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The Epidemiology of Influenza

  • Chapter
Influenza

Abstract

If the diagnosis of influenza in the individual patient is at times ambiguous, the identification of influenza epidemics is not. In the north temperate zone, the abrupt appearance of febrile respiratory disease affecting adults as well as children in the early winter can be assumed to be influenza pending virologic con-firmation. Characteristically, sporadic cases are seen in late November and December; then, following the Christmas holidays, the disease becomes epidemic. School and industrial absenteeism and clinic visits increase, and somewhat later excess mortality related to pneumonia occurs.

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References

  • Aho, K., Pyhälä, R., and Visakorpi, R., 1980, ABO associated genetic determinant in H1N1 influenza, Tissue Antigens 16:310–313.

    Article  PubMed  CAS  Google Scholar 

  • Andrewes, C. H., 1951, Epidemiology of influenza in the light of the 1951 outbreak, Proc. R. Soc. Med. 44:803–804.

    PubMed  CAS  Google Scholar 

  • Assaad, F., Brès, P., and Delon, P., 1977, Surveillance internationale de la grippe, Rev. Epidemiol. Sante Publ. 25:441–445.

    Google Scholar 

  • Baine, W. B., Luby, J. P., and Martin, S. M., 1980, Severe illness with influenza B, Am. J. Med. 68:181.

    Article  PubMed  CAS  Google Scholar 

  • Barb, K., and Takatsy, G. Y., 1973, Unusual features of the 1971 influenza epidemic in Hungary and the antigen analysis of the isolates by a serum adsorption test, Bull. WHO 49:21–24.

    PubMed  CAS  Google Scholar 

  • Barker, W. H., and Mullooly, J. P., 1980, Impact of epidemic type A influenza in a defined adult population, Am. J. Epidemiol. 112:798–813.

    PubMed  CAS  Google Scholar 

  • Barker, W. H., and Mullooly, J. P., 1981, Underestimation of the role of pneumonia and influenza in causing excess mortality, Am. J. Public Health 71:643–645.

    Article  PubMed  CAS  Google Scholar 

  • Barker, W. H., and Mullooly, J. P., 1982, Re: “A study of excess mortality during influenza epidemics in the United States, 1968–1976,” Am. J. Epidemiol. 115:479–480.

    PubMed  CAS  Google Scholar 

  • Baroyan, O. V., Rvachev, L. A., Basilevsky, U. V., et al., 1971, Adv. Appl. Probabil. 3:224–226.

    Article  Google Scholar 

  • Bean, W. J., Jr., Cox, N. J., and Kendal, A. P., 1980, Recombination of human influenza A viruses in nature, Nature 284:638–640.

    Article  PubMed  CAS  Google Scholar 

  • Bean, B., Rhame, F. S., Hughes R. S., et al., 1983, Influenza B: Hospital activity during a community epidemic, Diag. Microbiol. Infect. Dis. 1:177–183.

    Article  CAS  Google Scholar 

  • Beare, A. S., Bynoe, M. L., and Tyrrell, D. A. J., 1968, Investigation into the attenuation of influenza viruses by serial passage, Br. Med. J. 4:482–484.

    Article  PubMed  CAS  Google Scholar 

  • Belbin, D. J., and Smithson, W. H., 1979, “Red ’flu”: A study of an epidemic in a girls’ boarding school in February 1978, J. R. Coll. Gen. Practit. 29:151–154.

    CAS  Google Scholar 

  • Beveridge, W. I. B., 1977, Influenza: The Last Great Plague. An Unfinished Story of Discovery. Heineman, London.

    Google Scholar 

  • Beyer, W. E. P., and Masurel, N., 1985, Antigenic heterogeneity among influenza A(H3N2) field isolates during an outbreak in 1982/83, estimated by methods of numerical taxonomy, J. Hyg. (Camb.) 94:97–109.

    Article  CAS  Google Scholar 

  • British Medical Journal ,1974, Epidemiology. Seasonal variations in influenza, Br. Med. J. 2:511.

    Article  Google Scholar 

  • Buchan, K. A., and Reid, D., 1972, Epidemiological aspects of influenza in Lewis, Health Bull. 30:183–186.

    CAS  Google Scholar 

  • Buonagurio, D. A., Nakada, S., Desselberger, U., et al. 1985, Noncumulative sequence changes in the hemagglutinin genes of influenza C virus isolates, Virology 146:221–232.

    Article  PubMed  CAS  Google Scholar 

  • Carey, D. L., Dunn, F. L., Robinson, R. Q., 1958, Communitywide epidemic of Asian Strain influenza. Clinical and subclinical illness among school children, J.A.M.A. 167:1459–1463.

    Article  CAS  Google Scholar 

  • Centers for Disease Control, 1985, Influenza-United States, 1984–1985 season, Morbid. Mortal. Weekly Rep. 34:440–443.

    Google Scholar 

  • Choi, K., and Thacker, S. G., 1981, An evaluation of influenza mortality surveillance, 1962–1979. II. Percentage of pneumonia and influenza deaths as an indicator of influenza activity, Am. J. Epidemiol. 113:227–235.

