Skip to main content
ADVANCED SEARCH
Log in
Top
Current Neurology and Neuroscience Reports
Published in:

01-12-2025 | Thrombectomy | Review

Thrombectomy Selection in the Large Core Era: Implications for Regional Transfers

Authors: Luigi Cirillo, Mohamad Abdalkader, Piers Klein, Vivek S. Yedavalli, James E. Siegler, Matthew Kang, Liqi Shu, Fawaz Al Mufti, Shadi Yaghi, Anna Ranta, Thanh N. Nguyen

Published in: Current Neurology and Neuroscience Reports | Issue 1/2025

Login to get access

Abstract

Purpose of Review

This review aims to evaluate recent advances in large core stroke management with a focus on diagnostic imaging protocols to select patients for endovascular therapy.

Recent Findings

Recent randomized controlled trials have shown that thrombectomy can lead to favorable outcomes in patients with large infarcts, contradicting previous assumptions that thrombectomy was not indicated in such patients due to higher risks and very low benefits.

Summary

Although mechanical thrombectomy remains the gold standard of medical treatment for large vessel occlusions with demonstrated salvageable brain tissue, analysis of the results of recent randomized trials in patients with large ischemic stroke should help us expand patient selection, optimize timing, and explore different management modalities to improve the outcomes of therapy in these patients.
Literature
This content is only visible if you are logged in and have the appropriate permissions.
Metadata
Title
Thrombectomy Selection in the Large Core Era: Implications for Regional Transfers
Authors
Luigi Cirillo
Mohamad Abdalkader
Piers Klein
Vivek S. Yedavalli
James E. Siegler
Matthew Kang
Liqi Shu
Fawaz Al Mufti
Shadi Yaghi
Anna Ranta
Thanh N. Nguyen
Publication date
01-12-2025
Publisher
Springer US
Keyword
Thrombectomy
Published in
Current Neurology and Neuroscience Reports / Issue 1/2025
Print ISSN: 1528-4042
Electronic ISSN: 1534-6293
DOI
https://doi.org/10.1007/s11910-025-01421-x

Other articles of this Issue 1/2025

The Bidirectional Relationship Between Epilepsy and Alzheimer’s Disease

Emerging therapies for brain metastases

Advances in genetics of spinocerebellar ataxias

Fundus photography could transform emergency diagnostics

Pitfalls in diagnosing Wilson disease

Central Nervous System Manifestations of Cutaneous Lymphomas

EAN 2025

Unlock your free and exclusive access to the latest news and expert interviews from the European Academy of Neurology's annual congress.

Read more

How can your team use biomarkers to improve management of AD? (Link opens in a new window)

Our experts explore using biomarker tests and interpreting results, establishing a shared decision-making approach with patients and caregivers, and applying biomarker testing to guide treatment strategies.

This content is intended for healthcare professionals outside of the UK.

Supported by:
  • Lilly
Developed by: Springer Health+ IME
Register your interest
Image Credits