This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

The aim of the review is to assess the effectiveness of non hormonal therapies for improving hot flushes in patients with breast cancer.

Primary Objective:
To examine the effectiveness of non‐hormonal treatments for relieving hot flushes in women with breast cancer compared to placebo or no treatment group.

Secondary Objectives:
To determine adverse effects of non‐hormonal treatments
To evaluate the impact on quality of life of non‐hormonal treatments versus control or placebo.