Skip to main content
Top
Published in:

Open Access 01-12-2017 | Short report

The incidence of MRSA infections in the United States: is a more comprehensive tracking system needed?

Authors: Kevin T. Kavanagh, Said Abusalem, Lindsay E. Calderon

Published in: Antimicrobial Resistance & Infection Control | Issue 1/2017

Login to get access

Abstract

A review of epidemiological studies on the incidence of MRSA infections overtime was performed along with an analysis of data available for download from Hospital Compare (https://​data.​medicare.​gov/​data/​hospital-compare). We found the estimations of the incidence of MRSA infections varied widely depending upon the type of population studied, the types of infections captured and in the definitions and terminology used to describe the results. We could not find definitive evidence that the incidence of MRSA infections in U.S. community or facilities is decreasing significantly. Of concern are recent data reported to the National Healthcare Safety Network (NHSN) on MRSA bloodstream infections which indicate that by the end of 2015 there had been little change in the average facility Standardized Infection Ratio (0.988), compared to a 2010–2011 baseline and is significantly increased compared to the previous year. This is in contradistinction to the recent Veterans Administration study which reported over an 80% reduction in MRSA infections. However, this discrepancy may be due to the inability to reconcile the baselines of the two data sets; and the observed increase may be artifactual due to aberrations in the NHSN tracking system. Our review supports the need for implementation of a comprehensive tracking and monitoring system involving all types of healthcare facilities for multi-drug resistant organisms, along with concomitant funding for both staff and infrastructure. Without such a system, determining the effectiveness of interventions such as antibiotic stewardship and chlorhexidine bathing will be hindered.
Literature
2.
go back to reference Klevens RM, Morrison MA, Nadle J, Petit S, Gershman K, Ray S, Harrison LH, Lynfield R, Dumyati G, Townes JM, Craig AS, Zell ER, Fosheim GE, McDougal LK, Carey RB, Fridkin SK. Active bacterial core surveillance (ABCs) MRSA investigators. Invasive methicillin-resistant staphylococcus aureus infections in the United States. JAMA. 2007;298(15):1763–71.CrossRefPubMed Klevens RM, Morrison MA, Nadle J, Petit S, Gershman K, Ray S, Harrison LH, Lynfield R, Dumyati G, Townes JM, Craig AS, Zell ER, Fosheim GE, McDougal LK, Carey RB, Fridkin SK. Active bacterial core surveillance (ABCs) MRSA investigators. Invasive methicillin-resistant staphylococcus aureus infections in the United States. JAMA. 2007;298(15):1763–71.CrossRefPubMed
3.
go back to reference Kallen AJ, Mu Y, Bulens S, Reingold A, Petit S, Gershman K, Ray SM, Harrison LH, Lynfield R, Dumyati G, Townes JM, Schaffner W, Patel PR, Fridkin SK. Active bacterial core surveillance (ABCs) MRSA investigators of the emerging infections program. Health care-associated invasive MRSA infections, 2005-2008. JAMA. 2010;304(6):641–8. doi:10.1001/jama.2010.1115.CrossRefPubMed Kallen AJ, Mu Y, Bulens S, Reingold A, Petit S, Gershman K, Ray SM, Harrison LH, Lynfield R, Dumyati G, Townes JM, Schaffner W, Patel PR, Fridkin SK. Active bacterial core surveillance (ABCs) MRSA investigators of the emerging infections program. Health care-associated invasive MRSA infections, 2005-2008. JAMA. 2010;304(6):641–8. doi:10.​1001/​jama.​2010.​1115.CrossRefPubMed
4.
go back to reference Dantes R, Mu Y, Belflower R, Aragon D, Dumyati G, Harrison LH, Lessa FC, Lynfield R, Nadle J, Petit S, Ray SM, Schaffner W, Townes J, Fridkin S. Emerging infections program–active bacterial core surveillance MRSA surveillance investigators. National burden of invasive methicillin-resistant Staphylococcus aureus infections, United States, 2011. JAMA Intern Med. 2013;173(21):1970–8. doi:10.1001/jamainternmed.2013.10423.PubMed Dantes R, Mu Y, Belflower R, Aragon D, Dumyati G, Harrison LH, Lessa FC, Lynfield R, Nadle J, Petit S, Ray SM, Schaffner W, Townes J, Fridkin S. Emerging infections program–active bacterial core surveillance MRSA surveillance investigators. National burden of invasive methicillin-resistant Staphylococcus aureus infections, United States, 2011. JAMA Intern Med. 2013;173(21):1970–8. doi:10.​1001/​jamainternmed.​2013.​10423.PubMed
5.