    PubMed  CAS  Google Scholar 

  • Choi, K., and Thacker, S. G., 1982, Mortality during influenza epidemics in the United States, 1967–1978, Am. J. Public Health. 72:1280–1283.

    Article  PubMed  CAS  Google Scholar 

  • Clarke, S. K. R., Heath, R. B., Sutton, R. N. P., et al., 1958, Serological studies with Asian strain influenza A, Lancet 1:814–818.

    Article  PubMed  CAS  Google Scholar 

  • Clifford, R. E., Smith, J. W. G., Tillett, H. E., 1977, Excess mortality associated with influenza in England and Wales, Int. J. Epidemiol. 6:115–128.

    Article  PubMed  CAS  Google Scholar 

  • Coates, D. M., Husseini, R. H., Rushton, D. I., et al., 1984, The role of lung development in the age-related susceptibility of ferrets to influenza virus, Br. J. Exp. Pathol. 65:543–547.

    PubMed  CAS  Google Scholar 

  • Collins, S. D., Frost, W. H., Gover, M., et al., 1930, Mortality from influenza and pneumonia in 50 large cities of the United States, 1910–1929, Public Health Rep. 45:2277–2329.

    Article  Google Scholar 

  • Cox, N. J., Bai, Z. S., and Kendal, A. P., 1983, Laboratory-based surveillance of influenza A(H1N1) and A(H3N2) viruses in 1980–81: Antigenic and genomic analyses, Bull. WHO 61:143–152.

    PubMed  CAS  Google Scholar 

  • Crosby, A. W., 1976, Epidemic and Peace, 1918 ,Greenwood Press, Westport, CT.

    Google Scholar 

  • Dalton, K., 1977, The Premenstrual Syndrome and Progesterone Therapy ,Heinemann Medical Books, London.

    Google Scholar 

  • Daniels, R. S., Douglas, A. R., Skehel, J. J., et al., 1985, Antigenic and amino acid sequence analyses of influenza viruses of the H1N1 subtype isolated between 1982 and 1984, Bull. WHO 63:273–277.

    PubMed  CAS  Google Scholar 

  • Davey, M. L., and Reid, D., 1972, Relationship of air temperature to outbreaks of influenza, Br. J. Prev. Soc. Med. 26:28–32.

    PubMed  CAS  Google Scholar 

  • Davies, J. R., Grilli, E. A., and Smith, A. J., 1984, Influenza A: Infection and reinfection, J. Hyg. (Camb.) 92:125–127.

    Article  CAS  Google Scholar 

  • Dingle, J. H., Badger, G. F., and Jordan, W. S., 1964, Illness in the Home ,The Press of Western Reserve University, Cleveland.

    Google Scholar 

  • Dowdle, W. R., Coleman, M. T., and Gregg, M. B., 1974, Natural history of influenza type A in the United States, 1957–1972, Prog. Med. Virol. 17:91–135.

    PubMed  CAS  Google Scholar 

  • Dunn, F. L., 1958, Pandemic influenza in 1957. Review of international spread of new Asian strain, J.A.M.A. 166:1140–1148.

    Article  CAS  Google Scholar 

  • Dykes, A. C., Cherry, J. D., and Nolan, C. E., 1980, A clinical, epidemiologic, serologic, and virologic study of influenza C virus infection, Arch. Intern. Med. 140:1295–1298.

    Article  PubMed  CAS  Google Scholar 

  • Effros, R. B., and Walford, R. L., 1983, The immune response of aged mice to influenza: Diminished T-cell proliferation, interleukin 2 production and cytotoxicity, Cell. Immunol. 81:298–305.

    Article  PubMed  CAS  Google Scholar 

  • Eickhoff, T. C., Sherman, I. L., and Serfling, R. E., 1961, Excess mortality associated with epidemic influenza, J.A.M.A. 176:776.

    Article  PubMed  CAS  Google Scholar 

  • Elliott, R. M., Guo, Y., and Desselberger, U., 1984, Polypeptide synthesis in MDCK cells infected with human and pig influenza C viruses,J. Gen. Virol. 65:1873–1880, 1984.

    Article  PubMed  CAS  Google Scholar 

  • Elveback, L. R., Fox, J. P., Ackerman, E., et al., 1976, An influenza simulation model for immunization studies, Am. J. Epidemiol. 103:152–165.

    PubMed  CAS  Google Scholar 

  • Evans, A. S., Shepard, K., and Richards, V., 1970, Blood-groups and influenza, Lancet 2:1364.

    Article  PubMed  CAS  Google Scholar 

  • Farr, W., 1885, Vital Statistics ,Office of the Sanitary Institute, London, p. 330.

    Google Scholar 

  • Finklea, J. F., Sandifer, S. H., and Smith, D. D., 1969, Cigarette smoking and epidemic influenza, Am. J. Epidemiol. 90:390–399.

    PubMed  CAS  Google Scholar 

  • Fox, J. P., and Hall, C. E., 1980, Viruses in Families ,PSG Publishing, Littleton, MA.

    Google Scholar 

  • Fox, J. P., and Kilbourne, E. D., 1973, Epidemiology of influenza-Summary of influenza workshop IV, J. Infect. Dis. 128:361–386.

