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The Journal of Headache and Pain

Issue 1/2025

Content (156 Articles)

Reduction of pain and functional disability over time in patients treated with zavegepant: a post-hoc analysis of the BHV3500-301 phase 3 randomized controlled trial

Lauren Powell, Fiona O’Sullivan, Pramoda Jayasinghe, Basia Rogula, Feng Dai, Jessica Cirillo, Samantha Sweeney, Lucy Abraham, Jessica Ailani

Influence of next-generation artificial intelligence on headache research, diagnosis and treatment: the junior editorial board members’ vision – part 2

Igor Petrušić, Chia-Chun Chiang, David Garcia-Azorin, Woo-Seok Ha, Raffaele Ornello, Lanfranco Pellesi, Eloisa Rubio-Beltrán, Ruth Ruscheweyh, Marta Waliszewska-Prosół, William Wells-Gatnik

Migraine in men

Mira P. Fitzek, Deirdre M. Boucherie, Tessa de Vries, Cleo Handtmann, Haniyeh Fathi, Bianca Raffaelli, Antoinette MaassenVanDenBrink

Effectiveness and tolerability of rimegepant in the acute treatment of migraine: a real-world, prospective, multicentric study (GAINER study)

Luigi Francesco Iannone, Gloria Vaghi, Gabriele Sebastianelli, Francesco Casillo, Antonio Russo, Marcello Silvestro, Francesca Pistoia, Giorgio Dalla Volta, Matteo Cortinovis, Alberto Chiarugi, Danilo Antonio Montisano, Maria Pia Prudenzano, Sabina Cevoli, Edoardo Mampreso, Gianluca Avino, Marina Romozzi, Mariarosaria Valente, Carla Fasano, Stefania Battistini, Antonio Granato, Elisa Maria Piella, Innocenzo Rainero, Raffaele Ornello, Roberto De Icco, Davide Mascarella, Matteo Bolchini, Gennaro Saporito, Licia Grazzi, Andrea Marcinnò, Gabriele Garascia, Enrico Grassi, Catello Vollono, Francesca Boscain, Martino Gentile, Andrea Burgalassi, Federico De Santis, Michele Corrado, Grazia Sances, Cristina Tassorelli, Maria Albanese, Michele Trimboli, Alberto Doretti

A robust multimodal brain MRI-based diagnostic model for migraine: validation across different migraine phases and longitudinal follow-up data

Jong Young Namgung, Eunchan Noh, Yurim Jang, Mi Ji Lee, Bo-yong Park

Consistency between headache diagnoses and ICHD-3 criteria across different levels of care

Lucas Hendrik Overeem, Marlene Ulrich, Mira Pauline Fitzek, Kristin Sophie Lange, Ja Bin Hong, Uwe Reuter, Bianca Raffaelli

Serial systemic immune inflammation indices: markers of acute migraine events or indicators of persistent inflammatory status?

Tissa Wijeratne, Melanie J. Murphy, Chanith Wijeratne, Paolo Martelletti, Leila Karimi, Vasso Apostolopoulos, Carmela Sales, Nina Riddell, Sheila G. Crewther

The burden of headache disorders among medical students in Vietnam: estimates from a cross-sectional study with a health-care needs assessment

Dung Viet Nguyen, Hieu Trung Vo, Khoi Hong Vo, Lam Tung Duong, Lam Que La, An Bao Hoang, Phu Hong Vo, Thao Thu Tran, Binh Van Phan, Huong Thi Thu Pham, Hai-Anh Nguyen, Nga Thi Bui, Phuc Duy Phan, Thang Xuan Pham, Cong-Hoang Nguyen, Ngoc-Linh Thi Pham, Luc Tien Trinh, Duong Thi Ha, Ha-An Phan, Thanh-Thuy Ho, Loi Thi Dinh, Le Thi Bich Nguyen, Linh Hue Nguyen, Toan Van Phan, Thuy Thanh Truong, Quy Huu Ha, Hoai Thi Thu Nguyen

Aura phenomenon: a proposal for an etiology-based clinical classification

  • Open Access
  • Aura
  • Review

Umberto Pensato, Andrew M. Demchuk, Jens P. Dreier, Kevin C. Brennan, Simona Sacco, Michele Romoli

Correction: Distinct expression profile reveals glia involvement in the trigeminal system attributing to post‑traumatic headache

Gurueswar Nagarajan, Yumin Zhang

Differentially localizing isoforms of the migraine component calcitonin gene-related peptide (CGRP), in the mouse trigeminal ganglion: βCGRP is translated but, unlike αCGRP, not sorted into axons

  • Open Access
  • Research

Sofia Lyng Wæver, Kristian Agmund Haanes

MRI-based analysis of the microstructure of the thalamus and hypothalamus and functional connectivity between cortical networks in episodic cluster headache

Chiara Abagnale, Antonio Di Renzo, Giada Giuliani, Gabriele Sebastianelli, Francesco Casillo, Lucia Ziccardi, Vincenzo Parisi, Cherubino Di Lorenzo, Mariano Serrao, Francesca Caramia, Vittorio Di Piero, Gianluca Coppola

Medication underuse in real-life practice: the impact of galcanezumab towards achieving very low frequency episodic migraine in a southeast Asian middle-income nation

Wanakorn Rattanawong, Prakit Anukoolwittaya, Akarin Hiransuthikul, Thanakit Pongpitakmetha, Auranee Trisataya, Sekh Thanprasertsuk, Alan Rapoport

Machine learning-driven identification of critical gene programs and key transcription factors in migraine

Lei Zhang, Yujie Li, Yunhao Xu, Wei Wang, Guangyu Guo

Headache after pediatric traumatic brain injury: a comparison between a post-acute sample of children and adolescents and general population

Marina Zeldovich, Leonie Krol, Katrin Cunitz, Christian Auer, Daniel Pinggera, Victoria Schön, Philipp Geiger, Joachim Suss, Inga K. Koerte, Emilie Isager Howe, Nada Andelic, Anna Buchheim, Matthias Gondan, Nicole von Steinbüchel

Increased TSPO alleviates neuropathic pain by preventing pyroptosis via the AMPK-PGC-1α pathway

Baolong Li, Kaiming Yu, Xiongyao Zhou, Jialu Sun, Le Qi, Weiye Li, Tuo Yang, Weizhen Li, Ningning Wang, Xiaosong Gu, Shusen Cui, Rangjuan Cao

Mechanisms underlying CSD initiation implicated by genetic mouse models of migraine

Daniela Pietrobon, K.C. Brennan

Correction: Filling the data gap on CGRP mAb therapy in low- to middle-income countries in Southeast Asia: insights from a real-world study in Thailand

Prakit Anukoolwittaya, Akarin Hiransuthikul, Thanakit Pongpitakmetha, Sekh Thanprasertsuk, Wanakorn Rattanawong

Effects of proton pump inhibitor (PPI) use on migraine – a critical review

Viktoria Tischler-Strasser, Irma Burdiladze, Goncalo Cabral, Esme Ekizoglu, Olga Grodzka, Keshet Pardo, Patryk Sochan, Laura Zaunandra, Antoinette MaassenVanDenBrink, Christian Lampl