go back to reference Iwamoto M, Mu Y, Lynfield R, Bulens SN, Nadle J, Aragon D, Petit S, Ray SM, Harrison LH, Dumyati G, Townes JM, Schaffner W, Gorwitz RJ, Lessa FC. Trends in invasive methicillin-resistant Staphylococcus aureus infections. Pediatrics. 2013;132(4):e817–24. doi:10.1542/peds.2013-1112. Epub 2013 Sep 23.CrossRefPubMed Iwamoto M, Mu Y, Lynfield R, Bulens SN, Nadle J, Aragon D, Petit S, Ray SM, Harrison LH, Dumyati G, Townes JM, Schaffner W, Gorwitz RJ, Lessa FC. Trends in invasive methicillin-resistant Staphylococcus aureus infections. Pediatrics. 2013;132(4):e817–24. doi:10.​1542/​peds.​2013-1112. Epub 2013 Sep 23.CrossRefPubMed
6.
go back to reference Klein EY, Sun L, Smith DL, Laxminarayan R. The changing epidemiology of methicillin-resistant Staphylococcus aureus in the United States: a national observational study. Am J Epidemiol. 2013;177(7):666–74. doi:10.1093/aje/kws273. Epub 2013 Feb 28.CrossRefPubMed Klein EY, Sun L, Smith DL, Laxminarayan R. The changing epidemiology of methicillin-resistant Staphylococcus aureus in the United States: a national observational study. Am J Epidemiol. 2013;177(7):666–74. doi:10.​1093/​aje/​kws273. Epub 2013 Feb 28.CrossRefPubMed
7.
go back to reference David MZ, Medvedev S, Hohmann SF, Ewigman B, Daum RS. Increasing burden of methicillin-resistant Staphylococcus aureus hospitalizations at US academic medical centers, 2003-2008. Infect Control Hosp Epidemiol. 2012;33(8):782–9. doi:10.1086/666640. Epub 2012 Jun 11.CrossRefPubMedPubMedCentral David MZ, Medvedev S, Hohmann SF, Ewigman B, Daum RS. Increasing burden of methicillin-resistant Staphylococcus aureus hospitalizations at US academic medical centers, 2003-2008. Infect Control Hosp Epidemiol. 2012;33(8):782–9. doi:10.​1086/​666640. Epub 2012 Jun 11.CrossRefPubMedPubMedCentral
9.
go back to reference Kavanagh KT. Multi-Drug Resistant Organisms - Reporting and Health Dept. Engagement. Kentucky Joint House and Senate Health and Welfare Committee Meeting. 2016. Kavanagh KT. Multi-Drug Resistant Organisms - Reporting and Health Dept. Engagement. Kentucky Joint House and Senate Health and Welfare Committee Meeting. 2016.
11.
go back to reference Landrum ML, Neumann C, Cook C, Chukwuma U, Ellis MW, Hospenthal DR, Murray CK. Infectious disease service, San Antonio Military Medical Center, Fort Sam Houston, Texas 78234, Epidemiology of Staphylococcus aureus blood and skin and soft tissue infections in the US military health system, 2005-2010. JAMA. 2012;308(1):50–9.CrossRefPubMed Landrum ML, Neumann C, Cook C, Chukwuma U, Ellis MW, Hospenthal DR, Murray CK. Infectious disease service, San Antonio Military Medical Center, Fort Sam Houston, Texas 78234, Epidemiology of Staphylococcus aureus blood and skin and soft tissue infections in the US military health system, 2005-2010. JAMA. 2012;308(1):50–9.CrossRefPubMed
12.
go back to reference Evans ME, Kralovic SM, Simbartl LA, Jain R, Roselle GA. Eight years of decreased methicillin-resistant staphylococcus aureus health care-associated infections associated with a Veterans affairs prevention initiative. Am J Infect Control. 2017;45(1):13–6. doi:10.1016/j.ajic.2016.08.010.CrossRefPubMed Evans ME, Kralovic SM, Simbartl LA, Jain R, Roselle GA. Eight years of decreased methicillin-resistant staphylococcus aureus health care-associated infections associated with a Veterans affairs prevention initiative. Am J Infect Control. 2017;45(1):13–6. doi:10.​1016/​j.​ajic.​2016.​08.​010.CrossRefPubMed
13.
go back to reference Huang SS, Septimus E, Kleinman K, Moody J, Hickok J, Avery TR, Lankiewicz J, Gombosev A, Terpstra L, Hartford F, Hayden MK, Jernigan JA, Weinstein RA, Fraser VJ, Haffenreffer K, Cui E, Kaganov RE, Lolans K, Perlin JB, Platt R; the CDC Prevention Epicenters Program; the AHRQ DECIDE Network and Healthcare-Associated Infections Program. Targeted versus Universal Decolonization to Prevent ICU Infection. N Engl J Med. 2013 May 29. [Epub ahead of print] Retrieved on Mar. 30, 2017 from: http://www.ncbi.nlm.nih.gov/pubmed/23718152. Huang SS, Septimus E, Kleinman K, Moody J, Hickok J, Avery TR, Lankiewicz J, Gombosev A, Terpstra L, Hartford F, Hayden MK, Jernigan JA, Weinstein RA, Fraser VJ, Haffenreffer K, Cui E, Kaganov RE, Lolans K, Perlin JB, Platt R; the CDC Prevention Epicenters Program; the AHRQ DECIDE Network and Healthcare-Associated Infections Program. Targeted versus Universal Decolonization to Prevent ICU Infection. N Engl J Med. 2013 May 29. [Epub ahead of print] Retrieved on Mar. 30, 2017 from: http://​www.​ncbi.​nlm.​nih.​gov/​pubmed/​23718152.
Metadata
Title
The incidence of MRSA infections in the United States: is a more comprehensive tracking system needed?
Authors
Kevin T. Kavanagh
Said Abusalem
Lindsay E. Calderon
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Antimicrobial Resistance & Infection Control / Issue 1/2017
Electronic ISSN: 2047-2994
DOI
https://doi.org/10.1186/s13756-017-0193-0

