Skip to main content
  • 1154 Accesses

Abstract

Garlic is an erect herb of the ALLIACEAE family, 30 to 60 cm tall. Bulb is on a disklike stem, consisting of several segments (cloves), enclosed in a common membrane that is at the base of foliage leaves. Each clove consists of a protective cylindrical sheath and a small central bud. Leaf blade is linear, flat, and solid, 1 to 2.5 cm wide, and 30 to 60 cm long, having an acute apex. Leaf sheaths form a pseudostem. Inflorescence is umbellate, having smooth scape, round, solid coiled at first; subtended by membranous, long-beaked spathe, splitting on one side and remaining attachedto umbel. Small bulbils are produced in inflorescence; flowers are variable in number, and sometimes absent; they seldom open and may wither in bud.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. J Agri Food Chemistry 1992; Vol. 40.

    Google Scholar 

  2. J Agri Food Chemistry 1992; Vol. 37.

    Google Scholar 

  3. Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co., Milwaukee, WI. 1990; 399 pp.

    Google Scholar 

  4. USDA Agricultural Handbook No. 8 and sequels; strictly nutritional data.

    Google Scholar 

  5. Pedersen, M. Nutritional Herbology. Pederson Publishing, Bountiful, UT 1987; 377 pp.

    Google Scholar 

  6. Wasuwat, S., M. Mokhasmith, P. Wannissorn, C. Sankamnoed and P. Bamphenwatana. Research and development on water-soluble, natural garlic concentrated powder (garlic natura). Abstr 10th Conference of Science and Technology 1984; 220–221.

    Google Scholar 

  7. Kodera, Y., H. Matsuura, S. Yoshida, T. Sumida, Y. Itakura, T. Fuwa and H. Nishino. Allixin, a stress compound from garlic. Chem Pharm Bull 1989; 37(6): 1656–1658.

    Article  CAS  Google Scholar 

  8. Glasby, J. H. Dictionary of Plants Containing Secondary Metabolites. Taylor and Francis, New York, 1991; 488 pp.

    Google Scholar 

  9. List, P. H. and L. Horhammer. Hager’s Handbuck der Pharmazeutischen Praxis. Vols 2–6, Springer-Verlag, Berlin, 1969–1979.

    Google Scholar 

  10. Lorenzo Velasquez, B., B. Sanchez, F. Murias and C. Dominguez Mijan. Garlic extract as an oxtocic substance. Arch Inst Farmacol Exp 1958; 10: 10–14.

    Google Scholar 

  11. Mateo Tinao, M. and R. Calvo Terren. Actions of Allium sativum (Garlic) and combinations on uterine motility. Arch Inst Farmacol Exp 1955; 8: 127.

    Google Scholar 

  12. Podolsky, E. The hypotensive properties of Allium sativum. Ill Med J 1938; 74: 176.

    Google Scholar 

  13. Rolleri, F. Occurrence of nicotinic acid and nicotinamide in curative plants. Arch Pharm 1943; 281: 118.

    Article  CAS  Google Scholar 

  14. Weisberger, A. S. and J. Pensky. Tumor-inhibiting effects derived from an active principle of garlic (Allium sativum). Science 1957; 126: 1112.

    Article  PubMed  CAS  Google Scholar 

  15. Asprey, G. F. and P. Thornton. Medicinal Plants of Jamaica Part I. West Indian Med J 1953; 2(4): 233–252.

    Google Scholar 

  16. Steggerda, M. and B. Korsch. Remedies for diseases as prescribed by Maya Indian herb-doctors. Bull Hist Med 1943; 13: 54.

    Google Scholar 

  17. Fitzpatrick, F. K. Plant substances active against Mycobacterium tuberculosis. Antibiot Chemother 1954; 4: 528.

    CAS  Google Scholar 

  18. Saha, J. C., E. C. Savini and S. Kasinathan. Ecbolic properties of Indian medicinal plants: Part I. Indian J Med Res 1961; 49: 130–151.

    CAS  Google Scholar 

  19. Shattuck, G. C. The Peninsula of Yucatan: Medical, Biological, Meteorological and Sociological Studies. 1933.

    Google Scholar 

  20. Saha, J. C. and S. Kasinathan. Ecbolic properties of Indian medicinal plants: Part II. Indian J Med Res 1961; 49: 1094–1098.

    PubMed  CAS  Google Scholar 

  21. Prasad, D. N., S. K. Bhattacharya and P. K. Das. A study of antinflammatory activity of some indigenous drugs in albino rats. Indian J Med Res 1966; 54: 582.

    PubMed  CAS  Google Scholar 

  22. Di Paolo, J. and C. Carruthers. The effect of allicin from garlic on tumor growth. Cancer Res 1960; 20: 431.

    Google Scholar 

  23. Ibragimov, F. I. and V. S. Ibragimov. Principal remedies of Chinese medicine. Foreign Technology Div, Air Force Systems Command, Wright-Patterson Air Force Base, 1964.

    Google Scholar 

  24. Jochle, W. Menses-inducing drugs: Their role in antique, medieval and renaissance gynecology and birth control. Contraception 1974; 10: 425–439.

    Article  PubMed  CAS  Google Scholar 

  25. Bhakuni, O. S., M. L. Dhar, M. M. Dhar, B. N. Dhawan and B. N. Mehrotra. Screening of Indian plants for biological activity: Part II. Indian J Exp Biol 1969; 7: 250–262.

    PubMed  CAS  Google Scholar 

  26. Lawrendiadis, G. Contribution to the knowledge of the medicinal plants of Greece. Planta Med 1961; 9: 164.

    Article  CAS  Google Scholar 

  27. Kroning, F. Garlic as an inhibitor for spontaneous tumors in mice. Acta Unio Intern Contra Cancrum 1964; 20: 855.

    Google Scholar 

  28. Kimura, Y. and K. Yamamoto. Cytologi-cal effect of chemicals on tumors. XXIII: Influence of crude extracts from garlic and some related species on MTK-Sar-coma III.Gann 1964;55:325.

    PubMed  CAS  Google Scholar 

  29. Sharaf, A. Food plants as a possible factor in fertility control. Qual Plant Mater Veg 1969; 17: 153.

    Article  CAS  Google Scholar 

  30. Krishnakumari, M. K. and S. K. Majumder. Bioassay of piperazine and some plant products with earthworms. J Sci Ind Res-C 1960; 19: 202.

    Google Scholar 

  31. Watt, J. M. and M. G. Breyer-Brand-wijk. The Medicinal and Poisonous Plants of Southern and Eastern Africa, 2nd Edition. South African Inst Med Research 1962.

    Google Scholar 

  32. Maruzzella, J. C., D. Scrandis, J. B. Scrandis and G. Grabon. Action of odoriferous organic chemicals and essential oils on wood-destroying fungi. Plant Dis Rept 1960; 44: 789.

    CAS  Google Scholar 

  33. Maruzzella, J. C. and J. Balter. The action of essential oils on phytopatho-genic fungi. Plant Dis Rept 1959; 43: 1143–1147.

    CAS  Google Scholar 

  34. Burkill, I. H. Dictionary of the Economic Products of the Malay Peninsula: Vol. I.Ministry of Agriculture and Cooperatives, Kuala Lumpur 1966.

    Google Scholar 

  35. Walter-Levy, L. and R. Strauss. Inorganic deposits in plants. C R Acad Sci 1954; 239: 897.

    CAS  Google Scholar 

  36. Petkov, V. Pharmacological and clinical studies of garlic. Dtsch Apoth Ztg 1966; 51: 1861–1867.

    Google Scholar 

  37. Uemori, T. Pharmacological investigation of Allium sativum. Nippon Yakurigaku Zasshi 1929; 9(1): 21–26.

    CAS  Google Scholar 

  38. Jain, R. C., C. R. Vyas and O. P. Mahatma. Hypoglycemic action of onion and garlic. Lancet 1973; 1491.

    Google Scholar 

  39. Stein, D. and M. H. Kotin. Clinical studies with Allium sativum (garlic). New York Physician 1937.

    Google Scholar 

  40. Sendl, A. and H. Wagner. Isolation and identification of homologues of ajoene and alliin from bulb-extracts of Allium ursinum. Planta Med 1991; 57(4): 361–362.

    Article  PubMed  CAS  Google Scholar 

  41. Mutsch-Eckner, M., B. Meier, A. D. Wright and O. Sticher. Gamma-glutamyl peptides from Allium sativum bulbs. Phytochemistry 1992; 31(7):2389–2391.

    Article  Google Scholar 

  42. Kaku, H., I. J. Goldstein, E. M. Van Damme and W. J. Peumans. New man-nose-specific lectins from garlic (Allium sativum) and ramsons (Allium ursinum) bulbs. Carbohydr Res 1992; 229(2): 347–353.

    Article  PubMed  CAS  Google Scholar 

  43. Lund, B. M. and G. D. Lyon. Detection of inhibitors of Erwinia carotovora and E. herbicola on thin-layer chromato-grams. J Chromatogr 1975; 110: 193.

    Article  PubMed  CAS  Google Scholar 

  44. Fletcher, R. D., B. Parker and M. Hassett. Inhibition of coagulase activity and growth of Staphylococcus aureus by garlic extracts. Folia Microbiol 1974; 19: 494.

    Article  CAS  Google Scholar 

  45. Jain, R. C. and C. R. Vyas. Garlic in alloxan-induced diabetic rabbits. Amer J Clin Nutr 1975; 28: 684.

    PubMed  Google Scholar 

  46. Kaleysa Raj, R. Screening of indigenous plants for anthelmintic action against human Ascaris lumbricoides: Part II. Indian J Physiol Pharmacol 1975; 19: 47–49.

    Google Scholar 

  47. Du, C. T. and F. J. Francis. Anthocya-nins from garlic (Allium sativum). J Food Sci 1975; 40: 1101.

    Article  CAS  Google Scholar 

  48. GRAS status of foods and food additives. Fed Regist 1976; 41: 38644.

    Google Scholar 

  49. Uchida, Y., T. Takahashi and N. Sato. The characteristics of the antibacterial activity of garlic. Jap J Antibiot 1975; 28: 638.

    CAS  Google Scholar 

  50. Sharma, K. K., N. K. Chowdhury and A. L. Sharma. Long term effect of onion on experimentally induced hypercholesteremia and consequently decreased fibrinolytic activity in rabbits. Indian J Med Res 1975; 64: 1629.

    Google Scholar 

  51. Jain, R. C. Onion and garlic in experimental cholesterol induced atherosclerosis. Indian J Med Res 1976; 64: 1509.

    PubMed  CAS  Google Scholar 

  52. Devereux, G. A study of abortion in primitive societies. The Julian Press, 1976.

    Google Scholar 

  53. Gupta, R. K. and S. Gupta. Purification of the hypoglycemic principle of onion. IRCS Libr Compend 1976; 4:410.

    CAS  Google Scholar 

  54. Yamazaki, M. and T. Nishimura. Induction of neutrophil accumulation by vegetable juice. Biosci Biotech Biochem 1992; 56(1): 150–151.

    Article  CAS  Google Scholar 

  55. Ip, C., D. Lisk and G. S. Stoewsand. Mammary cancer prevention by regular garlic and selenium-enriched garlic. Nutr Cancer 1992; 17(3): 279–286.

    Article  PubMed  CAS  Google Scholar 

  56. Rajendran, B. and M. Gopalan. Note on the insecticidal properties of certain plant extracts. Indian J Agr Sci 1979; 49: 295–297.

    Google Scholar 

  57. Sklan, D., Y. N. Berner and H. D. Rabinowitch. The effect of dietary onion and garlic on hepatic lipid concentrations and activity of antioxidative enzymes in chicks. J Nutr Biochem 1992; 3(7): 322–325.

    Article  CAS  Google Scholar 

  58. Sendl, A., M. Schliack, R. Loser, F. Stanislaus and H. Wagner. Inhibition of cholesterol synthesis in vitro by extracts and isolated compounds prepared from garlic and wild garlic. Atherosclerosis 1992; 94(1): 79–85.

    Article  PubMed  CAS  Google Scholar 

  59. Alnaqeeb, M. A., M. Ali, M. Thomson, S. H. Khater, S. A. Gomes and J. M. Al-Hassan. Histopathologi-cal evidence of protective action of garlic against collagen and archidonic acid toxicity in rabbits. Prostaglandins Leukotrienes Essent Fatty Acids 1992; 46(4): 301–306.

    Article  CAS  Google Scholar 

  60. Mahmoud, I., A. Alkofahi and A. Abdelaziz. Mutagenic and toxic activities of several spices and some Jordanian medicinal plants. Int J Pharmacog 1992; 30(2): 81–85.

    Article  Google Scholar 

  61. Egen-Schwind, C., R. Eckard and F. H. Kemper. Metabolism of garlic constituents in the isolated perfused rat liver. Planta Med 1992; 58(4): 301–305.

    Article  PubMed  CAS  Google Scholar 

  62. Liu, J. Z., R. I. Lin and J. A. Milner. Inhibition of 7,12-dimethylbenz-[A]athracene-induced mammary tumors and DNA adduct by garlic powder. Carcinogenesis 1992; 13(10): 1847–1851.

    Article  PubMed  CAS  Google Scholar 

  63. Bilgrami, K. S., K. K. Sinha and A. K. Sinha. Inhibition of aflatoxin production and growth of Aspergillus flavus by eugenol and onion and garlic extracts. Indian J Med Res 1992; 96(34): 171–175.

    PubMed  CAS  Google Scholar 

  64. Sheela, C. G. and K. T. Augusti. Antidiabetic effects of S-allyl cysteine sulphoxide isolated from garlic (Allium sativum Linn.). Indian J Exp Biol 1992; 30(6): 523–526.

    PubMed  CAS  Google Scholar 

  65. Huang, M. F., W. J. Hang and Q. Zhong. Hair growth stimulating preparations containing medicinal plant extracts. Patent-Faming Zhuanli Shening Gongkai Shuomingshu 1990; 1,043,624:6 pp.

    Google Scholar 

  66. Weber, N. D., D. O. Anderson, J. A. North, B. K. Murray, L. D. Lawson and B. G. Hughes. In vitro virucidal effects of Allium sativum (garlic) extract and compounds. Planta Med 1992; 58(5): 417–423.

    Article  PubMed  CAS  Google Scholar 

  67. Bhat, R. B., E. O. Eterjere and V. T. Oladipo. Ethnobotanical studies from Central Nigeria. Econ Bot 1990; 44(3): 382–390.

    Article  Google Scholar 

  68. Fields, M., C. G. Lewis and M. D. Lure. Garlic oil extract ameliorates the severity of copper deficiency. J Amer Coll Nutr 1992; 11(3): 334–339.

    CAS  Google Scholar 

  69. Huang, M. F., W. J. Hang and Q. Zhong. Hair growth stimulating preparations containing medicinal plant extracts. Patent-Faming Zhuanli Shenqing Gongkai Shuomingshu 1990; 1,043,624: 6pp.

    Google Scholar 

  70. Horie, T., S. Awazu, Y. Itakura and T. Fuwa. Identified diallyl polysulfides from an aged garlic extract which protects the membranes from lipid peroxidation. Planta Med 1992; 58(5): 468–469.

    Article  PubMed  CAS  Google Scholar 

  71. Weinberg, D. S., M. L. Manier, M. D. Richardson and F. G. Haibach. Identification and quantification of organo-sul-fur compliance markers in a garlic extract. J Agr Food Chem 1993; 41(1): 37–11.

    Article  CAS  Google Scholar 

  72. Rotzsch, W., F. Rassoulf and A. Walper. Postprandial lipaemia under treatment with Allium sativum/controlled double-blind study in health volunteers with reduced HDL2-Cho-lesterol levels. Arzneim-Forsch 1992; 42(10): 1223–1227.

    CAS  Google Scholar 

  73. Isensee, H., B. Rietz and R. Jacob. Cardioprotective actions of garlic (Allium sativum). Arzneim-Forsch 1993; 43(2): 94–98.

    CAS  Google Scholar 

  74. Venmadhi, S. and T. Devaki. Studies on some liver enzymes in rats ingesting ethanol and treated with garlic oil. Med Sci Res 1992; 20(20): 729–731.

    CAS  Google Scholar 

  75. McFadden, J. P., I. R. White and R. J. G. Rycroft. Allergic contact dermatitis from garlic. Contact Dermatitis 1992; 27(5): 333–334.

    Article  PubMed  CAS  Google Scholar 

  76. Adoga, G. I. and C. O. Ohaeri. Effect of garlic oil on prothrombin, thrombin and partial thromboplastin times in streptozotocin-induced diabetic rats. Med Sci Res 1991; 19: 407–408.

    CAS  Google Scholar 

  77. Legnani, C., M. Frascaro, G. Guazzaloca, S. Ludovici, G. Cesarano and S. Coccheri. Effects of a dried garlic preparation on fibrinolysis and platelet aggregation in health subjects. Arzneim-Forsch 1993; 43(2): 119–121.