Fitness-to-work considerations in the paradigmatic pain condition of headache disorder

Xiangning Fan, Ellina Lytvyak, Charl Els, Sebastian Straube

Revisiting substance P in migraine: a methodological approach inspired by anti-CGRP and anti-PACAP success

Lanfranco Pellesi, Lars Edvinsson

Exploring the association between statins use or HMG-CoA reductase inhibition and migraine: a systematic review and meta-analysis

Hamdy A. Makhlouf, Amr K. Hassan, Nereen A. Almosilhy, Ahmed S.A. Osman, Shrouk Ramadan, Moaz Elsayed Abouelmagd

Epidemiology of clinically significant migraine in Israel: a retrospective database study

A. Shifrin, E. Domany, M. Tirosh, D. Davidovici, S. Vinker, I. Forschner, A. Israel

The link between spreading depolarization and innate immunity in the central nervous system

Kadir Oguzhan Soylu, Muge Yemisci, Hulya Karatas

Shift from chronic to episodic migraine frequency in a long-term phase 3 study of galcanezumab

Hans-Christoph Diener, Kathleen A. Day, Sarah Lipsius, Sheena K. Aurora, Nada A. Hindiyeh, Holland C. Detke

Intracranial pressure monitoring in patients with spontaneous onset of orthostatic headache

Linda D’Antona, Sanjay Cheema, Dwij Mehta, Fion Bremner, Laurence Dale Watkins, Ahmed Kassem Toma, Manjit Singh Matharu

Headaches attributed to cranial and cervical artery dissections

Diana Doukhi, Stéphanie Debette, Jérome Mawet

Uncovering longitudinal changes in the brain functional connectome along the migraine cycle: a multilevel clinical connectome fingerprinting framework

Inês Esteves, Ana R. Fouto, Amparo Ruiz-Tagle, Gina Caetano, Rita G. Nunes, Nuno A. da Silva, Pedro Vilela, Isabel Pavão Martins, Raquel Gil-Gouveia, César Caballero-Gaudes, Patrícia Figueiredo

Effects of neck-exercise and health promotion on headache outcomes in office workers: secondary analysis of the NEXpro stepped wedge cluster randomised controlled trial

Markus J. Ernst, André Meichtry, Kerstin Luedtke, Andrea Aegerter, Aulona Ajeti, Marco Barbero, Beatrice Brunner, Samira Buob, Jon Cornwall, Yara Da Cruz, Manja Deforth, Oliver Distler, Julia Dratva, Holger Dressler, Tobias Egli, Achim Elfering, Irene Etzer-Hofer, Salome Felder, Ramona Furrer, David Gemperle, Michelle Gisler, Sandro Grob, Michelle Haas, Tabea Holzer, Delia Hug, Venerina Johnston, Sandro Klaus, Gina M. Kobelt, Hannu Luomajoki, Markus Melloh, Corinne Nicoletti, Seraina Niggli, Andrea Nüesch, Achim Nüssle, Kristina Ribeli, Salome Richard, Nadine Sax, Monika Schmid, Katja Schülke, Rebecca Siebeneicher, Gisela Sjøgaard, Lukas Staub, Seraina Störi, Thomas Volken, Josephine Wagner, Ellen Wartmann, Thomas Zweig, Deborah Falla

White matter alterations in episodic migraine without aura patients assessed with diffusion MRI: effect of free water correction

Irene Guadilla, Ana R Fouto, Amparo Ruiz-Tagle, Inês Esteves, Gina Caetano, Nuno A Silva, Pedro Vilela, Raquel Gil-Gouveia, Santiago Aja-Fernández, Patrícia Figueiredo, Rita G Nunes

Prediction models for treatment response in migraine: a systematic review and meta-analysis

Qiuyi Chen, Jiarun Zhang, Baicheng Cao, Yihan Hu, Yazhuo Kong, Bin Li, Lu Liu

Analysis of free-living daytime movement in patients with migraine with access to acute treatment

Jonas Van Der Donckt, Nicolas Vandenbussche, Mathias De Brouwer, Bram Steenwinckel, Marija Stojchevska, Femke Ongenae, Koen Paemeleire, Sofie Van Hoecke

Physical activity as a predictor of fremanezumab response in chronic migraine – the Phy-Fre-Mig study

Álvaro Sierra-Mencía, Andrea Recio-García, David García-Azorín, Antonio José Molina de la Torre, Isabel Ros González, Ángel Luis Guerrero-Peral

Safety and feasibility of deep brain stimulation of the anterior cingulate and thalamus in chronic refractory neuropathic pain: a pilot and randomized study

Denys Fontaine, Aurélie Leplus, Anne Donnet, Nelly Darmon, Anne Balossier, Bruno Giordana, Benoit Simonet, Petru Isan, Jean Regis, Michel Lanteri-Minet

The effect of calcitonin gene-related peptide monoclonal antibodies on restless legs syndrome in patients with migraine

Keisuke Suzuki, Shiho Suzuki, Hiroaki Fujita, Saro Kobayashi, Mukuto Shioda, Ryotaro Hida, Koichi Hirata

Stroke etiology and white matter burden in women with and without migraine

Anne E. Wilms, Nelleke van der Weerd, Thijs W. van Harten, Katie M. Linstra, Hendrikus J. A. van Os, Irene de Boer, Mark C. Kruit, Antoinette Maassen van den Brink, Marieke J. H. Wermer, Gisela M. Terwindt, Yolande Appelman, Sara Baart, Laura Benschop, Eric Boersma, Laura Brouwers, Ricardo Budde, Suzanne Cannegieter, Veerle Dam, Rene Eijkemans, Bart Fauser, Michel Ferrari, Arie Franx, Christianne de Groot, Marlise Gunning, Annemieke Hoek, Erik Koffijberg, Wendy Koster, Giske Lagerweij, Nils Lambalk, Joop Laven, Aad van der Lugt, Angela Maas, Cindy Meun, Saskia Middeldorp, Karel GM Moons, Bas van Rijn, Jeanine Roeters van Lennep, Jolien Roos-Hesselink, Luuk Scheres, Yvonne T. van der Schouw, Eric Steegers, Regine Steegers, Birgitta Velthuis, Bart Zick, Gerbrand Zoet

Correction: Headache frequency and neck pain are associated with trapezius muscle T2 in tension‑type headache among young adults

Nico Sollmann, Paul Schandelmaier, Dominik Weidlich, Jonathan Stelter, Gabby B. Joseph, Corinna Börner, Severin Schramm, Meinrad Beer, Claus Zimmer, Mirjam N. Landgraf, Florian Heinen, Dimitrios C. Karampinos, Thomas Baum, Michaela V. Bonfert

Migraine and stroke: correlation, coexistence, dependence - a modern perspective

Michał Borończyk, Anna Zduńska, Julia Węgrzynek-Gallina, Olga Grodzka, Anetta Lasek-Bal, Izabela Domitrz

Sex difference in TRPM3 channel functioning in nociceptive and vascular systems: an emerging target for migraine therapy in females?