    Article  Google Scholar 

  • Fox, J. P., Hall, C. E., Cooney, M. K., et al., 1982, Influenzavirus infections in Seattle families, 1975–1979. I. Study design, methods and the occurrence of infections by time and age, Am. J. Epidemiol. 116:212–227.

    PubMed  CAS  Google Scholar 

  • Foy, H. M., Hall, C., Cooney, M.K., et al., 1979, Influenza surveillance by age and target group, Am. J. Epidemiol. 109:582–587.

    PubMed  CAS  Google Scholar 

  • Francis, T., Jr., 1958, Influenza. Epidemiology. Influenza as a military problem, in: Preventive Medicine in World War II. Vol. IV. Communicable Diseases (J. B. Coates, Jr., E. D. Hoff, and P. M. Hoff, eds.), The Surgeon General, Department of the Army, Washington, pp. 85–128.

    Google Scholar 

  • Frank, A. L., Taber, L. H., and Wells, J. M., 1983, Individuals infected with two subtypes of influenza A virus in the same season, J. Infect. Dis. 147: 120–124.

    Article  PubMed  CAS  Google Scholar 

  • Frank, A. L., Taber, L. H., Glezen, W. P., et al., 1979, Reinfection with influenza A (H3N2) virus in young children and their families, J. Infect. Dis. 140:829–835.

    Article  PubMed  CAS  Google Scholar 

  • Ghendon, Y., Klimov. A., Gorodkova, N., et al., 1981, Genome analysis of influenza A virus strains isolated during an epidemic of 1979–1980, J. Gen. Virol. 56:303–313.

    Article  PubMed  CAS  Google Scholar 

  • Glezen, W. P., 1982, Serious morbidity and mortality associated with influenza epidemics, Epidemiol. Rev. 4:25–44.

    PubMed  CAS  Google Scholar 

  • Glezen, W. P., and Couch, R. B., 1978, Interpandemic influenza in the Houston area, 1974–76, N. Engl. J. Med. 298:587–592.

    Article  PubMed  CAS  Google Scholar 

  • Glezen, W. P., Couch, R. B., Six, H. R. 1982a, The influenza herald wave, Am. J. Epidemiol. 116:589–598.

    PubMed  CAS  Google Scholar 

  • Glezen, W. P., Payne, A. A., Snyder, D. N., et al., 1982b, Mortality and influenza, J. Infect. Dis. 146:313–321.

    Article  PubMed  CAS  Google Scholar 

  • Glezen, W. P., Six, H. R., Perrotta, D. M., et al., 1984, Epidemics and their causative viruses-Community experience, in: The Molecular Virology and Epidemiology of Influenza (C. Stuart-Harris and C. W. Potter, eds.), Academic Press, pp. 17–38.

    Google Scholar 

  • Goldstein, I. F., and Block, G., 1976, A method for surveillance of influenza epidemics, Am. J. Public Health 66:992–993.

    Article  PubMed  CAS  Google Scholar 

  • Guo, Y., and Desselberger, U., 1984, Genome analysis of influenza C viruses isolated in 1981/82 from pigs in China, J. Gen. Virol. 65:1857–1872.

    Article  Google Scholar 

  • Haaheim, L. R., 1980, Surveillance of the antibody status to current influenza strains in the Norwegian population. 2: Antibodies to the A/USSR/90/77(HlNl) virus in the various age groups after the second epidemic wave, Natl. Inst. Public Health Ann. 3:49–56.

    CAS  Google Scholar 

  • Haesebrouck, F., Biront, P., Pensaert, M. B., et al., 1985, Epizootics of respiratory tract disease in swine in Belgium due to H3N2 influenza virus and experimental reproduction of disease, Am J. Vet. Res. 46: 1926–1928.

    PubMed  CAS  Google Scholar 

  • Hall, C. E., Cooney, M. K., and Fox, J. P., 1973, The Seattle virus watch. IV. Comparative epidemiologic observations of infections with influenza A and B viruses, 1965–1969, in families with young children, Am. J. Epidemiol. 98:365–380.

    PubMed  CAS  Google Scholar 

  • Hall, W. N., Goodman, R. A., Noble, G. R., et al., 1981, An outbreak of influenza B in an elderly population,J. Infect. Dis. 144:297–302.

    Article  PubMed  CAS  Google Scholar 

  • Hayslett, J., McCarroll, J., Brady, E., et al., 1962, Endemic influenza. I. Serologic evidence of continuing and subclinical infection in disparate populations in the post-pandemic period, Am. Rev. Respir. Dis. 85: 1–8.

    PubMed  CAS  Google Scholar 

  • Hemmes, J. H., Winkler, K. C., and Kool, S. M., 1960, Virus survival as a seasonal factor in influenza and poliomyelitis, Nature 188:430–431.

    Article  PubMed  CAS  Google Scholar 

  • Homma, M., 1985, Epidemiological characteristics of type C influenza, J. Cell. Biochem. (Suppl.) 9C:278.

    Google Scholar 

  • Hope-Simpson, R. E., 1981, The role of season in the epidemiology of influenza, J. Hyg. (Camb.) 86:35–47.

    Article  CAS  Google Scholar 

  • Hoskins, T. W., Davies, J. R., Smith, A. J., et al., 1979, Assessment of inactivated influenza A vaccine after three outbreaks of influenza A at Christ’s Hospital, Lancet 1:33–35.

