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Open Access 01-12-2025 | Uveitis | Review

Inadequacies in uveitis: misnomers, incongruencies, persistence of obsolete terminologies & inappropriate guidelines, treatment inadequacies, and misinterpretations

Authors: Carl P. Herbort Jr, Ioannis Papasavvas, Masaru Takeuchi, Yoshihiko Usui, De-Kuang Hwang, Sagnik Sen

Published in: Journal of Ophthalmic Inflammation and Infection | Issue 1/2025

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Abstract

Background

Inadequacies in medicine are manifold including inadequate influence of opinion leaders and consensus groups on terminology, diagnostic criteria and treatment guidelines, obsolete classifications and terms as well as misinterpretations of disease mechanisms. This is no different for uveitis and possibly even more pronounced as these are rare entities.

Purpose

To underline inadequacies in uveitis including inadequate diagnostic criteria and treatment guidelines, misnomers, obsolescence of terminology, misinterpretation of disease processes and inadequate or underuse of investigative modalities in uveitis. This is a first report to be followed by others.

Methods

A critical retrospective literature review of selected inadequacies in uveitis practice.

Results

We investigate the mechanism of abuse of power of opinion leaders through the historical events such as the delay in acceptance of antiviral treatment for zoster ophthalmicus, report inadequacies and misnomers resulting from opinion articles or opinion surveys, inadequate treatment guidelines such as for Vogt-Koyanagi-Harada disease (VKH) , delays in adopting appropriate classifications, inappropriate pathophysiological interpretations such as for multiple evanescent white dot syndromes (MEWDS), reluctance to implement ICGA use, a crucial biomarker for choroiditis, among others.

Conclusion

Inadequacies in uveitis are not so rare and often result from inadequate influence of opinion leaders oe groups. Some are harmless although annoying, such as misnomers, while others can be harmful such as inadequate treatment guidelines.
Literature
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Metadata
Title
Inadequacies in uveitis: misnomers, incongruencies, persistence of obsolete terminologies & inappropriate guidelines, treatment inadequacies, and misinterpretations
Authors
Carl P. Herbort Jr
Ioannis Papasavvas
Masaru Takeuchi
Yoshihiko Usui
De-Kuang Hwang
Sagnik Sen
Publication date
01-12-2025
Publisher
Springer Berlin Heidelberg
Keyword
Uveitis
Published in
Journal of Ophthalmic Inflammation and Infection / Issue 1/2025
Electronic ISSN: 1869-5760
DOI
https://doi.org/10.1186/s12348-025-00470-0

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