Georgii Krivoshein, Eduardo Rivera-Mancilla, Antoinette MaassenVanDenBrink, Rashid Giniatullin, Arn M.J.M. van den Maagdenberg

Optogenetic inhibition of ventrolateral orbitofrontal cortex astrocytes facilitates ventrolateral periaqueductal gray glutamatergic activity to reduce hypersensitivity in infraorbital nerve injury rat model

Jaisan Islam, Md Taufiqur Rahman, Muhammad Ali, Hyong Kyu Kim, Elina KC, Young Seok Park

Pregnenolone sulfate potentiates tetrodotoxin-resistant Na+ channels to increase the excitability of dural afferent neurons in rats

Il-Sung Jang, Michiko Nakamura

Network meta-analysis comparing efficacy of different strategies on medication-overuse headache

Prut Koonalintip, Suppakorn Yamutai, Suwanna Setthawatcharawanich, Therdpong Thongseiratch, Ply Chichareon, Benjamin R. Wakerley

Optogenetic cortical spreading depression originating from the primary visual cortex induces migraine-like pain and anxiety behaviors in freely moving C57BL/6 J mice

Huijuan Yuan, Weinan Na, Bozhi Li, Shuai Miao, Wenjing Tang, Li Kang, Chenghui Pi, Chunxiao Yang, Wei Xie, Tao Wang, Deqi Zhai, Dengfa Zhao, Ruozhuo Liu, Shengyuan Yu

Burden of hidden migraine among the Arab general population: a cross-sectional study

Mohamed A. Elzayat, Shorouq A. Kassab, Mona A. F. Nada, Abdel-Hady El-Gilany

Advances in GLP-1 receptor agonists for pain treatment and their future potential

Yongtao He, Biao Xu, Mengna Zhang, Dan Chen, Shuyuan Wu, Jie Gao, Yongpeng Liu, Zixin Zhang, Junzhe Kuang, Quan Fang

Exploring vestibulocerebellum-vestibular nuclei-spinal trigeminal nucleus causals communication and TRPV2 ion channel in a mouse model of vestibular migraine

Qingling Zhai, Qihui Chen, Ning Zhang, Hongyan Li, Qijun Yu, Yonghui Pan

The burden of migraine and tension-type headache in Asia from 1990 to 2021

Yingzhu Zhao, Yujie Yi, Hong Zhou, Qian Pang, Jie Wang

The efficacy and safety of zavegepant nasal inhalation versus oral calcitonin-gene related peptide receptor antagonists in the acute treatment of migraine: a systematic review and network meta-analysis of the literature

Zixiang Zhu, Yanbing Tang, Longyuan Li, Hanyu Ni, Meirong Liu, Zhouqing Chen, Zhong Wang

Offset analgesia as a marker of dysfunctional pain modulation in episodic and chronic migraine

Giuseppe Cosentino, Elisa Antoniazzi, Camilla Cavigioli, Elena Guaschino, Natascia Ghiotto, Matteo Castaldo, Massimiliano Todisco, Roberto De Icco, Cristina Tassorelli

Efficacy and continuability of 675 mg fremanezumab administration over 2 years

Shohei Yoshida, Noboru Imai, Masato Keicho, Jun Kamimura, Asami Moriya, Nobuyasu Yagi, Rieko Suzuki, Takashi Konishi, Masahiro Serizawa

Temporomandibular disorders and mental health: shared etiologies and treatment approaches

Jiamin Wan, Jiu Lin, Tingfeng Zha, Francisco Ciruela, Shaokang Jiang, Zuping Wu, Xinyi Fang, Qianming Chen, Xiaoyan Chen

Headache types and characteristics in patients with Amyotrophic Lateral Sclerosis

Radwa Soliman, Nagia Fahmy, Mahmoud S. Swelam

Neuroimaging differences between chronic migraine with and without medication overuse headache: a 7 Tesla multimodal MRI study

Yin Sun, Longteng Ma, Song Wang, Caohui Duan, Xinyu Wang, Xiangbing Bian, Shuqing Wang, Deqi Zhai, Siyuan Xie, Shuhua Zhang, Yingyuan Liu, Xiaoxue Lin, Ruobing Wang, Xiu Liu, Shengyuan Yu, Xin Lou, Zhao Dong

Activation of central and peripheral transient receptor potential melastatin 8 increases susceptibility to spreading depolarization and facilitates trigeminal neuroinflammation

Tzu-Ting Liu, Pin-Yu Chen, Chyun-Yea Tseng, Yun-Ning Chen, Jian-Bang Chen, Tz-Han Ni, Shuu-Jiun Wang, Shih-Pin Chen, Jiin-Cherng Yen

The burden of headache disorders in Benin: national estimates from a population-based door-to-door survey

Thierry Adoukonou, Mendinatou Agbetou, Eric Dettin, Oyéné Kossi, Andreas Husøy, Dismand Houinato, Timothy J Steiner

Uncovering drug targets for cluster headache through proteome-wide Mendelian randomization analysis

  • Open Access
  • Research

Zhonghua Xiong, Zhi Guo, Lei Zhao, Dong Qiu, Yanliang Mei, Xiaoshuang Li, Peng Zhang, Mantian Zhang, Geyu Liu, Tianshuang Gao, Bendik S Winsvold, Aster V. E. Harder, Caroline Ran, Mona A Chalmer, Maria Carolina Dalmasso, Egil Ferkingstad, Kumar Parijat Tripathi, Elena Bacchelli, Sigrid Børte, Carmen Fourier, Anja S Petersen, Lisanne S Vijfhuizen, Sigurdur H Magnusson, Emer O’Connor, Gyda Bjornsdottir, Paavo Häppölä, Yen-Feng Wang, Ida Callesen, Tim Kelderman, Victor J Gallardo, Irene de Boer, Felicia Jennysdotter Olofsgård, Katja Heinze, Nunu Lund, Laurent F Thomas, Chia-Lin Hsu, Matti Pirinen, Heidi Hautakangas, Marta Ribasés, Simona Guerzoni, Prasanth Sivakumar, Janice Yip, Axel Heinze, Fahri Küçükali, Sisse R Ostrowski, Ole B Pedersen, Espen S Kristoffersen, Amy E Martinsen, María S Artigas, Susie Lagrata, Maria Michela Cainazzo, Joycee Adebimpe, Olivia Quinn, Carl Göbel, Anna Cirkel, Alexander E Volk, Stefanie Heilmann-Heimbach, Anne Heidi Skogholt, Maiken E Gabrielsen, Leopoldine A Wilbrink, Daisuke Danno, Dwij Mehta, Daníel F Guðbjartsson, Frits R. Rosendaal, Ko Willems van Dijk, Rolf Fronczek, Michael Wagner, Martin Scherer, Hartmut Göbel, Kristel Sleegers, Olafur A. Sveinsson, Luca Pani, Michele Zoli, Josep A. Ramos-Quiroga, Efthimios Dardiotis, Anna Steinberg, Steffi Riedel-Heller, Christina Sjöstrand, Thorgeir E. Thorgeirsson, Hreinn Stefansson, Laura Southgate, Richard C. Trembath, Jana Vandrovcova, Raymond Noordam, Koen Paemeleire, Kari Stefansson, Cathy Shen-Jang Fann, Elisabet Waldenlind, Erling Tronvik, Rigmor H. Jensen, Shih-Pin Chen, Henry Houlden, Gisela M. Terwindt, Christian Kubisch, Elena Maestrini, Michail Vikelis, Patricia Pozo-Rosich, Andrea C. Belin, Manjit Matharu, Arn M.J.M. van den Maagdenberg, Thomas F. Hansen, Alfredo Ramirez, John-Anker Zwart, Yonggang Wang, Xueying Yu

