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Open Access 07-12-2024 | Urinary Incontinence

Health-related quality of life and sexual function among women with overweight or obesity and urinary incontinence: a cross-sectional study

Authors: Zhao Tian, Xiuqi Wang, Linru Fu, Zhe Du, Tangdi Lin, Wei Chen, Zhijing Sun

Abstract

Purpose

To assess the health related quality of life (HRQoL) and sexual function related to urinary incontinence (UI) severity among women with overweight or obesity.

Methods

From September 2023 to January 2024, a cross-sectional was conducted among women seeking weight loss with overweight or obesity focusing on the symptoms and effects of UI. The degree of UI severity, UI-specific HRQoL, sexual function, and generic HRQoL were detected via Incontinence Modular Questionnaire-Urinary Incontinence Short Form (ICIQ-UI-SF), Incontinence Impact Questionnaire-Short Form (IIQ-7), Short-form Prolapse Incontinence Sexual Questionnaire (PISQ-12), and European Quality of Life-5 Dimensions 5-Level questionnaire (EQ-5D-5 L) respectively.

Results

Out of 1205 valid responses, 564 (46.8%) reported UI with 354 classified as mild, 179 as moderate, and 31 as severe based on ICIQ-UI-SF scores. The mean age and body mass index of the respondents were 36.65 years and 29.9 kg/m², respectively. Individuals with more severe symptoms of UI exhibited correspondingly lower levels of UI-specific HRQoL, sexual function, and generic HRQoL. Although the correlations were weak, the severity of UI symptoms measured by ICIQ-UI-SF and IIQ-7 were significantly correlated with the mean utility values (r=-0.335, and − 0.351, P<0.001) of EQ-5D-5 L especially in the domains of anxiety/depression symptoms (r = 0.339 and 0.322, P<0.001).

Conclusion

Nearly half of women seeking weight loss with overweight or obesity may experience UI, which significantly affects HRQoL and sexual function. The severity of UI symptoms is significantly correlated with the generic HRQoL measured by EQ-5D-5 L, especially in the domain of anxiety/depression symptoms.

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Mohammed, M. S., Sendra, S., Lloret, J., & Bosch, I. (2018). Systems and WBANs for Controlling obesity. Journal of Healthcare Engineering, 2018, 1564748. https://doi.org/10.1155/2018/1564748CrossRefPubMedPubMedCentral

Zhang, X., Ha, S., Lau, H. C., & Yu, J. (2023). Excess body weight: Novel insights into its roles in obesity comorbidities. Seminars in cancer Biology, 92, 16–27. https://doi.org/10.1016/j.semcancer.2023.03.008CrossRefPubMed

Friedman, T., & Dietz, H. P. (2022). Does obesity change the perception of pelvic organ prolapse? Archives of Gynecology and Obstetrics, 305(6), 1491–1495. https://doi.org/10.1007/s00404-022-06430-6CrossRefPubMed

Chilaka, C., Toozs-Hobson, P., & Chilaka, V. (2023). Pelvic floor dysfunction and obesity, Best practice & research. Clinical Obstetrics & Gynaecology, 90, 102389. https://doi.org/10.1016/j.bpobgyn.2023.102389CrossRef

Doumouchtsis, S. K., Loganathan, J., & Pergialiotis, V. (2022). The role of obesity on urinary incontinence and anal incontinence in women: A review. BJOG: An International Journal of Obstetrics and Gynaecology, 129(1), 162–170. https://doi.org/10.1111/1471-0528.16848CrossRefPubMed

Shang, X., Fu, Y., Jin, X., Wang, C., Wang, P., Guo, P., Wang, Y., & Yan, S. (2023). Association of overweight, obesity and risk of urinary incontinence in middle-aged and older women: A meta epidemiology study. Frontiers in Endocrinology, 14, 1220551. https://doi.org/10.3389/fendo.2023.1220551CrossRefPubMedPubMedCentral

Saadedine, M., Faubion, S. S., Grach, S. L., Nordhues, H. C., & Kapoor, E. (2024). Association between obesity and female sexual dysfunction: A review. Sexual Medicine Reviews, 12(2), 154–163. https://doi.org/10.1093/sxmrev/qead047CrossRefPubMed

