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22-09-2023 | Transthoracic Echocardiography | Review Article

Cardiac myxomas: causes, presentations, diagnosis, and management

Authors: Elio Assaad Saad, Tishya Mukherjee, Georges Gandour, Nora Fatayerji, Aya Rammal, Peter Samuel, Nicolas Abdallah, Tejaswini Ashok

Published in: Irish Journal of Medical Science (1971 -)

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Abstract

Cardiac myxomas (CM) are one of the most common benign tumors which are typical in adults with a yearly incidence of 0.5–1 case per million individuals. This review article includes discussions based on existing literature on the role of interleukin interactions in the pathophysiology of cardiac myxoma which can lead to embolic complications, aneurysms, and CNS involvement. The objective of this narrative review was to study the variable clinical presentations of cardiac myxoma, its detection and diagnosis involving multiple modalities like genetic and hematological testing, echocardiography, CT, and MRI, of which transoesophageal echocardiogram shows excellent precision with a 90% to 96% accuracy in diagnosing CM. Individuals with the Carney complex are prone to such neoplasia. Cardiac myxomas are challenging to diagnose due to the ambiguity of their differential with thrombi. Myxomas can also be diagnosed by tumor markers like interleukin-6 and endothelial growth factors. The management of CM includes surgical excision like median sternotomy and robotic minimally invasive surgery. The use of robotic surgery in CM increased from 1.8% in 2012 to 15.1% in 2018. Tumor recurrences are uncommon but can occur due to inadequate surgical resection.
Literature
60.
go back to reference Kaltsas G, Kanakis G, Chrousos G (2018) Carney complex. In: Feingold KR, Anawalt B, Boyce A et al (eds) Endotext. MDText.com, Inc., South Dartmouth (MA), 2018 June 18 Kaltsas G, Kanakis G, Chrousos G (2018) Carney complex. In: Feingold KR, Anawalt B, Boyce A et al (eds) Endotext. MDText.com, Inc., South Dartmouth (MA), 2018 June 18
76.
go back to reference Matache R, Dumitrescu M, Bobocea A, Cordoș I (2016) Median sternotomy - gold standard incision for cardiac surgeons. J Clin Invest Surg 1(1) Matache R, Dumitrescu M, Bobocea A, Cordoș I (2016) Median sternotomy - gold standard incision for cardiac surgeons. J Clin Invest Surg 1(1)
77.
go back to reference Hanson EC, Gill CC, Razavi M, Loop FD (1985) The surgical treatment of atrial myxomas. Clinical experience and late results in 33 patients. J Thorac Cardiovasc Surg 89(2):298–303 Hanson EC, Gill CC, Razavi M, Loop FD (1985) The surgical treatment of atrial myxomas. Clinical experience and late results in 33 patients. J Thorac Cardiovasc Surg 89(2):298–303
79.
go back to reference Khan MS, Sanki PK, Hossain MZ et al (2013) Cardiac myxoma: a surgical experience of 38 patients over 9 years, at SSKM hospital Kolkata, India. South Asian J Cancer 2:83–86 CrossRefPubMedPubMedCentral Khan MS, Sanki PK, Hossain MZ et al (2013) Cardiac myxoma: a surgical experience of 38 patients over 9 years, at SSKM hospital Kolkata, India. South Asian J Cancer 2:83–86 CrossRefPubMedPubMedCentral
83.
go back to reference Vroomen M, Houthuizen P, Khamooshian A et al (2015) Long-term follow-up of 82 patients after surgical excision of atrial myxomas. Interact CardioVasc Thorac Surg 21:183–188 CrossRefPubMed Vroomen M, Houthuizen P, Khamooshian A et al (2015) Long-term follow-up of 82 patients after surgical excision of atrial myxomas. Interact CardioVasc Thorac Surg 21:183–188 CrossRefPubMed
84.
go back to reference Gummert JF, Barten MJ, Hans C et al (2002) Mediastinitis and cardiac surgery: an updated risk factor analysis in 10,373 consecutive adult patients. Thorac Cardiovasc Surg 50:87–91 CrossRefPubMed Gummert JF, Barten MJ, Hans C et al (2002) Mediastinitis and cardiac surgery: an updated risk factor analysis in 10,373 consecutive adult patients. Thorac Cardiovasc Surg 50:87–91 CrossRefPubMed
Metadata
Title
Cardiac myxomas: causes, presentations, diagnosis, and management
Authors
Elio Assaad Saad
Tishya Mukherjee
Georges Gandour
Nora Fatayerji
Aya Rammal
Peter Samuel
Nicolas Abdallah
Tejaswini Ashok
Publication date
22-09-2023
Publisher
Springer International Publishing
Published in
Irish Journal of Medical Science (1971 -)
Print ISSN: 0021-1265
Electronic ISSN: 1863-4362
DOI
https://doi.org/10.1007/s11845-023-03531-2