Assessment of sleep patterns in migraine sufferers using the Epworth Sleepiness Scale

Arman Hajikarim-Hamedani, Setareh Rassa, Termeh Tarjoman, Mehran Shafiei

The Global Campaign against Headache, aged 21: a critical self-appraisal, and plans for phase 2

Timothy J. Steiner, Raquel Gil-Gouveia, Andreas K. Husøy, Rigmor Jensen, Zaza Katsarava, Paolo Martelletti, Lars Jacob Stovner, Derya Uluduz

Effects of acute sleep deprivation on the brain function of individuals with migraine: a resting-state functional magnetic resonance imaging study

Shuqing Wang, Longteng Ma, Song Wang, Caohui Duan, Xinyu Wang, Xiangbing Bian, Deqi Zhai, Yin Sun, Siyuan Xie, Shuhua Zhang, Yingyuan Liu, Xiaoxue Lin, Ruobing Wang, Xiu Liu, Shengyuan Yu, Xin Lou, Zhao Dong

Transcutaneous occipital nerve stimulation alleviated migraine related pain by regulating synaptic plasticity and CGRP expression in the periaqueductal gray of male rats

Yinglu Liu, Shengli Guo, Yang Li, Jingrui Mao, Xiaoxue Lin, Ruozhuo Liu, Dengfa Zhao, Zhao Dong, Shengyuan Yu, Xun Han

Differential fMRI neural synchrony associated with migraine during naturalistic stimuli with negative emotional valence

Keva Klamer, Joshua Craig, Christina Haines, KiAnna Sullivan, Peter Seres, Chelsea Ekstrand

Association between proton pump inhibitor use and migraine: a systematic review and meta-analysis

Prakasini Satapathy, Mahalaqua Nazli Khatib, Nasir Vadia, Soumya V. Menon, Kattela Chennakesavulu, Rajashree Panigrahi, Muhammed Shabil, Mahendra Singh, Sanjit Sah, Doddolla Lingamaiah, Khang Wen Goh, Edward Mawejje, Ganesh Bushi

Is migraine a common manifestation of CADASIL? Arguments Pros

Hugues Chabriat

Is migraine a common manifestation of CADASIL-Cons

Yen-Feng Wang

Correction: Combining treatments for migraine prophylaxis: the state‑of‑the‑art

Lanfranco Pellesi, David Garcia‑Azorin, Eloisa Rubio‑Beltrán, Wook‑Seok Ha, Roberta Messina, Raffaele Ornello, Igor Petrusic, Bianca Raffaelli, Alejandro Labastida‑Ramirez, Ruth Ruscheweyh, Claudio Tana, Doga Vuralli, Marta Waliszewska‑Prosół, Wei Wang, William Wells‑Gatnik

Artificial neural networks applied to somatosensory evoked potentials for migraine classification

Gabriele Sebastianelli, Daniele Secci, Francesco Casillo, Chiara Abagnale, Cherubino Di Lorenzo, Mariano Serrao, Shuu-Jiun Wang, Fu-Jung Hsiao, Gianluca Coppola

Associations between personality traits and pain experiences in trigeminal neuralgia

Jeong-A Lee, Yoon Kyung Han, Won Je Jung, Byung H. Lee, Seunghoon Lee

Limbic system abnormalities in episodic cluster headache: a 7T MRI multimodal study

Xinyu Wang, Luhua Zhang, Yongqin Xiong, Mengmeng Hou, Shuhua Zhang, Caohui Duan, Song Wang, Xiaoyu Wang, Haoxuan Lu, Jiayu Huang, Yan Li, Zhixuan Li, Zhao Dong, Xin Lou

Prediction of new-onset migraine using clinical-genotypic data from the HUNT Study: a machine learning analysis

Fahim Faisal, Antonios Danelakis, Marte-Helene Bjørk, Bendik Winsvold, Manjit Matharu, Parashkev Nachev, Knut Hagen, Erling Tronvik, Anker Stubberud

Cluster headache diagnostic delay and its predictors: a systematic review with a meta-analysis

E. K. Van Obberghen, R. Fabre, M. Lanteri-Minet

Prioritising patient involvement in patient reported outcome measures– a PROMising way to improve headache care

  • Open Access
  • Review

Lakshini Gunasekera, Jason C. Ray, Neha Kaul, Helmut Butzkueven, Elspeth Hutton, Terence J. O’Brien

Biomarkers in headaches as a potential solution to simplify differential diagnosis of primary headache disorders: a systematic review

Olga Grodzka, Wiktor Łagowski, Ceren Eyileten, Izabela Domitrz

Association between mental disorders and trigeminal neuralgia: a cohort study and Mendelian randomization analysis

Jianke Wang, Mingxiao Li, Ze Zhang, Yu Duan, Ziyi Zhang, Hanlin Liu, Ke Yang, Jiang Liu

Lower spinal levels and male sex are associated with greater epidural blood patch volume in spontaneous intracranial hypotension

Woo-Seok Ha, JaeWook Jeong, Seungwon Song, Jungyon Yum, Soomi Cho, Hee Jung Kim, Min Kyung Chu

Overview of migraine care, impact of the disease, and patient experience in France through patient voices: a cross-sectional and participatory survey study

Anne Duburcq, Manon Molins, Sabine Debremaeker, Julie Joie, Luna Lopes, Camille Nevoret, Olivia Begasse de Dhaem

Migraine with and without aura—two distinct entities? A narrative review

Olga Grodzka, Ketevan Dzagoevi, Tayla Rees, Goncalo Cabral, Piotr Chądzyński, Stefano Di Antonio, Patryk Sochań, Antoinette MaassenVanDenBrink, Christian Lampl

Differences in pharmacological migraine treatment across different levels of clinical headache care – a cross-sectional study

Mira Pauline Fitzek, Lucas Hendrik Overeem, Marlene Ulrich, Ja Bin Hong, Carolin Luisa Hoehne, Kristin Sophie Lange, Yones Salim, Uwe Reuter, Bianca Raffaelli

PACAP38-induced migraine attacks are independent of CGRP signaling: a randomized controlled trial

Mohammad Al-Mahdi Al-Karagholi, Zixuan Alice Zhuang, Signe Beich, Håkan Ashina, Messoud Ashina

Efficacy and safety of ultrasound-guided peripheral nerve blocks in management of chronic resistant migraine

Nourhan Abdelmohsen Taha, Mai Fathy, Ahmed Elsadek, Tamer Hussein Emara, Sherien Mohamed Farag, Ramez Reda Moustafa, Mohamad Osama Abdulghani

Correction: Network meta‑analysis comparing efficacy of different strategies on medication‑overuse headache