McNabney, S. M., Gletsu-Miller, N., & Rowland, D. L. (2023). Sexual function and satisfaction in the context of obesity. Current Diabetes Reports, 23(11), 315–327. https://doi.org/10.1007/s11892-023-01523-1CrossRefPubMed

Frigerio, M., Barba, M., Cola, A., Braga, A., Celardo, A., Munno, G. M., Schettino, M. T., Vagnetti, P., De Simone, F., Di Lucia, A., Grassini, G., & Torella, M. (2022). Quality of life, psychological wellbeing, and sexuality in women with urinary incontinence-where are we now: A narrative review, Medicina (Kaunas. Lithuania), 58(4). https://doi.org/10.3390/medicina58040525

10.

Choi, J. M., Jiang, J., Chang, J., Ziogas, A., Jiang, L., & Anton-Culver, H. (2022). Impact of lifetime obesity on urinary incontinence in the women’s Health Initiative. The Journal of Urology, 207(5), 1096–1104. https://doi.org/10.1097/ju.0000000000002380CrossRefPubMed

11.

Husk, K. E., Leong, K., Rogers, R. G., & Deverdis, E. C. (2023). Public Awareness of Obesity and risk of Pelvic Floor disorders: A Cohort Study, Urogynecology (Philadelphia. Pa), 29(2), 260–265. https://doi.org/10.1097/spv.0000000000001257CrossRef

12.

Davis, S., & Wailoo, A. (2013). A review of the psychometric performance of the EQ-5D in people with urinary incontinence. Health and Quality of life Outcomes, 11, 20. https://doi.org/10.1186/1477-7525-11-20CrossRefPubMedPubMedCentral

13.

Ramírez, J. A., Tirado, P. O., Samur, C. S., Gamboa, C. V., & Oliveres, X. C. (2023). Health-related quality of life in women aged 20–64 years with urinary incontinence. International Urogynecology Journal, 34(7), 1405–1414. https://doi.org/10.1007/s00192-022-05365-5CrossRefPubMed

14.

Alberti, K. G., Zimmet, P., & Shaw, J. (2006). Metabolic syndrome–a new world-wide definition. A Consensus Statement from the International Diabetes Federation, Diabetic medicine: a journal of the British Diabetic Association 23(5) 469 – 80. https://doi.org/10.1111/j.1464-5491.2006.01858.x

15.

Haylen, B. T., de Ridder, D., Freeman, R. M., Swift, S. E., Berghmans, B., Lee, J., Monga, A., Petri, E., Rizk, D. E., Sand, P. K., & Schaer, G. N. (2010). An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction. Neurourology and Urodynamics, 29(1), 4–20. https://doi.org/10.1002/nau.20798CrossRefPubMed

16.

Huang, L., Zhang, S. W., Wu, S. L., Ma, L., & Deng, X. H. (2008). The Chinese version of ICIQ: A useful tool in clinical practice and research on urinary incontinence. Neurourology and Urodynamics, 27(6), 522–524. https://doi.org/10.1002/nau.20546CrossRefPubMed

17.

Zhu, L., Yu, S. J., Lang, J. H., Xu, T., Lu, Y. X., Yang, X., & Li, B. (2011). [Validation of incontinence impact questionnaire short form in Chinese population]. Zhonghua Fu Chan Ke Za Zhi, 46(7), 505–509.PubMed

18.

Choi, E. P., Lam, C. L., & Chin, W. Y. (2014). The incontinence impact questionnaire-7 (IIQ-7) can be applicable to Chinese males and females with lower urinary tract symptoms. The Patient, 7(4), 403–411. https://doi.org/10.1007/s40271-014-0062-3CrossRefPubMed

19.

Luo, N., Liu, G., Li, M., Guan, H., Jin, X., & Rand-Hendriksen, K. (2017). Estimating an EQ-5D-5L value set for China, Value in health: The. Journal of the International Society for Pharmacoeconomics and Outcomes Research, 20(4), 662–669. https://doi.org/10.1016/j.jval.2016.11.016CrossRef

20.

