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Epstein-Barr Virus

  • Chapter
Viral Infections of Humans

Abstract

Epstein-Barr virus (EBV), a member of the herpes group of viruses, is the cause of heterophil-positive infectious mononucleosis, of most heterophil-negative cases, and of occasional cases of tonsillitis and pharyngitis in childhood. Rarely, it may involve the liver or central nervous system as primary manifestations. This virus is also implicated as having a causal relationship to African Burkitt lymphoma and to nasopharyngeal cancer. High antibody titers are present in 30–40% of cases of Hodgkin disease, in some patients with sarcoidosis, and in systemic lupus erythematosus.

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  1. WHO Serum Reference Bank, Section of International Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, 06510, USA

    Alfred S. Evans

  2. Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, 06510, USA

    James C. Niederman

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  1. Alfred S. Evans
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  1. Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USA

    Alfred S. Evans

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Evans, A.S., Niederman, J.C. (1989). Epstein-Barr Virus. In: Evans, A.S. (eds) Viral Infections of Humans. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0705-1_10

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