Prut Koonalintip, Suppakorn Yamutai, Suwanna Setthawatcharawanich, Therdpong Thongseiratch, Ply Chichareon, Benjamin R. Wakerley

The association between endometriosis and migraine: a systematic review and meta-analysis of observational studies

Giorgia Elisabeth Colombo, Sofia Makieva, Edgardo Somigliana, Georgios Schoretsanitis, Brigitte Leeners, Christian Polli, Noemi Salmeri, Dimitrios Rafail Kalaitzopoulos, Paola Vigano’

Adoption of rimegepant in Denmark: a register-based study on uptake, prescribing patterns and initiator characteristics

Lanfranco Pellesi, Thien Phu Do, Martin Thomsen Ernst, Jesper Hallas, Anton Pottegård

Enhancement of the endocannabinoid system through monoacylglycerol lipase inhibition relieves migraine-associated pain in mice

Elizaveta Mangutov, Yaseen Awad-Igbaria, Kendra Siegersma, Francois Gastambide, Ayodeji A. Asuni, Amynah A. A. Pradhan

Inhibition of endocannabinoid hydrolases MAGL, FAAH and ABHD6 by AKU-005 reduces ex vivo cortical spreading depression

Flavia Brugia, Konstantin Ivanov, Auni Aroviita, Raisa Giniatullina, Marko Lehtonen, Tarja Malm, Juha Savinainen, Rashid Giniatullin, Adriana Della Pietra

Plasma SuPAR and therapeutic response to erenumab in migraine: a REFORM study

William K. Karlsson, Rune H. Christensen, Haidar M. Al-Khazali, Thomas Kallemose, Baker N. Jawad, Ove Andersen, Messoud Ashina, Håkan Ashina

Transient focal neurological symptoms and headache: is it TIA or migraine with aura?

Elena R. Lebedeva, Jes Olesen

Increased infection risk in patients on preventive CGRP-targeting therapies– a meta-analysis and clinical effect assessment

Marcin Straburzyński, Daria Kopyt, Karol Marschollek, Bartłomiej Błaszczyk, Ewa Kuca-Warnawin, Weronika Kurowska, Błażej Misiak, Kuan-Po Peng, Marta Waliszewska-Prosół, Arne May

Beyond the “string of beads”: case-based exploration of diagnostic pitfalls and solutions in reversible cerebral vasoconstriction syndrome

Seung Ae Kim, Eung Yeop Kim, Shuu-Jiun Wang, Mi Ji Lee

Is there a role of calcitonin gene-related peptide in cortical spreading depression mechanisms?– Argument pro

Marina Romozzi, Paolo Calabresi

Is there a role of calcitonin gene-related peptide in cortical spreading depression mechanisms?– argument con.

  • Open Access
  • Aura
  • Comment

Agustin Melo-Carrillo

Migraine and increased cardiovascular disease risk: interaction with traditional risk factors and lifestyle factors

Ying Huang, Wen Yan, Yifan Jia, Qingfang Xie, Yuexiu Lei, Zepeng Chen, Yanjie Zhou, Zheman Xiao

Tolerability of repetitive dihydroergotamine infusions paired with an adjustment in preventive treatment strategy in chronic headache disorders in children and youth

Sara Pavitt, Cynthia Morris, Lauren Shin, Andrew Jones, Beata Vayngortin, Natalia Zorrilla, Chengshi Jin, Isabel Allen, Amy A. Gelfand

Correction: Uncovering drug targets for cluster headache through proteome-wide Mendelian randomization analysis

Zhonghua Xiong, Zhi Guo, Lei Zhao, Dong Qiu, Yanliang Mei, Xiaoshuang Li, Peng Zhang, Mantian Zhang, Geyu Liu, Tianshuang Gao, Bendik S. Winsvold, Aster V. E. Harder, Caroline Ran, Mona A Chalmer, Maria Carolina Dalmasso, Egil Ferkingstad, Kumar Parijat Tripathi, Elena Bacchelli, Sigrid Børte, Carmen Fourier, Anja S Petersen, Lisanne S Vijfhuizen, Sigurdur H Magnusson, Emer O’Connor, Gyda Bjornsdottir, Paavo Häppölä, Yen-Feng Wang, Ida Callesen, Tim Kelderman, Victor J Gallardo, Irene de Boer, Felicia Jennysdotter Olofsgård, Katja Heinze, Nunu Lund, Laurent F Thomas, Chia-Lin Hsu, Matti Pirinen, Heidi Hautakangas, Marta Ribasés, Simona Guerzoni, Prasanth Sivakumar, Janice Yip, Axel Heinze, Fahri Küçükali, Sisse R Ostrowski, Ole B Pedersen, Espen S Kristoffersen, Amy E Martinsen, María S Artigas, Susie Lagrata, Maria Michela Cainazzo, Joycee Adebimpe, Olivia Quinn, Carl Göbel, Anna Cirkel, Alexander E Volk, Stefanie Heilmann-Heimbach, Anne Heidi Skogholt, Maiken E Gabrielsen, Leopoldine A Wilbrink, Daisuke Danno, Dwij Mehta, Daníel F Guðbjartsson, Frits R. Rosendaal, Ko Willems van Dijk, Rolf Fronczek, Michael Wagner, Martin Scherer, Hartmut Göbel, Kristel Sleegers, Olafur A. Sveinsson, Luca Pani, Michele Zoli, Josep A. Ramos-Quiroga, Efthimios Dardiotis, Anna Steinberg, Steffi Riedel-Heller, Christina Sjöstrand, Thorgeir E. Thorgeirsson, Hreinn Stefansson, Laura Southgate, Richard C. Trembath, Jana Vandrovcova, Raymond Noordam, Koen Paemeleire, Kari Stefansson, Cathy Shen-Jang Fann, Elisabet Waldenlind, Erling Tronvik, Rigmor H. Jensen, Shih-Pin Chen, Henry Houlden, Gisela M. Terwindt, Christian Kubisch, Elena Maestrini, Michail Vikelis, Patricia Pozo-Rosich, Andrea C. Belin, Manjit Matharu, Arn M. J. M. van den Maagdenberg, Thomas F. Hansen, Alfredo Ramirez, John-Anker Zwart, Yonggang Wang, Xueying Yu

Calcitonin gene-related peptide in newly diagnosed idiopathic intracranial hypertension: a prospective, cross-sectional, case-control study of cerebrospinal fluid and plasma

Nadja Skadkær Hansen, Johanne Juhl Korsbaek, Lasse Kristoffer Bak, Niklas Rye Jørgensen, Dagmar Beier, Rigmor Højland Jensen

Signaling pathways and molecular mechanisms involved in the onset and progression of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL); a focus on Notch3 signaling

Parasta Heidari, Motahareh Taghizadeh, Omid Vakili

Inhibition of S100A4 decreases neurotoxic astrocyte reactivity and attenuates neuropathic pain via the TLR4/NF-κB pathway in a rat model of spinal nerve ligation

Tao Xue, Yu Song, Jie Zhao, Guiyong Fan, Zhiyuan Liu

Who is the patient with resistant myofascial temporomandibular disorders pain? A somatosensory, psychosocial, and genetic characterization

