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Splanchnic Perfusion and Oxygenation in Critical Illness

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Yearbook of Intensive Care and Emergency Medicine

Part of the book series: Yearbook of Intensive Care and Emergency Medicine ((YEARBOOK,volume 2006))

Conclusion

Since splanchnic impairment of perfusion and oxygenation triggers and perpetuates critical illness, including sepsis and MOF, it is crucial to elucidate the splanchnic effects of common clinical interventions applied in intensive care medicine. Herein, findings of experimental studies may serve to reduce the complexity of splanchnic pathophysiology and generate promising concepts to be tested in the clinical setting. Maybe we have to become familiar with the thought that there is not a single variable guiding our therapy of splanchnic hypoperfusion. Just as we have learned not to judge systemic hemodynamics by a single variable, future splanchnic monitoring tools will enable us to extend our ability to recognize patterns indicative of splanchnic hypoperfusion. Despite major advances in splanchnic monitoring techniques, a combination of easy-to-use and minimally-invasive metabolic and perfusion measurements allowing us to recognize pathophysiologic patterns in splanchnic perfusion and metabolism is not in sight. Ultimately, this concept should enable us to base our therapy on systemic and splanchnic circulatory variables to improve outcomes for the critically ill.

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Author information

Authors and Affiliations

  1. Department of Physiology Academic Medical Center, University of Amsterdam, Meibergdreef 19, 1105 AZ, Amsterdam, The Netherlands

    L. A. Schwarte & C. Ince

  2. Department of Anesthesiology, University Hospital, Moorenstraße 5, 40225, Düsseldorf, Germany

    M. F. Stevens

Authors
  1. L. A. Schwarte
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  2. M. F. Stevens
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  3. C. Ince
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Editors and Affiliations

  1. Department of Intensive Care, Erasme Hospital, Free University of Brussels, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean-Louis Vincent (Head) (Head)

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© 2006 Springer-Verlag Berlin Heidelberg

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Schwarte, L.A., Stevens, M.F., Ince, C. (2006). Splanchnic Perfusion and Oxygenation in Critical Illness. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine. Yearbook of Intensive Care and Emergency Medicine, vol 2006. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-33396-7_58

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  • DOI: https://doi.org/10.1007/3-540-33396-7_58

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-30155-4

  • Online ISBN: 978-3-540-33396-8

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