PhALLCON trial results suggest a role for ponatinib plus reduced-intensity chemotherapy in the treatment of newly diagnosed Philadelphia chromosome-positive ALL.
Learn about when to test for cancer predisposition syndromes in patients with sarcoma, and the additional considerations for treatment and imaging in case of a positive result.
A French cohort study has found a significantly increased risk for leukemia in children born after fresh or frozen embryo transfer versus those conceived naturally.
An overview of the renal, hepatic, and cardiac adverse effects of cisplatin as well as the current strategies for managing these toxicities in clinical practice.
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How do nutrition, supplements and antibiotics impact patient outcomes?
Recent research suggests that the gut microbiome could be an important modulator of response to CAR T-cell therapy in patients with hematologic cancers.
Prof. Marion Subklewe takes us through the latest evidence, highlighting the impact of antibiotics, nutrition, and dietary supplements, and discusses how to devise interventions to improve patient outcomes.
A man receiving abiraterone for prostate cancer developed severe hypokalemia, which led to polymorphic ventricular tachycardia and cardiac arrest. It is important to consider iatrogenic causes in cases of arrhythmia.
Intermittently scanning CGM detected hypoglycemia in a woman previously diagnosed with schizophrenia and treated with antipsychotic medication. Insulinoma was diagnosed and resected, resolving her neuropsychiatric symptoms.
Live: Monday 10 June 2024, from 16:30 – 18:00 (CEST)
In this live interactive webinar, a multidisciplinary team of speakers will provide practical guidance on managing patients with cutaneous T-cell lymphoma. Learn about the key aspects of diagnosis and treatment via a series of patient cases.
After immune checkpoint inhibitor (ICI) comes into third-line treatment of advanced gastric cancer, the therapeutic strategy has been dramatically changed. Recent first-line regimen, which consists of ICI and chemotherapeutic agents, prolonged …
Pancreatic cancer has a dismal prognosis in the general population. However, early detection and treatment of disease in high-risk individuals can improve survival, as patients with localized disease and especially patients with lesions smaller …
Among individuals with pancreatic ductal adenocarcinoma (PDAC) 5–10% have a pathogenic germline variant (PGV) in a PDAC susceptibility gene. Guidelines recommend genetic testing among all individuals with PDAC. Additionally, at-risk relatives of …
As in Western countries, familial pancreatic cancer accounts for 5–7% of pancreatic cancer (PC) in Japan. Opportunities for diagnosing hereditary pancreatic cancer (HPC) are increasing owing to the coverage of companion diagnostics and cancer …
Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.
The ADAURA trial has, as of this year, demonstrated an overall survival benefit with the adjuvant use of osimertinib in people with resectable NSCLC.
We take an in-depth look at the study with Dr. Luis Paz-Ares, who outlines the study findings, discusses the clinical implications, and addresses the pertinent questions raised by the trial.
A collaborative program highlighting the importance of molecular assessments and targeted treatment selection in people with biomarker-positive disease. Submit your questions for the experts now.
A series of patient cases underpin this live interactive webinar that aims to provide practical guidance on a multidisciplinary approach to managing patients with cutaneous T-cell lymphoma.
Identifying molecular biomarkers is crucial in determining the best targeted treatment options for your patients with advanced thyroid cancer.
Join our expert-led multi-format educational program that explores the continuing discovery of new genomic targets and delivers the latest research in molecular testing and the application of targeted therapies for thyroid cancer.
The World Health Organization (WHO) classification groups soft tissue tumors into eleven categories, and further divides these categories into benign, intermediate, and malignant [ 1 , 2 ]. The most common category of soft tissue tumors is the …
Pharyngocutaneous fistula (PCF) is the commonest complication after total laryngectomy [ 1 ]. It develops as a result of leakage of saliva through the pharyngeal repair line [ 2 , 3 ]. PCF contributes to increased morbidity following laryngectomy …
Kristen Rat Sarcoma viral oncogene (KRAS) mutations are one of the most common oncogenic drivers found in 12–14% of non-small cell lung cancer (NSCLC) and 4% of colorectal cancer tumors. Although previously difficult to target, sotorasib and …
Imaging, cytologic, histologic, and molecular investigations all contributed to the diagnosis of a rare case of HTT in a woman with an incidentally discovered mass in the left lobe of her thyroid gland.