    CAS  Google Scholar 

  78. Maeda, H., T. Katsuki, T. Akaike and R. Yasutake. High correlation between lipid peroxide radical and tumor-promoter effect: Suppression of tumor promotion in the Epstein-Barr virus/ B-lymphocyte. Jap J Cancer Res 1992; 83(9): 923–928.

    Article  CAS  Google Scholar 

  79. Yasukawa, K., A. Yamaguchi, J. Arita, S. Sakurai, A. Ikeda and M. Takido. Inhibitory effect of edible plant extracts on 12–0-tetradecanoylphorbol-13-acetate-induced ear oedema in mice. Phytother Res 1993; 7(2): 185–189.

    Article  CAS  Google Scholar 

  80. Roychoudhury, A., T. Das, A. Sharma and G. Talukder. Use of crude extract of garlic (Allium sativum L.) in reducing cytotoxic effects of arsenic in mouse bone marrow. Phytother Res 1993; 7(2): 163–166.

    Article  Google Scholar 

  81. Reddy, M. B., K. R. Reddy and M. N. Reddy. A survey of plant crude drugs of Anantapur district, Andhra Pradesh, India. Int J Crude Drug Res 1989; 27(3): 145–155.

    Google Scholar 

  82. Martin, N., L. Bardisa, C. Pantoja, R. Roman and M. Vargas. Experimental cardiovascular depressant effects of garlic (Allium sativum) dialysate. J Ethno-Pharmacol 1992; 37(2): 145–149.

    CAS  Google Scholar 

  83. Guo, N. L, D. P. Lu, G. Woods, E. Reed, G. Z. H. Zhou, L. B. Zhang and R. Waldman. Demonstration of the antiviral activity of garlic extract against human cytomegalovirus in vitro. Chin Med J 1993; 106(2): 93–96.

    PubMed  CAS  Google Scholar 

  84. Das, T., A. Roychoudhury, A. Sharma and G. Talukder. Modification of clastogenicity of three known clastogens by garlic extract in mice in vivo. Environ Molec Mutagen 1993; 21(4): 383–388.

    Article  CAS  Google Scholar 

  85. Consoli, R. A. G. B., N. M. Mendes, J. P. Pereira, B. D. S. Santos and M. A. Lamounier. Properties of plant extracts against Aedes fluviatilis (Lutz) (Diptera: Culcidae) in the laboratory. Mem Inst Oswaldo Cruz 1988; 83(1): 87–93.

    Article  PubMed  CAS  Google Scholar 

  86. R. C. Jain. Antitubercular activity of garlic oil. Indian Drugs 1993; 30(2): 73–75.

    CAS  Google Scholar 

  87. Sekiya, K., T. Fushimi, T. Kanamori, N. Ishikawa, M. Itoh, M. Takita and T. Nakanishi. Regulation of arachi-donic acid metabolism in platelets by vegetables. Biosci Biotech Biochem 1993; 57(4): 670–671.

    Article  Google Scholar 

  88. Gebhart, R. Multiple inhibitory effects of garlic extracts on cholesterol biosynthesis in hepatocytes. Lipids 1993; 28(7): 613–619.

    Article  Google Scholar 

  89. McMahon, F. G. and R. Vargas. Can garlic lower blood pressure? A pilot study. Pharmacotherapy 1993; 13(4): 406–407.

    PubMed  CAS  Google Scholar 

  90. Amagase, H. and J. A. Milner. Impact of various sources of garlic and their constituents on 7,12-dimethylbenz-[A]anthracene binding to mammary cell DNA. Carcinogenesis 1993; 14(8): 1627–1631.

    Article  PubMed  CAS  Google Scholar 

  91. Meding, B. Skin symptoms among workers in a spice factory. Contact Dermatitis 1993; 29(4): 202–205.

    Article  PubMed  CAS  Google Scholar 

  92. Koch, H. P., W. Jager, U. Groh, J. E. Hovie, G. Plank, U. Sedlak and W. Praznik. Carbohydrates from garlic bulbs (Allium sativum L.) as inhibitors of adenosine deaminase enzyme activity. Phytother Res 1993; 7(5): 387–389.

    Article  CAS  Google Scholar 

  93. Ohsumi, C., T. Hayashi, K. Kubota and A. Kobayashi. Volatile flavor compounds formed in an interspecific hybrid between onion and garlic. J Agr Food Chem 1993; 41(10): 1808–1810.

    Article  CAS  Google Scholar 

  94. Deshpande, R. G., M. B. Khan, D. A. Bhat and R. G. Navalkar. Inhibition of Mycobacterium avium complex isolates from AIDS patients by garlic (Allium sativum). J Antimicrob Chemother 1993; 32(4): 623–626.

    Article  PubMed  CAS  Google Scholar 

  95. Jin, H. P., et al. Protective effect of diallyl sulfide, a natural extract of garlic, on mnng-induced damage of rat glandular stomach mucosa. Chung’ hua Chung Liu Tsa Chih 1990; 12(6): 429–431.

    Google Scholar 

  96. Kiesewetter, H., F. Jung, E. M. Jung, C. Mrowietz, J. Koscielny and E. Wenzel. Effect of garlic on platelet aggregation in patients with increased risk of juvenile ischaemic attack. Eur J Clin Pharmacol 1993; 45(4): 333–336.

    Article  PubMed  CAS  Google Scholar 

  97. Jood, S., A. C. Kapoor and R. Singh. Evaluation of some plant products against Trogoderma granarium everts in stored maize and their effects on nutritional composition and organoleptic characteristic of kernels. J Agr Food Chem 1993; 41(10): 1644–1648.

    Article  CAS  Google Scholar 

  98. Anesini, C. and C. Perez. Screening of plants used in Argentine folk medicine for antimicrobial activity. J Ethnopharmacol 1993; 39(2): 119–128.

    Article  PubMed  CAS  Google Scholar 

  99. Morioka, N., L. L. Sze, D. L. Morton and R. F. Irie. A protein fraction from aged garlic extract enhances cytotoxicity and proliferation of human lymphocytes mediated by interleukin-2 and concanavalin A. Cancer Immunol Immunother 1993; 37(5): 316–322.

    Article  PubMed  CAS  Google Scholar 

  100. Seuri, M., A. Taivanen, P. Ruoppi and H. Tukiainen. Three cases of occupational asthma and rhinitis caused by garlic. Clin Exp Allergy 1993; 23(12): 1011–1014.

    Article  PubMed  CAS  Google Scholar 

  101. Rosin, S., H. Tuorila and A. Uutela. Garlic: a sensory pleasure or a social nuisance? Appetite 1992; 19: 133–143.

    Article  PubMed  CAS  Google Scholar 

  102. Gwilt, P. R., C. L. Lear, M. A. Tempero, D. D. Birt, A. C. Grandjean, R. W. Ruddon and D. L. Nagel. The effect of garlic extract on human metabolism of acetominophen. Cancer Epidemiol Biomarkers Prevention 1994; 3(2): 155–160.

    CAS  Google Scholar 

  103. El-Mofty, M. M., S. A. Sakr, A. Essawy and H. S. A. Gawad. Preventive action of garlic on anatoxin Bl-induced carcinogenesis in the toad Bufo regularis. Nutr Cancer 1994; 21(1): 95–100.

    Article  PubMed  CAS  Google Scholar 

  104. Reeve, V. E., M. Bosnic, E. Rozinova and C. Boehm-Wilcox. A garlic extract protects from ultraviolet B (280–320 nm) radiation-induced suppression of contact hypersensitivity. Photochem Photobiol 1993; 58(6): 813–817.

    Article  PubMed  CAS  Google Scholar 

  105. Hong, S. K., S. D. Koh, H. K. Shin and K. S. Kim. Effects of garlic oil, garlic juice and allyl sulfide on the responsiveness of dorsal horn cell in the cat. Hanyang Uidae Haksulchi 1992; 12(2): 621–633.

    CAS  Google Scholar 

  106. Soni, K. B., A. Rajan and R. Kuttan. Reversal of aflatoxin-induced liver damage by turmeric and curcumin. Cancer Lett 1992; 66(2): 115–121.

    Article  PubMed  CAS  Google Scholar 

  107. Ali, M., M. Angelo-Khattar, A. Farid, R. A. H. Hassan and O. Thulesius. Aqueous extracts of garlic (Allium sativum) inhibit prostaglandin synthesis in the ovine ureter. Prostagladins Leukotrienes Essent Fatty Acids 1993; 49(5): 855–859.

    Article  CAS  Google Scholar 

  108. Lee, Y. S. and J. J. Jang. Modifying effect of garlic and red pepper extracts on diethylnitrosamine-induced hepatocarcinogenesis. Environ Mutagens Carcinog 1991; 11(1):21–28.

    CAS  Google Scholar 

  109. Das, T., A. R. Choudhury, A. Sharma and G. Talkdr. Modification of cytotoxic effects of inorganic arsenic by a crude extract of Allium sativum L. in mice. Int J Pharmacog 1993; 31(4): 316–320.

    Article  Google Scholar 

  110. Burger, R. A., R. P. Warren, L. D. Lawson and B. G. Hughes. Enhancement of in vitro human immune function by Allium sativum L. (garlic) fractions. Int J Pharmacog 1993; 31(3): 169–174.

    Article  CAS  Google Scholar 

  111. Sogani, R. K. and K. Katoch. Correlation of serum cholesterol levels and incidence of myocardial infarction with dietary onion and garlic eating habits. J Asso Phys Ind 1981; 29(6): 443–446.

    CAS  Google Scholar 

  112. Silagy, C. A. and H. A. W. Neil. A meta-analysis of the effect of garlic on blood pressure. J Hypertension 1994; 12(4): 463–468.

    Article  CAS  Google Scholar 

  113. Yeh, Y. Y. and S. M. Yeh. Garlic reduces plasma lipids by inhibiting hepatic cholesterol and triacylglycerol synthesis. Lipids 1994; 29(3): 189–193.

    Article  PubMed  CAS  Google Scholar 

  114. Svendsen, L., S. I. S. Rattan and B. F. C. Clark. Testing garlic for possible anti-aging effects on long-term growth characteristics, morphology and mac-romolecular synthesis of human fibroblasts. J Ethnopharmacol 1994; 43(2): 125–133.

    Article  PubMed  CAS  Google Scholar 

  115. Soni, K. B., A. Rajan and R. Kuttan. Inhibition of aflatoxin-induced liver damage in ducklings by food additives. Mycotoxin Res 1993; 9(1): 22–27.

    Article  CAS  Google Scholar 

  116. Perez, C. and C. Anesini. Inhibition of Pseudomonas aeruginosa by Argentinean medicinal plants. Fitoterapia 1994; 65(2): 169–172.

    Google Scholar 

  117. Lim-Sylianco, C. Y., J. A. Concha, A. P. Jocano and C. M. Lim. Antimu-tagenic effects of eighteen Philippine plants. Philippine J Sci 1986; 115(4): 293–296.

    Google Scholar 

  118. Heinle, H. and E. Betz. Effects of dietary garlic supplementation in a rat model of atherosclerosis. Arzneim-Forsch 1994; 44(5); 614–617.

    CAS  Google Scholar 

  119. Kojima, R., Y. Toyama and S. T. Ohnishi. Protective effects of an aged garlic extract on doxyrubicin-induced cardiotoxicity in the mouse. Nutr Cancer 1994; 22(2): 163–173.

    Article  PubMed  Google Scholar 

  120. Ozturk, Y., S. Aydin, M. Kosar and K. H. C. Baser. Endothelium-dependent and independent effects of garlic on rat aorta. J Ethnopharmacol 1994; 44(2): 109–116.

    Article  PubMed  CAS  Google Scholar 

  121. Singh, J., A. K. Dubey and N. N. Tripathi. Antifungal activity of Mentha spicata. Int J Pharmacog 1994; 32(4): 314–319.

    Article  CAS  Google Scholar 

  122. Burden, A. D., S. M. Wilkinson, M. H. Beck and R. J. G. Chalmers. Garlic-induced systemic contact dermatitis. Contact Dermatitis 1994; 30(5): 299–300.

    Article  PubMed  CAS  Google Scholar 

  123. Imai, J., N. Ide, S. Nagge, T. Moriguchi, H. Matsuura and Y. Itakura. Antioxidant and radical scavenging effects of aged garlic extract and its constituents. Planta Med 1994; 60(5): 417–420.

    Article  PubMed  CAS  Google Scholar 

  124. Torok, B., J. Belagyi, B. Rietz and R. Jacob. Effectiveness of garlic on the radical activity in radical generating systems. Arzneim-Forsch 1994; 44(5): 608–611.

    CAS  Google Scholar 

  125. Popov, I., A. Blumstein and G. Lewin. Antioxidant effects of aqueous garlic extract. Arzneim-Forsch 1994; 44(1): 602–604.

    CAS  Google Scholar 

  126. Canduela, V., I. Mongil, M. Carrascosa, S. Docio and P. Cagigas. Garlic: Always good for health? Brit J Dermatol 1995; 132(1): 161–162.

    Article  CAS  Google Scholar 

  127. Davis, L. E., J. K. Shen and R. E. Royer. In vitro synergism of concentrated Allium sativum extract and amphotericin B against Cryptococcus neoformans. Planta Med 1994; 60(6): 546–549.

    Article  PubMed  CAS  Google Scholar 

  128. Yamasaki, T., L. Li and B. H. S. Lau. Garlic compounds protect vascular endothelial cells from hydrogen peroxide-induced oxidant injury. Phytother Res 1994; 8(7): 408–412.

    Article  CAS  Google Scholar 

  129. Saradeth, T., S. Seidl, K. L. Resch and E. Ernst. Does garlic alter the lipid pattern in normal volunteers? Phytomedicine 1994; 1(3): 183–185.

    Article  CAS  Google Scholar 

  130. Kenzelmann, R. and F. Kade. Limitation of the deterioration of lipid parameters by a standardized garlic-ginkgo combination product. A multicenter placebo-controlled double-blind study. Arzneim-Forsch 1993; 43(9): 978–981.

    CAS  Google Scholar 

  131. Venugopal, P. V. and T. V. Venugopal. Antidermatophytic activity of garlic (Allium sativum) in vitro. Int J Dermatol 1995; 34(4): 278–279.

    Article  PubMed  CAS  Google Scholar 

  132. Thomas, D. J. and K. L. Parkin. Quantification of alk(en)yl-L-cysteine sulfoxides and related amino acids in alliums by high-performance liquid chromatography. J Agr Food Chem 1994; 42(8): 1632–1638.

    Article  CAS  Google Scholar 

  133. Simons, L. A., S. Balasubramaniam, M. Von Konigsmark, A. Parfitt, J. Simons and W. Peters. On the effect of garlic on plasma lipids and lipoproteins in mild hypercholesterolaemia. Atherosclerosis 1995; 113(2): 219–225.

    Article  PubMed  CAS  Google Scholar 

  134. Moriguchi, T., K. Takashina, P. J. Chu, H. Saito and N. Nishiyama. Prolongation of life span and improved learning in the senescence accelerated mouse produced by aged garlic extract. Biol Pharm Bull 1994; 17(12): 1589–1594.

    Article  PubMed  CAS  Google Scholar 

  135. DeBlasi, V., S. Debrot, P. A. Menoud, L. Gendre and J. Schowing. Amoe-bicidal effect of essential oils in vitro. J Toxicol Clin Exp 1990; 10(6): 361–373.

    CAS  Google Scholar 

  136. Ariga, T., T. Seki, K. Ando, S. Teramoto and H. Nishimura. Antiplatelet principle found in the essential oil of garlic (Allium sativum L.) and its inhibition mechanism. Dev Food Eng Proc Int Congr Eng Food 6th 1993; 2: 156–158.

    Google Scholar 

  137. Das, L, N. S. Khan and S. R. Sooranna. Potent activation of nitric oxide synthase by garlic: a basis for its therapeutic applications. Current Med Res Opinion 1995; 13(5): 257–263.

    Article  CAS  Google Scholar 

  138. Lichtenstein, L. M. and W. C. Pickett. Treatment of allergies and inflammatory conditions. Patent-Eur Pat Appl 1985; 153,881: 21pp.

    Google Scholar 

  139. Melzig, M. F., E. Krouse and S. Franke. Inhibition of adenosine deaminase activity of aortic endothelial cells by extracts of garlic (Allium sativum L.). Pharmazie 1995; 50(5): 359–361.

    PubMed  CAS  Google Scholar 

  140. Oi, Y., T. Kawada, K. Kitamura, F. Oyama, M. Nitta, Y. Kominato, S. Nishimura and K. Iwai. Garlic supplementation enhances norepinephrine secretion, growth of brown adipose tissue, and triglyceride catabolism in rats. Nutr Biochem 1995; 6(5): 250–255.

    Article  CAS  Google Scholar 

  141. Kasuya, S., C. Goto and H. Ohtomo. Studies on prophylaxis against anisakiasis-A screening of killing effects of extracts from foods on the larvae. Kansensh Ogaku Zasshi 1988; 62(12): 1152–1156.

