Urology

Practical guidance for the diagnosis, management, and treatment of pediatric andrological disorders, including cryptorchidism, micropenis, hypospadias, and differences in sex development.

Discover the two conceptually distinct paradigms that could transform the neoadjuvant treatment of cisplatin-ineligible patients with muscle-invasive bladder cancer, and understand how they might be selected and sequenced.

This case of a testicular cancer patient with cystic fibrosis and liver cirrhosis shows that monitoring of etoposide concentrations can be beneficial in complex scenarios involving organ dysfunction and/or potential drug–drug interactions.

A case of immune-related gastritis complicated by subsequent cytomegalovirus gastritis in a patient undergoing combination therapy with ipilimumab and nivolumab for renal cell carcinoma.

Three trials point to the potential of fecal microbiota transplantation to enhance the efficacy of immune checkpoint inhibitor-based therapy in people with cancer.

Growing evidence suggests that polycystic ovary syndrome is not solely a reproductive endocrinologic disorder, but a multisystem syndrome with reproductive, endocrine, metabolic, and psychiatric manifestations.

Androgen receptor-targeted agents and docetaxel are increasingly being used earlier in the disease course in men with metastatic prostate cancer. So what are the options for castration-resistant prostate cancer?

Study shows a significant association between the presence of color vision deficiency and worse survival among people with bladder cancer, but not those with colorectal cancer.

Data from a large cohort has revealed a significant association between higher consumption of certain food preservatives and an increased incidence of cancer and type 2 diabetes.

Aztreonam-avibactam is a novel fixed-dose combination antibiotic for the treatment of serious bacterial infections caused by aerobic Gram-negative pathogens, including cIAI, HAP/VAP and cUTI. Examine the data on its efficacy, safety, and tolerability.

A comprehensive review on hypoparathyroidism, offering an updated and holistic perspective on its management to support the delivery of effective and individualized care across the spectrum of disease severity.

Are concerns about the effect of cosmetics on health warranted? Explore what’s known about the impact of endocrine-disrupting chemicals in cosmetics, such as benzophenones, triclosan, phthalates, and parabens.

In non-endemic regions, low clinical suspicion and limited access to specific laboratory tests may delay diagnosis of melioidosis. This series of imported cases illustrates its diverse clinical manifestations and the recommended approaches to treatment.

Real-world data suggest that upfront dose reduction of enfortumab vedotin in advanced urothelial cancer does not adversely affect overall survival.

Adjuvant atezolizumab significantly improved the survival of patients with muscle-invasive bladder cancer who tested positive for ctDNA by serial testing in the IMvigor011 trial.

Semen analysis remains the gold standard when evaluating male fertility potential, but could alternative diagnostic approaches and new technologies provide meaningful insights into what is happening within the testis?

The risk for external genital infections is increased in men with type 2 diabetes who take SGLT2 inhibitors compared with those who take GLP-1 receptor agonists.

Understand the evolving role of neoadjuvant and adjuvant therapies in the treatment of muscle-invasive bladder cancer, and the importance of biomarker-driven patient selection to refine treatment decisions.

Explore the evolution of prostate-specific antigen from its biochemical discovery to its present-day clinical applications in early cancer detection and disease monitoring, and find out what the future holds. 

A woman with abdominal pain was diagnosed with ureteral stones, but her pain persisted despite stent placement. A prior diagnosis of type 2 diabetes led to diabetic ketoacidosis being identified as the cause of the pain.