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Genetic Aspects of the Hypermobility Syndrome

  • Chapter
Hypermobility of Joints

Abstract

The term hypermobility syndrome (HMS) was coined to denote the presence of rheumatic symptoms with generalised joint laxity, in the absence of any demonstrable systemic rheumatic disease (Kirk et al. 1967). Of 9275 consecutive patients attending the rheumatology clinic at Guy’s Hospital, 2% were diagnosed as suffering from HMS. Of these, 85% were female (see Chap. 6). A similar prevalence (1.7%) has been seen among 690 new referrals to a paediatric rheumatology centre (Ansell 1972).

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Author information

Authors and Affiliations

  1. MRC Research Unit for Inherited Skeletal Disorders, Medical School and Groot Schuur Hospital, University of Cape Town, South Africa

    Peter Beighton MD, PhD, FRCP, DCH (Professor of Human Genetics and Director)

  2. Rheumatology Unit, Division of Medicine, United Medical and Dental Schools, Guy’s Hospital, SE1 9RT, London, UK

    Rodney Grahame MD, FRCP, FACP (Consultant Rheumatologist)

  3. Royal Bath Hospital, University of Leeds, and Clinical Pharmacology Unit (Rheumatism Research), HG1 2PS, Harrogate, UK

    Howard Bird MD, MRCP (Senior Lecturer and Consultant Rheumatologist)

Authors
  1. Peter Beighton MD, PhD, FRCP, DCH
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  2. Rodney Grahame MD, FRCP, FACP
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  3. Howard Bird MD, MRCP
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Editor information

Editors and Affiliations

  1. Rheumatology Unit, Division of Medicine, United Medical and Dental Schools, Guy’s Hospital, SE1 9RT, London, UK

    Rodney Grahame MD, FRCP, FACP (Consultant Rheumatologist) (Consultant Rheumatologist)

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© 1989 Springer-Verlag Berlin Heidelberg

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Beighton, P., Grahame, R., Bird, H. (1989). Genetic Aspects of the Hypermobility Syndrome. In: Grahame, R. (eds) Hypermobility of Joints. Springer, London. https://doi.org/10.1007/978-1-4471-3900-3_5

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  • DOI: https://doi.org/10.1007/978-1-4471-3900-3_5

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-3902-7

  • Online ISBN: 978-1-4471-3900-3

  • eBook Packages: Springer Book Archive

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