    CAS  Google Scholar 

  142. German, K., U. Kumar and H. N. Blackford. Garlic and the risk of turp bleeding. Brit J Urol 1995; 76(4): 512.

    Article  Google Scholar 

  143. Akema, R., N. Okazaki and K. Takizawa. Antibacterial substance in commercial Allium plants. Kanagawa-ken Eisei Kenkyusho Kenkyu Hokoku 1987; 17: 39–40.

    Google Scholar 

  144. G. Gazzani. Anti- and pro-oxidant activity of some vegetables in the Mediterranean diet. Riv Sci Aliment 1994; 23(3): 413–420.

    CAS  Google Scholar 

  145. Hsu, W. C. Garlic slice in repairing eardrum perforation. Chung Hua I Hsueh Tsa Chih 1977; 3: 204.

    CAS  Google Scholar 

  146. Augusti, K. T. Hypocholesterolemic effect of garlic (Allium sativum), Indian J Exp Biol 1977; 15: 489.

    PubMed  CAS  Google Scholar 

  147. Alami, R., A. Macksad and A. R. El-gindy. Medicinal Plants in Kuwait. Al-Assiriya Printing, 1976.

    Google Scholar 

  148. Das, N. N., A. Das and A. K. Mukherjee. Structure of the D-galactan isolated from garlic (Allium sativum) bulbs. Carbohydr Res 1977; 56: 337.

    Article  PubMed  CAS  Google Scholar 

  149. Bordia, A. K., H. K. Joshi, Y. K. Sanadhya and N. Bhu. Effect of essential oil of garlic on serum fibrinolytic activity in patients with coronary artery disease. Atherosclerosis 1977; 28: 155–159.

    Article  PubMed  CAS  Google Scholar 

  150. Moore, G. S. and R. D. Atkins. The fungicidal and fungistatic effects of an aqueous garlic extract on medically important yeast-like fungi. Mycologia 1977; 69: 341.

    Article  PubMed  CAS  Google Scholar 

  151. Barone, F. E. and M. R. Tansey. Isolation, purification, identification, synthesis, and kinetics of activity of the anticandidal component of Allium sativum, and a hypothesis for its mode of action. Mycologia 1977; 69: 793.

    Article  PubMed  CAS  Google Scholar 

  152. Block, E., S. Ahmad, M. K. Jain, R. W. Crecely, R. Apitz-Castro and M. R. Cruz. (E,E)-Ajoene: a potent antithrombotic agent from garlic. J Amer Chem Soc 1984; 106(26): 8295–8296.

    Article  CAS  Google Scholar 

  153. Zhao, S. Q. and L. Wang. Transformation of the main components of garlic during low-temperature controlled-atmosphere storage. Xibei Shifan Xueyuan Xuebao Ziran Kexueban 1983; 1983(1): 70–79.

    Google Scholar 

  154. Miething, H. Allicin and oil in garlic bulbs — HPLC quantitative determination. Dtsch Apoth Ztg 1985; 125(41): 2049–2050.

    CAS  Google Scholar 

  155. Miller, J. R., M. O. Harris and J. A. Breznak. Search for potent attractants of onion flies. J Chem Ecol 1984; 10(10): 1477–1488.

    Article  CAS  Google Scholar 

  156. Voigt, M. and E. Wolf. Garlic HPLC determination of garlic components in extracts, powder, and pharmaceuticals. Dtsch Apoth Ztg 1986; 126(12): 591–593.

    CAS  Google Scholar 

  157. Block, E., S. Ahmad, J. L. Catalfamo, M. K. Jain and R. Apitz-Castro. Antithrombotic organosulfur compounds from garlic: structural, mechanistic and synthetic studies. J Amer Chem Soc 1986; 108(22): 7045–7055.

    Article  CAS  Google Scholar 

  158. Vernin, G., J. Metzger, D. Fraisse and C. Scharff. GC-MS (EI, PCI, NCI) computer analysis of volatile sulfur compounds in garlic essential oils. Application of the mass fragmento-metry sim technique-1. Planta Med 1986; 1986(2): 96–101.

    Article  Google Scholar 

  159. Nitiyanant, W., S. Wasuwat, S. Ploybutr and S. Tandhanand. Effect of the dried powder extract, water soluble of garlic (Allium sativum) on cholesterol, triglyceride and high density lipoprotein in the blood. J Med Ass Thailand 1987; 70(11): 646–648.

    CAS  Google Scholar 

  160. Unnikrishnan, M. C. and R. Kuttan. Cytotoxicity of extracts of spices to cultured cells. Nutr Cancer 1988; 11(4): 251–257.

    Article  PubMed  CAS  Google Scholar 

  161. Joshi, D. J., R. K. Dikshit and S. M. Mansuri. Gastrointestinal actions of garlic oil. Phytother Res 1987; 1(3): 140–141.

    Article  Google Scholar 

  162. Mohammad, S. F. and S. C. Woodward. Characterization of a potent inhibitor of platelet aggregation and release reaction isolated from Allium sativum (garlic). Thrombosis Res 1986; 44(6): 793–806.

    Article  CAS  Google Scholar 

  163. Phonphok, C. Y. Effects of garlic extract on growth of various Candida species. J Natl Res Counc Thailand 1983; 15: 53–65.

    Google Scholar 

  164. Kasuga, S., A. Kanesawa and S. Nakagawa. Extraction of ajoene from garlic for treatment of liver diseases. Patent-Japan Kokai Tokkyo Koho 1988; 63 08,328: 5pp.

    Google Scholar 

  165. Takasugi, N., K. Kotoo, T. Fuwa and H. Saito. Effect of garlic on mice exposed to various stresses. Oyo Yakuri Phaiv macometrics 1984; 28(6): 991–1002.

    Google Scholar 

  166. Bojs, G. and A. Svensson. Contact allergy to garlic used for wound healing. Contact Dermatitis 1988; 18(3): 179–181.

    Article  PubMed  CAS  Google Scholar 

  167. De a Ribeiro, R., F. Barros, M. Margarida, R. F. Melo, C. Muniz, S. Chieia, M. G. Wanderley, C. Gomes and G. Trolin. Acute diuretic effects in conscious rats produced by some medicinal plants used in the state of Sao Paulo, Brasil. J Ethnopharmacol 1988; 24(1): 19–29.

    Article  Google Scholar 

  168. Lancaster, J. E., E. M. Dommisse and M. L. Shaw. Production of flavour precursors [S-alk(en)yl-L-cysteine sulphoxides] in photomixotrophic callus of garlic. Phytochemistry 1988; 27(7): 2123–2124.

    Article  Google Scholar 

  169. Ghannoum, M. A. Studies on the anticandidal mode of action of Allium sativum (garlic). J Gen Microbiol 1988; 134(11): 2917–2924.

    PubMed  CAS  Google Scholar 

  170. Sitprija, S., C. Plengvidhya, V. Kangkaya, S. Bhuvapanich and M. Tunkayoon. J Med Ass Thailand Suppl 1987; 70(2): 223–227.

    Google Scholar 

  171. Matsuura, H., T. Ushiroguchi, Y. Itakura, N. Hayashi and T. Fuwa. Chem Pharm Bull 1988; 36(9): 3659–3663.

    Article  CAS  Google Scholar 

  172. Al-Nagdy, S. A., M. O. Abdel-Rahman and H. I. Heiba. Evidence for some prostaglandins in Allium sativum extracts. Phytother Res 1988; 2(4): 196–197.

    Article  CAS  Google Scholar 

  173. You, W. C., W. J. Blot, Y. S. Chang, A. Ershow, Z. T. Yang, Q. An, J. F. Fraumeni, Jr. and T. G. Wang. Allium vegetable and reduced risk of stomach cancer. J Nat Cancer Inst 1989; 81(2): 162–164.

    Article  PubMed  CAS  Google Scholar 

  174. Pena, N., A. Auro and H. Sumano. A comparative trial of garlic, its extract and ammonium-potassium tartrate as anthelmintics in carp. J Ethnopharmacol 1988; 24(2/3): 199–203.

    Article  PubMed  CAS  Google Scholar 

  175. Pino, J., A. Rosado and A. Gonzalez. Volatile flower components of garlic essential oil. Acta Aliment 1991; 20 (3/4): 163–171.

    CAS  Google Scholar 

  176. Tanaka, Y., M. Kataoka, Y. Konishi, T. Nishmune and Y. Takagaki. Effects of vegetable foods on beta-hexosamini-dase release from rat basophilic leukemia cells (RBL-2H3). Jpn J Toxicol Environ Health 1992; 38(5): 418–424.

    Article  CAS  Google Scholar 

  177. Didry, N., M. Pinkas and L. Dubreuil. Antibacterial activity of species from the genus Allium. Pharmazie 1987; 42(10): 687–688.

    PubMed  CAS  Google Scholar 

  178. Qureshi, A. A, T. D. Crenshaw, N. Abuirmeileh, D. M. Peterson and C. E. Elson. influence of minor plant constituents on procine hepatic lipid metabolism. Atherosclerosis 1987; 64(2/3): 109–115.

    Article  PubMed  CAS  Google Scholar 

  179. Sharma, C. P. and M. C. Summy. Effects of garlic extracts and of three pure components isolated from it on human platelet aggregation, arachidonate metabolism, release reaction and platelet ultra-structure-comments. Throm-bosis Res 1988; 52(5): 492–494.

    Google Scholar 

  180. Mirelman, D., D. Monheit and S. Varon. Inhibition of growth of Entamoeba histolytica by allicin, the active principle of garlic extract (Allium sativum). J Infect Dis 1987; 156(1): 243–244.

    Article  PubMed  CAS  Google Scholar 

  181. Sadhana, A. S., A. R. Rao, K. Kucheria and V. Bijani. Inihibitory action of garlic oil on the initiation of benzo[a]pyrene-induced skin carcinogenesis in mice. Cancer Lett 1988; 40(2): 193–197.

    Article  PubMed  CAS  Google Scholar 

  182. Rashid, A., M. Hussain and H. H. Khan. Bioassay for prostaglandin-like activity of garlic extract using isolated rat fundus strip and rat colon preparation. J Pak Med Ass 1986; 36(6): 138–141.

    CAS  Google Scholar 

  183. Harenburg, J., C. Giese and R. Zimmermann. Effect of dried garlic on blood coagulation, fibrinolysis, platelet aggregation and serum cholesterol levels in patients with hyperlipoproteinemia. Atherosclerosis 1988; 74(3): 247–249.

    Article  Google Scholar 

  184. Singh, B. G. and S. C. Agrawal. Efficacy of odoriferous organic compounds on the growth of keratinophylic fungi. Curr Sci 1988; 57(14): 807–809.

    Google Scholar 

  185. Nishimo, H., A. Iwashima, Y. Itakura, H. Matsuura and T. Fuwa. Antitumor-promoting activity of garlic extracts. Oncology 1989; 46(4): 277–280.

    Article  Google Scholar 

  186. Srivastava, V. K. and Z. Afao. Garlic extract inhibits accumulation of polyols and hydration in diabetic rat lens. Curr Sci 1989; 58(7): 376–377.

    Google Scholar 

  187. Knasmuller, S., R. DeMartin, G. Domjan and A. Szakmary. Studies on the antimutagenic activities of garlic extract. Environ Molec Mutagen 1989; 13(4): 357–365.

    Article  CAS  Google Scholar 

  188. Kiviranta, J., K. Huovinen, T. Seppanen-Laakso, R. Hiltunen, H. Karppanen and M. Kilpelainen. Effects of onion and garlic extracts on spontaneously hypertensive rats. Phytother Res 1989; 3(4): 132–135.

    Article  Google Scholar 

  189. Ciplea, A. G. and K. D. Richter. The protective effect of Allium sativum and Crataegus on isoprenaline-induced tissue necroses in rats. Arzneim-Forsch 1988; 38(11): 1583–1592.

    CAS  Google Scholar 

  190. Shetty, S. A., H. S. Prakash and H. S. Shetty. Efficacy of certain plant extracts against seed-borne infection of Trichoconiella padwickii in paddy (Oryza sativa). Can J Bot 1989; 67(7): 1956–1958.

    Article  Google Scholar 

  191. Louria, D. B., M. Lavenhar, T. Kaminski and R. H. K. Eng. Garlic (Allium sativum) in the treatment of experimental cryptococcosis. J Med Vet Mycol 1989; 27(4): 253–256.

    Article  PubMed  CAS  Google Scholar 

  192. Tsuboi, S., S. Kishimoto and S. Ohmori. S-(2-carboxypropyl)-glu-tathione in vegetables in Liliflorae. J Agr Food Chem 1989; 37(3): 611–615.

    Article  CAS  Google Scholar 

  193. Tanira, M. O. M., A. M. Ageel and M. S. Al-Said. A study of some Saudi medicinal plants used as diuretics in traditional medicine. Fitoterapia 1989; 60(5): 443–447.

    Google Scholar 

  194. Zhang, Y. S., X. R. Chen and Y. N. Yu. Antimutagenic effect of garlic (Allium sativum L.) on 4NQO-induced mutagenesis in Escherichia coli WP2. Mutat Res l989; 227(4): 215–219.

    Article  PubMed  CAS  Google Scholar 

  195. Belman, S., J. Soloman, A. Segal, E. Block and G. Barany. Inhibition of soybean lipoxygenase and mouse skin tumor promotion by onion and garlic components. J Biochem Toxicol 1989; 4(3): 151–160.

    Article  PubMed  CAS  Google Scholar 

  196. Horie, T., T. Murayama, T. Mishima, F. Itoh, Y. Minamide, T. Fuwa and S. Awazu. Protection of liver microsomal membranes from lipid peroxidation by garlic extract. Planta Med 1989; 55(6): 506–508.

    Article  PubMed  CAS  Google Scholar 

  197. Aslam, M. and I. H. Stockley. Interaction between curry ingredient (karela) and drug (chlorpropamide). Lancet 1979; 607.

    Google Scholar 

  198. Matsuura, H., T. Ushiroguchi, Y. Itakura and T. Fuwa. Further studies on steroidal glycosides from bulbs, roots and leaves of Allium sativum L. Chem Pharm Bull 1989; 37(10): 2741–2743.

    Article  CAS  Google Scholar 

  199. Abdullah, T. H., D. V. Kirkpatrick and J. Carter. Enhancement of natural killer cell activity in AIDS with garlic. Deutsche Z Onkol 1989; 21(2): 52–53.

    Google Scholar 

  200. Ghannoum, M. A. Inhibition of Candida adhesion to buccal epithelial cells by an aqueous extract of Allium sativum (garlic). J Appl Bacteriol 1990; 68(2): 163–169.

    Article  PubMed  CAS  Google Scholar 

  201. Hussain, S. P., L. N. Jannu and A. R. Rao. Chemopreventive action of garlic on methylcholanthrene-induced carcinogenesis in the uterine cervix of mice. Cancer Lett 1990; 49(2): 175–180.

    Article  PubMed  CAS  Google Scholar 

  202. Mossa, J. S. A study on the crude antidiabetic drugs used in Arabian folk medicine. Int J Crude Drug Res 1985; 23(3): 137–145.

    Google Scholar 

  203. Srivastava, K. G Aqueous extracts of onion, garlic and ginger inhibited platelet aggregation and alter arachidonic acid metabolism. Biomed Biochem Acta 1984; 43(8/9): 5335–5346.

    Google Scholar 

  204. Ueda, Y., M. Sakaguchi, K. Hirayama, R. Miyajima and A. Kimizuka. Characteristic flavor constituents in water extract of garlic. Agr Biol Chem 1990; 54(1): 163–169.

    Article  CAS  Google Scholar 

  205. Shah, A. H., M. Tariq, A. M. Ageel and S. Qureshi. Cytological studies on some plants used in traditional Arab medicine. Fitoterapia 1989; 60(2): 171–173.

    Google Scholar 

  206. Srivastava, K. C. and U. Justesen. Isolation and effects of some garlic components on platelet aggregation and metabolism of arachidonic acid in human blood platelets. Wien Klin Wochenschr 1989; 101(8): 293–299.

    PubMed  CAS  Google Scholar 

  207. Makheja, A. N. and J. M. Bailey. Antiplatelet constituents of garlic and onion. Agents Actions 1990; 29(3/4): 360–363.

    Article  PubMed  CAS  Google Scholar 

  208. Srivastava, K. C. Evidence for the mechanism by which garlic inhibits platelet aggregation. Prostaglandins Leukotrienes Med 1986; 22:313–321.

    Article  CAS  Google Scholar 

  209. Srivastava, K. C. Effects of aqueous extracts of onion, garlic and ginger on platelet aggregation and metabolism of arachidonic acid in the blood vascular system: In vitro study. Prostaglandins Leukotrienes Med 1984; 13(2): 227–235.

    Article  Google Scholar 

  210. Joseph, P. K. and C. S. Sundaresh. Serum urea and enzymes in rat on intragastric administration of garlic oil and garlic extracts. Curr Sci 1989; 58(24): 1409–1410.

