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Various Vertigo Syndromes

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Vertigo and Dizziness

Abstract

Here vertigo and dizziness in childhood are described first. The most frequent syndrome is benign paroxysmal vertigo of childhood, a form of vestibular migraine. Benign paroxysmal positional vertigo, Menière’s disease, vestibular neuritis, perilymph fistula, bilateral vestibulopathy, and central vestibular syndromes also occur in childhood.

This part also includes

  • Drug-induced vertigo

  • Cervicogenic vertigo

  • Episodic ataxias

  • Motion sickness (clinical aspects and pathogenesis, course, prophylaxis, and therapy)

  • Visual height intolerance and fear of heights (acrophobia)

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References

  • Abu-Arafeh I, Russel G. Paroxysmal vertigo as a migraine equivalent in children: a population-based study. Cephalalgia. 1995;15:22–5.

    Article  PubMed  CAS  Google Scholar 

  • Agras WS, Chapin HN, Oliveau DC. The natural history of phobia. Arch Gen Psychiatry. 1972;26:315–7.

    Article  PubMed  CAS  Google Scholar 

  • Alvina K, Khodakhah K. The therapeutic mode of action of 4-aminopyridine in cerebellar ataxia. J Neurosci. 2010;30:7258–68.

    Article  PubMed  CAS  Google Scholar 

  • American Psychiatric Association. Diagnostic and statistical manual of mental disorders (DSM IV). 4th ed. Washington: American Psychiatric Association; 1994.

    Google Scholar 

  • Baier B, Winkenwerder E, Dieterich M. Vestibular migraine: effects of prophylactic therapy with various drugs. A retrospective study. J Neurol. 2009;256:426–42.

    Google Scholar 

  • Balatsouras DG, Kaberos A, Assimakopoulos D, Katotomichelakis M, Economou NC, Korres SG. Etiology of vertigo in children. Int J Pediatr Otorhinolaryngol. 2007;71:487–94.

    Article  PubMed  Google Scholar 

  • Basser LS. Benign paroxysmal vertigo of childhood. A variety of vestibular neuronitis. Brain. 1964;87:141–52.

    Article  PubMed  CAS  Google Scholar 

  • Bauer M, Huppert D, Brandt T. Fear of heights in ancient China. J Neurol. 2012;259:2223–5.

    Article  PubMed  Google Scholar 

  • Bertholon P, Chabrier S, Riant F, Tournier-Lasserve E, Peyron R. Episodic ataxia type 2: unusual aspects in clinical and genetic presentation. Special emphasis in childhood. J Neurol Neurosurg Psychiatry. 2010;80:1289–92.

    Article  Google Scholar 

  • Bickerstaff ER. Basilar artery migraine. Lancet. 1961;1:15–8.

    Article  Google Scholar 

  • Blakley BW, Gulati H. Identifying drugs that cause dizziness. Otolaryngology. 2008;37:11–5.

    Google Scholar 

  • Bles W, Kapteyn TS, Brandt T, Arnold F. The mechanism of physiological height vertigo: II. Posturography. Acta Otolaryngol (Stockh). 1980;89:534–40.

    Article  CAS  Google Scholar 

  • Bles W, Bos JE, Kruit H. Motion sickness. Curr Opin Neurol. 2000;13:19–25.

    Article  PubMed  CAS  Google Scholar 

  • Boldingh MI, Ljostad U, Mygland A, Monstad P. Vestibular sensitivity in vestibular migraine: VEMP’s and motion sickness susceptibility. Cephalalgia. 2011;31:1211–9.

    Article  PubMed  Google Scholar 

  • Brandt T. Optisch-vestibuläre Bewegungskrankheit, Höhenschwindel und klinische Schwindelformen. Fortschr Med. 1976;94:177–1188.

    Google Scholar 

  • Brandt T. Cervical vertigo – reality or fiction? Audiol Neurotol. 1996;1:187–96.

    Article  CAS  Google Scholar 

  • Brandt T, Bronstein AM. Cervical vertigo. J Neurol Neurosurg Psychiatry. 2001;71:8–12.

    Article  PubMed  CAS  Google Scholar 

  • Brandt T, Strupp M. Episodic ataxia type 1 and 2 (familial periodic ataxia/vertigo). Audiol Neurotol. 1997;2:373–83.

    Article  CAS  Google Scholar 

  • Brandt T, Wenzel D, Dichgans J. Die Entwicklung der visuellen Stabilisation des aufrechten Standes beim Kind: Ein Reifezeichen in der Kinderneurologie. Arch Psychiat Nervenkr. 1976;223:1–13.

    Article  PubMed  CAS  Google Scholar 

  • Brandt T, Arnold F, Bles W, Kapteyn TS. The mechanism of physiological height vertigo: I.Theoretical approach and psychophysics. Acta Otolaryngol (Stockh). 1980;89:513–23.

    Article  CAS  Google Scholar 

  • Brandt T, Benson J, Huppert D. What to call “non-phobic” fear of heights? Br J Psychiatry. 2012a;190:81. doi:10.1192/bjp190.1.81a.

    Google Scholar 

  • Brandt T, Strupp M, Huppert D. Height intolerance – an underrated threat. J Neurol. 2012b;259:759–60.

    Article  PubMed  Google Scholar 

  • Brown JJ, Baloh RW. Persistent mal de debarquement-syndrome: a motion-induced subjective disorder of balance. Am J Otolaryngol. 1987;8:219–22.

    Article  PubMed  CAS  Google Scholar 

  • Brunt ER, van Weerden TW. Familial paroxysmal kinesiogenic ataxia and continuous myokymia. Brain. 1990;113:1361–82.

    Article  PubMed  Google Scholar 

  • Cha YH. Mal de debarquement. Semin Neurol. 2009;29:520–7.

    Article  PubMed  Google Scholar 

  • Cha YH, Chakrapani S, Craig A, Baloh RW. Metabolic and functional connectivity changes in mal de debarquement syndrome. PLoS One. 2012;7:e49560.

    Article  PubMed  CAS  Google Scholar 

  • Cha YH, Cui Y, Baloh RW. Repetitive transcranial magnetic stimulation for mal de debarquement syndrome. Otol Neurotol. 2013;34:175–9.

    Article  PubMed  Google Scholar 

  • Cianfrone G, Pentangelo D, Cianfrone E, Mazzei F, Turchetta R, Orlando MP, et al. Pharmacological drugs inducing ototoxicity, vestibular symptoms and tinnitus: a reasoned and update guide. Eur Rev Med Pharmacol Sci. 2011;15:601–36.

    PubMed  CAS  Google Scholar 

  • Clark BC, Leporte A, Clark S, Hoffman RL, Quick A, Wilson TE, et al. Effects of persistent mal de debarquement syndrome on balance, psychological traits, and motor cortex excitability. J Clin Neurosci. 2013;20:446–50.

    Article  PubMed  Google Scholar 

  • Coelho CM, Wallis G. Deconstructing acrophobia: physiological and psychological precursors to developing a fear of heights. Depress Anxiety. 2010;27:864–70.

    Article  PubMed  Google Scholar 

  • Cuomo-Granston A, Drummond PD. Migraine and motion sickness: what is the link? Prog Neurobiol. 2010;91:300–12.

    Article  PubMed  Google Scholar 

  • Curtis GC, Magee WJ, Eaton WW, Wittchen HU. Specific fears and phobias. Epidemiology and classification. Br J Psychiatry. 1998;173:212–7.

    Article  PubMed  CAS  Google Scholar 

  • Dai M, Raphan T, Cohen B. Labyrinthine lesions and motion sickness susceptibility. Exp Brain Res. 2007;178:477–87.

    Article  Google Scholar 

  • De Jong IMBV, Bles W. Cervical dizziness and ataxia. In: Bles W, Brandt T, editors. Disorders of posture and gait. Amsterdam/New York/Oxford: Elsevier; 1986. p. 185–206.

    Google Scholar 

  • De Quervain DJ, Bentz D, Michael T, Bolt OC, Wiederhold BK, Margraf J, et al. Glucocorticoids enhance extinction-based psychotherapy. Proc Natl Acad Sci. 2011;108:6621–5.

    Article  PubMed  Google Scholar 

  • Depla MFIA, ten Have ML, van Balkom AJLM, de Graf R. Specific fears and phobias in the ­general population: results from the Netherlands Mental Health Survey and Incidence Study (NEMESIS). Soc Psychiatry Psychiatr Epidemiol. 2008;43:200–8.

    Article  PubMed  Google Scholar 

  • Dichgans J, Brandt T. Optokinetic motion-sickness and pseudo-coriolis effects induced by moving visual stimuli. Acta Otolaryngol. 1973;76:339–48.

    Article  PubMed  CAS  Google Scholar 

  • Dichgans J, Brandt T. Visual-vestibular interaction: effects of self-motion perception and postural control. In: Held R, Leibowitz HW, Teuber HL, editors. Handbook of Sensory Physiology, Perception, vol. III. Berlin/Heidelberg/New York: Springer; 1978. p. 755–804.

    Google Scholar 

  • Dieterich M, Pöllmann W, Pfaffenrath V. Cervicogenic headache: electronystagmography, ­perception of verticality and posturography in patients before and after C2-blockade. Cephalalgia. 1993;13:285–8.

    Article  PubMed  CAS  Google Scholar 

  • Erbek SH, Erbek SS, Yilmaz I, Topal O, Ozgirgin N, Ozluoglu LN, et al. Vertigo in childhood: a clinical experience. Int J Pediatr Otorhinolaryngol. 2006;70:1547–54.

    Article  PubMed  Google Scholar 

  • Evans RW, Marcus D, Furman JM. Motion sickness and migraine. Headache. 2007;47:607–10.

    Article  PubMed  Google Scholar 

  • Gil A, Nachum Z, Tal D, Shupak A. A comparison of cinnarizine and transdermal scopolamine for the prevention of seasickness in a naval crew: a double-blind, randomized, crossover study. Clin Neuropharmacol. 2012;35:37–9.

    Article  PubMed  CAS  Google Scholar 

  • Golding IF, Markey HM, Stott IR. The effects of motion direction, body axis, and posture on motion sickness induced by low frequency linear oscillation. Aviat Space Environ Med. 1995;66:1046–51.

    PubMed  CAS  Google Scholar 

  • Griggs RC, Nutt JG. Episodic ataxias as channelopathies. Ann Neurol. 1995;37:285–7.

    Article  PubMed  CAS  Google Scholar 

  • Griggs RC, Moxley RT, Lafrance RA, McQuillen J. Hereditary paroxysmal ataxia: response to acetazolamide. Neurology. 1978;28:1259–64.

    Article  PubMed  CAS  Google Scholar 

  • Holtmann S, Reiman V, Schöps P. Clinical significance of cervico-ocular reactions. Laryngorhinootologie. 1993;72:306–10.

    Article  PubMed  CAS  Google Scholar 

  • Huppert D, Strupp M, Mückter H, Brandt T. Which medication do I need to manage dizzy patients? Acta Otolaryngol. 2011;131:228–41.

    Article  PubMed  Google Scholar 

  • Huppert D, Grill E, Brandt T. Down on heights? One in three has visual height intolerance. J Neurol. 2013;260:597–604.

    Article  PubMed  Google Scholar 

  • Jahn K, Zwergal A, Strupp M, Brandt T. Schwindel im Kindesalter. Nervenheilkunde. 2009;28:47–52.

    Google Scholar 

  • Jahn K, Langhagen T, Schroeder AS, Heinen F. Vertigo and dizziness in childhood – update on diagnosis and treatment. Neuropediatrics. 2011;42:129–34.

    Article  PubMed  CAS  Google Scholar 

  • Jen JC. Hereditary episodic ataxias. Ann N Y Acad Sci. 2008;1142:250–3.

    Article  PubMed  CAS  Google Scholar 

  • Jen J, Kim GW, Baloh RW. Clinical spectrum of episodic ataxia type 2. Neurology. 2004;62:17–22.

    Article  PubMed  CAS  Google Scholar 

  • Jen JC, Graves TD, Hess EJ, Hanna MG, Griggs RC, Baloh RW. Primary episodic ataxias: diagnosis, pathogenesis and treatment. Brain. 2007;130:2484–93.

    Article  PubMed  CAS  Google Scholar 

  • Kanaan AA, Raad RA, Hourani RG, Zaytoun GM. Bilateral superior semicircular canal dehiscence in a child with sensorineural hearing loss and without vestibular symptoms. Int J Pediatr Otorhinolaryngol. 2011;75:877–9.

    Article  PubMed  Google Scholar 

  • Knox GW, Woodard D, Chelen W, Ferguson R, Johnson L. Phenytoin for motion sickness: clinical evaluation. Laryngoscope. 1994;1994:935–9.

    Google Scholar 

  • Krams B, Echenne B, Leydet J, Rivier F, Roubertie A. Benign paroxysmal vertigo of childhood: long-term outcome. Cephalalgia. 2011;31:439–43.

    Article  PubMed  Google Scholar 

  • Lanzi G, Balottin U, Fazzi E, Tagliasacchi M, Manfrin M, Mira E. Benign paroxysmal vertigo of childhood: a long-term follow-up. Cephalalgia. 1994;14:458–60.

    Article  PubMed  CAS  Google Scholar 

  • Lee GS, Zhou G, Poe D, Kenna M, Amin M, Ohlms L, et al. Clinical experience in diagnosis and management of superior semicircular canal dehiscence in children. Laryngoscope. 2011;121:2256–61.

    Article  PubMed  Google Scholar 

  • Macke A, LePorte A, Clark BC. Social, societal, and economic burden of mal de debarquement syndrome. J Neurol. 2012;259:1326–30.

    Article  PubMed  Google Scholar 

  • Moeller L, Lempert T. Mal de debarquement: pseudo-hallucinations from vestibular memory? J Neurol. 2007;254:813–5.

    Article  PubMed  Google Scholar 

  • Money KE. Motion sickness. Physiol Rev. 1970;50:1–39.

    PubMed  CAS  Google Scholar 

  • Murdin L, Golding J, Bronstein A. Managing motion sickness. BMJ. 2011;343:d7430.

    Article  PubMed  Google Scholar 

  • Murphy TP. Mal de debarquement syndrome: a forgotten entity? Otolaryngol Head Neck Surg. 1993;109:10–3.

    PubMed  CAS  Google Scholar 

  • Neuhauser H, Lempert T. Vertigo and dizziness related to migraine: a diagnostic challenge. Cephalalgia. 2004;24:83–91.

    Article  PubMed  CAS  Google Scholar 

  • Niemensivu R, Kentala E, Wiener-Vacher S, Pyykko I. Evaluation of vertiginous children. Eur Arch Otorhinolaryngol. 2007;264:1129–35.

    Article  PubMed  Google Scholar 

  • Noyes R, Clancy J, Hoenk PR, Slymen DJ. The prognosis of anxiety neurosis. Arch Gen Psychiatry. 1980;37:173–8.

    Article  PubMed  Google Scholar 

  • Probst T, Krafczyk S, Büchele W, Brandt T. Visuelle Prävention der Bewegungskrankheit im Auto. Arch Psychiat Nervenkr. 1982;231:409–21.

    Article  PubMed  CAS  Google Scholar 

  • Pull CB. Current status of virtual reality exposure therapy in anxiety disorders: editorial review. Curr Opin Psychiatry. 2005;18:7–14.

    PubMed  Google Scholar 

  • Rascol O, Hain TC, Brefel C, Benazet M, Clanet M, Montastruc JL. Antivertigo medications and drug-induced vertigo. A pharmacological review. Drugs. 1995;50:777–91.

    Article  PubMed  CAS  Google Scholar 

  • Reason JT. Motion sickness adaptation: a neural mismatch model. J R Soc Med. 1978;71:819–29.

    PubMed  CAS  Google Scholar 

  • Riina N, Ilmari P, Kentala E. Vertigo and imbalance in children: a retrospective study in a Helsinki University otorhinolaryngology clinic. Arch Otolaryngol Head Neck Surg. 2005;131:996–1000.

    Article  PubMed  Google Scholar 

  • Ritter B. Treatment of acrophobia with contact desensibilisation. Behav Res Ther. 1969;7:41–5.

    Article  PubMed  CAS  Google Scholar 

  • Russel G, Abu-Arafeh I. Paroxysmal vertigo in children- an epidemiological study. Int J Pediatr Otorhinolaryngol. 1999;49(1):105–7.

    Article  Google Scholar 

  • Salassa JR, Zapala DA. Love and fear of heights: the pathophysiology and psychology of height imbalance. Wilderness Environ Med. 2009;20:378–82.

    Article  PubMed  Google Scholar 

  • Shoair OA, Nyandege AN, Slattum PW. Medication-related dizziness in the oder adult. Otolaryngol Clin North Am. 2011;44:455–71.

    Article  PubMed  Google Scholar 

  • Shupak A, Gordon CR. Motion sickness: advances in pathogenesis, prediction, prevention, and treatment. Aviat Space Environ Med. 2006;77:1213–23.

    PubMed  Google Scholar 

  • Spinks AB, Wasiak J. Scopolamine (hyoscine) for preventing and treating motion sickness. Cochrane Database Syst Rev. 2011;6:CD002851.

    Google Scholar 

  • Strupp M, Kalla R, Dichgans M, Freilinger T, Glasauer S, Brandt T. Treatment of episodic ataxia type 2 with the potassium channel blocker 4-aminopyridine. Neurology. 2004;62:1623–5.

    Article  PubMed  CAS  Google Scholar 

  • Strupp M, Zwergal A, Brandt T. Episodic ataxia type 2. Neurotherapeutics. 2007;4:267–73.

    Article  PubMed  CAS  Google Scholar 

  • Strupp M, Kalla R, Claassen J, Adrion C, Mansmann U, Klopstock T, et al. A randomized trial of 4-aminopyridine in EA2 and related familial episodic ataxias. Neurology. 2011;77:269–75.

    Article  PubMed  CAS  Google Scholar 

  • Tinetti ME. Preventing falls in elderly persons. N Engl J Med. 2002;348:42–9.

    Article  Google Scholar 

  • Walk RD, Gibson EJ, Tighe TJ. Behaviour of light- and dark-raised rats on a visual cliff. Science. 1957;126:80–1.

    Article  PubMed  CAS  Google Scholar 

  • Wolpe J. Psychotherapy by reciprocal inhibition. Stanford: Stanford University Press; 1958.

    Google Scholar 

  • Wood CD, Graybiel A. Evaluation of antimotion sickness drugs: a new effective remedy revealed. Aerosp Med. 1970;41:932–3.

    PubMed  CAS  Google Scholar 

  • Wood CD, Graybiel A, Kennedy RS. Comparison of effectiveness of some antimotion sickness drugs using recommended and larger than recommended doses as tested in the slow rotation room. Aerospace Med. 1966;37:259–62.

    PubMed  CAS  Google Scholar 

  • Zhang D, Fan Z, Han Y, Wang M, Xu L, Luo J, et al. Benign paroxysmal vertigo of childhood: diagnostic value of vestibular test and high stimulus rate auditory brainstem response test. Int J Pediatr Otorhinolaryngol. 2012;76:107–10.

    Article  PubMed  Google Scholar 

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Brandt, T., Dieterich, M., Strupp, M. (2013). Various Vertigo Syndromes. In: Vertigo and Dizziness. Springer, London. https://doi.org/10.1007/978-0-85729-591-0_6

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