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Journal of Diabetes & Metabolic Disorders
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Open Access 01-12-2017 | Research article

The effect of cardamom supplementation on serum lipids, glycemic indices and blood pressure in overweight and obese pre-diabetic women: a randomized controlled trial

Authors: Yaghooblou Fatemeh, Fereydoun Siassi, Abbas Rahimi, Fariba Koohdani, Farideh Doostan, Mostafa Qorbani, Gity Sotoudeh

Published in: Journal of Diabetes & Metabolic Disorders | Issue 1/2017

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Abstract

Background

Spice consumption helps the treatment of diseases due to their antioxidant and anti-inflammatory contents. Cardamom is one of this spices; therefore, this study is designed to determine the effect of cardamom supplementation on serum lipids, glycemic indices, and blood pressure in pre-diabetic women.

Methods

Eighty overweight or obese pre-diabetic women were randomly allocated to two groups. The intervention group received 3 g of green cardamom and the placebo group received 3 g of rusk powder for 2 months. The physical activity level, dietary intake, anthropometric measurements, Blood pressure, fasting blood sugar (FBS), triglyceride (TG), total cholesterol (TC), low density lipoprotein (LDL-C), high density lipoprotein (HDL-C), insulin, body mass index (BMI), insulin resistance, and insulin sensitivity were measured before and after intervention.

Results

After intervention, mean TC (p = 0.02) and LDL-C (p = 0.01) significantly decreased and insulin sensitivity (p = 0.03) increased in the cardamom group. In the control group, mean HDL-C (p = 0.02) significantly decreased after the study. We observed no significant decrease in systolic and diastolic blood pressure, glycemic indices, and serum lipids values in the cardamom group compared to the placebo group.

Conclusions

Green cardamom supplementation may have a protective effect on HDL-C level in pre-diabetic subjects. It improves some blood parameters in these subjects; however, its effects are not different from placebo.

Trial registration

Iranian Registry of Clinical Trials, IRCT201406081725​4N2. Registered 2 September 2014.
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Metadata
Title
The effect of cardamom supplementation on serum lipids, glycemic indices and blood pressure in overweight and obese pre-diabetic women: a randomized controlled trial
Authors
Yaghooblou Fatemeh
Fereydoun Siassi
Abbas Rahimi
Fariba Koohdani
Farideh Doostan
Mostafa Qorbani
Gity Sotoudeh
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Journal of Diabetes & Metabolic Disorders / Issue 1/2017
Electronic ISSN: 2251-6581
DOI
https://doi.org/10.1186/s40200-017-0320-8

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