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Journal of Anesthesia, Analgesia and Critical Care

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Open Access 01-12-2024 | Review

Understanding neuropathic pain: the role of neurophysiological tests in unveiling underlying mechanisms

Authors: Caterina Maria Leone, Andrea Truini

Published in: Journal of Anesthesia, Analgesia and Critical Care | Issue 1/2024

Abstract

Neuropathic pain, arising from lesions of the somatosensory nervous system, presents with diverse symptoms including ongoing pain, paroxysmal pain, and provoked pain, usually accompanied by sensory deficits. Understanding the pathophysiological mechanisms behind these symptoms is crucial for targeted treatment strategies. Neurophysiological techniques such as nerve conduction studies, reflexes, and evoked potentials help elucidate these mechanisms by assessing large myelinated non-nociceptive fibres and small nociceptive fibres. This argumentative review highlights the importance of tailored neurophysiological assessments for improving our understanding of the pathophysiological mechanisms behind neuropathic pain symptoms.

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Title: Understanding neuropathic pain: the role of neurophysiological tests in unveiling underlying mechanisms
Authors: Caterina Maria Leone
Andrea Truini
Publication date: 01-12-2024
Publisher: BioMed Central
Published in: Journal of Anesthesia, Analgesia and Critical Care / Issue 1/2024
Electronic ISSN: 2731-3786
DOI: https://doi.org/10.1186/s44158-024-00212-z

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