Keynote webinar | Spotlight on menopause

Menopause can have a significant impact on the body, with effects ranging beyond the endocrine and reproductive systems. Learn about the broader systemic effects of menopause, so you can help patients in your clinics through the transition.   

Prof. Martha Hickey
Dr. Claudia Barth
Dr. Samar El Khoudary
Developed by: Springer Medicine
Watch now

Keynote webinar | Spotlight on adolescent vaping

  • Live
  • Webinar | 29-01-2025 | 18:00 (CET)

Growing numbers of young people are using e-cigarettes, despite warnings of respiratory effects and addiction. How can doctors tackle the epidemic, and what health effects should you prepare to manage in your clinics?

Watch it live: Wednesday 29th January, 18:00-19:30 CET
 

Prof. Ann McNeill
Dr. Debbie Robson
Benji Horwell
Developed by: Springer Medicine
Join the webinar

Keynote webinar | Spotlight on modern management of frailty

Frailty has a significant impact on health and wellbeing, especially in older adults. Our experts explain the factors that contribute to the development of frailty and how you can manage the condition and reduce the risk of disability, dependency, and mortality in your patients.

Prof. Alfonso Cruz-Jentoft
Prof. Barbara C. van Munster
Prof. Mirko Petrovic
Developed by: Springer Medicine
Watch now

A quick guide to ECGs

Improve your ECG interpretation skills with this comprehensive, rapid, interactive course. Expert advice provides detailed feedback as you work through 50 ECGs covering the most common cardiac presentations to ensure your practice stays up to date. 

PD Dr. Carsten W. Israel
Developed by: Springer Medizin
Start the cases

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine
Read more