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Open Access 01-12-2025 | Tuberculosis | Case report

Cutaneous tuberculosis and its pleomorphic presentations in human immunodeficiency virus-negative patients: a case report

Authors: Rose Ekambi Kotto, Grace Anita Nkoro, Coralie Reine Mendouga Menye, Odette Berline Sigha, Ulrich Nguena Feungue, Christelle Ebongo Aboutou, Aristide Nguenmegne, Thierry Zo’obo, Edgar Mandeng Ma Linwa, Alain-Patrice Mélédié, Emmanuel Armand Kouotou

Published in: Journal of Medical Case Reports | Issue 1/2025

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Abstract

Background

Cutaneous tuberculosis is reported to be rare, especially in human immunodeficiency virus-negative patients but probably also underdiagnosed. This is because it presents with pictorial and anatomoclinical polymorphism. In Africa, despite tuberculosis being endemic, isolating the germ and/or obtaining histopathological confirmation constitutes a significant challenge. Literature on the clinical presentations and outcomes of patients with cutaneous tuberculosis is sparse in Cameroon and sub-Saharan Africa. This prompted us to report on the cases of cutaneous tuberculosis we encountered.

Case presentation

We report ten cases of cutaneous tuberculosis diagnosed in human immunodeficiency virus-negative patients from 2018 to 2022 in Cameroon. All cases included were confirmed by histology and/or laboratory test. The average age of our patients was 35.7 ± 20.3 years, with age ranges between 8 and 72 years. The sex ratio (M/F) was 1.5. The clinical forms identified were scrofuloderma (three cases), papulonecrotic tuberculid (two cases), and tuberculosis verrucosa cutis (two cases). Tubercular gumma, lupus vulgaris, and disseminated tuberculosis accounted for one case each. Under antituberculosis drugs, the clinical progress was favorable for all cases.

Conclusion

Cutaneous tuberculosis can present in various forms. Though rare in our setting, physicians should consider this diagnosis when faced with any chronic skin lesion that does not respond to conventional treatment.
Literature
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Metadata
Title
Cutaneous tuberculosis and its pleomorphic presentations in human immunodeficiency virus-negative patients: a case report
Authors
Rose Ekambi Kotto
Grace Anita Nkoro
Coralie Reine Mendouga Menye
Odette Berline Sigha
Ulrich Nguena Feungue
Christelle Ebongo Aboutou
Aristide Nguenmegne
Thierry Zo’obo
Edgar Mandeng Ma Linwa
Alain-Patrice Mélédié
Emmanuel Armand Kouotou
Publication date
01-12-2025
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2025
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-024-04918-0