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Free for a limited time Ischemic Stroke Review

Collateral circulation: the future of ischemic stroke therapy?

Intracranial collateral circulation plays a pivotal role in shaping the prognosis and potential therapeutic interventions in patients with ischemic stroke.

Editor's Choice

Antipsychotic use in dementia has broad adverse outcomes

10-05-2024 Dementia News

Antipsychotic treatment of behavioral and psychological symptoms in patients with dementia is known to increase risk of stroke and death, but new findings indicate a broader range of adverse outcomes.

Anti-PF4 antibody-related disorder initially presenting as ICH

Open Access Cerebral Hemorrhage Case Study

Anti-platelet factor (PF4) disorders are severe and diagnosis may be challenging. Intracranial hemorrhage could present first but usually develops secondary to cerebral venous sinus thrombosis.

Preventing and treating stroke in type 2 diabetes

Open Access Type 2 Diabetes Review

The risks of ischemic and hemorrhagic stroke and poor neurological outcomes after stroke are increased in people with type 2 diabetes. Explore how to manage the hyperacute stroke stage and prevent CV disease.

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Webinar | 02-05-2024 | 17:30 (CEST)

Keynote webinar | Spotlight on sleep in brain health

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.

Dr. Rolf Fronczek
Dr. Renata Riha
Dr. Sven Rupprecht
Developed by: Springer Medicine

Case Studies

Anti-PF4 antibody-related disorder initially presenting as ICH

Open Access Cerebral Hemorrhage Case Study

Anti-platelet factor (PF4) disorders are severe and diagnosis may be challenging. Intracranial hemorrhage could present first but usually develops secondary to cerebral venous sinus thrombosis.

New ophthalmic signs of procedural stroke

Open Access Stroke Case Study

Procedural stroke is a major complication of cardiac catheterization and endovascular procedures, and recognizing the signs is crucial. In this case, internuclear ophthalmoplegia caused blurred vision, diplopia, and dizziness on lateral gaze.

Recurrent stroke in a young woman with patent foramen ovale

Open Access Congenital Heart Anomaly Case Study

A 31-year-old woman taking oral contraceptives presented with repetitive ischemic strokes before a patent foramen ovale was detected and closed. The dual risk of an undiagnosed PFO and common use of oral contraceptives should be considering in young women presenting with stroke symptoms. 

Current Reviews

Efficacy and safety of intravenous tenecteplase compared to alteplase before mechanical thrombectomy in acute ischemic stroke: a meta-analysis

Open Access Alteplase Review

Mechanical thrombectomy (MT) has emerged as the treatment of choice for acute ischemic stroke (AIS) with large vessel occlusion, with its effectiveness confirmed in multiple randomized trials [ 1 ]. Prior to MT, intravenous thrombolysis is widely …

Effects of spinal mobilization on physical function in patients with stroke: a systematic review and meta-analysis

Stroke Review Article

This systematic review and meta-analysis aimed to identify, critically appraise, and synthesize current evidence regarding the effects of spinal mobilization on physical function in patients with stroke. Three databases, PubMed, Embase, and …

Utilities for Complications Associated with Type 2 Diabetes: A Review of the Literature

Open Access Type 2 Diabetes Review

Health state utility values provide a quantitative indication of the extent to which a particular disease, complication or treatment-related side effect influences the quality of life (QoL) of an individual. Utility values quantify QoL on a scale …

Patent foramen ovale closure in ischemic stroke patients with and without thrombophilia: a systematic review and meta-analyses

Ischemic stroke patients with thrombophilia and patient foramen ovale (PFO) may have an increased risk of recurrent stroke and transient ischemic attack (TIA), and may benefit from PFO closure. However, screening for thrombophilia is not routinely …

Alzheimer's Disease Independent Medical Education

Neuroimaging for Alzheimer’s disease: eLearning (Link opens in a new window)

Neuroimaging plays an increasingly critical role in clinical practice. PET Pearls is an interactive activity designed to improve your confidence and accuracy when interpreting imaging for early signs of cognitive impairment.

Supported by: Lilly

Developed by: Springer Healthcare IME
Stroke Podcast

Episode 8: AI in stroke

About 50% of stroke patients have an unfavorable outcome. Predicting outcome is challenging but is key to understanding how best to treat patients.

Prof Susanne Wegener discusses her team’s work to develop deep learning models that outperform neurologists when predicting outcome based on imaging data alone or in combination with clinical data.

Prof. Dr. Susanne Wegener

Further Reading

Complications related to short peripheral intravenous catheters in patients with acute stroke: a prospective, observational, single-cohort study

Open Access Stroke IM - ORIGINAL

Patients with acute stroke often require venous access to facilitate diagnostic investigations or intravenous therapy. The primary aim of this study was to describe the rate and type of complications associated with the placement of a short …

Recurrent cerebrovascular events after recent small subcortical infarction

Open Access Cerebral Small Vessel Disease Original Research

Cerebral small vessel disease (SVD) is an important cause of ischaemic stroke as well as intracerebral haemorrhage, and is also associated with the development of vascular dementia, gait disturbance and depression [ 1 , 2 ].

Echocardiographic monitoring of myocardial function in a female patient with right heart Loeffler endocarditis at thrombotic stage after Epstein-Barr-virus infection

Open Access Endocarditis Case in point

Loeffler endocarditis is the result of eosinophilic infiltration of the myocardium [ 1 – 3 ]. The possible cause can be a hypereosinophilic reaction due to drugs or parasites [ 4 ]. Also isolated tissue infiltrations without peripheral …

Reperfusion therapies in patients with acute ischaemic stroke and atrial fibrillation: data on safety and effectiveness from a multi-centre cohort study

Open Access Atrial Fibrillation Original Article

Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia encountered in clinical practice, present in approximately 15% to 20% of all ischaemic strokes [ 1 ]. Moreover, AF has been reported to increase the risk of ischemic stroke …