Abstract
Up to now studies on porphyrin biosynthesis in human skin are scarce (Bickers et al, 1977; Goerz et al, 1995; Navone et al, 1988). Examinations were predominantly done to study the pathomechanism of porphyria diseases, but recently porphyrin studies have been increasingly used to measure the effect of PDT with ALA-induced porphyrins. The main questions are, why tumor cells display increased uptake of ALA and why tumors predominantly transform ALA into porphyrins, accumulate them and do not metabolize porphyrins to heme.
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© 2003 Springer-Verlag/Wien
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Fritsch, C., Ruzicka, T. (2003). In vivo — Investigations on ALA-induced Porphyrins/FDAP. In: Fluorescence Diagnosis and Photodynamic Therapy of Skin Diseases. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6046-6_7
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DOI: https://doi.org/10.1007/978-3-7091-6046-6_7
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-83827-3
Online ISBN: 978-3-7091-6046-6
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