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Neurobiology of Stress-Induced Tinnitus

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The Behavioral Neuroscience of Tinnitus

Part of the book series: Current Topics in Behavioral Neurosciences ((CTBN,volume 51))

Abstract

Emotional stress has accompanied humans since the dawn of time and has played an essential role not only in positive selection and adaptation to an ever-changing environment, but also in the acceleration or even initiation of many illnesses. The three main somatic mechanisms induced by stress are the hypothalamus-pituitary-adrenal axis (HPA axis), the sympathetic-adreno-medullar (SAM) axis, and the immune axis. In this chapter, the stress-induced mechanisms that can affect cochlear physiology are presented and discussed in the context of tinnitus generation and auditory neurobiology. It is concluded that all of the presented mechanisms need to be further investigated. It is advised that clinical practitioners ask patients about stressful events or chronic stress preceding the tinnitus onset and measure the vital signs. Finally, taking into account that tinnitus itself acts as a stressor, the implementation of anti-stress therapies for tinnitus treatment is recommended.

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Authors and Affiliations

  1. Department of Otorhinolaryngology, Head and Neck Surgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

    Agnieszka J. Szczepek

  2. Faculty of Medicine and Health Sciences, University of Zielona Góra, Zielona Góra, Poland

    Agnieszka J. Szczepek

  3. Tinnitus Center, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

    Birgit Mazurek

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  1. Agnieszka J. Szczepek
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  2. Birgit Mazurek
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Correspondence to Agnieszka J. Szczepek .

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Editors and Affiliations

  1. Medical and Health Sciences, University of Auckland, Auckland, New Zealand

    Grant D. Searchfield

  2. Department of Communication Sciences and Disorders, Department of Otolaryngology-Head Neck and Surgery, Wayne State University, Detroit, MI, USA

    Jinsheng Zhang

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Szczepek, A.J., Mazurek, B. (2021). Neurobiology of Stress-Induced Tinnitus. In: Searchfield, G.D., Zhang, J. (eds) The Behavioral Neuroscience of Tinnitus. Current Topics in Behavioral Neurosciences, vol 51. Springer, Cham. https://doi.org/10.1007/7854_2020_215

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