Zhu, L., Yu, S., Xu, T., Yang, X., Lu, Y., & Lang, J. (2012). Validation of the Chinese version of the pelvic organ Prolapse/Urinary incontinence sexual questionnaire short form (PISQ-12), International journal of gynaecology and obstetrics: The official organ of the International Federation of. Gynaecology and Obstetrics, 116(2), 117–119. https://doi.org/10.1016/j.ijgo.2011.08.021CrossRef

21.

Ma, Y., Xu, T., Zhang, Y., Kang, J., Ma, C., & Zhu, L. (2020). Validation of the Chinese version of the pelvic organ prolapse symptom score (POP-SS). Menopause (New York N Y), 27(9), 1053–1059. https://doi.org/10.1097/gme.0000000000001580CrossRefPubMed

22.

Zhu, L., Lang, J., Liu, C., Han, S., Huang, J., & Li, X. (2009). The epidemiological study of women with urinary incontinence and risk factors for stress urinary incontinence in China. Menopause (New York N Y), 16(4), 831–836. https://doi.org/10.1097/gme.0b013e3181967b5dCrossRefPubMed

23.

Choi, E. P. H., Wan, E. Y. F., Chin, W. Y., & Lam, C. L. K. (2020). Lower urinary tract symptoms and health-related quality of life in Hong Kong primary care: A cross-sectional study. Quality of life Research: An International Journal of Quality of life Aspects of Treatment care and Rehabilitation, 29(5), 1311–1321. https://doi.org/10.1007/s11136-019-02402-7CrossRefPubMed

24.

Guo, W., Xie, S., Wang, D., & Wu, J. (2024). Mapping IWQOL-Lite onto EQ-5D-5L and SF-6Dv2 among overweight and obese population in China, Quality of life research. An International Journal of Quality of life Aspects of Treatment care and Rehabilitation, 33(3), 817–829. https://doi.org/10.1007/s11136-023-03568-xCrossRef

25.

Verbeek, M., Hayward, L., & Pelvic Floor Dysfunction And Its Effect On Quality Of Sexual Life. (2019). Sexual Medicine Reviews 7(4) 559–564. doi: https://doi.org/10.1016/j.sxmr.2019.05.007.CrossRefPubMed

26.

National Guideline, A., Reviews, N. I. C. E. E., & Collection (2021). Weight loss interventions: Pelvic floor dysfunction: prevention and non-surgical management: Evidence review J, National Institute for Health and Care Excellence (NICE) Copyright © NICE 2021., London.

27.

Sazonova, N. A., Kiseleva, M. G., Gadzhieva, Z. K., & Gvozdev, M. Y. (1999). [Urinary incontinence in women and its impact on quality of life], Urologiia (Moscow, Russia: (2) (2022) 136–139.

28.

Iqbal, I., Mustafa, G., & Ma, J. (2020). Deep learning-based morphological classification of human sperm heads. Diagnostics (Basel Switzerland), 10(5). https://doi.org/10.3390/diagnostics10050325

29.

Yáñez-Castillo, Y. M., Nogueras-Ocaña, M., Jiménez-Pacheco, A., Folgueral-Corral, M. E., & Arrabal-Martín, M. (2024). Preliminary results of the external urinary sphincter Uroflex^® on the quality of life of patients with male urinary incontinence after prostate surgery: Tolerance, severity of incontinence, and quality of life. International Urology and Nephrology. https://doi.org/10.1007/s11255-024-04027-3CrossRefPubMed

Title: Health-related quality of life and sexual function among women with overweight or obesity and urinary incontinence: a cross-sectional study
Authors: Zhao Tian
Xiuqi Wang
Linru Fu
Zhe Du
Tangdi Lin
Wei Chen
Zhijing Sun
Publication date: 07-12-2024
Publisher: Springer International Publishing
Keywords: Urinary Incontinence
Urinary Incontinence
Obesity
Obesity
Overweight
Anxiety
Published in: Quality of Life Research
Print ISSN: 0962-9343
Electronic ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-024-03868-w

Keynote webinar | Spotlight on advances in lupus

Springer Medicine

Health-related quality of life and sexual function among women with overweight or obesity and urinary incontinence: a cross-sectional study

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on advances in lupus

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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