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Circulatory Disease Hypertension

Hypertension

Open Access Hypertension Review

Does intestinal permeability have a role in hypertension?

Evidence from animal models supports the presence of intestinal barrier dysfunction in hypertension, but what is the evidence in humans? Could hypertension increase gut permeability, or vice versa?

Editor's Choice

How neuroimmunology affects the heart

Open Access Circulatory Disease Review

What is the brain’s involvement in cardiovascular disease pathology? Evidence suggests that neuroimmune mechanisms may play a key role. 

Treating comorbid heart failure and hypertension

Open Access Heart Failure Review

Managing patients with acute or chronic HFpEF and concurrent hypertension is difficult. Make sure you're confident prescribing the optimal drug combination. 

What role does our diet play in hypertension?

Open Access Hypertension Review

Healthy, plant-based diets can be useful in preventing and treating hypertension. Incorporating evidence-based nutritional education into clinical care and society more broadly would help hypertension control. 

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Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Episode 3: Unravelling resistant hypertension

Why is it so difficult to diagnose and manage?

Resistant hypertension is a difficult to treat and often misunderstood phenomenon that continues to frustrate cardiologists. 

In this episode, Professors Morris Brown and Bryan Williams debate the causes of resistant hypertension and explore novel treatment options.

Prof. Morris Brown
Prof. Bryan Williams

Case Studies

Unique presentation of memantine overdose

Open Access Medical Side Effect Case Study

Hypertensive urgency and echolalia were the most striking symptoms of memantine overdose in an elderly man with mild dementia and hypertension. Early medication review with caregivers of people with dementia is key.

Hypertension, proteinuria, and hypercalciuria in a previously healthy 3-year-old

Open Access Hypertension Case Study

A panel of experts examine the differential diagnosis for secondary hypertension in a young child, and the eventual diagnosis and management of generalized arterial calcification in infants.

Aortic isthmus massive calcifications causing secondary hypertension

Open Access Hypertension Case Study

A 63-year-old woman presented with multiple, short-succession hospital admissions for heart failure and sustained hypertension despite intensive therapy. A diagnosis of a secondary hyperaldosteronism was made, resulting from renal hypoperfusion due to narrowing of the thoracic aorta by a huge calcified plaque, mimicking an aortic coarctation.

Current Reviews

Novel inhaled pulmonary vasodilators in adult cardiac surgery: a scoping review

Milrinone Review Article/Brief Review

Our methodology was informed by the “PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation.” 14 This scoping review is in adherence with PRISMA guidelines. The review protocol was preregistered with the Open Science Framework …

Management of Portal Hypertension in the Older Patient

WHO declared the commencement of aging of global population. Currently, people above the age of 60 years account for 1 billion of the world’s population, and the number is expected to increase to 2.1 billion by 2050 [ 1 ]. According to WHO Global …

Association Between Preeclampsia and Blood Pressure in Offspring: A Systematic Review and Meta-Analysis

Pre-Eclampsia Preeclampsia (VD Garovic and AG Kattah, Section Editors)

Preeclampsia is a multisystem pregnancy disorder defined as a common pregnancy complication with a new onset of hypertension after 20 weeks of gestation, often accompanied by proteinuria or other systemic diseases [ 1 ]. The overall estimate is …

Blood Pressure Management in Intracerebral Haemorrhage: when, how much, and for how long?

Open Access Stroke Review

Intracerebral haemorrhage (ICH) accounts for 15–30% of stroke and has high 30-day mortality of approximately 40%, with only 12 to 39% of patients achieving independent functional recovery [ 1 ]. While there have been many recent advances in …

Webinar | 16-05-2023 | 17:30 (CEST)

Keynote webinar | Spotlight on cardio-oncology

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Prof. Rudolf de Boer
Prof. Lorenz Lehmann
Dr. Teresa Lopéz Fernández
Developed by: Springer Medicine

Further Reading

Blood pressure monitoring in elderly migraineurs starting an anti-CGRP monoclonal antibody: a real-world prospective study

Open Access Fremanezumab Original Article

Migraine is considered the second-highest cause of years lived with disability in the young-adult population [ 1 ]. While it is less prevalent among older individuals, the presence of comorbidities and the use of multiple medications can contribute …

Prevalence, Clustering, and Current Management of Cardiovascular Risk Factors Upon First Referral to Hypertension Specialists: the APPROACH Study

Open Access Hypertension Original article

With nearly 18 million deaths annually, cardiovascular disease (CVD) is the leading cause of premature mortality for non-communicable diseases (NCDs) worldwide, far exceeding the burden associated with the next most common NCDs, namely cancer …

High body mass index and triglyceride levels at health checkups increase the risk of new-onset chronic kidney disease and worsening renal function: the TAMA MED Project-CKD

Open Access Chronic Kidney Disease Original article

Chronic kidney disease (CKD) is an urgent issue that needs to be addressed as the number of patients requiring dialysis is increasing worldwide. It is a serious risk factor for cardiovascular diseases and has a significant impact on the health of …

Isometric Exercise Training and Arterial Hypertension: An Updated Review

Open Access Arterial Hypertension Review Article

Hypertension is recognised as a leading attributable risk factor for cardiovascular disease and premature mortality. Global initiatives towards the prevention and treatment of arterial hypertension are centred around non-pharmacological lifestyle …