6758-1

  • Online ISBN: 978-1-4615-3940-7

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