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Blood-Optic Nerve Barrier

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Ischemic Optic Neuropathies

Abstract

The blood-optic nerve barrier is an important subject in any consideration of optic nerve and optic nerve head (ONH) vascular disorders. The capillaries in the ONH and the rest of the optic nerve, as in the retina [1–5] and in the central nervous system [6–10] have tight cell junctions between adjacent endothelial cells, without fenestration [11–13]. These tight junctions are responsible for the blood-optic nerve barrier, which has been shown by intravenous injection of tracer substances, such as horseradish peroxidase [14–16] and diaminoacridines [17].

For a complete bibliography and detailed review of previously published studies in the literature on the subject, please refer to bibliography in previous publications listed here.

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  1. Department of Ophthalmology and Visual Science, University of Iowa Hospital and Clinics College of Medicine, Hawkins Dr. 200, Iowa City, IA, 52242–1091, USA

    Dr. Sohan Singh Hayreh

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Hayreh, S.S. (2011). Blood-Optic Nerve Barrier. In: Ischemic Optic Neuropathies. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11852-4_4

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  • DOI: https://doi.org/10.1007/978-3-642-11852-4_4

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