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Internal Medicine Gastroenterology

Gastroenterology

ERCP in a low-weight infant with obstruction jaundice

Endoscopic retrograde cholangiopancreatography is used extensively in pediatric patients for diagnosing and treating biliary and pancreatic diseases, but is challenging in infants. Could this technique help?

Perforated appendicitis: room for improvement?

Free for a limited time Appendicitis Review

Appendicitis has been described for over 300 years, but care practices vary widely. Explore the risk factors for perforated appendicitis in children and recommendations for surgical and antimicrobial management.

Does intestinal permeability have a role in hypertension?

Open Access Hypertension Review

Evidence from animal models supports the presence of intestinal barrier dysfunction in hypertension, but what is the evidence in humans? Could hypertension increase gut permeability, or vice-versa?

Management of dysphagia in head and neck cancer

Open Access Head and Neck Cancer Review

Speech and language therapists play a key role in the assessment and management of dysphagia following head and neck cancer radiotherapy. What are the current therapeutic approaches and the areas of unmet need?

The gut microbiome in older adults

Open Access Geriatrics and Gerontology Review

The gut microbiome has a key role in host health, but what do we know about the gut microbiome in older adults? Can aging and its associated features be modulated by gut bacteria?

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Episode 9: The gut microbiome and CAR T-cell therapy

How do nutrition, supplements and antibiotics impact patient outcomes?

Recent research suggests that the gut microbiome could be an important modulator of response to CAR T-cell therapy in patients with hematologic cancers.

Prof. Marion Subklewe takes us through the latest evidence, highlighting the impact of antibiotics, nutrition, and dietary supplements, and discusses how to devise interventions to improve patient outcomes.

Prof. Marion Subklewe

Case Studies

ERCP in a low-weight infant with obstruction jaundice

Endoscopic retrograde cholangiopancreatography is used extensively in pediatric patients for diagnosing and treating biliary and pancreatic diseases, but is challenging in infants. Could this technique help?

Siblings with familial chylomicronemia syndrome

Open Access Hypertriglyceridemia Case Study

Familial chylomicronemia syndrome is a monogenic form of severe hypertriglyceridemia that increases the risk of pancreatitis. In this case, two brothers had familial chylomicronemia syndrome caused by rare GPIHBP1 deletions.

Insulinoma misidentified as schizophrenia

Free for a limited time Insulinoma Case Study

Intermittently scanning CGM detected hypoglycemia in a woman previously diagnosed with schizophrenia and treated with antipsychotic medication. Insulinoma was diagnosed and resected, resolving her neuropsychiatric symptoms.

Mastering chronic pancreatitis pain: A multidisciplinary approach and practical solutions

Severe pain is the most common symptom of chronic pancreatitis. In this live webinar, experts shared the latest insights in pain management for chronic pancreatitis patients. Experts from a range of disciplines discussed pertinent cases and provided practical suggestions for use within clinical practice.

CME-accredited on-demand version coming soon.

Sponsored by: Viatris

Developed by: Springer Healthcare

Current Reviews

Probiotics: an alternative anti-parasite therapy

Probiotics Review Article

This paper review about probiotic effects and mechanism of action against the gut and non-gut helminths and protozoan parasites. Gastrointestinal parasitic infections are considered a serious health problem and are widely distributed globally. The …

Obesity and Esophageal Dysfunction

Obesity is now the most common chronic disease in the world, with more than 1 billion people affected worldwide [ 1 ]. It is projected that by 2030, 1 in 2 persons will meet criteria for obesity and 1 in 4 persons for severe obesity in the United …

Physical activity in the prevention and management of inflammatory bowel disease: a systematic review

Open Access Chronic Inflammatory Bowel Disease Review Article

The term inflammatory bowel disease (IBD) indicates a group of chronic and lifelong diseases characterized by inflammation of the gastrointestinal tract, including Crohn’s disease (CD) and ulcerative colitis (UC) (Yeshi et al. 2020 ). CD can affect …

Treatment strategy for HER2-negative advanced gastric cancer: salvage-line strategy for advanced gastric cancer

Open Access Gastric Cancer Invited Review Article

After immune checkpoint inhibitor (ICI) comes into third-line treatment of advanced gastric cancer, the therapeutic strategy has been dramatically changed. Recent first-line regimen, which consists of ICI and chemotherapeutic agents, prolonged …

Webinar (Link opens in a new window)

Interact with experts from established amyloidosis centers who can offer you specialized guidance to support your mission to set up a local center. Network with other HCPs in your locality to discuss region-specific challenges in establishing amyloidosis centers. 

Supported by:
  • AstraZeneca and Alexion
Developed by: Springer Healthcare IME
SPONSORED

Webinar

2.0 NVMDL CME points

Severe pain is the most common symptom of chronic pancreatitis. In this live webinar, experts shared the latest insights in pain management for chronic pancreatitis patients. Experts from a range of disciplines discussed pertinent cases and provided practical suggestions for use within clinical practice.

Sponsored by:
  • Viatris
Developed by: Springer Healthcare

News | Articles | Videos (Link opens in a new window)

Expert insights, latest news and cutting-edge data reported from The Liver Meeting, Boston covering PBC treatment to arm HCPs with the latest information to optimize patients’ outcomes.

Supported by:
  • Ipsen
Developed by: Springer Healthcare IME

Further Reading

Clinical evaluation of a machine learning-based dysphagia risk prediction tool

Open Access Dysphagia Miscellaneous

Dysphagia is a very common but often underdiagnosed condition. Available data vary considerably, but epidemiologic surveys show that dysphagia was present in 2.4% of all hospital discharges and was more frequent in older patients and in men.

The failure of biological treatment in axial spondyloarthritis is linked to the factors related to increased intestinal permeability and dysbiosis: prospective observational cohort study

Open Access Spondyloarthropathy Observational Research

Currently, the therapeutic management for axial spondyloarthropathy follows the guidelines of Assessment of SpondyloArthritis International Society-European Alliance of Associations for Rheumatology (ASAS-EULAR), which recommends the inclusion of …

Divarasib in the Evolving Landscape of KRAS G12C Inhibitors for NSCLC

Open Access NSCLC Leading Article

Kristen Rat Sarcoma viral oncogene (KRAS) mutations are one of the most common oncogenic drivers found in 12–14% of non-small cell lung cancer (NSCLC) and 4% of colorectal cancer tumors. Although previously difficult to target, sotorasib and …

Efficacy and safety of robotic versus laparoscopic liver resection for hepatocellular carcinoma: a propensity score-matched retrospective cohort study

Open Access Hepatocellular Carcinoma Original Article

Primary liver cancer (PLC) is the sixth most common cancer worldwide and the third most common cause of cancer death, with hepatocellular carcinoma (HCC) accounting for about 85% of all PLC [ 1 ]. Despite the rapid advancements in medical …