  • Open Access
  • Research

Giancarlo De la Torre Canales, Rodrigo Lorenzi Poluha, Flávia Fonseca Carvalho Soares, Dyna Mara Araújo Oliveira Ferreira, Alfonso Sánchez-Ayala, Leonardo Rigoldi Bonjardim, Malin Ernberg, Paulo César Rodrigues Conti

Safety, efficacy, and compliance of moderate-to-high dose eptinezumab and erenumab in chronic migraine patients with medication-overuse headache: an updated systematic review and meta-analysis

Nhan Nguyen, Vinh Ho Quang Tri, Vy Nguyen Ngoc Dan , Nghi Bao Tran, Laszlo Olah, Mate Heja

The role of community pharmacists in managing common headache disorders, and their integration within structured headache services: position statement on behalf of the European Headache Federation (EHF) and Lifting The Burden (LTB: the Global Campaign against Headache), with the formal endorsement of the International Pharmaceutical Federation

  • Open Access
  • Headache
  • Consensus Article

Heba BaniHani, Christian Lampl, Antoinette MaassenvandenBrink, Faisal Mohammad Amin, Louise Ninett Carlsen, Gianluca Coppola, Christina Deligianni, Raquel Gil-Gouveia, Philip R. Holland, Andreas K. Husøy, Rigmor Jensen, Madalena Plácido, Uwe Reuter, Kristina Ryliškienė, Margarita Sanchez del Río, Henrik Winther Schytz, Erling Tronvik, Jan Versijpt, Timothy J. Steiner

Unmasking the relationship between CGRP and glutamate: from peripheral excitation to central sensitization in migraine

Fahimeh Martami, Kathleen F. Holton

Efficacy of monoclonal antibodies against CGRP in migraine patients with fibromyalgia comorbidity: a retrospective monocentric observational study

Marina de Tommaso, Stefania Scannicchio, Giulia Paparella, Livio Clemente, Giuseppe Libro

Unveiling new insights into migraine risk stratification using machine learning models of adjustable risk factors

Yu-Chen Liu, Ye-Hai Liu, Hai-Feng Pan, Wei Wang

The burden of migraine and predictions in the Asia–Pacific region, 1990–2021: a comparative analysis of China, South Korea, Japan, and Australia

Yun-Xia Wang, Guang-Shuang Lu, Jin-Jing Zhao, Wei Dai, Na Zheng, Guo-En Yao, Ruo-Zhuo Liu

Lateral habenula-rostromedial tegmental nucleus circuit mediates inflammatory pain in mice

  • Open Access
  • Research

Yanfei Sun, Jing Cao, Chunpeng Xu, Jiangtao Sun, Xiaofeng Liu, Zhenguang Shi, SiMeng An, Danyang Zhao, Dongjie Sun, Xuxin Wang, Guoyan Zhao, Chi Zhang, Guangjian Li, Jinyu Xiao, Jing Yang, Hua Zhao

Headache-attributed burden and a health-care needs assessment in Delhi and National Capital Region of India: estimates from a cross-sectional population-based study

Anand Krishnan, Debashish Chowdhury, Ashish Duggal, Ritvik Amarchand, Andreas Husøy, Timothy J. Steiner

Real-world use of over-the-counter medications by patients with migraine in Japan: results from the OVERCOME (Japan) 2nd study

Ryotaro Ishii, Tsubasa Takizawa, Shiho Suzuki, Daisuke Danno, Moemi Miura, Yoshinori Tanizawa, Satoshi Osaga, Chie Hashimoto, Mika Komori

Altered aminoacid and lipid metabolism in a rat orofacial inflammation model determined by omics approach: potential role in trigeminal sensitisation

Krisztina Takács-Lovász, Timea Aczél, Violetta Mohos, Máté Harmath, Jennet Pirkuliyeva, Gellért Karvaly, Róbert Farkas, Michal Ciborowski, Joanna Godzien, Kata Bölcskei, József Kun, Zsuzsanna Helyes

The interictal transcriptomic map of migraine without aura

Peter Petschner, Sahel Kumar, Duc A. Nguyen, Dora Torok, Zsofia Gal, Daniel Baksa, Kinga Gecse, Gyongyi Kokonyei, Hiroshi Mamitsuka, Gabriella Juhasz

The role and interaction of hypothalamic-related neurotransmitters in migraine

Ana Belen Salinas-Abarca, Mohammed Gamal-Eltrabily, Marcela Romero-Reyes, Simon Akerman

Correction: Inhibition of endocannabinoid hydrolases MAGL, FAAH and ABHD6 by AKU‑005 reduces ex vivo cortical spreading depression

  • Open Access
  • Correction

Flavia Brugia, Konstantin Ivanov, Auni Aroviita, Raisa Giniatullina, Marko Lehtonen, Tarja Malm, Juha Savinainen, Rashid Giniatullin, Adriana Della Pietra

Differential inhibitory effects of endocannabinoids on neuronal firing of mouse meningeal afferents

Georgii Krivoshein, Adriana Della Pietra, Juha Savinainen, Arn M. J. M. van den Maagdenberg, Rashid Giniatullin

Unraveling the paradox: cardiovascular risk profiling in migraine– a correspondence

Linda Al-Hassany, Ruben W. A. van Drie, Deirdre M. Boucherie, Antoinette MaassenVanDenBrink

Burden of migraine among Egyptian people: prevalence and comorbidities

Ahmed Amir Samir, Ahmed W. Hageen, Ahmed Elgammal, Mostafa Meshref, Mennatullah A. El-Refaay, Mohamed Medhat Taalap, Ali Elsaeed Nassef, Rawan Ali Bedewe, Ahmed Almeldein, Ibrahim Ali Kabbash

White matter and cortical gray matter microstructural alterations in migraine: a NODDI and DTI analysis

Zhilei Li, Yanliang Mei, Lei Wang, Tianhua Fan, Cheng Peng, Kaibo Zhang, Shouyi Wu, Tong Chen, Zhenchang Zhang, Binbin Sui, Yonggang Wang, Xueying Yu

Astrocytic spermidine insufficiency contributes to enhanced pain sensitivity associated with ApoE4

Kaiming Yu, Xiongyao Zhou, Baolong Li, Jialu Sun, Tuo Yang, Weizhen Li, Ningning Wang, Xiaosong Gu, Shusen Cui, Rangjuan Cao

Prevalence, disability, and economic impact of migraine in Spain: a nationwide population-based study

Margarita Sanchez-del-Rio, David García-Azorín, Carmen Peral, Beatriz Armada, Pablo Irimia-Sieira, Jesus Porta-Etessam

Nuclear paraspeckle assembly transcript 1 promotes photophobia behavior in mice via miR-196a-5p/Trpm3 coupling

Zhuoan Huang, Xingshen Li, Xiaolin Wang, Jiaqi Wu, Ziyang Gong, Sulev Kõks, Minyan Wang

Substance P release from rat dura mater is inversely correlated with CGRP release– experiments using glycerol trinitrate and anti-CGRP antibodies

Mária Dux, Karl Messlinger

The impact of CSF venous fistula embolization on patient’s quality of life, a longitudinal clinical-radiological exploration