    CAS  Google Scholar 

  211. Unnikrishnan, M. C. and R. Kutan. Tumour reducing and anticarcinogenic activity of selected spices. Cancer Lett 1990; 51(1): 85–89.

    Article  PubMed  CAS  Google Scholar 

  212. Lau, B. H. S., F. Lam and R. Wang-Cheng. Effect of an odor modified garlic preparation on blood lipids. Nutr Res 1987; 7:139–149.

    Article  CAS  Google Scholar 

  213. Swanston-Flatt, S. K., C. Day, C. J. Bailey and P. R. Flatt. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990; 33(8): 462–464.

    Article  PubMed  CAS  Google Scholar 

  214. Okuyama, T., K. Fujita, S. Shibata, M. Hoson, T. Kawada, M. Masaki and N. Yamate. Effects of Chinese drugs “Xiebai” and “Dasuan” on human platelet aggregation (Allium bakeri, A. sativum). Planta Med 1989; 55(3): 242–244.

    Article  PubMed  CAS  Google Scholar 

  215. Nakagawa, S., S. Kasuga and H. Matsuura. Prevention of liver damage by aged garlic extract and its components in mice. Phytother Res 1989; 3(2): 50–53.

    Article  CAS  Google Scholar 

  216. Perchellet, J. P, E. M. Perchellet and S. Belman. Inhibition of DMBA-induced mouse skin tumorigenesis by garlic oil and inhibition of two tumor-promotion stages by garlic and onion oils. Nutr Cancer 1990; 14(3/4): 183–193.

    Article  PubMed  CAS  Google Scholar 

  217. Meng, C. L. and K. W. Shyu. Inhibition of experimental carcinogenesis by painting with garlic extract. Nutr Cancer 1990; 14(3/4): 207–217.

    Article  PubMed  CAS  Google Scholar 

  218. Shyu, K. W. and C. L. Meng. The inhibitory effect of oral administration of garlic on experimental carcinogenesis in hamster buccal pouches by DMBA painting. Proc Natl Sci Couc Part B Repub China 1987; 11(2): 137–147.

    CAS  Google Scholar 

  219. Desai, H. G., R. H. Kairo and A. P. Choksi. Effect of ginger and garlic on DNA content of gastric aspirate. Indian J Med Res [B] 1990; 92(2): 139–141.

    CAS  Google Scholar 

  220. Mader, F. H. Treatment of hyperlipidaemia with garlic-powder tablets: Evidence from the German Assocation of General Practitioners’ multicentric placebo-controlled double-blind study. Arzneim-Forsch 1990; 40(10): 1111–1116.

    CAS  Google Scholar 

  221. Rose, K. D., P. D. Croissant, C. F. Parliament and M. B. Levin. Spontaneous spinal epidural hematoma with associated platelet dysfunction from excessive garlic ingestion: a case report. Neurosurgery 1990; 26(5): 880–882.

    Article  PubMed  CAS  Google Scholar 

  222. Suresh, M and R. K. Rai. Cardol: The antifilarial principle from Anacardium occidentale. Curr Sci 1990; 59(9): 477–479.

    CAS  Google Scholar 

  223. Rao, A. R., A. S. Sadhana and H. C. Goel. Inhibition of skin tumors in DMBA-induced complete carcinogenesis system in mice by garlic (Allium sativum). Indian J Exp Biol 1990; 28(5): 405–408.

    PubMed  CAS  Google Scholar 

  224. Miwa, M., Z. L. Kong, K. Shinohara and M. Watanabe. Macrophage stimulating activity of foods. Agr Biol Chem 1990; 54(7): 1863–1866.

    Article  Google Scholar 

  225. Norris, B. C., C. V. Pantoja, L. C. H. Chiang, B. Concha, V. R. Neumann and D. V. Ferrada. Inhibitory effect of garlic (Allium sativum) on sodium transport in isolated toad skin. J Ethno-Pharmacol 1991; 31(3): 309–318.

    CAS  Google Scholar 

  226. Arora, R. B., T. Khanna, M. Imran and D. K. Balani. Effect of lipotab on myocardial infarction induced by isoproterenol. Fitoterapia 1990; 61(4): 356–358.

    Google Scholar 

  227. Sato, A. Studies on anti-tumor activity of crude drugs: I. The effects of aqueous extracts of some crude drugs in short-term screening test. Yakugaku Zasshi 1989; 109(6): 407–423.

    PubMed  CAS  Google Scholar 

  228. Chowdhury, A. K. A, M. Ahsan, S. K. Islam and Z. U. Ahmed. Efficacy of aqueous extract of garlic and allicin in experimental shigellosis in rabbits. Indian J Med Res [A] 1991; 93(1): 33–36.

    CAS  Google Scholar 

  229. Giordano, J. and P. J. Levine. Botanical preparations used in Italian folk medicine: Possible pharmacological and chemical basis of effect. Social Pharmacol 1989; 3(1/2): 83–110.

    Google Scholar 

  230. Caceres, A., B. R. Lopez, M. A. Giron and H. Logemann. Plants used in Guatemala for the treatment of der-matophytic infections: I. Screening for antimycotic activity of 44 plant extracts. J Ethnopharmacol 1991; 31(3): 263–276.

    Article  PubMed  CAS  Google Scholar 

  231. Sunter, W. H. Warfarin and garlic. Pharm J 1991; 246(6640): 722.

    Google Scholar 

  232. Gebhardt, R. Inhibition of cholesterol biosynthesis by a water-soluble garlic extract in primary cultures of rat hepatocytes. Arzneim-Forsch 1991; 41(8): 800–804.

    CAS  Google Scholar 

  233. Scortichini, M. and M. P. Rossi. In vitro activity of some essential oils toward Erwinia amylovora (Burril) Winslow, et al. Acta Phytopathol Entomol Hung 1989; 24(3/4): 421–423.

    Google Scholar 

  234. Parish, R. A., S. McIntire and D. M. Heimbach. Garlic burns: a naturopathic remedy gone awry. Pediatric Emergency Care 1988; 3(4): 258–260.

    Article  Google Scholar 

  235. Aqel, M. B., M. N. Gharaibah and A. S. Salhab. Direct relaxant effects of garlic juice on smooth and cardiac muscles. J Ethnopharmacol 1991; 33(1/2): 13–19.

    Article  PubMed  CAS  Google Scholar 

  236. Kiuchi, F., N. Nakamura, N. Miyashita, S. Nishizawa, Y. Tsuda and K. Kondo. Nematocidal activity of some anthelmintics, traditional medicines and spices by a new assay method using larvae of Toxocara canis. Shoyakugaku Zasshi 1989; 43(4): 279–287.

    Google Scholar 

  237. Mansell, P and J. P. Reckless. Effects on serum lipids, blood pressure, coagulation, platelet aggregation and vasodilation. Brit Med J 1991; 303(6799): 379–380.

    Article  PubMed  CAS  Google Scholar 

  238. Meng, C. L. and K. W. Shyu. Inhibition of experimental carcinogenesis by painting with garlic extract. Nutr Cancer 1990; 14(3/4): 207–217.

    Article  PubMed  CAS  Google Scholar 

  239. Orellana, A., M. E. Kawada, M. N. Morales, L. Vargas and M. Bronfman. Induction of peroxisomal fatty acyl-coenzyme A transferase in primary cultures of rat hepatocytes by garlic extracts. Toxicol Lett 1992; 60(1): 11–17.

    Article  PubMed  CAS  Google Scholar 

  240. Kim, S. H., J. O. Kim, S. H. Lee, K. Y. Park, H. J. Park and H. Y. Chung. An-timutagenic compounds identified from the chloroform fraction of garlic (Allium sativum), Hanguk Yongyang Siklyong Hakhoe Chi 1991; 20(3): 253–259.

    CAS  Google Scholar 

  241. Misra, S. B. and S. N. Dixit. Antifungal spectrum of some plant extracts. Geobios 1977; 4(1): 29–30.

    Google Scholar 

  242. Sharma, V. D., M. S. Sethi, A. Kumar, and J. R. Rarotra. Antibacterial property of Allium sativum, in vivo and in vitro studies. Indian J Exp Biol 1977; 15: 466.

    PubMed  CAS  Google Scholar 

  243. Kazaryan, R. A. and E. V. Goryachenkova. Allinase: Purification and physicochemical properties. Biokhimiya 1978; 43: 1905–1913.

    CAS  Google Scholar 

  244. Tonoda, A. Preparation of ginseng extracts. Patent-Japan Kokai Tokkyo Koho 1983; 58 29,713: 2 pp.

    Google Scholar 

  245. Caporaso, N., S. M. Smith and R. H. K. Eng. Antifungal activity in human urine and serum after ingestion of garlic (Allium sativum). Antimicrob Agents Chemother 1983; 23(5): 700–702.

    Article  PubMed  CAS  Google Scholar 

  246. Sangmahachai, K. Effect of onion and garlic extracts on the growth of certain bacteria. Master Thesis 1978; 88pp.

    Google Scholar 

  247. Wongcharoentham, B. Studies on the effect of garlic extract on the growth of Candida. Undergraduate Special Project Report Fac Med 1978; 35pp.

    Google Scholar 

  248. Mand, J. K., P. P. Gupta, G. L. Soni and R. Singh. Role of garlic (Allium cepa) in the reversal of atherosclerosis in rabbits. Abstr 3rd Congress of the Federation of Asian and Oceanian Biochemists 1983; 79.

    Google Scholar 

  249. Chaiyasothi, T. and V. Rueaksopaa. Antibacterial activity of some medicinal plants. Undergraduate Special Project Report 1975; 109pp.

    Google Scholar 

  250. Malaengpoothong, B. Studies on the antifungal activity of garlic extract. Undergraduate Special Project Report Fac Med 1980; 31pp.

    Google Scholar 

  251. Poopipatpol, A. and U. Siriboonyarit. The effect of garlic water extract on smooth muscle. Undergraduate Spe-cial Project Report 1980; 51pp.

    Google Scholar 

  252. Soytong, K., V. Rakvidhvasastra and T. Sommartya. Effect of some medicinal plants on growth of fungi and potential in plant disease control. lAbstr 11th Conference of Science and Technology 1985; 361.

    Google Scholar 

  253. Anussorn-Nitisara, N. and A. M. Vudthludomlert. Modification of pharmaceutical preparation of garlics. Abstr 10th Conference of Science and Technology 1984; 241–242.

    Google Scholar 

  254. Imwidthaya, S., A. Plangpatanapanichya and P. Thasnakorn. Antifungal activity of garlic extract. Bull Fac Med Tech Mahido Univ 1978; 2(2): 67–77.

    Google Scholar 

  255. Ploddee, A. and R. Palakornkol. Antifungal activity of garlic. Under-graduate Special Project Report 1977; 23pp.

    Google Scholar 

  256. Jain, R. C. and D. B. Konar. Effect of garlic oil in experimental cholesterol atherosclerosis. Atherosclerosis 1978; 29: 125.

    Article  PubMed  CAS  Google Scholar 

  257. Bogin, E. and M. Abrams. The effect of garlic extract on the activity of some enzymes. Food Cosmet Toxicol 1976; 14:417–419.

    Article  PubMed  CAS  Google Scholar 

  258. Suh, M. J. Effects of condiments upon alpha-amylase activity. Hanguk Yongyang Hakhoe Chi 1976; 9: 104.

    CAS  Google Scholar 

  259. Demkevich, L. I. Change in the amino acid composition of garlic leaves in the vegetation period. Izv Vyssh Uchebn Zaved Pisch Tekhnol 1978; 149.

    Google Scholar 

  260. Czajka, P., D. Pharm, J. Field, P. Novak and J. Kunnecke. Accidental aphrodisiac ingestion. J Tenn Med Ass 1978; 71: 747.

    CAS  Google Scholar 

  261. Van Ketel, W. G. and P. DeHann. Occupation eczema from garlic and onion. Contact Dermatitis 1978; 4: 53–54.

    Article  PubMed  Google Scholar 

  262. Ayensu, E. S. Medicinal Plants of the West Indies. Unpublished manuscript 1978; 110pp.

    Google Scholar 

  263. Sharma, K. K., A. L. Sharma, K. K. Dwived and P. K. Sharma. Effect of raw and boiled garlic on blood cholesterol in butter fat lupaemia. Indian J Nutr Diet 1976; 13: 7–10.

    CAS  Google Scholar 

  264. Tyrell, H. ...Or garlic. Lancet 1979; 1294 A.

    Google Scholar 

  265. Slater, N. G. P. ...Or garlic. Lancet 1979; 1294A

    Google Scholar 

  266. Bordia, A. K. and H. K. Joshi. Garlic on fibrinolytic activity in cases on acute myocardial infarction. Part II. J Ass Phys India 1978; 26: 323–326.

    CAS  Google Scholar 

  267. Makheja, A. N., J. Y. Vanderhoek and J. M. Bailey. Inhibition of platelet aggregation and thromboxane synthesis by onion and garlic. Lancet 1979; 781.

    Google Scholar 

  268. Woo, W. S., K. H. Shin and I. C. Kim. The effects of irritating spices on drug metabolizing enzyme activity. Effects on hexobarbital hypnosis in mice. Korean J Pharmacog 1977; 8: 115–119.

    CAS  Google Scholar 

  269. Bhushan, S., S. P. Sharma, S. P. Singh, S. Agrawal, A. Indrayan and P. Seth. Effect of garlic on normal blood cholesterol level. Indian J Physiol Pharmacol 1979; 23: 211–214

    PubMed  CAS  Google Scholar 

  270. Petricic, J., M. Kupinic and B. Lulic. Garlic (Allium sativum L.) antifungal effect of some components of volatile oil. Acta Pharm Jugoslav 1978; 28: 41–43.

    Google Scholar 

  271. Raman, J. S., K. V. Srinivasamurthy, B. Padmarajarao. A compound of Lasuna (garlic) in the prevention and treatment of cardiovascular diseases. J Nat Integrated Med Ass 1978; 20: 225–227.

    Google Scholar 

  272. Bordia, A. K., S. K. Sanadhya, A. S. Rathore and N. Bhu. Essential oil of garlic on blood lipids and fibrinolytic activity in patients of coronary artery disease: Part I.J Ass Phys India 1978; 26:327–331.

    CAS  Google Scholar 

  273. Chang, M. L. W. and M. A. Johnson. Effect of garlic on carbohydrate metabolism and lipid synthesis in rats. J Nutr 1980; 110:931–936.

    PubMed  CAS  Google Scholar 

  274. Sainani, G. S., D. B. Desai, N. H. Gorhe, D. V. Pise and P. G. Sainani. Effect of garlic and onion on important lipid and coagulation parameters in alimentary hyperlipaemia. J Ass Phys India 1979; 27: 57–64.

    CAS  Google Scholar 

  275. Arunachalam, K. Antimicrobial activity of garlic, onion and honey. Geobios 1980; 7(1): 46–47.

    Google Scholar 

  276. Mantis, A. J., P. A. Koidis and P. A. G. Karaioannoglou. Effect of garlic extract on food poisoning bacteria. Lebensm Wiss Technol 1979; 12: 330–332.

    Google Scholar 

  277. Jain, R. C. Effect of alcoholic extract of garlic in atherosclerosis. Amer J Clin Nutr 1978; 31: 1982–1983.

    CAS  Google Scholar 

  278. Tucakov, J. Ethnophytotherapy of diabetes. Srp Arh Celok Lek 1978; 106: 159–173.

    PubMed  CAS  Google Scholar 

  279. Zacharias, N. T., K. L. Sebastian, B. Philip and K. T. Augusti. Hypoglycemic and hypolipidaemic effects of garlic in sucrose-fed rabbits. Indian J Physiol Pharmacol 1980; 24: 151–154.

    PubMed  CAS  Google Scholar 

  280. Makheja, A. N., J. Y. Vanderhoek, R. W. Bryant and J. M. Bailey. Altered arachi-donic acid metabolism in platelets inhibited by onion or garlic extracts. Adv Prostaglandin Thromboxane Res 1980; 6:309–312.

    PubMed  CAS  Google Scholar 

  281. Lang, Y. J. and K. Y. Cheng. Studies on the active principles of garlic. Chung Ts’ao Yao 1981; 12(1): 4–6.

    CAS  Google Scholar 

  282. Ariga, T. and S. Oshiba. Effects of the essential oil components of garlic cloves on rabbit platelet aggregation. Igaku To Seibutsugaku 1981; 102(4): 169–174.

    CAS  Google Scholar 

  283. Ariga, T. and S. Oshiba. Inhibition of human platelet aggregation by garlic oil and related substances. Igaku To Seibutsugaku 1981; 102(4): 175–180.

    CAS  Google Scholar 

  284. Boullin, D. J. Garlic as a platelet inhibitor. Lancet 1981; 776–777.

    Google Scholar 

  285. Osman, S. A. Chemical and biological studies of onion and garlic in an attempt to isolate a hypoglycaemic extract. Abstr 4th Asian Symp Med Plants Spices 1980; 117.

