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BMC Pediatrics
Published in: BMC Pediatrics 1/2023

Open Access 02-09-2023 | Tumor Lysis Syndrome | Case report

Tumor lysis syndrome in premature infant prompting early resection of a large sacrococcygeal teratoma: a case report

Authors: Aditi Dey, Rita Wyrebek, Loraine Torres, Danilo Escoto, Fauzia Shakeel, Jennifer Mayer

Published in: BMC Pediatrics | Issue 1/2023

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Abstract

Background

Sacrococcygeal teratomas (SCTs) are the most common congenital neoplasm and often require resection soon after birth. There are rare reports of cardiac arrest during surgery due to manipulation of the tumor triggering secondary necrosis and hyperkalemia.

Case presentation

This case describes a very preterm infant with a SCT who develops spontaneous preoperative tumor lysis syndrome (TLS). The medical team utilized rasburicase and the patient underwent total gross resection at 40 h of life.

Conclusions

We emphasize the importance of the early recognition and management of tumor lysis syndrome in SCT with rasburicase, aggressive management of hyperkalemia and consideration of early resection of SCTs even in the case of a very premature infant.
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Metadata
Title
Tumor lysis syndrome in premature infant prompting early resection of a large sacrococcygeal teratoma: a case report
Authors
Aditi Dey
Rita Wyrebek
Loraine Torres
Danilo Escoto
Fauzia Shakeel
Jennifer Mayer
Publication date
02-09-2023

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