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Life Histories: Real and Synthetic

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Multistate Analysis of Life Histories with R

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Abstract

Life history data are generally incomplete. Usually, they do not cover for each individual in the study the entire life span or the life segment of interest. If data are collected retrospectively, observation ends at interview date, and no information is available on events and experiences after the date. Data collected prospectively are incomplete because events and other experiences are recorded during a limited period of time only. To deal with data limitations, models are introduced. The model that is considered in this chapter describes life histories. The model is based on the premise that life histories are realisations of a continuous-time Markov process. A Markov process is a stochastic process that describes a system with multiple states and transitions between the states. The time at which a transition occurs is random but the distribution of the time to transition is known. In the continuous-time Markov process, the transition time has an exponential distribution. The rate of transition out of the current state (exit rate) is the parameter of the exponential distribution. It depends on the current state only and is independent of the history of the stochastic process. In a system with multiple states, an individual who leaves the current state may enter one of several states. In competing risks models, states in the state space are viewed as competing destinations and transition rates are destination-specific. The Markov process is a first-order process: the destination state depends on the current state only and is independent of states occupied previously.

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Notes

  1. 1.

    Prediction is used in the statistical meaning. Prediction is a statement about an outcome. A model is often used to predict an outcome, e.g. an event that occurs in a population or that is experienced by an individual in a population. The parameter(s) of the model are estimated from observations on a selection of individuals. Prediction is part of statistical inference. It should not be confused with forecasting.

  2. 2.

    http://www.statcan.gc.ca/microsimulation/lifepaths/lifepaths-eng.htm

References

  • Aalen, O. O., Borgan, Ø., & Gjessing, H. K. (2008). Survival and event history analysis. A process point of view. New York: Springer.

    Book  MATH  Google Scholar 

  • Allignol, A. (2013). Package mvna. Nelson-Aalen estimator of the cumulative hazard in multistate models. Published on CRAN.

    Google Scholar 

  • Allignol, A., Beyersmann, J., & Schumacher, M. (2008). mvna: An R package for the Nelson-Aalen estimator in multistate models. R Newsletter, 8(2), 48–50.

    Google Scholar 

  • Allignol, A., Schumacher, M., & Beyersmann, J. (2011). Empirical transition matrix of multistate models: The etm package. Journal of Statistical Software, 38(4), 15.

    Google Scholar 

  • Andersen, P. K., & Keiding, N. (2002). Multi-state models for event history analysis. Statistical Methods in Medical Research, 11, 91–115.

    Article  MATH  Google Scholar 

  • Aoki, M. (1996). New approaches to macroeconomic modeling. Evolutionary stochastic dynamics, multiple equilibria, and externalities as field effects. Cambridge: Cambridge University Press.

    Book  Google Scholar 

  • Beyersmann, J., & Putter, H. (2014). A brief note on computing average state occupation times. Demographic Research, Forthcoming.

    Google Scholar 

  • Beyersmann, J., Schumacher, M., & Allignol, A. (2012). Competing risks and multistate models with R. New York: Springer.

    Book  MATH  Google Scholar 

  • Blossfeld, H. P., & Rohwer, G. (2002). Techniques of event history modeling. New approaches to causal analysis (2nd ed.). Mahwah: Lawrence Erlbaum Associates.

    MATH  Google Scholar 

  • Chiang, C. L. (1968). Introduction to stochastic processes in biostatistics. New York: Wiley. Chapter 9 reprinted in Bogue, D. J., Arriage, E. E., & Anderton, E. L. (Eds.). (1993). Readings in population research methodology (Vol. 2, pp. 7.84–7.97). Chicago/New York: Social Development Center/UNFPA.

    Google Scholar 

  • Chiang, C. L. (1984). The life table and its applications. Malabar: R.E. Krieger Publishing.

    Google Scholar 

  • Çinlar, E. (1975). Introduction to stochastic processes. Englewood Cliffs: Prentice-Hall.

    MATH  Google Scholar 

  • de Wreede, L. C., Fiocco, M., & Putter, H. (2010). The mstate package for estimation and prediction in non- and semi-parametric multi-state and competing risks models. Computer Methods and Programs in Biomedicine, 99, 261–274. doi:10.1016/j.cmpb.2010.01.001.

