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A Wide Gap Second Derivative NIR Spectroscopic Method for Measuring Tissue Hemoglobin Oxygen Saturation

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Oxygen Transport to Tissue XXVII

4. Conclusions

We describe a four wavelength continuous wave near-infrared algorithm for estimating hemoglobin oxygen saturation in tissue using single depth attenuation measurements. The 40 nm gap second derivative algorithm and in vitro calibration method provided StO2 measurements of reasonable accuracy that were applied across a variety of tissues and probe spacings with no measured or assumed values for optical pathlength or optical scattering.

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Myers, D.E. et al. (2006). A Wide Gap Second Derivative NIR Spectroscopic Method for Measuring Tissue Hemoglobin Oxygen Saturation. In: Cicco, G., Bruley, D.F., Ferrari, M., Harrison, D.K. (eds) Oxygen Transport to Tissue XXVII. Advances in Experimental Medicine and Biology, vol 578. Springer, Boston, MA . https://doi.org/10.1007/0-387-29540-2_35

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