    Article  PubMed  CAS  Google Scholar 

  • Housworth, J., and Langmuir, A. D., 1974, Excess mortality from epidemic influenza, 1957–1966, Am. J. Epidemiol. 100:40–48.

    PubMed  CAS  Google Scholar 

  • Isaacs, A., Hart, R. J. C., and Law, V. G., 1962, Influenza viruses, 1957–1960, Bull. WHO 26:253–259.

    PubMed  CAS  Google Scholar 

  • Jennings, L. C., and Miles, J. A. R., 1978, A study of acute respiratory disease in the community of Port Chalmers. II. Influenza A/Port Chalmers/1/73: intrafamilial spread and the effect of antibodies to the surface antigens,J. Hyg. (Camb.) 81:67–75.

    Article  CAS  Google Scholar 

  • Jensen, K. E., 1957, Immunologic significance of antigenic differences among strains of influenza A isolated during the same epidemic, J. Immunol. 78:373–379.

    PubMed  CAS  Google Scholar 

  • Kark, J. D., Lebiush, M., and Rannon, L., 1982, Cigarette smoking as a risk factor for epidemic A(HiNi) influenza in young men, N. Engl. J. Med. 307:1042–1046.

    Article  PubMed  CAS  Google Scholar 

  • Kavet, J., 1977, A perspective on the significance of pandemic influenza, Am. J. Public Health. 67:1063–1070.

    Article  PubMed  CAS  Google Scholar 

  • Kawamura, H., Tashiro, M., Kitame, F., et al., 1986, Genetic variation among human strains of influenza C virus isolated in Japan, Virus Res. 4:275–288.

    Article  PubMed  CAS  Google Scholar 

  • Kawaoka, Y., and Webster, R. G., 1985, Evolution of the A/chicken/PennsylvaniaF83 (H5N2) influenza virus, Virology 146:130–137.

    Article  PubMed  CAS  Google Scholar 

  • Kendal, A. P., Schieble, J., Cooney, M. K., et al., 1978, Co-circulation of two influenza A (H3N2) antigenic variants detected by virus surveillance in individual communities, Am. J. Epidemiol. 108:308–311.

    PubMed  CAS  Google Scholar 

  • Kendal, A. P., Joseph, J. M., Kobayashi, G., et al., 1979, Laboratory-based surveillance of influenza virus in the United States during the winter of 1977–1978, Am. J. Epidemiol. 110:449–461.

    PubMed  CAS  Google Scholar 

  • Kermack, W. O., and McKendrick, A. G., et al., 1927, A contribution to the mathematical theory of epidemics, Proc. R. Soc. Al 15:700–721.

    Article  Google Scholar 

  • Kilbourne, E. D., 1961, Influenza-the cryptic killer, Am. Rev. Resp. Dis. 83:265–266.

    PubMed  CAS  Google Scholar 

  • Kilbourne, E. D., 1963, Infections primarily of the respiratory tract, in: Preventive Medicine and Public Health (W. G. Smillie and E. D. Kilbourne, eds.), Macmillan, New York, p. 192.

    Google Scholar 

  • Kilbourne, E. D., 1973, The molecular epidemiology of influenza. J. Infect. Dis. 127:478–487.

    Article  PubMed  CAS  Google Scholar 

  • Kilbourne, E. D., 1975, Epidemiology of influenza, in: The Influenza Viruses and Influenza (E. D. Kilbourne, ed.), Academic Press, New York, pp. 483–538.

    Google Scholar 

  • Kilbourne, E. D., 1979, Molecular epidemiology-influenza as archetype, Harvey Lect. 73:225–258.

    PubMed  CAS  Google Scholar 

  • Kilbourne, E. D., 1980, Influenza: Viral determinants of the pathogenicity and epidemicity of an invariant disease of variable occurrence, Phil Trans. R. Soc. Lond. [Biol] 288:291–297.

    Article  CAS  Google Scholar 

  • Kilbourne, E. D., Anderson, H. C., and Horsfall, F. L., Jr., 1951, Concurrent infection with influenza A and B viruses in a single epidemic, J. Immunol 67:547–558.

    PubMed  CAS  Google Scholar 

  • Klimov, A. I., and Ghendon, Y. Z., 1981, Genome analysis of H1N1 influenza virus strains isolated in the U.S.S.R. during an epidemic in 1961–1962, Arch. Virol. 70:225–232.

    Article  PubMed  CAS  Google Scholar 

  • Knox, J. D. E., and Anderson, R. A., 1982, Influenza-like illness: A monitoring system, Ecology Dis. 1:87–91.

    CAS  Google Scholar 

  • LaMontagne, J. R., 1980, Summary of a workshop on influenza B viruses and Reye’s syndrome, J. Infect. Dis. 142:452–465.

    Article  PubMed  CAS  Google Scholar 

  • Langmuir, A. D., 1961, Epidemiology of Asian influenza. With special emphasis on the United States, Am. Rev. Respir. Dis. 83:2–14.

    PubMed  Google Scholar 

  • Layde, P. M., Engelberg, A. L., Dobbs, H. I., et al., 1980, Outbreak of influenza A/USSR/77 at Marquette University, J. Infect. Dis. 142:347–352.

