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Dementia 

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  1. Open Access 28-05-2024 | Dementia | Online First

    Heightened Prevalence of Common Hospital-Treated Infections Preceding Dementia Diagnosis with Accelerated Dementia Onset after Influenza

    Approximately 55 million people worldwide suffer from dementia. Due to sociodemographic changes, the incidence is increasing, particularly in low- and middle-income countries ( 1 ). The most common type of dementia is Alzheimer’s disease (AD) …

  2. Open Access 01-12-2024 | Dementia | OriginalPaper

    Post-diagnostic support for persons with young-onset dementia – a retrospective analysis based on data from the Swedish dementia registry SveDem

  3. Open Access 08-05-2024 | Dementia | Review

    Differentiating Prodromal Dementia with Lewy Bodies from Prodromal Alzheimer’s Disease: A Pragmatic Review for Clinicians

    Overlapping clinical phenotypes make diagnosis challenging in patients with mild cognitive impairment. What clinical and biological features can help characterize dementia with Lewy bodies versus Alzheimer's disease?

  4. 30-05-2024 | Vascular Dementia | Online First

    Hypercholesterolemia and the Increased Risk of Vascular Dementia: a Cholesterol Perspective

    Vascular dementia (VaD) is a progressive disease that impairs memory and cognition, a group of syndromes caused by vascular lesions in the brain. Individuals with VaD may suffer from forgetfulness, mental retardation, depression and anxiety …

  5. 01-05-2024 | Dementia | News

    ADR-related hospitalisation in elderly patients with dementia

  6. Open Access 01-12-2024 | COVID-19 Vaccination | OriginalPaper

    Modeling mortality prediction in older adults with dementia receiving COVID-19 vaccination

    The coronavirus disease 2019 (COVID-19) pandemic created immense challenges for older adults with Alzheimer's disease and related dementias (ADRD) [ 1 , 2 ]. These progressive neurological conditions involve impairment of cognitive functions …

  7. 10-05-2024 | Dementia | News | Article

    Antipsychotic use in dementia has broad adverse outcomes

    Antipsychotic treatment of behavioral and psychological symptoms in patients with dementia is known to increase risk of stroke and death, but new findings indicate a broader range of adverse outcomes.

  8. 04-05-2024 | Dementia | Online First

    Updates in Fluid, Tissue, and Imaging Biomarkers for Dementia with Lewy Bodies and Implications for Biologically Based Disease Definitions

    Dementia with Lewy bodies (DLB) is a neurodegenerative dementia characterized by progressive cognitive decline with a mix of parkinsonism,

  9. Open Access 01-12-2024 | Dementia | OriginalPaper

    Plasma trimethylamine N-oxide (TMAO): associations with cognition, neuroimaging, and dementia

    Dementia is a leading cause of disability and dependency among older adults, with approximately 10 million new diagnoses per year worldwide [ 1 ]. In the absence of definitive curative treatments, there has been a growing interest in identifying …

  10. Open Access 01-12-2024 | Dementia | ReviewPaper

    Association between chronic pain and dementia: a systematic review and meta-analysis

    Chronic pain (CP) is defined by the International Association for the Study of Pain (IASP) as pain that lasts for more than 3 months (Turk et al. 2011 ; International Association for the Study of Pain 1986 ). It affects over 30% of people worldwide …

  11. Open Access 01-12-2024 | Dementia | OriginalPaper

    Extreme behavioural and psychological symptoms of dementia: a case study

    Dementia, is also known as a Major Neurocognitive disorder, and is defined by a significant decline in cognitive function which impairs capacity to perform everyday activities independently [ 1 ]. Dementia is typically diagnosed based on a …

  12. Open Access 01-12-2024 | Dementia | ReviewPaper

    The relationship between diabetes and the dementia risk: a meta-analysis

    Diabetes, a prevalent chronic metabolic disorder, is marked by elevated blood sugar levels from hypoinsulinism or insulin resistance [ 1 ]. The International Diabetes Federation (IDF) highlights a significant increase in global diabetes cases—from …

  13. Open Access 01-12-2024 | Dementia | OriginalPaper

    Specification curve analysis to identify heterogeneity in risk factors for dementia: findings from the UK Biobank

    In 2020, the Lancet Commission Report highlighted 12 potentially correlated and modifiable risk factors as targets for potential dementia prevention, intervention, and care for different age groups: education, hearing loss, traumatic brain injury …

  14. 26-05-2024 | Hyponatremia | Online First

    Senna intoxication as a cause of extrapontine myelinolysis mimicking rapidly progressive dementia: a case description

  15. Open Access 01-12-2024 | Dementia | OriginalPaper

    Addition of inflammation-related biomarkers to the CAIDE model for risk prediction of all-cause dementia, Alzheimer’s disease and vascular dementia in a prospective study

    The number of dementia cases worldwide is continuously rising and is projected to double nearly every 20 years [ 1 ]. With the approval of Aduhelm , Leqembi, and Donanemab as the first effective treatments against Alzheimer’s disease (AD) by the …

  16. Open Access 01-12-2024 | Dementia | OriginalPaper

    Gendered differences in the prevalence and associated factors of dementia in Ghana: a cross-sectional survey

    Over the past three decades, there has been a significant shift in the causes of mortality, with non-communicable diseases [NCDs] including dementia accounting for a higher burden of deaths and frailty. Dementia, an NCD, is “a syndrome, usually of …

  17. Open Access 09-04-2024 | Methotrexate | OriginalPaper

    Methotrexate and the Risk of Dementia: A Two-Sample Mendelian Randomization Study

    Methotrexate, the most common disease-modifying antirheumatic drug, is the cornerstone of therapy for many autoimmune diseases and is commonly used in the treatment of rheumatoid arthritis (RA), osteoarthritis, and psoriasis [ 1 – 3 ]. Several …

  18. 14-05-2024 | Dementia | Online First

    Protective Effects of β-Blockers on Bone in Older Adults with Dementia

    Increased β-adrenergic receptor activity has been hypothesized to cause bone loss in those with dementia. We investigated the effect of long-term β-blocker use on rate of bone loss in older adults with dementia. We used a linear mixed-effects …

  19. Open Access 17-05-2024 | Frontotemporal Dementia | Online First

    Profiles of motivational impairment and their relationship to functional decline in frontotemporal dementia

    Motivational disturbances are pervasive in frontotemporal dementia (FTD) and impact negatively on everyday functioning. Despite mounting evidence of anhedonia in FTD, it remains unclear how such changes fit within the broader motivational symptom …

  20. Open Access 07-05-2024 | Dementia | Online First

    Risk of Dementia in Korean Vietnam War Veterans

    M ilitary soldiers encounter severe risks while performing their duties on battlefields. Numerous studies have reported that war veterans experience a multitude of health consequences resulting from exposure to environmental hazards, such as toxic …

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