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20-11-2023 | Testosterone | Original Article

The effect of testosterone level on metabolic syndrome: a cross-sectional study

Authors: Sercan Gucenmez, Pinar Yildiz, Omer Donderici, Rustu Serter

Published in: Hormones

Abstract

Background

Metabolic syndrome (MS) may reduce circulating testosterone and, at the same time, low testosterone levels may lead to MS. Thus, identifying problems regarding sex hormones and examining their effects on the pathogenesis of MS is important to prevent serious complications of the condition, such as diabetes or cardiovascular diseases.

Aims

This study aimed to investigate the correlations between MS-related parameters and androgen levels.

Methods

A total of 108 males [median age 48.5 years (min/max = 21/77 years)] were included in the study. Blood pressure and anthropometric measurements (body mass index, waist circumference, hip circumference, thigh circumference, neck circumference, and length of index and ring finger) were performed. Biochemical analysis was assessed. Additionally, total testosterone, free testosterone, and sex hormone binding globulin levels were investigated.

Results

Weak negative correlations were observed between testosterone levels and several anthropometric measures/glucose metabolisms (p < 0.05). The highest correlation was between total testosterone levels and body mass index (rho= −0.390, p < 0.001)

Conclusion

According to our results, controlling weight, one of the preventable risk factors, can have a positive effect on testosterone levels and, therefore, on the cardiovascular system through different mechanisms.

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Title: The effect of testosterone level on metabolic syndrome: a cross-sectional study
Authors: Sercan Gucenmez
Pinar Yildiz
Omer Donderici
Rustu Serter
Publication date: 20-11-2023
Publisher: Springer International Publishing
Keywords: Testosterone
Androgens
Insulins
Insulins
Published in: Hormones
Print ISSN: 1109-3099
Electronic ISSN: 2520-8721
DOI: https://doi.org/10.1007/s42000-023-00507-w

Webinar | 08-11-2023 | 18:00 (CET)

Keynote Webinar | Spotlight on Diet and Diabetes

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An expert-led symposium exploring the prevention and management of type 2 diabetes through dietary interventions. Highlights include discussion of the recent EASD guidelines, therapeutic diets, food types and processing, plus psychological factors that influence patient success, and the drivers of healthy eating and diabetes control.

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Keynote Webinar | Spotlight on Diet and Diabetes

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Abstract

Background

Aims

Methods

Results

Conclusion

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Keynote Webinar | Spotlight on Diet and Diabetes