4. Conclusions
We describe a four wavelength continuous wave near-infrared algorithm for estimating hemoglobin oxygen saturation in tissue using single depth attenuation measurements. The 40 nm gap second derivative algorithm and in vitro calibration method provided StO2 measurements of reasonable accuracy that were applied across a variety of tissues and probe spacings with no measured or assumed values for optical pathlength or optical scattering.
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8. References
S. J. Matcher and C. E. Cooper, Absolute quantification of deoxyhemoglobin concentration in tissue near infrared spectroscopy, Phys Med Biol 39, 1295–1312 (1994).
C. E. Cooper, C. E. Elwell, J. H. Meek, S. J. Matcher, J. S. Wyatt, M. Cope, and D. T. Delpy, The noninvasive measurement of absolute cerebral deoxyhemoglobin concentration and mean optical path length in the neonatal brain by second derivative near infrared spectroscopy, Pediatr Res 39, 32–8 (1996).
K. A. Schenkman, D. R. Marble, D. H. Burns, and E. O Feigl, Optical spectroscopic method for in vivo measurement of cardiac myoglobin oxygen saturation, Applied Spectroscopy 53(3), 332–338 (1999).
T. Binzoni, T. Leung, V. Hollis, S. Bianchi, J. H. Fasel, H. Bounameaux, E. Hiltbrand, and D. Delpy, Human tibia bone marrow: defining a model for the study of haemodynamics as a function of age by near infrared spectroscopy, J Physiol Anthropol Appl Human Sci 22, 211–218 (2003).
S. J. Matcher, C. E. Elwell, C. E. Cooper, M. Cope, and D. T. Delpy, Performance comparison of several published tissue near-infrared spectroscopy algorithms, Anal Biochem 227, 54–68 (1995).
S. R. Arridge, M. Cope, and D. T. Delpy, The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis, Phys Med Biol 37(7), 1531–1560 (1992).
S. J. Matcher, P. Kirkpatrick, K. Nahid, M. Cope, and D. T. Delpy, Absolute quantification methods in tissue near infrared spectroscopy, Proc SPIE 2389, 486–495 (1995).
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Myers, D.E. et al. (2006). A Wide Gap Second Derivative NIR Spectroscopic Method for Measuring Tissue Hemoglobin Oxygen Saturation. In: Cicco, G., Bruley, D.F., Ferrari, M., Harrison, D.K. (eds) Oxygen Transport to Tissue XXVII. Advances in Experimental Medicine and Biology, vol 578. Springer, Boston, MA . https://doi.org/10.1007/0-387-29540-2_35
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