    Google Scholar 

  286. Godhwani, J. L. and J. B. Gupta. Modification of immunological response by garlic, guggal and turmeric: An experimental study in animals. Abstr 13th Annual Conf Indian Pharmacol Soc 1980; Abstr-12.

    Google Scholar 

  287. Kloos, H. Preliminary studies of medicinal plants and plant products in markets of Central Ethiopia. Ethnomedicine 1977; 4(1): 63–104.

    Google Scholar 

  288. Bhat, P. G. and T. N. Pattabiraman. Solubilization and purification of a particulate hexokinase from garlic (Allium sativum) bulbs. Indian J Biochem Biophys 1979; 16: 284–287.

    PubMed  CAS  Google Scholar 

  289. Bordia, A. Effect of garlic on blood lipids in patients with coronary heart disease. Amer J Clin Nutr 1981; 34: 2100–2103.

    PubMed  CAS  Google Scholar 

  290. Gurpratap, S. and K. Raghuvansh. Garlic in dyspepsia (a trial in 30 cases). Antiseptic 1981; 78: 197–200.

    Google Scholar 

  291. Kamanna, V. S. and N. Changrasekhara. Effect of garlic (Allium sativum Linn.) on serum lipoproteins and lipoprotein cholesterol levels in albino rats rendered hypercholesteremic by feeding cholesterol. Lipids 1982; 17(7): 483–488.

    Article  PubMed  CAS  Google Scholar 

  292. Vanderhoek, J. Y., A. N. Makheja and J. M. Bailey. Inhibition of fatty acid oxygenases by onion and garlic oils: Evidence for the mechanism by which these oils inhibit platelet aggregation. Biochem Pharmacol 1980; 29: 3169–3173.

    Article  PubMed  CAS  Google Scholar 

  293. Kumar, C. A., K. K. Saxena, C. Gupta, R. Gopal, R. C. Singh, S. Juneja, R. K. Srivastava and D. N. Prasad. Allium sativum: Effect of three weeks feeding in rats. Indian J Pharmacol 1981; 13: 91.

    Google Scholar 

  294. Amia, V., D. Singh, R. K. Raina and T. R. Sharma. Preliminary clinical evaluation of garlic capsule in chronic rheumatic disorders. Indian J Pharmacol 1981; 13:64.

    Google Scholar 

  295. Kaur, J., S. Goyal, V. Bhasin, V. K. Kulshrestha and D. N. Prasad. Effect of C. mukul, A. sativum and A. cepa on coagulation and fibrinolysis in experimental atherosclerosis. Indian J Pharmacol 1981; 13(3): 90–91.

    Google Scholar 

  296. Dixit, V. P. and S. Joshi. Effects of chronic administration of garlic (Allium sativum Linn.) on testicular function. Indian J Exp Biol 1982; 20: 534–536.

    PubMed  CAS  Google Scholar 

  297. Bolton, S., G. Null and W. M. Troetel. The medical uses of garlic: fact and fiction. Amer Pharm NS 1982; 22(8): 40–43.

    Google Scholar 

  298. Ariga, T. and S. Oshiba. Inhibition of platelet aggregation by garlic oil components: Separation and identification of an effective substance. Igaku No Ayumi 1981; 118:859–862.

    CAS  Google Scholar 

  299. Adamu, I., P. K. Joseph and K. T. Augusti. Hypolipidemic action of onion and garlic unsaturated oils in sucrose-fed rats over a two-month period. Experientia 1982; 38: 899–901.

    Article  PubMed  CAS  Google Scholar 

  300. Prasad, G., V. D. Sharma and A. Kumar. Efficacy of garlic (Allium sativum L.) therapy against experimental dermatophytosis in rabbits. Indian J Med Res 1982; 75: 465–467.

    PubMed  CAS  Google Scholar 

  301. Chi, M. S., E. T. Koh and T. J. Stewart. Effects of garlic on lipid metabolism in rats fed cholesterol or lard. J Nutr 1982; 112:241–248.

    PubMed  CAS  Google Scholar 

  302. Maroli, S. and S. Javale. Garlic (Allium sativum) as a common household remedy. Pediatr Clin India 1982; 17(2): 9–10.

    Google Scholar 

  303. Sainani, G. B., D. P. Bhalode, S. M. Natu, D. V. Pise and R. Kayerkar. Garlic pearls in cases of hyperlipidaemia (A report of a clinical trial). Antiseptic 1982; 79: 201–204.

    Google Scholar 

  304. Das, S. N., A. K. Pramanik, S. K. Mitra and B. N. Mukherjee. Effect of garlic pearls (ranbaxy) on blood cholesterol level in normal dogs. Indian Vet J 1982; 59: 937–938.

    CAS  Google Scholar 

  305. Prakash, A. O., R. B. Gupta and R. Mathur. Effect of oral administration of forty-two indigenous plant extracts on early and late pregnancy in albino rats. Probe 1978; 17(4): 315–323.

    Google Scholar 

  306. Chi, M. S, Effects of garlic products on lipid metabolism in cholesterol-fed rats. Proc Soc Exp Biol Med 1982; 171: 174–178.

    PubMed  CAS  Google Scholar 

  307. Kumar, A. and V. D. Sharma. Inhibitory effect of garlic (Allium sativum) on enterotoxigenic Escherichia coli. Indian J Med Res 1982; 76: 66–70.

    PubMed  Google Scholar 

  308. Bekdairova, K. Z. Caffeic acid — Natural inhibitor of garlic bulb growth. Izv Akad Nauk Kaz SSR 1981; 4: 20–24.

    Google Scholar 

  309. Baldwa, V. S., P. C. Ranka, J. P. Rishi and R. R. Rai. Commiphora mukul (guggul), garlic extract and Clofibrate in hypolipidaemic states. Rajasthan Med J 1981; 20(2): 73–76.

    Google Scholar 

  310. AS310 Godhwani, J. D., J. B. Gupta and A. P. Dadhich. Modification of immunological response by garlic, guggal and turmeric: an experimental study in albino rats. Proc Indian Pharmacol Soc 1980; Abstr 1–2.

    Google Scholar 

  311. Zaman, Q. A. M., H. Banoo, S. Choudhury and A. Khaleque. Effect of garlic oil on serum cholesterol and blood sugar levels in adult human volunteers in Bangladesh. Bangladesh Med J 1981; 10(1): 6–10.

    Google Scholar 

  312. Chutani, S. K. and A. Bordia. The effect of fried versus raw garlic on fibrinolytic activity in man. Atherosclerosis 1981;38:417–421.

    Article  PubMed  CAS  Google Scholar 

  313. Nagda, K. K., S. K. Ganeriwal, K. C. Nagda and A. M. Diwan. Effect of onion and garlic on blood coagulation and fibrinolysis in vitro. Indian J Physiol Pharmacol 1983; 27(2): 141–145.

    PubMed  CAS  Google Scholar 

  314. Lal, S. D. and B. K. Yadav. Folk medicine of Kurukshetra district (Haryana), India. Econ Bot 1983; 37(3): 299–305.

    Article  Google Scholar 

  315. Adesina, S. K. Studies on some plants used as anticonvulsants in Amerindian and African traditional medicine. Fitoterapia 1982; 53: 147–162.

    CAS  Google Scholar 

  316. Tanaka, S., M. Saito and M. Tabata. Bioassay of crude drugs for hair growth promoting activity in mice by a new simple method. Planta Med Suppl 1980; 40: 84–90.

    Article  Google Scholar 

  317. Ross, S. A., N. E. El-Keltawi and S. E. Megalla. Antimicrobial activity of some Egyptian aromatic plants. Fitoterapia 1980; 51: 201–205.

    Google Scholar 

  318. Razzack, H. M. A. The concept of birth control in Unani medical literature. Unpublished manuscript. 1980; 64pp.

    Google Scholar 

  319. Srivastava, K. C., A. D. Perera and H. O. Saridakis. Bacteriostatic effects of garlic sap on Gram negative pathogenic bacteria — An in vitro study. Lebensm Wiss Technol 1982; 15(2): 74–76.

    Google Scholar 

  320. Foushee, D. B., J. Ruffin and U. Banerjee. Garlic as a natural agent for the treatment of hypertension: A preliminary report. Cytobios 1982; 34: 145–152.

    PubMed  CAS  Google Scholar 

  321. Yang, K. Y. and H. S. Shin. Lipids and fatty acid composition of garlic (Allium sativum Linnaeus). Hanguk Sikp’um Kwahakhoe Chi 1982; 14(4): 388–393.

    CAS  Google Scholar 

  322. Qureshi, A. A., N. Abuirmeileh, Z. Z. Din, C. E. Elson and W. C. Burger. Inhibition of cholesterol and fatty acid biosynthesis in liver enzymes and chicken hepatocytes by polar fractions of garlic. Lipids 1983; 18(5): 343–348.

    Article  PubMed  CAS  Google Scholar 

  323. Rakhimbaev, I. R. and R. V. Ol’Shanskaya. Preliminary identification of natural gibberellins of garlic. Izv Akad Nauk Kaz SSR Ser Biol 1981; 2: 17–22.

    Google Scholar 

  324. Elnima, E. I., S. A. Ahmed, A. G. Mekkawi and J. S. Mossa. The antimicrobial activity of garlic and onion extracts. Pharmazie 1983; 38(11): 747–748.

    PubMed  CAS  Google Scholar 

  325. Arime, M. and M. Deki. Components of sugars in garlic. Kanzei Chuo Bunsekishoho 1983; 23: 89–93.

    CAS  Google Scholar 

  326. Naito, S., N. Yamaguchi and Y. Yokoo. Studies on natural antioxidants: III. Fractionation of antioxidant activity from garlic extract. Nippon Shokuhin Kogyo Gakkaishi 1981; 28(9): 465–470.

    Article  CAS  Google Scholar 

  327. Kominato, Y., S. Nishimura and K. Takeyama. Studies on biological active component in garlic (Allium scorodo-prasm L. or Allium sativum): II. Thia-min-retaining effects of scordinin A, B mixture and antibacterial activities of the scordinin decomposition product. Oyo Yakuri 1976; 12: 571–577.

    CAS  Google Scholar 

  328. Stauffer, M. Germanium, a constituent in various medicinal plants. Erfahrungsheilkunde 1980; 29: 646–647.

    Google Scholar 

  329. Abraham, S. K. and P. C. Kesavan. Genotoxicity of garlic, turmeric and asafoetida in mice. Mutat Res 1984; 136(1): 85–88.

    Article  PubMed  CAS  Google Scholar 

  330. Bordia, A. Effect of garlic on human platelet aggregation in vitro. Atherosclerosis 1978; 30(4): 355–360.

    Article  PubMed  CAS  Google Scholar 

  331. Sharma, K. K. and S. P. Sharma. Effect of onion and garlic on serum cholesterol in normal subjects. Mediscope 1979; 22(7): 134–136.

    CAS  Google Scholar 

  332. Jain, R. C. and C. R. Vyas. Onion and garlic in atherosclerotic heart disease. Medikon 1977; 6(5): 12–14.

    CAS  Google Scholar 

  333. Castro, R. A., S. Cabrera, M. R. Cruz, E. Ledezma and M. K. Jain. Effects of garlic extract and of three pure components isolated from it on human platelet aggregation, arachidonate metabolism, release reaction and platelet ultrastructure. Thromb Res 1983; 32(2): 155–169.

    Article  Google Scholar 

  334. Conner, D. E. and L. R. Beuchat. Effects of essential oils from plants on growth of food spoilage yeasts. J Food Sci 1984; 49(2): 429–434.

    Article  Google Scholar 

  335. Lechner-Knecht, S. Sacred healing plants in Nepal. Dtsch Apoth Ztg 1982; 122:2122–2129.

    Google Scholar 

  336. Ungsurungsie, M., O. Suthienkul and C. Paovalo. Mutagenicity screening of popular Thai spices. Food Chem Toxicol 1982; 20: 527–530.

    Article  PubMed  CAS  Google Scholar 

  337. Martinez, M. A. Medicinal plants used in a Totonac community of the Sierra Norte de Puebla: Tuzamapan de Galeana, Puebla, Mexico. J Ethnopharmacol 1984; 11(2): 203–221.

    Article  Google Scholar 

  338. Gaffen, J. D., I. A. Tavares and A. Bennett. The effect of garlic extracts on contractions of rat gastric fundus and human platelet aggregation. J Pharm Pharmacol 1984; 36(4): 272–274.

    Article  PubMed  CAS  Google Scholar 

  339. Chauhan, L. S., J. Garg, H. K. Bedi, R. C. Gupta, B. S. Bomb and M. P. Agarwal. Effect of onion, garlic and Clofibrate on coagulation and fibrinolytic activity of blood in cholesterolfed rabbits. Indian Med J 1982; 76(10): 126–127.

    Google Scholar 

  340. Sodimu, O., P. K. Joseph and K. T. Augusti. Certain biochemical effects of garlic oil on rats maintained on high fat-high cholesterol diet. Experientia 1984; 40(1): 78–79.

    Article  PubMed  CAS  Google Scholar 

  341. Kamanna, V. S. and N. Changrasekhara. Hypocholestermic activity of different fractions of garlic. Indian J Med Res 1984; 79(4): 580–583.

    PubMed  CAS  Google Scholar 

  342. Choy, Y. M., T. T. Kwok, K. P. Fung and C. Y. Lee. Effect of garlic, Chinese medicinal drugs and amino acids on growth of Erlich ascites tumor cells in mice. Amer J Chin Med 1983; 11(1/4) 69–73.

    Article  CAS  Google Scholar 

  343. Boukef, K, H. R. Souissi and G. Balansard. Contribution to the study on plants used in traditional medicine in Tunisia. Plant Med Phytother 1982; 16(4): 260–279.

    Google Scholar 

  344. Kim, S. K., E. S. Bae and C. W. Cha. A study on the effect of garlic on the toxicity of cadmium in rats. Koryo Taehakkyo Uikwa Taehak Nonmunjip 1984; 21(1): 65–76.

    CAS  Google Scholar 

  345. Hsu, B. Recent progress in antineoplastic drug research in China (review). Cancer Research in the People’s Republic of China and the United States of America — Epide-miology, Causation and Approaches to Therapy 1980; 235–250.

    Google Scholar 

  346. Cosminsky, S. Anthropology of Human Birth, Chapter 12. 1982: 233–252.

    Google Scholar 

  347. Rattanapanone, V. Antithiamin factor in fruits, mushrooms and spices. Chiang Mai Med Bull 1979; 18: 9–16.

    CAS  Google Scholar 

  348. Kanezawa, A., S. Nakagawa, H. Sumiyoshi, K. Masamoto, H. Harada, S. Nakagami, S. Date, A. Yokota, M. Nishikawa and T. Fuwa. General toxicity testing of a garlic extract preparation containing vitamins (kyoleopin). Oyo Yakuri 1984; 27(5): 909–929.

    CAS  Google Scholar 

  349. Tongia, S. K. Effects of intravenous garlic juice (Allium sativum) on rat electrocardiogram. Indian J Physiol Pharmacol 1984; 28(3): 250–252.

    PubMed  CAS  Google Scholar 

  350. Singh, K. V. and R. K. Pathak. Effect of leaves extracts of some higher plants on spore germination of Ustilago maydes and 17. nuda. Fitoterapia 1984; 55(5): 318–320.

    Google Scholar 

  351. Singh, K. V. and N. P. Shukla. Activity on multiple resistant bacteria of garlic (Allium sativum) extract. Fitoterapia 1984; 55(5): 313–315.

    Google Scholar 

  352. Ojewole, J. A. O., A. D. Adekile and O. O. Odebiyi. Pharmacological studies on a Nigerian herbal preparation: 1. Cardiovascular actions of cow’s urine concoction (CUC) and its individual components. Int J Crude Drug Res 1982; 20: 71–85.

    Google Scholar 

  353. Hemadri, K. and S. Sasibhushana Rao. Antifertility, abortifacient and fertility promoting drugs from Dandakaranya. Ancient Sci Life 1983; 3(2): 103–107.

    CAS  Google Scholar 

  354. Bobboi, A., K. T. Augusti and P. K. Joseph. Hypolipidemic effects of onion oil and garlic oil in ethanol-fed rats. Indian J Biochem Biophys 1984; 21(3): 211–213.

    PubMed  CAS  Google Scholar 

  355. Sarkar, A. R. and M. K. De. Some observations on the role of garlic in the treatment of experimental hyperlipidemia. Cal Med J 1983; 80(11/12): 157–161.

    Google Scholar 

  356. Prasad, G., V. D. Sharma, V. N. Rao and A. Kumar. Efficacy of garlic (Allium sativum) treatment against dermatophytosis in man and animals. Indian Vet Med J 1983; 7(3): 161–163.

    Google Scholar 

  357. AS357 Anon. More praise for onions and garlic. Food Chem Toxicol 1984; 22(11): 918.

    Google Scholar 

  358. Browner, C. H. Plants used for reproductive health in Oaxaca, Mexico. Econ Bot 1985; 39(4): 482–504.

    Article  PubMed  CAS  Google Scholar 

  359. Bobboi, A., K. T. Augusti and P. K. Joseph. Hypolipidemic effects of onion oil and garlic oil in ethanol-fed rats. Indian J Biochem Biophys 1984; 21(3): 211–213.

