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Pancreatic Cancer 

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  1. Open Access 16-05-2024 | Pancreatic Cancer | Online First

    The Spanish Familial Pancreatic Cancer Registry (PANGENFAM): a decade follow-up of individuals at high-risk for pancreatic cancer

    The Spanish Familial Pancreatic Cancer Registry (PANGENFAM) was established in 2009 and aims to characterize the genotype and phenotype of familial pancreatic cancer (FPC). Furthermore, an early detection screening program for pancreatic ductal …

  2. Open Access 24-02-2024 | Chronic Pancreatitis | OriginalPaper

    A resected case of pancreatic head cancer developing 40 years after lateral pancreaticojejunostomy for chronic pancreatitis

    A 72-year-old male patient presented to our department complaining of with upper abdominal pain and jaundice. He had a history of a side-to-side pancreaticojejunostomy performed 40 years previously for chronic pancreatitis. A diagnostic workup …

  3. 09-03-2024 | Pancreatectomy | OriginalPaper

    Refractory postoperative pancreatic fistula following laparoscopic distal pancreatectomy for pancreatic cancer caused by incomplete pancreas divisum: a case report

    Pancreas divisum (PD) represents a prevalent congenital pancreatic variant, typically arising from the failure of fusion between the ventral and dorsal pancreatic ducts. This condition is frequently associated with recurrent pancreatitis. We …

  4. Open Access 15-04-2024 | Metastasis | Online First

    Establishment, characterization, and biobanking of 36 pancreatic cancer organoids: prediction of metastasis in resectable pancreatic cancer

    Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignancies with a propensity for early metastatic spread [ 1 ]. Approximately 80% of PDAC patients are diagnosed at an advanced stage with a dismal prognosis [ 2 , 3 ].

  5. Open Access 25-05-2024 | Pancreatic Cancer | Online First

    Review of the cost-effectiveness of surveillance for hereditary pancreatic cancer

    Individuals with hereditary pancreatic cancer risk include high risk individuals (HRIs) with germline genetic susceptibility to pancreatic cancer (PC) and/or a strong family history of PC. Previously, studies have shown that PC surveillance in …

  6. Open Access 24-05-2024 | Pancreatic Cancer | Online First

    Minorities Face Delays to Pancreatic Cancer Treatment Regardless of Diagnosis Setting

  7. 26-04-2024 | Pancreatic Cancer | ReviewPaper

    The Role of Neoadjuvant and Adjuvant Chemotherapy in Pancreatic Cancer

    Pancreatic cancer is an aggressive malignancy. Recurrences are very high despite high-quality surgery necessitating adjuvant therapy. The evolution of adjuvant therapy took several decades and gradually evolved from single-agent chemotherapy to …

  8. 11-05-2024 | Pancreatic Cancer | Online First

    Familial and hereditary pancreatic cancer in Japan

    As in Western countries, familial pancreatic cancer accounts for 5–7% of pancreatic cancer (PC) in Japan. Opportunities for diagnosing hereditary pancreatic cancer (HPC) are increasing owing to the coverage of companion diagnostics and cancer

  9. Open Access 01-12-2024 | Pancreatic Cancer | OriginalPaper

    Keratin 17 modulates the immune topography of pancreatic cancer

    Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal forms of cancer, not only because it is often not diagnosed until after it has reached advanced stage and is intrinsically resistant to Gemcitabine and 5-fluorouracil based …

  10. 11-05-2024 | Pancreatic Cancer | Online First

    Expanding access to genetic testing for pancreatic cancer

    Among individuals with pancreatic ductal adenocarcinoma (PDAC) 5–10% have a pathogenic germline variant (PGV) in a PDAC susceptibility gene. Guidelines recommend genetic testing among all individuals with PDAC. Additionally, at-risk relatives of …

  11. 18-05-2024 | Pancreatic Cancer | Online First

    Early detection of pancreatic cancer in the era of precision medicine

    Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related mortality and it is often diagnosed at advanced stages due to non-specific clinical presentation. Disease detection at localized disease stage followed by …

  12. 24-05-2024 | Radiotherapy | Online First

    Adjuvant Chemotherapy With or Without Radiotherapy for Resected Pancreatic Cancer After Multiagent Neoadjuvant Chemotherapy

  13. 22-04-2024 | Pancreatic Cancer | OriginalPaper

    Management of malignant Gastric Outlet Obstruction (mGOO) due to pancreatic cancer in the era of EUS-Gastrojejunostomy: an international practice survey and case vignette study by Pancreas 2000 from the European Pancreatic Club

  14. 23-05-2024 | Pancreatitis | Online First

    Hidden in plain sight: commonly missed early signs of pancreatic cancer on CT

    Pancreatic ductal adenocarcinoma (PDAC) has poor prognosis mostly due to the advanced stage at which disease is diagnosed. Early detection of disease at a resectable stage is, therefore, critical for improving outcomes of patients. Prior studies …

  15. 01-05-2024 | Pancreatic Cancer | EditorialNotes

    Novel concepts for surgical treatment of pancreatic cancer

  16. 03-05-2024 | Pancreatic Cancer | Online First

    Harnessing Plant Flavonoids to Fight Pancreatic Cancer

    Pancreatic cancer is an exceptionally lethal malignancy for which mortality closely parallels incidence [ 1 ]. Due to the lack of early symptoms coupled with the unavailability of early efficient non-invasive screening and diagnostic markers …

  17. 10-05-2024 | Pancreatic Cancer | Online First

    Zinc supplementation for dysgeusia in patients with unresectable pancreatic cancer

    Pancreatic cancer (PC) has one of the most dismal prognoses among all solid cancers, with a 5-year overall survival rate of 12% [ 1 ]. Early diagnosis of PC remains challenging [ 2 – 4 ], and approximately 80% of patients with PC are diagnosed …

  18. 19-04-2024 | Autoimmune Pancreatitis | Online First

    Quantitative MR imaging biomarkers for distinguishing inflammatory pancreatic mass and pancreatic cancer—a systematic review and meta-analysis

    Inflammatory pancreatic masses (IPM) primarily encompass mass-forming pancreatitis (MFP) and autoimmune pancreatitis (AIP). The imaging appearance of both tumors mimics pancreatic cancer (PC) [ 1 , 2 ]. However, PC is a highly fatal disease and …

  19. Open Access 21-05-2024 | Metastasis | Online First

    Concomitant metastatic head-and-neck cancer and pancreatic cancer assessed by αvβ6-integrin PET/CT using 68Ga-Trivehexin: incidental detection of a brain metastasis

  20. Open Access 01-12-2024 | Pancreatectomy | OriginalPaper

    Adjuvant chemotherapy omission after pancreatic cancer resection: a French nationwide study

    Despite tremendous efforts to improve prognosis, pancreatic ductal adenocarcinoma (PDAC) is expected to be the second leading cause of cancer [ 1 ]. After curative resection, adjuvant chemotherapy (AC) can significantly improve disease-free and …

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