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Sepsis and the Lung

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Sepsis

Part of the book series: Respiratory Medicine ((RM))

Abstract

Infections of the lung and pleural space are frequently associated with the development of sepsis syndromes. Additionally, sepsis from any source, pulmonary or extrapulmonary, may result in additional injury to the lung, known as the acute respiratory distress syndrome (ARDS), a syndrome characterized by an over-exuberant inflammatory response in the lung leading to increased alveolar-capillary permeability and predominantly non-hydrostatic pulmonary edema and hypoxemia. This syndrome and its complications contribute heavily to the morbidity and mortality associated with sepsis, and although no specific therapy exists to treat ARDS, supportive therapy including the use of low tidal volume ventilation can significantly improve outcomes.

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Authors and Affiliations

  1. Division of Pulmonary and Critical Care Medicine, University of Vermont College of Medicine, 89 Beaumont Avenue, Given E407, Burlington, VT, 05405, USA

    MaryEllen Antkowiak MD, Lucas Mikulic MD & Benjamin T. Suratt MD

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  1. MaryEllen Antkowiak MD
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  2. Lucas Mikulic MD
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  3. Benjamin T. Suratt MD
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Correspondence to Benjamin T. Suratt MD .

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Editors and Affiliations

  1. Division of Pulmonary Critical Care, and Sleep Medicine, Alpert/Brown Medical School, Providence, Rhode Island, USA

    Nicholas S. Ward

  2. Division of Pulmonary Critical Care, and Sleep Medicine, Alpert/Brown Medical School, Providence, Rhode Island, USA

    Mitchell M. Levy

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Antkowiak, M., Mikulic, L., Suratt, B.T. (2017). Sepsis and the Lung. In: Ward, N., Levy, M. (eds) Sepsis. Respiratory Medicine. Humana Press, Cham. https://doi.org/10.1007/978-3-319-48470-9_9

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  • DOI: https://doi.org/10.1007/978-3-319-48470-9_9

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