    PubMed  CAS  Google Scholar 

  360. Said, M. Potential of herbal medicines in modern medical therapy. Ancient Sci Life 1984; 4(1): 36–47.

    CAS  Google Scholar 

  361. Woo, W. S., E. B. Lee, K. H. Shin, S. S. Kang and H. J. Chi. A review of research on plants for fertility regulation in Korea. Korean J Pharmacog 1981; 12(3): 153–170.

    Google Scholar 

  362. Mossa, J. S. A study on the crude antidiabetic drugs used in Arabian folk medicine. Int J Crude Drug Res 1985; 23(3): 137–145.

    Google Scholar 

  363. Lee, H. S., E. S. Bae and C. W. Cha. The effect of garlic on pathological damages of testis due to cadmium poisoning. Koryo Taehakkyo Uikwa Taehak Nonmunjip 1984; 21(3): 39–47.

    CAS  Google Scholar 

  364. Park, J. S. and C. W. Cha. A study on the effect of garlic on the toxicity of phenyl mercuric acetate in rats. Koryo Taehakkyo Uikwa Taehak Nonmunjip 1984; 21(3): 49–58.

    CAS  Google Scholar 

  365. Afzal, M., R. A. H. Hassan, A. A. El-Kazimi and R. M. A. Fattah. Allium sativum in the control of atherosclerosis. Agr Biol Chem 1985; 49(4): 1187–1188.

    Article  CAS  Google Scholar 

  366. Singh, Y. N. Traditional medicine in Fiji: Some herbal folk cures used by Fiji Indians. J Ethnopharmacol 1986; 15(1): 57–88.

    Article  PubMed  CAS  Google Scholar 

  367. Liu, J., X. Lin, C. Li, X. Lin and S. Peng. The blocking effect of garlic on dimeth-ylnitrosamine formation mediated by Fusarium monoliforme. Shandong Yixueyuan Xuebao 1985; 23(2): 31–34.

    CAS  Google Scholar 

  368. Inouye, S., H. Goi, K. Miyauchi, S. Muraki, M. Ogihara and Y. Iwanami. Inhibitory effect of volatile constituents of plants on the proliferation of bacteria — antibacterial activity of plant volatiles. J Antibact Antifung Agents 1983; 11(11); 609–615.

    CAS  Google Scholar 

  369. Hikino, H., M. Tohkin, Y. Kiso, T. Namiki, S. Nishimura and K. Takeyama. Antihepatotoxic actions of Allium sativum bulbs. Planta Med 1986; 3: 163–168.

    Article  PubMed  Google Scholar 

  370. Kanezawa, A., S. Nakagawa, H. Sumiyoshi, K. Masamoto, H. Harada, S. Nakagami, S. Date, A. Yokota, M. Nishikawa and T. Fuwa. General toxicity tests of garlic extract preparation-contained vitamins (kyoleopin). Pharmacometrics 1984; 27(5): 909–929.

    CAS  Google Scholar 

  371. Nakagawa, S., H. Sumiyoshi, K. Masamoto, A. Kanezawa, H. Harada, S. Nakagami, S. Date, A. Yokota, M. Nishikawa and T. Fuwa. Acute and subacute toxicity tests of a ginseng and garlic preparation containing vitamin B-1 (Leopin-five). Pharmacometrics 1984; 27(6): 1133–1150.

    Google Scholar 

  372. Mandai, S. and D. K. Choudhuri. Cholesterol metabolism in Lohita grandis gray (Hemiptera: Pyrrhocoridae: Insecta): Effect of corpora allatectomy and garlic extract. Curr Sci 1982; 51(7): 367–369.

    Google Scholar 

  373. Singh, V., A. Kumar and S. P. Singh. Effect of normal saline, potassium permanganate and garlic extract on healing of contaminated wound in buffalo calves. Indian J Anim Sci 1984; 54(1): 41–45.

    Google Scholar 

  374. Singh, K. V. and S. K. Deshmukh. Volatile consituents from members of Liliaceae and spore germination of Microsporum gypseum complexes. Fitoterapia 1984; 55(5): 297–299.

    CAS  Google Scholar 

  375. Lee, D. G., J. G. Min and C. W. Cha. A study on the effect of garlic in the inhibitory action of cadmium on aLAD activities in human blood in vitro. Koryo Taehakkyo Uikwa Taehak Nonmunjip 1985; 22(1): 135–141.

    CAS  Google Scholar 

  376. Khan, M. R. and N. Mahmood. A study of lipase activity of garlic. J Nat Sci Math 1984; 24(1): 75–82.

    CAS  Google Scholar 

  377. Luley, C., W. Lehmann-Leo, B. Moller, T. Martin and W. Schwartzkopff. Lack of efficacy of dried garlic in patients with hyperlipoproteinemia. Arzneim-Forsch 1986; 36(4): 766–768.

    CAS  Google Scholar 

  378. Huh, K., J. M. Park and S. I. L. Lee. Effect of garlic on the hepatic glutathione s-transferase and glutathione peroxidase activity in rat. Arch Pharm Res 1985; 8(4): 197–203.

    Article  Google Scholar 

  379. Farva, D., I. A. Goji, P. K. Joseph and K. T. Augusti. Effects of garlic oil on streptozotocin-diabetic rats maintained on normal and high-fat diets. Indian J Biochem Biophys 1986; 23: 24–27.

    PubMed  CAS  Google Scholar 

  380. Morita, K., M. Hara and T. Kada. Studies on natural desmutagens: screening for vegetable and fruit factors active in inactivation of mutagenic pyrolysis products from amino acids. Agr Biol Chem 1978; 42(6): 1235–1238.

    Article  CAS  Google Scholar 

  381. Tsai, Y., L. L. Cole, L. E. Davis, S. J. Lockwood, V. Simmons, G. C. Wild. Antiviral properties of garlic: In vitro effects on Influenza B, Herpes simplex and Coxsackie viruses. Planta Med 1985; 5: 460–461.

    Article  PubMed  Google Scholar 

  382. Alkiewicz, J. and B. Dabrowski. Investigations of application of a lyophilized extract from garlic (Allium sativum L.) in aerosol therapy of respiratory tract diseases in children. Herba Pol 1982; 28(3/4): 195–204.

    Google Scholar 

  383. Guerin, J. C. and H. P. Reveillere. Antifungal activity of plant extracts used in therapy: I. Study of 41 plant extracts against 9 fungi species. Ann Pharm Fr 1984; 42(6): 552–559.

    Google Scholar 

  384. Hwang, J., E. S. Bae and C. W. Cha. A study on the protective effect of Korean garlic on the albino rat, chronically exposed to methylmercury. Koryo Taehakkyo Uikwa Taehak Nonmunjip 1986; 23(1): 121–130.

    CAS  Google Scholar 

  385. Sharma, C. P. and N. V. Nirmala. Effects of garlic extract and of three pure components isolated from it on human platelet aggregation, arachidonate metabolism, release reaction and platelet ultra-structure — Comments. Thromb Res 1985; 37(3): 489–490.

    Article  PubMed  CAS  Google Scholar 

  386. Singhvi, S., K. C. Joshi, S. Hiran, S. Bhandari and L. K. Tambi. Effect of onion and garlic on blood lipids. Rajasthan Med J 1984; 23(1): 3–6.

    Google Scholar 

  387. Kiviranta, J, T. Seppanen, H. Karppanen, H. Huovinen and R. Hiltunen. Effects of onion and garlic extracts of spontaneously hypertonic rats. Pharm Weekbl (Sci Ed) 1987; 9(4): 237.

    Google Scholar 

  388. Papageorgion, C., J. P. Corbet, F. M. Brandao, M. Pecegueiro and C. Benezia. Allergic contact dermatitis to garlic (Allium sativum L.): Identification of the allergens — the role of monodisulphides and trisulphides present in garlic. Arch Dermatol Res 1983; 275(4): 229–234.

    Google Scholar 

  389. Weniger, B., M. Rouzier, R. Daguilh, D. Henrys, J. H. Henrys and R. Anton. Popular medicine of the Central Plateau of Haiti: 2. Ethnopharmacological inventory. J Ethnopharmacol 1986; 17(1): 13–30.

    Article  PubMed  CAS  Google Scholar 

  390. Grainge, M., L. Berger and S. Ahmed. Effect of extracts of Artabotrys uncinatus and Allium sativum on Xanthomonas campestris pv. Oryzae. Curr Sci 1985; 54(2): 90.

    Google Scholar 

  391. Ikpeazu, O. V., K. T. Agusti and P. K. Joseph. Hypolipidemic effect of garlic extracts mixed with 3% ethanol in rats fed sucrose high-fat diet. Indian J Biochem Biophys 1987; 24(4): 252–253.

    PubMed  CAS  Google Scholar 

  392. Mirhadi, S. A. and S. Singh. Effect of garlic extract on in vitro uptake of CA2+ and H2PO4 by matrix of sheep aorta. Indian J Exp Biol 1987; 25: 22–23.

    PubMed  CAS  Google Scholar 

  393. Chi, M. S., E. T. Koh and T. J. Stewart. Effects of garlic on lipid metabolism in rats fed cholesterol or lard. J Nutr 1982; 112(2): 241–248.

    PubMed  CAS  Google Scholar 

  394. Abbruzzese, M. R., E. C. Delaha and V. F. Garagusi. Absence of antimyco-bacterial synergism between garlic extract and antituberculosis drugs. Diagn Microbiol Infect Dis 1987; 8(2): 79–85.

    Article  PubMed  CAS  Google Scholar 

  395. Hirao, Y., I. Sumioka, S. Nakagami, M. Yamamoto, S. Hatono, S. Yoshida, T. Fuwa and S. Nakagawa. Activation of immunoresponder cells by the protein fraction from aged garlic extract. Phytother Res 1987; 1(4): 161–164.

    Article  CAS  Google Scholar 

  396. Kamboj, V. P. A review of Indian medicinal plants with interceptive activity. Indian J Med Res 1988; 4: 336–355.

    Google Scholar 

  397. Plengvidhya, C., S. Chinayon, S. Sitprija, S. Pasatrat and M. Tankeyoon. Effects of spray-dried garlic preparation of primary hyperlipo-proteinemia. J Med Ass Thailand 1988; 71(5): 248–252.

    CAS  Google Scholar 

  398. El-Keltawi, N. E. M., S. E. Megalla and S. A. Ross. Antimicrobial activity of some Egyptian aromatic plants. Herba Pol 1980; 26(4): 245–250.

    Google Scholar 

  399. Iwanami, Y. Inhibiting effects of volatile constituents of plants on pollen growth. Experientia 1981; 37(12): 1280–1281.

    Article  Google Scholar 

  400. Conner, D. E. and L. R. Beuchat. Inhibitory effects of plant oleoresins on yeast. Interact Food Proc Int IUMS-ICFMH 12th Sym 1984; 447–451.

    Google Scholar 

  401. Gupta, P. P., P. Khetrapal and C. L. Ghai. Effect of garlic on serum cholesterol and electrocardiogram of rabbit consuming normal diet. Indian J Med Sci 1987; 41(1): 6–11.

    PubMed  CAS  Google Scholar 

  402. Nes, I. F., R. Skjelkvale, O. Olsvik and B. P. Berdal. The effect of natural spices and oleoresins on Lactobacillus plantarum and Staphylococcus aureus. Microb Assoc Interact Food Proc Int IUMS-ICFMH 12th Sym 1984; 435–440.

    Google Scholar 

  403. Koshimizu, K., H. Ohigashi, H. Tokuda, A. Kondo and K. Yamaguchi. Screening of edible plants against possible anti-tumor promoting activity. Cancer Lett 1988; 39(3); 247–257.

    Article  PubMed  CAS  Google Scholar 

  404. Ramirez, V. R., L. J. Mostacero, A. E. Garcia, C. F. Mejia, P. F. Pelaez, C. D. Medina and C. H. Miranda. Vegetales Empleados en Medicina Tradicional Norperuana. Banco Agrario del Peru and NACL Univ Trujillo 1988; 54pp.

    Google Scholar 

  405. Kagawa, K., H. Matsutaka, Y. Yamaguchi and C. Fukuhama. Garlic extract inhibits the enhanced peroxidation and production of lipids in carbon tetrachloride-induced liver injury. Jap J Pharmacol 1986; 42(1): 19–26.

    Article  PubMed  CAS  Google Scholar 

  406. Caceres, A., L. M. Giron, S. R. Alvarado and M. F. Torres. Screening of antimicrobial activity of plants popularly used in Guatemala for the treatment of dermatomucosal diseases. J Ethnopharmacol 1987; 20(3): 223–237.

    Article  PubMed  CAS  Google Scholar 

  407. Nityanand, S. and N. K. Kappor. Effect of hypocholesterolemic agents of plant origin on catecholamine biosynthesis in normal and cholesterol-fed rabbits. J Biosci 1984; 6(3): 277–282.

    Article  Google Scholar 

  408. Singhvi, S., K. C. Joshi, S. Hiran, S. Bhandari and L. K. Tambi. Effect of onion and garlic on blood lipids. Rajasthan Med J 1984; 23(1): 3–6.

    Google Scholar 

  409. Shah, S. A. and S. B. Vohora. Boron enhances anti-arthritic effects of garlic oil. Fitoterapia 1990; 61(2): 121–126.

    CAS  Google Scholar 

  410. Lau, B. H. S, P. P. Tadi and J. M. Tosk. Allium sativum (garlic) and cancer prevention. Nutr Res 1990; 10(8): 937–948.

    Article  Google Scholar 

  411. Tariq, V. N. and A. C. Magee. Effect of volatiles from garlic bulb extract on Fusarium oxysporum F. sp. Lycopersici. Mycol Res 1990; 94(5): 617–620.

    Article  Google Scholar 

  412. Giron, L. M., G. A. Aguilar, A. Caceres and G. L. Arroyo. Anticandidal activity of plants used for the treatment of vaginitis in Guatemala and clinical trial of a Solanum nigrescens preparation. J Ethnopharmacol 1988; 22(3): 307–313.

    Article  PubMed  CAS  Google Scholar 

  413. Belman, S., A. Sellakumar, M. C. Bosland, K. Savarese and R. D. Estensen. Papilloma and carcinoma production in DMBA-initiated, onion oil-promoted mouse skin. Nutr Cancer 1990; 14(2): 141–148.

    Article  PubMed  CAS  Google Scholar 

  414. Kaplan, B., M. Schaewach-Millet and S. Yorav. Factitial dermatitis induced by application of garlic. Int J Dermatol 1990; 29(1): 75–76.

    Article  PubMed  CAS  Google Scholar 

  415. Guerin, J. C. and H. P. Reveillere. Antifungal activity of plant extracts used in therapy: I. Study of 41 plant extracts against 9 fungi species. Ann Pharm Fr 1984; 42(6): 553–559.

    PubMed  CAS  Google Scholar 

  416. Tadi, P. P., R. W. Teel and B. H. S. Lau. Organosulfur compounds of garlic modulate mutagenesis, metabolism and DNA binding of anatoxin B1. Nutr Cancer 1991; 15(2): 87–95.

    Article  PubMed  CAS  Google Scholar 

  417. Lee, T. Y. and T. H. Lam. Contact dermatitis due to topical treatment with garlic in Hong Kong. Contact Dermatitis 1991; 24(3): 193–196.

    Article  PubMed  CAS  Google Scholar 

  418. Unnikrishnan, M. C., K. K. Soudamini and R. Kuttan. Chemoprotection of garlic extract toward cyclophosphamide toxicity in mice. Nutr Cancer 1990; 13(3): 201–207.

    Article  PubMed  CAS  Google Scholar 

  419. Pantoja, C. V., L. C. Chiange, B. C. Norris and J. B. Concha. Diuretic, natriuretic and hypotensive effects produced by Allium sativum (garlic) in anaesthetized dogs. J Ethnopharmacol 1991; 31(3): 325–331.

    Article  PubMed  CAS  Google Scholar 

  420. Kiesewetter, H., F. Jung, G. Pindur, E. M. Jung, C. Mrowietz and E. Wenzel. Effect of garlic on thrombocyte aggregation, microcirculation and other risk factors. I J Clin Pharmcol Ther Tox 1991; 29(4): 151–155.

    CAS  Google Scholar 

  421. Hughes, B. G. and L. D. Lawson. Antimicrobial effects of Allium sativum L. (garlic), Allium ampeloprasum L. (elephant garlic), Allium cepa L. (onion), garlic compounds and commercial garlic supplement products. Phytother Res 1991; 5(4): 154–158.

    Article  CAS  Google Scholar 

  422. Kourounakis, P. N. and E. A. Rekka. Effect on active oxygen species of alliin and Allium sativum (garlic) powder. Res Commun Chem Pathol Pharmacol 1991; 74(2): 249–252.

