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Obstructive Lung Diseases Chronic Obstructive Lung Disease

Chronic Obstructive Lung Disease

NOTUS confirms benefit of dupilumab for COPD

Add-on subcutaneous dupilumab is associated with fewer exacerbations and better lung function than placebo in people with COPD and type 2 inflammation.

Editor's Choice

Type 2 inflammation worsens lung function decline

07-03-2024 Respiratory Medicine News

The presence of type 2 inflammation is associated with accelerated lung function decline in people with chronic airway disease.

Caution needed when prescribing gabapentinoids in people with COPD

Gabapentinoid use by patients with chronic obstructive pulmonary disease for epilepsy, neuropathic pain, or other chronic pain is associated with an increased risk for severe exacerbations.

Eosinophil-directed prednisolone for COPD exacerbations

Using blood eosinophil count to guide prednisolone treatment of COPD exacerbations does not lead to increased treatment failures versus standard, unguided care.

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Case Studies

Superior vena cava syndrome induced by COPD

Superior vena cava (SVC) syndrome occurs when the SVC is either partially or completely obstructed. In this case of an elderly patient with dyspnea, a thoracic CT showed SVC caused by lung hyperinflation due to chronic obstructive pulmonary disease. 

Recognizing exacerbations of COPD and managing underlying inflammation

This infographic provides an overview of how to recognize and manage exacerbations in patients with COPD and the overall impact of these exacerbations on patient care, along with insights from Dr. Nicola A. Hanania. Comorbidities associated with type 2 and neutrophilic inflammation are also outlined.

Supported by: Sanofi and Regeneron

Dr. Nicola A. Hanania
Developed by: Springer Healthcare

Current Reviews

Intraclass comparison of inhaled corticosteroids for the risk of pneumonia in chronic obstructive pulmonary airway disorder: a network meta-analysis and meta-regression

Fluticasone Review Article

Clinicians should consider dosage, body mass index, and exacerbation history while prescribing inhalational corticosteroids to mitigate the risk of pneumonia. Pharmacists should educate patients about the risk of pneumonia while dispensing …

Implications of Cardiopulmonary Risk for the Management of COPD: A Narrative Review

Chronic obstructive pulmonary disease (COPD) constitutes a major global health burden and is the third leading cause of death worldwide. A high proportion of patients with COPD have cardiovascular disease, but there is also evidence that COPD is a …

The role of vasculature and angiogenesis in respiratory diseases

Open Access Chronic Obstructive Lung Disease Review Paper

In European countries, nearly 10% of all hospital admissions are related to respiratory diseases, mainly chronic life-threatening diseases such as COPD, pulmonary hypertension, IPF or lung cancer. The contribution of blood vessels and angiogenesis …

Chronic Obstructive Pulmonary Disease in Heart Failure: Challenges in Diagnosis and Treatment for HFpEF and HFrEF

Chronic obstructive pulmonary disease (COPD) is one of the most prevalent comorbidities among patients with HF, especially in HF with preserved ejection fraction (HFpEF) [ 1 ]. Moreover, in patients where HF and COPD coexist, the prevalence of …

Infographic

This expert-led infographic explains how to recognize and manage COPD exacerbations and explores the impact of these exacerbations at the patient and physician level.

Supported by:
  • Sanofi and Regeneron
Developed by: Springer Healthcare

Further Reading

Cognitive complaints in patients with untreated obstructive sleep apnea versus patients with neurological and respiratory diseases: prevalence, severity and risk factors

Open Access Brain Tumor Epidemiology • Original Article

Obstructive Sleep Apnea (OSA) is a sleep disorder characterized by intermittent obstruction of the airway during sleep. OSA is associated with cognitive impairments as verified with neuropsychological testing [ 1 ]. Causes for cognitive impairments …

Long-term outcomes in patients with COPD treated with non-invasive ventilation for acute hypercapnic respiratory failure

Open Access Non-Invasive Ventilation Original Article

Despite declining rates of smoking in Europe and North America, Chronic Obstructive Lung Disease (COPD) remains a major cause of long-term morbidity and mortality with frequent hospitalizations adding to the cost of care [ 1 , 2 ]. Patients …

Implications of Cardiopulmonary Risk for the Management of COPD: A Narrative Review

Chronic obstructive pulmonary disease (COPD) constitutes a major global health burden and is the third leading cause of death worldwide. A high proportion of patients with COPD have cardiovascular disease, but there is also evidence that COPD is a …

Systematic Literature Review on the Incidence of Herpes Zoster in Populations at Increased Risk of Disease in the EU/EEA, Switzerland, and the UK

Open Access Shingles Original Research

Primary infection by the varicella-zoster virus leads to childhood varicella (chickenpox) in the majority of the population. The virus remains dormant in the dorsal root ganglia, and can be reactivated later in life, causing herpes zoster (HZ) [ 1 …