    Article  PubMed  CAS  Google Scholar 

  • Lebiush, M., Rannon, L., and Kark, J. D., 1981, The relationship between epidemic influenza A(HiNi) and ABO blood groups, J. Hyg. (Camb.) 87:139–146.

    Article  CAS  Google Scholar 

  • Levine, M. M., Togo, Y., and Wald, E. R., 1974, Practicability of influenza surveillance by virus culture of children, Am. J. Epidemiol. 100:272–276.

    PubMed  CAS  Google Scholar 

  • Lim, K. A., Smith, A., Hale, J. H., et al., 1957, Influenza outbreak in Singapore, Lancet 2:791–796.

    Article  Google Scholar 

  • Longini, I. M., Jr., Monto, A. S., and Koopman, J., 1984a, Statistical procedures for estimating the community probability of illness in family studies: Rhinovirus and influenza, Int. J. Epidemiol. 13:99–106.

    Article  PubMed  Google Scholar 

  • Longini, I. M., Jr., Seaholm, S. K., Ackerman, E., et al., 1984b, Simulation studies of influenza epidemics: Assessement of parameter estimation and sensitivity, Int. J. Epidemiol. 13:496–501.

    Article  PubMed  Google Scholar 

  • Lvov, D. K., Zhdanov, V. M., Sadykhova, F., et al., 1983, Isolation of a natural recombinant of influenza A virus (H1N3) from a sick child, Lancet 2:1246–1247.

    Article  PubMed  CAS  Google Scholar 

  • Macfarlare, A., 1977, Daily mortality and environment in English conurbations. I. Air pollution, low temperature, and influenza in Greater London, Br. J. Prev. Soc. Med. 31:54–61.

    Google Scholar 

  • MacKenzie, J. S., and Fimmel, P. J., 1978, The effect of ABO blood groups on the incidence of epidemic influenza and on the response to live attenuated and detergent split influenza virus vaccines, J. Hyg. (Camb.) 80:21–30.

    Article  CAS  Google Scholar 

  • MacKenzie, J. S., MacKenzie, I. H., and Holt, P. G., 1976, The effect of cigarette smoking on susceptibility to epidemic influenza and on serological responses to live attenuated and killed subunit influenza vaccines, J. Hyg. (Camb.) 77:409–417.

    Article  CAS  Google Scholar 

  • Mann, P. G., Pereira, M. S., Smith, J. W. G., et al., 1981, A five-year study of influenza in families, J. Hyg. (Camb.) 87:191–200.

    Article  CAS  Google Scholar 

  • Marine, W. M., McGowan, J. E., Jr., and Thomas, J. E., 1976, Influenza detection: A prospective comparison of surveillance methods and analysis of isolates, Am. J. Epidemiol. 104:248–255.

    PubMed  CAS  Google Scholar 

  • Mathur, U., Bentley, D. W., Hall, C. B., et al., 1981, Influenza A/Brazil/78(H1N1) infection in the elderly, Am. Rev. Respir. Dis. 123:633–635.

    PubMed  CAS  Google Scholar 

  • Maxwell, E. S., Ward, T. G., and Van Metre, T. E., Jr., 1949, The relation of influenza virus and bacteria in the etiology of pneumonia, J. Clin. Invest. ,28:307–318.

    Article  Google Scholar 

  • Miller, D. L., Reid, D., Diamond, J. R., et al., 1973, Hong Kong influenza in the Royal Air Force 1968–70, J. Hyg. (Camb.J 71:535–547.

    Article  CAS  Google Scholar 

  • Montefiore, D., Drozdov, S. G., Kafuko, G. W., et al., 1970, Influenza in East Africa, 1969–70, Bull. WHO 43:269–273.

    PubMed  CAS  Google Scholar 

  • Monto, A. S., and Kioumehr, F., 1975, The Tecumseh study of respiratory illness. IX. Occurrence of influenza in the community, 1966–1971, Am. J. Epidemiol. 102:553–563.

    PubMed  CAS  Google Scholar 

  • Monto, A. S., and Maassab, H. F., 1981, Serologic responses to nonprevalent influenza A viruses during intercyclic periods, Am. J. Epidemiol. 113:236–244.

    PubMed  CAS  Google Scholar 

  • Moore, B. W., Webster, R. G., Bean, W. J., et al., 1981, Reappearance in 1979 of a 1968 Hong Konglike influenza virus, Virology 109:219–222.

    Article  PubMed  CAS  Google Scholar 

  • Moser, M. R., Bender, T. R., Margolis, H. S., et al., 1979, An outbreak of influenza aboard a commercial airliner, Am. J. Epidemiol. 110:1–6.

    PubMed  CAS  Google Scholar 

  • Mulder, J., and Masurel, N., 1958, Pre-epidemic antibody against 1957 strain of Asiatic influenza, Lancet 2:810–814.

    Article  Google Scholar 

  • Nakada, S., Creager, R. S., Krystal, M., et al., 1984a, Influenza C virus hemagglutinin: Comparison with influenza A and B virus hemagglutinins, J. Virol. 50:118–124.

    PubMed  CAS  Google Scholar 

  • Nakada, S., Creager, R. S., Krystal, M., et al., 1984b, Complete nucleotide sequence of the influenza C/California/78 virus nucleoprotein gene, Virus Res. 1:433–441.

    Article  PubMed  CAS  Google Scholar 

  • Nakajima, K., Desselberger, U., and Palese, P., 1978, Recent human influenza A (H1N1) viruses are closely related genetically to strains isolated in 1950, Nature 274:334–339.

    Article  PubMed  CAS  Google Scholar 

  • Nakajima, K., Nakajima, S., Nerome, K., et al., 1979, Genetic relatedness of some 1978–1979 influenza H1N1 strains to 1953 H1N1 strain, Virology 99:423–426.

    Article  PubMed  CAS  Google Scholar 

  • Napiorkowski, P. A., and Black, F. L., 1974, Influenza A in an isolated population in the Amazon, Lancet 2:1390–1391.

    Article  PubMed  CAS  Google Scholar 

  • Nishikawa, F., and Sugiyama, T., 1983, Direct isolation of H1N2 recombinant virus from a throat swab of a patient simultaneously infected with H1N1 and H3N2 influenza A viruses, J. Clin. Microbiol 18:425–427.

    PubMed  CAS  Google Scholar 

  • Nolan, T. F., Goodman, R. A., Hinman, A. R., et al., 1980, Morbidity and mortality associated with influenza B in the United States, 1979–1980: A report from the Center for Disease Control, J. Infect. Dis. 142:360–362.

    Article  PubMed  Google Scholar 

  • Olson, J. G., and Irving, G. S., 1979, An explosive outbreak of influenza caused by A/USSR/77-like virus on a United States naval ship, Mil. Med. 144:743–745.

    PubMed  CAS  Google Scholar 

  • Palese, P., and Young, J. F., 1983, Molecular epidemiology of influenza, in: Influenza Virus Genetics (P. Palese and D. W. Kingsbury, eds.), Springer-Verlag, New York, pp. 321–336.

    Chapter  Google Scholar 

  • Palese, P., Elliott, R. M., Baez, M., et al., 1981, Genome diversity among influenza A, B and C viruses and genetic structure of RNA 7 and RNA 8 of influenza A viruses, in: Genetic Variation among Influenza Viruses (D. P. Nayak, ed.), Academic Press, New York, pp. 127–140.

    Google Scholar 

  • Pereira, M. S., and Chakraverty, P., 1977, The laboratory surveillance of influenza epidemics in the United Kingdom 1968–1976, J. Hyg. (Camb.) 79:77.

    Article  CAS  Google Scholar 

  • Pereira, M. S., and Chakraverty, P., 1982, Influenza in the United Kingdom 1977–1981, J. Hyg, (Camb.) 88:501–512.

    Article  CAS  Google Scholar 

  • Pereira, M., Assaad, F. A., and Delon, P. J., 1978, Influenza surveillance, Bull. WHO 56:193–203.

    Google Scholar 

  • Peretjagina, N. S., Antonova, I. V., and Urbah, V. J., 1977, The upper tolerance limits of nonepidemic daily morbidity for influenza and other acute respiratory diseases in the epidemic season, Bull. WHO 55:761–763.

    PubMed  CAS  Google Scholar 

  • Peterson, D., Andrews, J. S., Jr., Levy, B. S., et al., 1979, An effective school-based influenza surveillance system, Public Health Rep. 94:88–92.

    PubMed  CAS  Google Scholar 

  • Pfeifer, J. B., and Compans, R. W., 1984, Structure of the influenza C glycoprotein gene as determined from cloned DNA, Virus Res. 1:281–296.

    Article  PubMed  CAS  Google Scholar 

  • Plesnik, V., Heinz, F., Matuska, J., et al., 1978, Economic losses in influenza epidemics, Cas. Lek. Cesk. 117:53–57.

    PubMed  CAS  Google Scholar 

  • Poe, G. S., and Massey, J. T., 1977, Estimating influenza cases and vaccinations by means of weekly rapid reporting system. Methodological considerations and results obtained in the U.S. Health Interview Survey, Public Health. Rep. 92:299–306.

    PubMed  CAS  Google Scholar 

  • Pons, V. G., Canter, J., and Dolin, R., 1980, Influenza A/USSR/77 (H1N1) on a university campus, Am. J. Epidemiol. 111:23–30.

    PubMed  CAS  Google Scholar 

  • Potter, C. W., and Schild, G. C., 1967, The incidence of HI antibody to influenza virus A2/Singa-pore/1/57 in individuals of blood groups A and O, J Immunol. 98:1320–1325.

    PubMed  CAS  Google Scholar 

  • Pyhälä, R., and Aho, K., 1982, Seroepidemiology of H1N1 influenza: The range of the affected population is widening, Med. Biol. 60:328–332.

    PubMed  Google Scholar 

  • Pyhälä, R., Aho, K., and Visakorpi, R., 1979, Seroepidemiology of H1N1 influenza: Striking differences in the attack rate among young people, Acta Pathol Microbiol. Scand. B87:161–164.

    Google Scholar 

  • Retailliau, H. F., Storch, G. A., Curtis, A. C., et al., 1979, The epidemiology of influenza B in a rural setting in 1977, Am. J. Epidemiol. 109:639–649.

    PubMed  CAS  Google Scholar 

  • Rosenstock, I. M., Hochbaum, G. M., Leventhal, H., et al., 1960, The Impact of Asian Influenza on Community Life. A Study in Five Cities ,U.S. Dept. of Health, Education, and Welfare, Bethesda.

    Google Scholar 

  • Rubin, R. J., and Gregg, M. B., 1975, Influenza surveillance in the United States, 1972–1974, Am. J. Epidemiol. 102:225–232.

    PubMed  CAS  Google Scholar 

  • Sartwell, P. E., and Long, A. P., 1948, The Army experience with influenza, 1946–1947. I. Epidemiological aspects, Am. J. Hyg. 47:135–141.

    PubMed  CAS  Google Scholar 

  • Schild, G. C., Henry-Aymard, M., Pereira, M. S., et al., 1973, Antigenic variation in current human type A influenza viruses: Antigenic characteristics of the variants and their geographic distribution, Bull. WHO 48:269–278.

    PubMed  CAS  Google Scholar 

  • Schild, G. C., Newman, R. W., McGregor, I. A., et al., 1977, The use of transportable single-radial-diffusion immunoplates in seroepidemiological studies of influenza in the Gambia. The occurrence and persistence of antibody to influenza A/Hong Kong/68 (H3N2) virus in selected inhabitants of two rural villages, Bull. WHO 55:3–13.

    PubMed  CAS  Google Scholar 

  • Schoenbaum, S. C., McNeil, B. J., and Kavet, J., 1976, The Swine-influenza decision, N. Engl. J. Med. 295:759–765.

    Article  PubMed  CAS  Google Scholar 

  • Scholtissek, C., Rohde, W., von Hoyningen, V., et al., 1978a, On the origin of the human influenza subtypes H2N2 and H3N2, Virology 87:13–20.

    Article  PubMed  CAS  Google Scholar 

  • Scholtissek, C., von Hoyningen, V., and Rott, R., 1978b, Genetic relatedness between the new 1977 epidemic strains (H1N1) of influenza and human influenza strains isolated between 1947 and 1957 (H1N1), Virology 89:613–617.

    Article  PubMed  CAS  Google Scholar 

  • Schulman, J. L., and Kilbourne, E. D., 1963a, Experimental transmission of influenza virus infection in mice. I. The period of transmissibility, J. Exp. Med. 118:257–266.

    Article  PubMed  CAS  Google Scholar 

  • Schulman, J. L., and Kilbourne, E. D., 1963b, Experimental transmission of influenza virus infection in mice. II. Some factors affecting the incidence of transmitted infection, J. Exp. Med. 118:267–275.

    Article  PubMed  CAS  Google Scholar 

  • Schulman, J. L., and Kilbourne, E. D., 1966, Seasonal variations in the transmission of influenza virus infection in mice, in Biometeorology II. Proceedings Third International Biometeorology Congress, Pau, S. France, 1–7 Sept., 1963 ,Pergamon Press, New York, pp. 83–87.

    Google Scholar 

  • Selby, P., 1982, Influenza Models. Prospects for Development and Use, MTP Press, Lancaster.

    Google Scholar 

  • Serfling, R. E., 1963, Methods for current statistical analysis of excess pneumonia-influenza deaths, Public Health. Rep. 78:494–506.

    Article  PubMed  Google Scholar 

  • Shadrin, A. S., Marinich, I. G., and Taros, L. Y., 1977, Experimental and epidemiological estimation of seasonal and climatogeographical features of non-specific resistance of the organism to influenza, J. Hyg. Epidemiol. Microbiol. Immunol. 21:155–161.

    PubMed  CAS  Google Scholar 

  • Shen, F.-Z., Zhao, G.-F., and Xu, X.-L., 1983, Influenza surveillance, Chin. Med. J. 96:349–354.

    PubMed  CAS  Google Scholar 

  • Six, H. R., Webster, R. G., Kendal, A. P., et al., 1983, Antigenic analysis of H1N1 viruses isolated in the Houston metropolitan area during four successive seasons, Infect. Immun. 42:453–458.

    PubMed  CAS  Google Scholar 

  • Sonoguchi, T., Naito, H., Hara, M., et al., 1985, Cross-subtype protection in humans during sequential, overlapping, and/or concurrent epidemics caused by H3N2 and H1N1 influenza viruses, J. Infect. Dis. 151:81–88.

    Article  PubMed  CAS  Google Scholar 

  • Spelman, D. W., and McHardy, C. J., 1985, Concurrent outbreaks of influenza A and influenza B, J. Hyg. (Camb.) 94:331–339.

    Article  CAS  Google Scholar 

  • Spencer, M. J., Cherry, J. D., and Teresaki, P. I., 1976, HL-A antigens and antibody response after influenza A vaccination. Decreased response associated with HL-A type W16, N. Engl. J. Med. 294:13–16.

    Article  PubMed  CAS  Google Scholar 

  • Spicer, C. C., and Lawrence, C. J., 1984, Epidemic influenza in Greater London, J. Hyg. (Camb.) 93:105–112.

    Article  CAS  Google Scholar 

  • Stuart-Harris, C. H., Laird, J., Tyrrell, D. A., et al., 1949, The relationship between influenza and pneumonia, J Hyg. 47:434–448.

    Article  CAS  Google Scholar 

  • Taber, L. H., Paredes, A., Glezen, W. P., et al., 1981, Infection with influenza A/Victoria virus in Houston families, 1976, J. Hyg. (Camb.) 86:303–313.

    Article  CAS  Google Scholar 

  • Tateno, I., Suzuki, S., Nakamura, S., et al., 1963, Etiology and seasonal incidence of acute nonbacterial respiratory infections in adults with emphasis on influenza, Jpn. J. Exp. Med. 33:159.

    PubMed  CAS  Google Scholar 

  • Taylor, R., Nemaia, H., Tukuitonga, C., et al., 1985, An epidemic of influenza in the population of Niue, J. Med. Virol. 16:127–136.

    Article  PubMed  CAS  Google Scholar 

  • Tillett, H. E., and Spencer, I.-L., 1982, Influenza surveillance in England and Wales using routine statistics, J. Hyg (Camb.) 88:83–94.

    Article  CAS  Google Scholar 

  • Troisi, C. L., and Monto, A. S., 1981, Comparison of enzyme-linked immunosorbent assay and hemagglutination inhibition in a seroepidemiological study of influenza type C infection, J. Clin. Microbiol. 14:515–521.

    Google Scholar 

  • Van Voris, L. P., Belshe, R. B., and Shaffer, J. L., 1982, Nosocomial influenza B virus infection in the elderly, Ann. Intern. Med. 96:153–158.

    PubMed  Google Scholar 

  • Velazco, J. G., Couch, R. B., Six, H. R., et al., 1983, Surveillance of influenza in Houston, Texas, USA: Gradual transition from A/Victoria/75 (H3N2) to A/Texas/77 (H3N2) predominance and antigenic characterization of “intermediate” strains, Bull. WHO 61:345–352.

    PubMed  CAS  Google Scholar 

  • Verhoeyen, M., Fang, R., Min Jou, W., et al., 1980, Antigenic drift between the haemagglutinin of the Hong Kong influenza strains A/Aichi/2/68 and A/Victoria/3/75, Nature 286:771–776.

    Article  PubMed  CAS  Google Scholar 

  • von Heise, R., Stelzner, A., Urbach, H., et al., 1976, Blood group affiliation of positive influenza A2 sera, Z. Ges. Hyg. 22:229–231.

    CAS  Google Scholar 

  • Watkins, I. J., Tills, D., and Health, R. B., 1975, Studies of the genetic susceptibility of individuals to infection with influenza viruses, Humangenetik 30:75–79.

    Article  Google Scholar 

  • Webster, R. G., and Berton, M. T., 1981, Analysis of antigenic drift in the haemagglutinin molecule of influenza B virus with monoclonal antibodies, J. Gen. Virol. 54:243–251.

    Article  PubMed  CAS  Google Scholar 

  • Welliver, R. C., Cherry, J. D., Boyer, K. M., et al., 1979, Sales of nonprescription cold remedies: A unique method of influenza surveillance, Pediatr. Res. 13:1015–1017.

    Article  PubMed  CAS  Google Scholar 

  • Whittaker, R. G., and Underwood, P. A., 1980, A mechanism for influenza subtype disappearance, Med. Hypotheses 6:997–1008.

    Article  PubMed  CAS  Google Scholar 

  • Widelock, D., Schaeffer, M., and Millian, S. J., 1965, Surveillance of infectious disease by serologic methods. I. Asian influenza, 1957–1964, Am. J. Public Health. 55:578–586.

    Article  CAS  Google Scholar 

  • Wiley, D. C., Wilson, I. A., and Skehel, J. J., 1981, Structural identification of the antibody binding sites of Hong Kong influenza hemagglutinin and their involvement in antigenic variation, Nature 289:373–378.

    Article  PubMed  CAS  Google Scholar 

  • Wright, P. F., Bryant, J. D., and Karzon, D. T., 1980, Comparison of influenza B/Hong Kong virus infections among infants, children, and young adults, J. Infect. Dis. 141:430–435.

    Article  PubMed  CAS  Google Scholar 

  • Yamane, N., Arikawa, J., Odagiri, T., et al., 1978, Isolation of three different influenza A viruses from an individual after probable double infection with H3N2 and H1N1 viruses, Jpn. J. Med. Sci. Biol. 31:431–434.

    PubMed  CAS  Google Scholar 

  • Young, J. F., and Palese, P., 1979, Evolution of human influenza A viruses in nature: Recombination contributes to genetic variation of H1N1 strains, Proc. Natl. Acad. Sci. U.S.A. 76:6647–6651.

    Google Scholar 

  • Zhdanov, V. M., and Ritova, V. V., 1962, Seasonal fluctuations in reactivity to live influenza vaccines, Vest. Akad. Med. Nauh SSR 17:3–5.

    Google Scholar 

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  1. Mount Sinai School of Medicine, City University of New York, New York, New York, USA

    Edwin D. Kilbourne M.D. (Distinguished Service Professor)

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Kilbourne, E.D. (1987). The Epidemiology of Influenza. In: Influenza. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5239-6_10

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