    PubMed  CAS  Google Scholar 

  423. Mirhadi, S. A., S. Singh and P. P. Gupta. Effect of garlic supplementation of cholesterol-rich diet on development of atherosclerosis in rabbits. Indian J Exp Biol 1991; 29(2): 162–168.

    PubMed  CAS  Google Scholar 

  424. Jung, E. M., F. Jung, C. Mrowietz, H. Kiesewetter, G. Pindur and E. Wenzel. Influence of garlic powder on cutaneous microcirculation. Arzneinv Forsch 1991; 41(6): 626–630.

    CAS  Google Scholar 

  425. Brosche, T. and D. Platt. Garlic. Brit Med J 1991; 303(6805): 785.

    Article  CAS  Google Scholar 

  426. Uda, N. Extraction of eruboside B from plants as an inhibitor of carcinogens. Patent- Japan Kokai Tokkyo Koho 1990; 02 243, 631: 4 pp.

    Google Scholar 

  427. Deboer, L. W. V. and J. D. Folts. Garlic extract prevents acute platelet thrombus formation in stenosed canine coronary arteries. Amer Heart J 1989; 117(4): 973–975.

    Article  PubMed  CAS  Google Scholar 

  428. Batistic, M. A. Thin-layer chromatographic characterization of preparation from Allium sativum L. Rev Inst Adolfo Lutz 1989; 49(1): 5–10.

    Google Scholar 

  429. Ali, M., M. Thomson, M. A. Alnaqeeb, J. M. Ai-Hassan, S. H. Khater and S. A. Gomes. Antithrombotic activity of garlic: Its inhibition of the synthesis of thromboxane-B2 during infusion of arachidonic acid and collagen in rabbits. Prostaglandins Leukotrienes Essent Fatty Acids 1990; 41(2): 95–99.

    Article  CAS  Google Scholar 

  430. Koch, H. P., W. Jager, J. Hysek and B. Korpert. Garlic and onion extracts: In vitro inhibition of adenosine deaminase. Phytother Res 1992; 6(1): 50–52.

    Article  Google Scholar 

  431. Oelkers, B., H. Diehl and H. Liebig. In vitro inhibition of cytochrome P-450 reductases from pig liver microsomes by garlic extracts. Arzneim-Forsch 1992; 42(2): 136–139.

    CAS  Google Scholar 

  432. Al-Bekairi, A. M., A. H. Shah and S. Qureshi. Effect of Allium sativum on epididymal spermatozoa, estradiol-treated mice and general toxicity. J Ethnopharmacol 1990; 29(2): 117–125.

    Article  PubMed  CAS  Google Scholar 

  433. Sendl, A., G. Elbl, B. Steinke, K. Redl, W. Breu and H. Wagner. Comparative pharmacological inverstigations of Allium ursinum and Allium sativum. Planta Med 1992; 58(1): 1–7.

    Article  PubMed  CAS  Google Scholar 

  434. Lawson, L. D., D. K. Ransom and B. G. Hughes. Inhibition of whole blood platelet-aggregation by compounds in garlic clove extracts and commercial garlic products. Thrombosis Research 1992; 65(2): 141–156.

    Article  PubMed  CAS  Google Scholar 

  435. Panthong, A., D. Kanjanapothi and W. C. Taylor. Ethnobotanical review of medicinal plants from Thai traditional books: Part 1. Plants with antiinflammatory, antiasthmatic and antihypertensive properties. J Ethnopharmacol 1986; 18(3): 213–228.

    Article  PubMed  CAS  Google Scholar 

  436. Lokar, L. C. and L. Poldini. Herbal remedies in the traditional medicine of the Venezia Giulia region (Northeast Italy). J Ethnopharmacol 1988; 22(3): 231–239.

    Article  PubMed  CAS  Google Scholar 

  437. Mukerji, B. and S. K. Gupta. Indigenous drugs in experimental tuberculosis. Chemotherapy Proc Symposium Lucknow 1959; 90.

    Google Scholar 

  438. Pennington, C. W. Medicinal plants utilized by the Pima Montanes of Chihuahua. Amer Indigena 1973; 33: 213–232.

    Google Scholar 

  439. Prakash, A. O. and R. Mathur. Screening of Indian plants for antifertility activity. Indian J Exp Biol 1976; 14: 623–626.

    PubMed  CAS  Google Scholar 

  440. AS439 Bickoff, E. M. Estrogen-like substances in plants. Physiology of Reproduction 1963; 93–118.

    Google Scholar 

  441. Dragendorff, G. Die Heilpflanzen der Verschiedenen Volker und Zeiten, F. Enke, Stuttgart 1898; 885pp.

    Google Scholar 

  442. Ueki, H., M. Kaibara, M. Sakagawa and S. Hayashi. Antitumor activity of plant consituents I. Yakugaku Zasshi 1961; 81: 1641–1644.

    PubMed  CAS  Google Scholar 

  443. Appleton, H. A. and M. R. Tansey. Inhibition of growth of zoopathogenic fungi by garlic extract. Mycologia 1975; 67: 882–885.

    Article  PubMed  CAS  Google Scholar 

  444. Tokin, I. B. The effect of phytonocides on spermatozoa and spermatogenesis in mammals. Dokl Akad Nauk SSSR 1953; 93: 567–568.

    PubMed  CAS  Google Scholar 

  445. Lopez Sotomayor, M. A. Antagonism of Allium sativum and procaine in the uterus. Arch Inst Farmacol Exp 1958; 10: 27–33.

    Google Scholar 

  446. Velasquez, B. L., P. S. Garcia, C. D. Mijan and A. O. Hernando. Vascular effect of garlic extract: its mechanism of action. Arch Inst Farmacol Exp 1958; 10: 15–22.

    CAS  Google Scholar 

  447. Lorenzo Velazquez, B. and J. M. Orellana Rodriguez. Action of garlic, corticotropin and cortisone on vaginal estrus. Arch Inst Farmacol Exp 1955; 8: 5–9.

    CAS  Google Scholar 

  448. Lorezo Velazquez, B. and J. M. Orellana Rodriguez. Elimination of 17-Keto steroids following the action of garlic extract. Arch Inst Farmacol Exp 1955; 8: 10–22.

    Google Scholar 

  449. Vasil’ev, A. A. Therapy of ducks and geese in hymenolepidosis. Veterinariya 1957; 34(1): 43–46.

    Google Scholar 

  450. AS449 Chopra, R. N. Indigenous Drugs of India, Their Medical and Economic Aspects. The Art Press 1933; 550pp.

    Google Scholar 

  451. Sanfilippo, G. and G. Ottaviano. Pharmacological investigations on Allium sativum. I. General action II. Action on the arterial pressure and on the respiration. Boll Soc Ital Biol Sper 1944; 19: 156–158.

    Google Scholar 

  452. Cavallito, C. J. and J. H. Bailey. Allicin, the antibacterial principle of Allium sativum: 1. Isolation, physical properties and antibacterial effects. J Amer Chem Soc 1944; 66: 1950–1951.

    Article  CAS  Google Scholar 

  453. Damrau, F. and E. A. Ferguson. The modus operandi of carminatives: the therapeutic value of garlic in functional gastrointestinal disorders. Rev Gastroenterol 1949; 16: 411–419.

    PubMed  CAS  Google Scholar 

  454. Filippov, V. and M. Ii’ina. The state of biotin in plant material. Dokl Akad Nauk SSSR 1954; 95: 1267–1270.

    PubMed  CAS  Google Scholar 

  455. Lehmann, F. A. Investigation of the pharmacology of Allium sativum (garlic). Arch Exp Pathol Pharmakol 1930; 147: 245–264.

    Article  CAS  Google Scholar 

  456. Keck, K. and O. Hoffmann-Ostenhof. Constituents of garlic and their effects: III. The mutagenic action of garlic extracts. Monatsh 1956; 87: 240–242.

    Article  CAS  Google Scholar 

  457. Thiersch, H. The effect of garlic on the experimental cholesterol arteriosclerosis of rabbits. Z Ges Exp Med 1936; 99: 473–477.

    Article  CAS  Google Scholar 

  458. Rico, J. T. Antihelminthic properties of Allium sativum. Compt Rend Soc Biol 1926; 95: 1597–1599.

    CAS  Google Scholar 

  459. Tempel, K. H. Effect of garlic on experimental cholesterol atherosclerosis in rabbits. Med Ernaehr 1962; 3(9); 197–199.

    CAS  Google Scholar 

  460. Umbert de Torrescasana, E. Experimental studies of the pharmacology of the active principles of Allium sativum (garlic). Rev Espan Fisiol 1946; 2: 6–31.

    Google Scholar 

  461. AS460 Kominato, K. Scordinines A and B from garlic. Patent- Japan 1970; 70 12,876:4pp.

    Google Scholar 

  462. AS461 Kominato, H. Scordine from garlic. Patent Japan 1968; 71 14,918: 3pp.

    Google Scholar 

  463. AS462 Kominato, K and M. Kominato. Separation of scordinine A-1, A-2, and B from garlic. Patent-Japan 1972; 72 15,115:4pp.

    Google Scholar 

  464. Tansy, M. R. and J. A. Appleton. Inhibition of fungal growth by garlic extract. Mycologia 1975; 67: 409–413.

    Article  Google Scholar 

  465. Rodriguez, J. M. O. Elimination of 17-keto steroids activated by garlic extracts. Anales Inst Farmcol Espan 1956; 5: 85–109.

    CAS  Google Scholar 

  466. Tynecka, Z. and Z. Gos. Inhibitory action of garlic (Allium sativum) on growth and respiration of some microorganisms. Acta Microbiol Pol Ser B 1973; 5(1): 51–62.

    CAS  Google Scholar 

  467. Perrin, M., P. Dombray and M. Vlaikovitch. Experimental toxicity of garlic. Compt Rend Soc Biol 1924; 90: 1431–1432.

    CAS  Google Scholar 

  468. Carpenter, C. W. Antibacterial properties of yeasts, Fusarium species, onion and garlic. Hawaiian Planters Record 1945; 49: 41–67.

    CAS  Google Scholar 

  469. Kolodin, A. V. Effect of a preparation containing volatile fractions of garlic on some mechanisms of nonspecific immunity. Sovrem Metody Issled 1968; 1: 101–103.

    Google Scholar 

  470. Virtanen, A. I. and I. Mattila. Gamma-L-glutamyl-s-allyl-L-cysteine in garlic. Suomen Kemistilehti 1961; 34B(3): 44.

    CAS  Google Scholar 

  471. Sugii, M., T. Suzuki, S. Nagasawa and K. Kawashima. Isolation of Gamma-L-glutamyl-s-allylmercapto-L-cysteine and s-allylmercapto L-cysteine from garlic. Chem Pharm Bull 1964; 12(9): 1114–1115.

    Article  PubMed  CAS  Google Scholar 

  472. Suzuki, T., M. Sugii and T. Kakimoto. New gamma-glutamyl peptides in garlic. Chem Pharm Bull 1961; 9: 77–78.

    Article  CAS  Google Scholar 

  473. Suzuki, T., M. Sugii and S. Nagasawa. Isolation of (-)-(s)-propenyl-L-cys-teine from garlic. Chem Pharm Bull 1963; 11:548–549.

    Article  PubMed  Google Scholar 

  474. Okajima, M. Consituents of the pigmented outer skin of onion bulbs. II. The separation of quercetin from the onion skin with aqueous alkaline solutions. Sci Papers Inst Phys Chem Research 1960; 54: 245–246.

    CAS  Google Scholar 

  475. Virtanen, A. I., M. Hatankaka and M. Berlin. Gamma-L-glutamyl-s-propylcysteine in garlic. Suomen Kemistilehti 1962; 35B(3): 52.

    CAS  Google Scholar 

  476. Abdou, I. A., A. A. Abou-Zeid, M. R. El-Sherbeeny and Z. H. Abouel-Gheat. Antimicrobial activities of Allium sativum, Allium cepa, Raphanus sativus, Capsicum frutescens, Eruca sativa, Allium kurrat on bacteria. Qual Plant Mater Veg 1972; 22(1): 29–35.

    Article  CAS  Google Scholar 

  477. Filippov, V. and M. Ii’ina. The state of biotin in plant material. Dokl Akad Naur SSSR 1954; 95: 1267–1270.

    CAS  Google Scholar 

  478. Song, C. S., Y. S. Kim, D. J. Lee and C. C. Nam. A blood anticoagulant substance from garlic: II. Chemical analysis and studies on the biochemical and pharmocological effects. Yonsei Med J 1963;4:21–26.

    PubMed  CAS  Google Scholar 

  479. Suzuki, T., M. Sugii, T. Kakimoto and N. Tsuboi. Isolation of (-) S-allyl-L-cysteine from garlic. Chem Pharm Bull 1961; 9: 251–252.

    Article  CAS  Google Scholar 

  480. Schultz, O. E. and H. L. Mohrmann. Analysis of constituents of garlic (Allium sativum): II. Gas chromatography of garlic oil. Pharmazie 1965; 20(7): 441–447.

    PubMed  CAS  Google Scholar 

  481. Atal, C. K. and J. K. Sethi. Occurrence of amino acids and alliin in the Indian Allium (garlics). Curr Sci 1961; 30: 338–340.

    CAS  Google Scholar 

  482. Granroth, B. Separation of Allium sufur amino acids and peptides by thin-layer electrophoresis and thin-layer chromatography. Acta Chem Scand Ser A 1968; 22(10): 3333–3335.

    Article  CAS  Google Scholar 

  483. AS482 Szabason, A. Hypotensive suppository. Patent-Belg 1963; 631,712: 3pp.

    Google Scholar 

  484. AS483 Liebstein, A. M. Therapeutic effects of various food articles. Amer Med 1927; 33–38.

    Google Scholar 

  485. Seabrook, W. B. Adventures in Arabia Among the Bedouins, Druses, Whirling Dervishes & Yezidee Devil Worshippers. Blue Ribbon Book 1927; 99–105.

    Google Scholar 

  486. Bhatnagar-Thomas, P. L. and A. K. Pal. Insecticidal activity of garlic oil: II. Mode of action of the oil as a pesticide in Musca domestic nebulo and Trogoderma granarium. J Food Sci Technol 1974; 11(4): 153–158.

    CAS  Google Scholar 

  487. Echandi, R. J. An organoleptic and chemical investigation of the linguacheaceric properties of onion (Allium cepa L.) and garlic (Allium sativum L.). Diss Abstr Int B 1966; 26(10): 5632–5633.

    Google Scholar 

  488. Hoerhammer L., H. Wagner, M. Seitz, Z. J. Vejdelek. Evaluation of garlic preparations: I. Chromatographic studies of the actual components of Allium sativum. Pharmazie 1968; 23(8): 462–467.

    CAS  Google Scholar 

  489. AS488 Kominato, K. Separation and purification of metabolism regulators from natural products. Patent-Japan 1970; 18,679: 10pp.

    Google Scholar 

  490. Prasad, D. N., S. K. Bhattacharya, P. K. Das. A study of antiinflammatory activity of some indigenous drugs in albino rats. Indian J Med Res 1966; 54(6): 582–590.

    PubMed  CAS  Google Scholar 

  491. Standen, O. D. Experimental chemotherapy of oxyuriasis. Brit Med J 1953; II: 757–758.

    Article  CAS  Google Scholar 

  492. Kim, M. S. The effect of certain condiments on gastric secretion. Korean Med J 1933; 3: 115–118.

    CAS  Google Scholar 

  493. AS492 Kominato, K. and Y. Kominato. Silkworm attractant, scordinin A, from garlic. Patent-Japan Kokai 1973; 87,009: 3pp.

    Google Scholar 

  494. Joseph, P. K., K. R. Rao and C. S. Sundaresh. Toxic effects of garlic extract and garlic oil in rats. Indian J Exp Biol 1989; 27(11): 977–979.

    PubMed  CAS  Google Scholar 

  495. Amonkar, S. V. and A. Banerji. Isolation and characteristization of larvi-cidal principle of garlic. Science 1971; 174: 1343–1344.

    Article  PubMed  CAS  Google Scholar 

  496. Sivaswamy, S. N., B. Balachandran, S. Balanehru and V. M. Sivaramakrishnan. Mutagenic activity of south Indian food items. Indian J Exp Biol 1991; 29(8): 730–737.

    PubMed  CAS  Google Scholar 

  497. Schimmer, O., A. Kruger, H. Paulini and F. Haefele. An evaluation of 55 commercial plant extracts in the Ames mutagenicity test. Pharmazie 1994; 49(6): 448–451.

    PubMed  CAS  Google Scholar 

  498. Chauhan, J. S., N. K. Singh and S. V. Singh. Screening of higher plants for specific herbicidal principle active against dodder, Cuscuta reflexa Roxb. Indian J Exp Biol 1989; 27(10): 877–884.

    Google Scholar 

  499. Hofbauer, R., M. Frass, B. Gmeiner, A. D. Kaye and E. A. Frost. Effects of garlic extract (Allium sativum) on neutrophil migration at the cellular level. Heart Dis 2001; 3(1): 14–17.