Malo Goapper, Liesjet E.H. van Dokkum, Vincent Costalat, Gaetano Risi, Lucas Corti, Olivia Portalier, Nicolas Lonjon, Emmanuelle Le Bars, Anne Ducros, Federico Cagnazzo

Dysfunctional mesocorticolimbic circuitry in cluster headache

Stefania Ferraro, Greta Demichelis, Jean Paul Medina Carrion, Dan Liu, Benjamin Becker, Michael Maes, Davide Fedeli, Giuseppe Ciullo, Susanna Usai, Marina Grisoli, Luisa Chiapparini, Alberto Cecchini Proietti, Luca Giani, Anna Nigri, Massimo Leone

GIANT: a prospective, multicenter, real-world study on the effectiveness, safety, and tolerability of atogepant in migraine patients with multiple therapeutic failures

Piero Barbanti, Gabriella Egeo, Francesca Pistoia, Cinzia Aurilia, Paola Scatena, Steno Rinalduzzi, Silvia Strumia, Antonio Salerno, Fabio Frediani, Andrea Galli, Massimo Autunno, Laura Di Clemente, Maurizio Zucco, Maria Albanese, Francesco Bono, Pietrantonio Bruno, Laura Borrello, Stefano Messina, Alberto Doretti, Angelo Ranieri, Cecilia Camarda, Rosario Vecchio, Valeria Drago, Giulia Fiorentini, Carlo Tomino, Stefano Bonassi, Paola Torelli, Alice Mannocci, Marco Aguggia, Gennaro Alfieri, Diletta Alivernini, Raffaella Ardau, Maria Letizia Bartolozzi, Maria Carmela Bloise, Simone Braca, Antonio Bruno, Stefano Caproni, Ilaria Cetta, Alessandra Cherchi, Bruno Colombo, Eleonora Colombo, Alfonso Coppola, Domenico Cosenza, Francesca Cortese, Matteo De Bartolo, Roberto De Simone, Arianna Deidda, Alessandra Del Bene, Gianluca Demirtzidis, Alfonsina Di Summa, Valentina Favoni, Ludovica Ferraù, Isabella Ferdinanda Pestalozza, Cinzia Finocchi, Annalisa Gai, Rosario Grugno, Martina Guarinoni, Elisabetta Iannaccone, Giovanni Idone, Vincenzo Laterza, Riccardo Lo Presti, Luca Lombardi, Irene Madonia, Andrea Mancioli, Sara Matignaro, Silvia Nizzoli, Matteo Paolucci, Maristella Piccininni, Pietro Querzani, Simone Quintana, Micaela Robotti, Pamela Rosettani, Marco Russo, Sergio Salvemini, Giuliano Sette, Gabriele Sixt, Michela Sforza, Martina Sodano, Giorgio Spano, Maria Erminia Stochino, Denise Tedeschi, Rossana Terlizzi, Valentina Teresi, Daniela Ungaro, Fabio Valguarnera, Gianluca Vita, Laura Zanandrea

Induction of more severe central sensitization in a medication overuse headache model mice through active ingestion of rizatriptan

Zhenjie Ma, Chenhao Li, Wenhao Bai, Wei Xie, Mingjie Zhang, Han Xiao, Cancan Chen, Yang Li, Wenwen Zhang, Deqi Zhai, Yingyuan Liu, Dengfa Zhao, Wenjing Tang, Zhao Dong, Ruozhuo Liu, Shengyuan Yu

Genetic influence of the brain imaging phenotypes, brain and cerebrospinal fluid metabolites and brain genes on migraine subtypes: a Mendelian randomization and multi-omics study

Ping-An Zhang, Jie-Lin Wang, Mei-Hua Dong, Xiang-Chun Huang, Nai-Jian Li, Run-Dong Qin, Jing Li

Unravelling the gut-brain connection: a systematic review of migraine and the gut microbiome

Caroline W Mugo, Ella Church, Richard D Horniblow, Susan P Mollan, Hannah Botfield, Lisa J Hill, Alexandra J Sinclair, Olivia Grech

Reliability and validity of the Arabic version of cluster headache impact questionnaire in both active episodic and chronic cluster headache

Mona Hussein, Mona AF Nada, Amr Hassan, Mohamed Abdelghaffar, Mona Ali, Alaa Elmazny, Rehab Magdy

Ergotamine enhances circadian amplitude and diurnally mitigates nitroglycerin-induced mechanical hypersensitivity

Chorong Han, Hwayoung Baek, Ji Ye Lim, Eunju Kim, Celia K. Tran, Emma Freeman, Zheng Chen, Seung-Hee Yoo, Mark J. Burish

Validation of an 8-item self-administered questionnaire for assessing migraine-related sensory hypersensitivities (MHQ-8)

François Gabrielli, Melissa Zuel, Camille Magaud, Sophia Sickout-Arondo, Bruno Pereira, Jérémie Dassa, Solène De Gaalon, Geneviève Demarquay, Anne Donnet, Anne Ducros, Pierric Giraud, Evelyne Guégan-Massardier, Christian Lucas, Jérôme Mawet, Mitra Najjar, Caroline Roos, Elise K. Van Obberghen, Christian Dualé, Radhouane Dallel, Xavier Moisset

Association between headaches and lifestyle factors and physical and mental symptoms among 63,071 workers at a Japanese information technology company

Masako Yokoyama, Hisaka Igarashi, Hirohisa Kato, Tetsuji Yokoyama, Hiroshi Ebihara, Yasuhiro Azuma, Fumihiko Sakai, Hitoshi Miyake, Satoko Nagumo

Fibroblast reprogramming in the dura mater of NTG-induced migraine-related chronic hypersensitivity model drives monocyte infiltration via Angptl1-dependent stromal signaling

Guangyu Guo, Lei Zhang, Xuyang Liu, Yiping Deng, Peiyu Wu, Ruofan Zhao, Wei Wang

Expert consensus on gepants for acute and preventive treatment of migraine in Thailand

  • Open Access
  • Migraine
  • Consensus Article

Prakit Anukoolwittaya, Wanakorn Rattanawong, Kiratikorn Vongvaivanich, Thanakit Pongpitakmetha, Sekh Thanprasertsuk, Thaninjitra Poonpedpun, Pannathat Soontrapa, Kanokrat Suwanlaong, Kannikar Kongbunkiat, Surasak Komonchan, Petcharat Dusitanond, Chutithep Teekaput, Nopdanai Sirimaharaj, Nadolporn Yuvasilp, Surat Tanprawate

Impaired glymphatic function contributes to high-frequency attacks in patients with episodic migraine

Xin Cai, Wei Sun, Mengfei Cai, Dawei Li, Zhenzhen Chen, Hao Li, Bo Yuan, Yan Li, Zaiyi Liu, Yuhu Zhang

Smoking in primary headaches – a systematic review and meta-analysis

Bartłomiej Błaszczyk, Helena Martynowicz, Jakub Przegrałek, Piotr Niemiec, Marcin Straburzyński, Sławomir Budrewicz, Marta Waliszewska-Prosół

The lactylation–immune regulatory axis: a potential therapeutic target for migraine prevention and treatment

