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Current Addiction Reports

22-09-2023

Sex and Gender Differences in Co-Occurring Alcohol Use Disorder and PTSD

Authors: Tanya C. Saraiya, Sudie E. Back, Amber M. Jarnecke, Shannon M. Blakey, Alexandria G. Bauer, Delisa G. Brown, Lesia M. Ruglass, Therese Killeen, Denise A. Hien

Published in: Current Addiction Reports

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Abstract

Purpose of Review

Research demonstrates a strong association between alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD). However, less is known about sex- and gender-based differences among individuals with AUD + PTSD. This narrative review examines recent literature in this area and aims to be a reference for future research endeavors.

Recent Findings

Extant literature shows that intertwining biological systems increase females’ risk of developing PTSD and experiencing more adverse effects from AUD compared to males. Sex-based physiological differences further interact with gendered sociocultural environments to influence the risk of AUD + PTSD. Emerging research suggests potential gender-specific pathways between PTSD, coping, and AUD which may inform prevention and treatment. However, barriers to care are often gender-specific and tailored approaches are needed to improve reach and uptake.

Summary

Additional research is needed to examine intersectional and contextual factors that synergistically influence sex/gender differences in AUD + PTSD, particularly beyond cisgender identities, and mechanisms of action.
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Metadata
Title
Sex and Gender Differences in Co-Occurring Alcohol Use Disorder and PTSD
Authors
Tanya C. Saraiya
Sudie E. Back
Amber M. Jarnecke
Shannon M. Blakey
Alexandria G. Bauer
Delisa G. Brown
Lesia M. Ruglass
Therese Killeen
Denise A. Hien
Publication date
22-09-2023
Publisher
Springer International Publishing
Published in
Current Addiction Reports
Electronic ISSN: 2196-2952
DOI
https://doi.org/10.1007/s40429-023-00511-5