    Article  PubMed  CAS  Google Scholar 

  500. Banerjee, S. K., M. Maulik, S. C. Mancahanda, A. K. Dinda, S. K. Gupta and S. K. Maulik. Dose-dependent induction of endogenous antioxidants in rat heart by chronic administration of garlic. Life Sci 2002; 70(13): 1509–1518.

    Article  PubMed  CAS  Google Scholar 

  501. Ahmed, N., L. Laverick, J. Sammons, H. Zhang, D. J. Maslin and H. T. Hassan. Ajoene, a garlic-derived natural compound, enhances chemotherapy-induced apoptosis in human myeloid leukaemia CD4-positive resistant cells. Anticancer Res 2001; 21(5): 3519–3523.

    PubMed  CAS  Google Scholar 

  502. Kalantari, H. and M. Salehi. The protective effect of garlic oil on hepatoxicity induced by acetaminophen in mice and comparison with N-acetylcysteine. Saudi Med J 2001; 22(12): 1080–1084.

    PubMed  CAS  Google Scholar 

  503. Li, D., B. Jiao and Y. Zhu. Effect and mechanism of garlic juice and hydrogen peroxide on the degradation of lipopolysaccharide. Zhonghua Kou Qiang Yi Xue Za Zhi 2000; 35(5): 333–335.

    PubMed  CAS  Google Scholar 

  504. Izzo, A. A. and E. Ernst. Interactions between herbal medicines and prescribed drugs: A systematic review. Drugs 2001; 61(15): 2163–2175.

    Article  PubMed  CAS  Google Scholar 

  505. Josling, P. Preventing the common cold with a garlic supplement: A double-blind, placebo-controlled survey. Adv Ther 2001; 18(4): 189–193.

    Article  PubMed  CAS  Google Scholar 

  506. Oi, Y., M. Imafuku, C. Shishido, Y. Kominato, S. Nishimura and K. Iwai. Garlic supplementation increases testicular testosterone and decreases plasma corticosterone in rats fed a high protein diet. J Nutr 2001; 131(8): 2150–2156.

    PubMed  CAS  Google Scholar 

  507. Robert, V., B. Mouille, C. Mayuer, M. Michaud and F. Blachier. Effects of the garlic compound diallyl disulfide on the metabolism, adherence and cell cycle of HT-29 colon carcinoma cells: Evidence on sensitive and resistant sub-populations. Carcinogenesis 2001; 22(8): 1155–1161.

    Article  PubMed  CAS  Google Scholar 

  508. Foster, B. C., M. S. Foster, S. Vandenhock, A. Krantis, J. W. Budzinski, J. T. Arnason, K. D. Gallicano and S. Choudri. An in vitro evaluation of human cytochrome P450 3A4 and P-glycoprotein inhibition by garlic. Pharm Pharm Sci 2001; 4(2): 176–184.

    CAS  Google Scholar 

  509. Senapti, S. K., S. Dey, S. K. Dwivedi and D. Swamp. Effect of garlic (Allium sativum L.) extract on tissue lead level in rats. Ethnopharmacol 2001; 76(3): 229–232.

    Article  Google Scholar 

  510. Tsao, S. M. and M. C. Yin. In-vitro antimicrobial activity of four diallyl sulphides occurring naturally in garlic and Chinese leek oils. J Med Microbiol 2001; 50(7): 646–649.

    PubMed  CAS  Google Scholar 

  511. Kannar, D., N. Wattanapenpaiboon, G. S. Savige and M. L. Wahlqvist. Hypocholesterolemic effect of an enteric-coated garlic supplement. J Am Coll Nutr 2001; 20(3): 225–231.

    PubMed  CAS  Google Scholar 

  512. Banerjee, S. K., M. Maulik, S. C. Manchanda, A. K. Dinda, T. K. Das and S. K. Maulik. Garlic-induced alteration in rat liver and kidney morphology and associated changes in endogenous antioxidant status. Food Chem Toxicol 2001; 39(8): 793–797.

    Article  PubMed  CAS  Google Scholar 

  513. Balasenthil, S., C. R. Ramachandran and S. Nagini. Prevention of 4-nitorquinoline 1-oxide-induced rat tongue carcinogenesis by garlic. Fitoterapia 2001; 72(5): 524–531.

    Article  PubMed  CAS  Google Scholar 

  514. Grudzinski, I. P., A. Frankiewicz-Jozko and J. Bany. Diallyl sulfide-a flavour component from garlic (Allium sativum) attenuates lipid peroxidation in mice infected with Trichinella spiralis. Phytomedicine 2001; 8(3): 174–177.

    Article  PubMed  CAS  Google Scholar 

  515. Rahmy, T. R. and K. Z. Hemmaid. Prophylactic action of garlic on the histological and histochemical patterns of hepatic and gastric tissues in rats injected with a snake venom. Nat Toxins 2001; 10(2): 137–165.

    CAS  Google Scholar 

  516. Sheen, L. Y., C. C. Wu, C. K. Lii and S. J. Tsai. Effect of diallyl sulfide and diallyl disulfide, the active principles of garlic, on the anatoxin B(1)-induced DNA damage in primary rat hepatocytes. Toxicol Lett 2001; 122(1): 45–52.

    Article  PubMed  CAS  Google Scholar 

  517. Liu, L. and Y. Y. Yeh. Water-soluble organosulfur compounds of garlic inhibit fatty acid and triglyceride syntheses in cultured rat hepatocytes. Lipids 2001; 36(4): 395–400.

    Article  PubMed  CAS  Google Scholar 

  518. Jarial, M. S. Toxic effect of garlic extracts on the eggs of Aedes aegypti (Diptera: Culicidae): A scanning electron microscope study. J Med Entomol 2001; 38(3): 446–450.

    Article  PubMed  CAS  Google Scholar 

  519. Ohnishi, S. T., T. Onsishi and G. B. Ogunmola. Green tea extract and aged garlic extract inhibit anion transport and sickle cell dehydration in vitro. Blood Cells Mol Dis 2001; 27(1): 48–57.

    Article  Google Scholar 

  520. Moon, D. G., J. Cheon, D H. Yoon, H. S. Park, H. K. Kim, J. J. Kim and S. K. Koh. Allium sativum potentiates suicide gene therapy from murine transitional cell carcinoma. Nutr Cancer 2000; 38(1): 98–105.

    Article  PubMed  CAS  Google Scholar 

  521. Abuharfeil, N. M., M. Salim and S. Von Kleist. Augmentation of natural killer cell activity in vivo against tumour cells by some wild plants from Jordan. Phytother Res 2001; 15(2): 109–113.

    Article  PubMed  CAS  Google Scholar 

  522. Li, G., Z. Shi, H. Jia, J. Ju, X. Wang, Z. Xia, L. Qin, C. Ge, Y. Xu, L. Cheng, P. Chen and G. Yuan. A clinical investigation on garlicin injection for treatment of unstable angina pectoris and its actions on plasma endothelin and blood sugar levels. J Tradit Chin Med 2000; 20(4): 243–246.

    PubMed  CAS  Google Scholar 

  523. Hoshino, T., N. Kashimotoan S. Kasuga. Effects of garlic preparations on the gastrointestinal mucosa. J Nutr 2001; 131(3s): 1109S-1113S.

    PubMed  CAS  Google Scholar 

  524. Sumi, S., T. Tsuneyoshi, H. Matsuo and T. Yoshimatsu. Isolation and characterization of the genes up-regulated in isolated neurons by aged garlic extract (AGE). J Nutr 2001; 131(3s): 1096S–1099S.

    PubMed  CAS  Google Scholar 

  525. Nishiyama, N., T. Moriguchi, N. Morihara and H. Saito. Ameliorative effect of S-allylcysteine, a major thioallyl constituent in aged garlic extract, on learning deficits in senescence-accelerated mice. J Nutr 2001; 131(3s): 1093S–1095S.

    PubMed  CAS  Google Scholar 

  526. Ohnishi, S. T. and T. Ohnishi. In vitro effects of aged garlic extract and other nutritional supplements on sickle erythrocytes. J Nutr 2001; 131(3s): 1085S–1092S.

    PubMed  CAS  Google Scholar 

  527. Kyo, E., N. Uda, S. Kasuga and Y. Itakura. Immunomodulatory effects of aged garlic extract. J Nutr 2001; 131(3s): 1075S–1079S.

    PubMed  CAS  Google Scholar 

  528. Horie, T., S. Awazu, Y. Itakura and T. Fuwa. Alleviation by garlic of antitumor drug-induced damage to the intestine. J Nutr 2001; 131(3s): 1071S–1074S.

    PubMed  CAS  Google Scholar 

  529. Knowles, L. M. and J. A. Milner. Possible mechanism by which allyl sulfides suppress neoplastic cell proliferation. J Nutr 2001; 131(3s): 1061S–1066S.

    PubMed  CAS  Google Scholar 

  530. Pinto, J. T. and R. S. Rivlin. Antiproliferative effects of allium derivatives from garlic. J Nutr 2001; 131(3s): 1058S–1060S.

    PubMed  CAS  Google Scholar 

  531. Song, K. and J. A. Milner. The influence of heating on the anticancer properties of garlic. J Nutr 2001; 131(3s): 1054S–1057S.

    PubMed  CAS  Google Scholar 

  532. Singh, S. V. Impact of garlic organo-sulfides on p21(H-ras) processing. J Nutr 2001; 131(3s): 1046S–1048S.

    PubMed  CAS  Google Scholar 

  533. Moriguchi, T., N. Takasugi and Y. Itakura. The effects of aged garlic extract on lipid peroxidation and the deformability of erythrocytes. J Nutr 2001; 131(3s): 1016S–9S.

    PubMed  CAS  Google Scholar 

  534. Campbell, J. H., J. L. Efendy, N. J. Smith and G. R. Campbell. Molecular basis by which garlic suppresses atherosclerosis. J Nutr 2001; 131(3s): 1006S–1009S.

    PubMed  CAS  Google Scholar 

  535. Ali, M., K. K. Al-Qattan, F. Al-Enezi, R. M. Khanafer and T. Mustafa. Effect of allicin from garlic powder on serum lipids and blood pressure in rats fed with a high cholesterol diet. Prostaglandin Leukot Essent Fatty Acids 2000; 62(4): 253–259.

    Article  CAS  Google Scholar 

  536. Slowing, K., P. Ganado, M. Sanz, E. Ruiz and T. Tejerina. Study of garlic extracts and fractions on cholesterol plasma levels and vascular reactivity in cholesterol-fed rats. J Nutr 2001; 131(3s):994S–999S.

    PubMed  CAS  Google Scholar 

  537. Yeh, Y. Y. and L. Liu. Cholesterol-lowering effect of garlic extracts and organosulfur compounds: Human and animal studies. J Nutr 2001; 131(3s): 989S–993S.

    PubMed  CAS  Google Scholar 

  538. Ryu, K., N. Ide, H. Matsuura and Y. Itakura. N alpha-(1-deoxy-D-fructos-l-yl)-L-arginine, and antioxidant compound identified in aged garlic extract. J Nutr 2001; 131 (3s): 972S–976S.

    PubMed  CAS  Google Scholar 

  539. Ariga, T., K. Tsuj, T. Seki, T. Moritomo and J. I. Yamamoto. Antithrombotic and antineoplastic effects of phyto-organosulfur compounds. Biofactors 2000; 13(1–4): 251–255.

    Article  PubMed  CAS  Google Scholar 

  540. Pedraza-Chaverri, J., M. D. Granados-Silvestri, O. N. Medina-Campos, P. D. Maldonado, I. M. Olivares-Corichi and M. E. Ibarra-Rubio. Post-transcrip-tional control of catalase expression in garlic-treated rats. Mol Cell Biochem 2001; 216(1–2): 9–19.

    Article  PubMed  CAS  Google Scholar 

  541. Shirin, H., J. T. Pinto, Y. Kawabata, J. W. Soh, T. Delohery, S. F. Moss, V. Murty, R. S. Rivlin, P. R. Holt and I. B. Weinstein. Antiproliferative effects of S-allylmercaptocysteine on colon cancer cells when tested alone or in combination with sulindac sulfide. Cancer Res 2001; 61(2): 725–731.

    PubMed  CAS  Google Scholar 

  542. Ghazanfari, T., Z. M. Hassan, M. Ebtekar, A. Ahmadiani, G. Naderi and A. Azar. Garlic induces a shift in cytokine pattern in Leishmania major-infected BALB/c mice. Scand J Immunol 2000; 52(5): 491–495.

    Article  PubMed  CAS  Google Scholar 

  543. Pinto, J. T., C. Qiao, J. Xing, B. P. Suffoletto, K. B. Schubert, R. S. Rivlin, R. F. Huryk, D. J. Bacich and W. D. Heston. Alterations of prostate biomarker expression and testosterone utilization in human LNCaP prostatic carcinoma cells by garlic-derived S-allylmercaptocysteine. Prostate 2000; 45(4): 304–314.

    Article  PubMed  CAS  Google Scholar 

  544. Harris, J. C., S. Plummer, M. P. Turner and D. Lloyd. The microaerophilic flagellate Giardia intestinalis: Allium sativum (garlic) is an effective antigiardial. Microbiology 2000; 146(12): 3119–3127.

    PubMed  CAS  Google Scholar 

  545. Seki, T., K. Tsuji, Y. Hayato, T. Moritomo and T. Ariga. Garlic and onion oils inhibit proliferation and induce differentiation of HL-60 cells. Cancer Lett 2000; 160(1): 29–35.

    Article  PubMed  CAS  Google Scholar 

  546. Pedraza-Chaverri, J., O. N. Medina-Campos, M. A. Granados-Silvestre, P. D. Maldonado, I. M. Olivares-Corichi and R. Hernandez-Pando. Garlic ameliorates hyperlipidemia in chronic aminonucleoside nephrosis. Mol Cell Biochem 2000; 211(1–2): 69–77.

    Article  PubMed  CAS  Google Scholar 

  547. Samaranayake, M. D., S. M. Wickramasinghe, P. Angunawela, S. Jayasekera, S. Iwai and S. Fukushima. Inhibition of chemically induced liver carcinogenesis in Wistar rats by garlic (Alliumsativum). Phytother Res 2000; 14(7): 564–567.

    Article  PubMed  CAS  Google Scholar 

  548. Cho, B. H. and S. Xu. Effects of allyl mercapatan and various allium-derived compounds on cholesterol synthesis and secretion on Hep-G2 cells. Comp Biochem Physiol C Toxicol Pharmacol 2000; 126(2): 195–201.

    PubMed  CAS  Google Scholar 

  549. Hong, Y. S., Y. A. Ham, J. H. Choi and J. Kim. Effects of allyl sulfur compounds and garlic extract on the expression of Bcl-2, Bax, and p53 in non small cell lung cancer cell lines. Exp Mol Med 2000; 32(3): 127–134.

    PubMed  CAS  Google Scholar 

  550. Liu, L. and Y. Y. Yeh. Inhibition of cholesterol biosynthesis by organo-sulfur compounds derived from garlic. Lipids 2000; 35(2): 197–203.

    Article  PubMed  Google Scholar 

  551. Sasaki, J., T. Kita, K. Ishita, H. Uchisawa and H. Matsue. Antibacterial activity of garlic powder against Escherichia coli O-157. J Nutr Sci Vitaminol (Tokyo) 1999; 45(6): 785–790.

    Article  CAS  Google Scholar 

  552. Pantoja, C. V., N. T. Martin, B. C. Norris and C. M. Contreras. Purification and bioassays of a diuretic and natriuretic fraction from garlic (Allium sativum). J Ethnopharmacol 2000; 70(1): 35–40.

    Article  PubMed  CAS  Google Scholar 

  553. Arivazhagan, S., S. Balasenthil and S. Nagini. Modulatory effects of garlic and neem leaf extracts on N-methyl-N’-ni-tro-N-nitrosoguanidine (MNNG) — induced oxidative stress in Wistar rats. Cell Biochem Funct 2000; 18(1): 17–21.

    Article  PubMed  CAS  Google Scholar 

  554. Kasuga, S., M. Ushijima, N. Morihara, Y. Itakura and Y. Nakata. Effect of aged garlic extract (AGE) on hyperglycemia induced by immobilization stress in mice. Nippon Yakurigaku Zasshi 1999; 114(3): 191–197.

    Article  PubMed  CAS  Google Scholar 

  555. Lee, J. H., H. S. Kang and J. Roh. Protective effects of garlic juice against embryotoxicity of methylmercuric chloride administered to pregnant Fischer 344 rats. Yonsei Med J 1999; 40(5): 483–489.

    PubMed  CAS  Google Scholar 

Download references

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2003 Springer Science+Business Media New York

About this chapter

Cite this chapter

Ross, I.A. (2003). Allium sativum L. In: Medicinal Plants of the World. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-365-1_3

Download citation

  • DOI: https://doi.org/10.1007/978-1-59259-365-1_3

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-469-2

  • Online ISBN: 978-1-59259-365-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics