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Endocrinology Thyroid Disease

Thyroid Disease

Tumor microenvironment and management of medullary thyroid cancer

The absence or presence of primary tumor desmoplasia may be an alternative to conventional classification systems to help guide intraoperative management of sporadic medullary thyroid cancer.

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Editor's Choice

Exceptionally rare manifestation of papillary thyroid cancer

Spontaneous hepatic hemorrhage is a rare condition that is mostly seen in patients with hepatocellular carcinoma or hepatic adenomas. But in this case it was caused by metastasized papillary thyroid cancer.

Ablation of thyroid cancer: a double-edged sword?

Thyroid ablation technology has developed rapidly in the past 20 years, but these two cases highlight how incomplete ablation of thyroid nodules hinders its use as a treatment for thyroid cancer.

Thyroid tuberculosis mimicking multinodular goiter

A woman presented with anterior neck swelling of 6 years’ duration that had recently increased in size. The absence of other significant clinical and laboratory findings delayed the diagnosis of thyroid tuberculosis.

Novel therapies for anaplastic thyroid cancer

Genetic instability is a hallmark of anaplastic thyroid cancer. Find out more about the genomic and immune therapy options for recurrent or metastatic disease.

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Case Studies

Exceptionally rare manifestation of papillary thyroid cancer

Spontaneous hepatic hemorrhage is a rare condition that is mostly seen in patients with hepatocellular carcinoma or hepatic adenomas. But in this case it was caused by metastasized papillary thyroid cancer.

Ablation of thyroid cancer: a double-edged sword?

Thyroid ablation technology has developed rapidly in the past 20 years, but these two cases highlight how incomplete ablation of thyroid nodules hinders its use as a treatment for thyroid cancer.

Thyroid tuberculosis mimicking multinodular goiter

A woman presented with anterior neck swelling of 6 years’ duration that had recently increased in size. The absence of other significant clinical and laboratory findings delayed the diagnosis of thyroid tuberculosis.

Current Reviews

Diagnostic performance of 2-[18F]FDG PET/CT in recurrent differentiated thyroid cancer and elevated antithyroglobulin antibodies: an updated systematic review and bivariate meta-analysis

Differentiated thyroid carcinoma (DTC) is the most frequent endocrine cancer worldwide and is usually characterized by an excellent prognosis. Surgery (total or near-total thyroidectomy) and then radioiodine ( 131 I) remnant ablation are the …

Diagnosing and management of thyroid nodules and goiter – current perspectives

Due to the frequent diagnosis of benign thyroid nodules, it is necessary to deviate from the traditional paradigm based on frequent surgical treatment. This article highlights the evolution of diagnosis and treatment in recent years, beginning …

Therapeutic efficacy and patient compliance of levothyroxine liquid and softgel formulations taken with meals: a systematic review

Hypothyroidism is a common endocrine disorder caused by a lack of thyroid hormone that requires lifelong replacement therapy for the majority of patients. Studies in Northern Europe, Japan and the USA have found its prevalence to range between 0.6 …

Total Thyroidectomy Versus Partial Thyroidectomy for Non-Toxic Multinodular Goiter: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Thyroid follicular nodular disease (non-toxic multinodular goiter), the commonest thyroid disorder, can be managed with different surgical methods, including total thyroidectomy (TT), near-total thyroidectomy (NTT), subtotal thyroidectomy (STT) …

CME & eLearning

Webcast | Videos | Cases (Link opens in a new window)

Identifying molecular biomarkers is crucial in determining the best targeted treatment options for your patients with advanced thyroid cancer.

Join our expert-led multi-format educational program that explores the continuing discovery of new genomic targets and delivers the latest research in molecular testing and the application of targeted therapies for thyroid cancer.

Start by watching our webcast and short vodcasts.

Supported by:
  • Lilly
Developed by: Springer Healthcare IME

Further Reading

Psammoma bodies in thyroid: are they always indicative of malignancy? A multi-institutional study

Traditionally, psammoma bodies (PB) have been considered as tale-tell evidence of papillary thyroid carcinoma (PTC) and are frequently encountered in classic and other subtypes of PTCs. However, the presence of PBs in the thyroid gland does not …

SEOM-GETNE-TTCC Clinical guideline thyroid cancer (2023)

Thyroid cancer (TC) represents 3% of global cancer incidence. Recent changes have optimized treatment decisions based on risk assessment, molecular profiling, and imaging assessment, leading the development of targeted agents that have modified …

Consider or not consider: the unsolved question on the use of radioactive iodine for differentiated thyroid cancer with low to intermediate risk of recurrence

Differentiated thyroid cancer (DTC) refers to thyroid tumors derived from follicular cells, including papillary thyroid carcinoma (PTC), follicular thyroid carcinoma (FTC), oncocytic carcinoma (OCA), differentiated high-grade thyroid carcinoma …

MRI features of histological subtypes of thyroid cancer in comparison with CT findings: differentiation between anaplastic, poorly differentiated, and papillary thyroid carcinoma

Thyroid cancer is the ninth most common type of cancer worldwide. Approximately 75% of patients with thyroid cancer are females, and the median age of diagnosis is in the early 50 s. Furthermore, this disease is the most common malignancy in the …