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09-07-2022 | Vaccination | Research Letter

Kinetics of the humoral response 1-year following vaccination with BNT162b2 SARS-CoV-2 vaccine among maintenance hemodialysis patients

Authors: Ori Wand, Yael Einbinder, Naomi Nacasch, Tamar Halperin, Daniel Erez, Ayelet Grupper, Sydney Benchetrit, Michael Lishner, Amir Bar-Shai, Moshe Shashar, Keren Cohen-Hagai

Published in: Journal of Nephrology | Issue 1/2023

Excerpt

Widespread vaccination has led to a reduced incidence of COVID-19. However, the combined effect of declining effectiveness over time and the emergence of highly transmissible variants of concern, led to breakthrough infections among vaccinated individuals [1]. A third dose of the BNT162b2 (Pfizer-BioNTech) vaccine was effective in reducing SARS-CoV-2 infections and severe COVID-19 [1]. …

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Lipsitch M, Krammer F, Regev-Yochay G, Lustig Y, Balicer RD (2022) SARS-CoV-2 breakthrough infections in vaccinated individuals: measurement, causes and impact. Nat Rev Immunol 22(1):57–65. https://doi.org/10.1038/s41577-021-00662-4CrossRef

Espi M, Charmetant X, Barba T et al (2022) A prospective observational study for justification, safety, and efficacy of a third dose of mRNA vaccine in patients receiving maintenance hemodialysis. Kidney Int 101(2):390–402. https://doi.org/10.1016/j.kint.2021.10.040CrossRef

Wand O, Nacasch N, Fadeela A et al (2022) Humoral response and breakthrough infections with SARS-CoV-2 B.1.617.2 variant in vaccinated maintenance hemodialysis patients [published online ahead of print, 2022 Feb 17]. J Nephrol 2022:1–9. https://doi.org/10.1007/s40620-022-01245-9CrossRef

Shashar M, Nacasch N, Grupper A et al (2022) Humoral response to Pfizer BNT162b2 vaccine booster in maintenance hemodialysis patients. Am J Nephrol 53(2–3):207–214. https://doi.org/10.1159/0005216765CrossRef

Housset P, Kubab S, Pardon A et al (2022) Waning but persistent humoral response 6 months after the third dose of the mRNA BNT162b2 vaccine in hemodialysis and peritoneal dialysis patients. J Nephrol 35(3):783–785. https://doi.org/10.1007/s40620-022-01276-2CrossRef

Garcia-Beltran WF, St Denis KJ, Hoelzemer A et al (2022) mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant. Cell 185(3):457-466.e4. https://doi.org/10.1016/j.cell.2021.12.0337CrossRef

Anand S, Montez-Rath ME, Han J et al (2022) SARS-CoV-2 vaccine antibody response and breakthrough infection in patients receiving dialysis. Ann Intern Med 175(3):371–378. https://doi.org/10.7326/M21-4176CrossRef

Title: Kinetics of the humoral response 1-year following vaccination with BNT162b2 SARS-CoV-2 vaccine among maintenance hemodialysis patients
Authors: Ori Wand
Yael Einbinder
Naomi Nacasch
Tamar Halperin
Daniel Erez
Ayelet Grupper
Sydney Benchetrit
Michael Lishner
Amir Bar-Shai
Moshe Shashar
Keren Cohen-Hagai
Publication date: 09-07-2022
Publisher: Springer International Publishing
Keywords: Vaccination
SARS-CoV-2
COVID-19
Published in: Journal of Nephrology / Issue 1/2023
Print ISSN: 1121-8428
Electronic ISSN: 1724-6059
DOI: https://doi.org/10.1007/s40620-022-01377-y

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