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09-05-2024 | Thyroid Cancer | Original Article

Differentiated Thyroid Cancers with Synchronous Second Primary Cancers: Case Series

Authors: Devarajan Jebin Aaron, Priyank Rathod, Shailee Mehta, Ajinkya Pawar, Imran Nasir, Anish Chowdhury, Kanika Kapur, Mohit Sharma, Ketul Puj, Vikas Warikoo, Shailesh Patel, Keval Patel, Abhijeet Salunke, Priti Trivedi, Vivek Bande, Salahudheen Thottiyen, Sonal Trivedi, Nikunj Patel, Gautami Joshi, Shashank Pandya

Published in: Indian Journal of Otolaryngology and Head & Neck Surgery

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Abstract

The incidence of synchronous second primary cancer (SSPC) with DIfferentiated Thyroid Cancers (DTC) is a very rare entity. Very few case reports and case series were published in the literature. To enumerate the clinicopathological data of patients with DTC with SSPC. This is a single-center retrospective study. All the patients diagnosed with DTC and SSPC from January 2016 to July 2023 were included in the study. The demographic, clinicopathological data, and survival data were collected from the institute's database. Twelve patients were found to have DTC with SSPC. All the patients had papillary thyroid cancer. Ten patients had head and neck squamous cell carcinoma, one patient had malignant phyllodes tumor, and another patient had endometrioid adenocarcinoma as the SSPC. Six patients were diagnosed during preoperative evaluation, one patient was diagnosed 3 months after the oral malignancy diagnosis, and five patients were diagnosed with PTC in cervical nodes after neck dissection. Complete thyroid removal was done in six patients and hemithyroidectomy in two patients. The median follow-up was 25.55 months. The median overall survival was 40.97 months. Head and neck SCC is the most common SSPC with DTC. Since these are rare scenarios multi-disciplinary panel discussion can help in deciding management.
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Metadata
Title
Differentiated Thyroid Cancers with Synchronous Second Primary Cancers: Case Series
Authors
Devarajan Jebin Aaron
Priyank Rathod
Shailee Mehta
Ajinkya Pawar
Imran Nasir
Anish Chowdhury
Kanika Kapur
Mohit Sharma
Ketul Puj
Vikas Warikoo
Shailesh Patel
Keval Patel
Abhijeet Salunke
Priti Trivedi
Vivek Bande
Salahudheen Thottiyen
Sonal Trivedi
Nikunj Patel
Gautami Joshi
Shashank Pandya
Publication date
09-05-2024
Publisher
Springer India
Published in
Indian Journal of Otolaryngology and Head & Neck Surgery
Print ISSN: 2231-3796
Electronic ISSN: 0973-7707
DOI
https://doi.org/10.1007/s12070-024-04636-5