    Article  Google Scholar 

  • de Wreede, L. C., Fiocco, M., & Putter, H. (2011). mstate: An R package for the analysis of competing risks and multistate models. Journal of Statistical Software, 38(7), 1–30.

    Google Scholar 

  • Helbing, D. (2010). Quantitative sociodynamics. Stochastic methods and models of social interaction processes. Berlin: Springer.

    MATH  Google Scholar 

  • Hoem, J. M., & Funck Jensen, U. (1982). Multistate life table methodology: A probabilist critique. In K. C. Land & A. Rogers (Eds.), Multidimensional mathematical demography (pp. 155–264). New York: Academic.

    Chapter  Google Scholar 

  • Holford, T. R. (1980). The analysis of rates and of survivorship using log-linear models. Biometrics, 36, 299–305.

    Article  MATH  Google Scholar 

  • Hougaard, P. (2000). Analysis of multistate survival data. New York: Springer.

    Book  Google Scholar 

  • Izmirlian, G., Brock, D., Ferrucci, L., & Phillips, C. (2000). Active life expectancy from annual follow-up data with missing responses. Biometrics, 56(1), 244–248.

    Article  MATH  Google Scholar 

  • Jackson, C. (2011). Multi-state models for panel data: The msm package for R. Journal of Statistical Software, 38(8), 28.

    Google Scholar 

  • Korn, E. I., Graubard, B. I., & Midthune, D. (1997). Time-to-event analysis of longitudinal follow-up of a survey: Choice of time-scale. American Journal of Epidemiology, 145(1), 72–80.

    Article  Google Scholar 

  • Laird, N., & Olivier, D. (1981). Covariance analysis of censored survival data using log-linear analysis techniques. Journal of the American Statistical Association, 76(374), 231–240.

    Article  MathSciNet  MATH  Google Scholar 

  • Li, Y., Gail, M. H., Preston, D. L., Graubard, B. I., & Lubin, J. H. (2012). Piecewise exponential survival times and analysis of case-control data. Statistics in Medicine, 31(13), 1361–1368.

    Article  MathSciNet  Google Scholar 

  • Mamun, A. A. (2003). Life history of cardiovascular disease and its risk factors. Amsterdam: Rozenberg Publishers.

    Google Scholar 

  • Meira-Machado, L. M., et al. (2009). Multi-state models for the analysis of time-to-event data. Statistical Methods in Medical Research, 18(2), 195–222.

    Article  MathSciNet  Google Scholar 

  • Namboodiri, K., & Suchindran, C. M. (1987). Life table techniques and their applications. Orlando: Academic.

    Google Scholar 

  • Pencina, M. J., Larson, M. G., & D’Agostino, R. B. (2007). Choice of time scale and its effect on significance of predictors in longitudinal studies. Statistics in Medicine, 26, 1343–1359.

    Article  MathSciNet  Google Scholar 

  • Putter, H. (2011a). Special issue about competing risks and multi-state models. Journal of Statistical Software, 38(1), 1–4.

    MathSciNet  Google Scholar 

  • Putter, H. (2011b). Package dynpred. Companion package to “Dynamic prediction in clinical survival analysis”. Chapman and Hall/CRC Publishers. Published on CRAN.

    Google Scholar 

  • Reuser, M. (2010). The effect of risk factors on compression or expansion of disability a multistate analysis of the U.S. health and retirement study. Amsterdam: Rozenberg Publishers.

    Google Scholar 

  • Rogers, A. (1975). Introduction to multiregional mathematical demography. New York: Wiley.

    Google Scholar 

  • Rogers, A. (1986). Parameterized multistate population dynamics and projections. Journal of the American Statistical Association, 81(393), 48–61.

    Article  Google Scholar 

  • Schoen, R. (1988). Modeling multigroup populations. New York: Plenum Press.

    Book  Google Scholar 

  • Tuma, N. B., & Hannan, M. T. (1984). Social dynamics. Models and methods. Orlando: Academic.

    Google Scholar 

  • Van den Hout, A. (2013). ELECT: Estimation of life expectancies using continuous-time multi-state survival models. Available at http://www.ucl.ac.uk/~ucakadl/ELECT_Manual_13_02_2013.pdf. Accessed 4 May 2014.

  • Van den Hout, A., & Matthews, E. F. (2008). Multi-state analysis of cognitive ability data: A piecewise-constant model and a Weibull model. Statistics in Medicine, 27, 5440–5455.

    Article  MathSciNet  Google Scholar 

  • Van den Hout, A., Ogurtsova, E., Gampe, J., & Matthews, F. E. (2014). Investigating healthy life expectancy using a multi-state model in the presence of missing data and misclassification. Demographic Research. In print.

    Google Scholar 

  • Van Houwelingen, H. C., & Putter, H. (2008). Dynamic predicting by landmarking as an alternative for multi-state modeling: An application to acute lymphoid leukemia data. Lifetime Data Analysis, 14, 447–463.

    Article  MathSciNet  MATH  Google Scholar 

  • Van Houwelingen, H. C., & Putter, H. (2011). Dynamic prediction in clinical survival analysis. Boca Raton: Chapman and Hall/CRC Press.

    Google Scholar 

  • Van Imhoff, E. (1990). The exponential multidimensional demographic projection model. Mathematical Population Studies, 2(3), 171–182.

    Article  MATH  Google Scholar 

  • Weidlich, W., & Haag, G. (1983). Concepts and models of quantitative sociology: The dynamics of interacting populations. Berlin: Springer.

    Book  MATH  Google Scholar 

  • Willekens, F. J. (1987). The marital status life-table. In J. Bongaarts, T. Burch, & K. W. Wachter (Eds.), Family demography: Models and applications (pp. 125–149). Oxford: Clarendon Press.

    Google Scholar 

  • Willekens, F. J. (2009). Continuous-time microsimulation in longitudinal analysis. In A. Zaidi, A. Harding, & P. Williamson (Eds.), New frontiers in microsimulation modelling (pp. 413–436). Surrey: Ashgate.

    Google Scholar 

  • Willekens, F. (2013a). Biograph: Explore life histories.

    Google Scholar 

  • Willekens, F. (2013b). Chronological objects in demographic research. Demographic Research, 28(23), 649–680.

    Article  Google Scholar 

  • Wolf, D. A. (1986). Simulation methods for analyzing continuous-time event history models. Sociological Methodology, 16, 283–308.

    Article  Google Scholar 

  • Zinn, S. (2011). A continuous-time microsimulation and first steps towards a multi-level approach in demography. PhD dissertation, University of Rostock, Faculty of Informatics and Electrotechnics.

    Google Scholar 

  • Zinn, S. (2014). Package MicSim. Performing continuous-time microsimulation. Published on CRAN.

    Google Scholar 

  • Zinn, S., Himmelspach, J., Uhrmacher, A. M., & Gampe, J. (2013). Building Mic-Core, a specialized M&S software to simulate multi-state demographic micro models, based on JAMES II, a general M&S framework. Journal of Artificial Societies and Social Simulation, 16(3), 5.

    Google Scholar 

  • Gampe, J., Zinn, S., Willekens, F., Van der Gaag, N., de Beer, J., Himmelspach, J., & Uhrmacher, A. (2009, June). The microsimulation tool of the MicMac project. Paper presented at the 2nd general conference of the international microsimulation association, Ottawa.

    Google Scholar 

  • Allignol, A. (2014). Package etm. Empirical transition matrix. Published on CRAN.

    Google Scholar 

  • Jackson, C. (2014a). Package msm. Multi-state Markov and hidden Markov models in continuous time. Published on CRAN.

    Google Scholar 

  • Putter, H., de Wreede, L., & Fiocco, M. (2011). Package mstate. Data preparation, estimation and prediction in multistate models. Published on CRAN.

    Google Scholar 

  • Weidlich, W., & Haag, G. (Eds.). (1988). Interregional migration. Dynamic theory and comparative analysis. Berlin: Springer.

    Google Scholar 

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Willekens, F. (2014). Life Histories: Real and Synthetic. In: Multistate Analysis of Life Histories with R. Use R!. Springer, Cham. https://doi.org/10.1007/978-3-319-08383-4_2

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