Liu Wang, Zhixuan Lan, Ying He, Yue Cheng, Ruilin He, Zongbin Jiang

Association of the total cholesterol to high-density lipoprotein cholesterol ratio with all-cause mortality risk in the migraine population

Zhao-Xuan Lu, Bing-Qing Dong, Liang Chen, Heng-Le Wei

Migraine is a risk factor for dementia: a systematic review and meta-analysis of cohort studies

Wenyan Zhu, Yijun Zhan, Jian Pei, Qinhui Fu, Ruiqi Wang, Qianwen Yang, Qingyang Guan, Like Zhu

Regional and whole-brain neurofunctional alterations during pain empathic processing of physical but not affective pain in migraine patients

Dan Liu, Menghan Li, Heng Jiang, Yiqi Mi, Xiaolei Xu, Yali Zhou, Yaxian Hou, Yuquan Shen, Michael Maes, Xiao Xiao, Feng Zhou, Luca Giani, Keith M. Kendrick, Benjamin Becker, Stefania Ferraro

Correction: The role of community pharmacists in managing common headache disorders, and their integration within structured headache services: position statement on behalf of the European Headache Federation (EHF) and Lifting The Burden (LTB: the Global Campaign against Headache), with the formal endorsement of the International Pharmaceutical federation

Heba BaniHani, Christian Lampl, Antoinette MaassenvandenBrink, Faisal Mohammad Amin, Louise Ninett Carlsen, Gianluca Coppola, Christina Deligianni, Raquel Gil‑Gouveia, Philip R. Holland, Andreas K. Husøy, Rigmor Jensen, Madalena Plácido, Uwe Reuter, Kristina Ryliškienė, Margarita Sanchez del Río, Henrik Winther Schytz, Erling Tronvik, Jan Versijpt, Timothy J. Steiner

The dual impact of ictal and interictal burden in migraine: an analysis from the ObserVational survey of the Epidemiology, tReatment, and Care Of MigrainE (OVERCOME) Japan second study

Tsubasa Takizawa, Daisuke Danno, Ryotaro Ishii, Shiho Suzuki, Moemi Miura, Yoshinori Tanizawa, Satoshi Osaga, Michio Okada, Chie Hashimoto, Mika Komori

Ex vivo stimulation of the trigeminal nucleus caudalis induces peripheral CGRP release in the trigeminal ganglion and reveals a distinct dopamine–endocannabinoid mechanism relevant to migraine

Isabella Mai Christiansen, Philip Victor Reducha, Lars Edvinsson, Anja Holm, Kristian Agmund Haanes

RAMP1-dependent hormonal regulation of CGRP and its receptor in the trigeminal ganglion

Anja Holm, Jacob C. A. Edvinsson, Diana N. Krause, Lars Edvinsson

Emerging treatments for chronic neuropathic pain from a cross-disease perspective: developments and applications of nanomaterials

Rui Sun, Xiaoqin Zhang, Tao Dou, Zhiyi Xiao, Xiaoran Deng

Inverse association of obesity with bout periodicity in episodic cluster headache: a multicenter cross-sectional study

Byung-Su Kim, Mi Ji Lee, Byung-Kun Kim, Jong-Hee Sohn, Tae-Jin Song, Min Kyung Chu, Soo-Kyoung Kim, Jeong Wook Park, Heui-Soo Moon, Pil-Wook Chung, Soo-Jin Cho

Migraine through puberty and menopausal transition—data from the population-based Norwegian Women and Health study (NOWAC)

Nora Stensland Bugge, Kjersti Grøtta Vetvik, Karl Bjørnar Alstadhaug, Tonje Braaten

Cold receptor TRPM8 as a target for migraine-associated pain and affective comorbidities

David Cabañero, Edward P. Carter, Rafael González-Cano, Enrique J. Cobos, Asia Fernández-Carvajal, Antonio Ferrer-Montiel

Adverse events associated with gepants: a pharmacovigilance analysis based on the FDA adverse event reporting system

Qi Song, Siyuan Gao, Yaqian Tan

Glymphatic dysfunction in classical trigeminal neuralgia: DTI-ALPS index stratification from healthy controls to post-MVD

Xiaolin Hou, Bo Wu, Ruxiang Xu, Cheng Yin

What does a migraine aura look like?—A systematic review

  • Open Access
  • Aura
  • Review

Ľubica Joppeková, Maria João Pinto, Mariana Dias da Costa, Richard Boček, Gabriele Berman, Yones Salim, Dinara Akhtanova, Aizhana Abzalbekova, Antoinette MaassenVanDenBrink, Christian Lampl

High prevalence of primary headaches among patients with post-traumatic stress disorder: an observational study of consecutive patients

Hugues Magne, Bruno Pereira, Xavier Moisset

Identification of comorbid genes between type 2 diabetes and migraine through peripheral blood single-cell and Mendelian randomization analysis

  • Open Access
  • Research

Bobo Yuan, Jianrui Li, Qing Shu, Xiaoye Wang, Guogang Luo, Ranran Ma

Tolerability of switch from erenumab to fremanezumab in adults with chronic migraine: a 3-month, single-center, prospective, real-world, observational study

Faisal Mohammad Amin, Thor Linnet, Christopher Kjaer Cullum, Thien Phu Do, Samaira Younis

Prevalence, characteristics and management of migraine patients with triptan failure in primary care: the EMR France-Mig study

M. Lanteri-Minet, C. Casarotto, O. Bretin, C. Collin, M. Gugenheim, V. Raclot, A. Cases, P. A. Squara, W. Aissani, A. Saighi, H. Lefebvre

Shared neural signatures of photophobia in migraine and post-traumatic headache: a task-based fMRI study

Rune Häckert Christensen, Haidar Muhsen Al-Khazali, Anna Gudrun Melchior, Messoud Ashina, Håkan Ashina

White matter tract differences in persistent post-traumatic headache, migraine, and healthy controls: a diffusion tensor imaging study

Rune Häckert Christensen, Haidar Muhsen Al-Khazali, Cédric Gollion, Basit Ali Chaudhry, Messoud Ashina, Håkan Ashina

Do headaches impact pregnancy planning behaviors? A cross-sectional school-based study in Japan

Masahito Katsuki, Yasuhiko Matsumori, Muneto Tatsumoto, Keisuke Suzuki, Daiki Sato, Koki Kikugawa, Shigeharu Kamado, Siobhán O’Connor, Kieran Moran

Mechanistic intersections between migraine and major depressive disorder

Micah Johnson, Yassine Filali, Anjayooluwa Adegboyo, Maureen Eberle, Abigail Townsend, Yamam Hussien, Catherine Marcinkiewcz, Rainbo Hultman

Spi1 aggravates neuropathic pain by modulating Clec7a-mediated neuroinflammation and microglial phagocytosis

Yin Xu, Xinli Liu, Hui Chen, Yun Zhao, Yubai Zhao, Yu Xie, Jiahui Pang, Hui Zeng, Yanyan Zeng, Weiwei Peng, Manxu Zheng, Wen Wu

Jun 25
Issue: Special Issue 2/2025
Abstracts from the 18th European Headache Congress (EHC)

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