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16-01-2024 | Sarcopenia | Original Article

Percent vital capacity predicts postoperative sarcopenia after esophagectomy in initially nonsarcopenic esophageal cancer patients: a retrospective cohort study

Authors: Shinichiro Shiomi, Yasuhiro Okumura, Kosuke Nakane, Tetsuro Toriumi, Koichiro Kawasaki, Shoh Yajima, Koichi Yagi, Sachiyo Nomura, Yasuyuki Seto

Published in: Surgery Today | Issue 7/2024

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Abstract

Purpose

The development of sarcopenia after esophagectomy is reported to affect the outcomes of patients with esophageal cancer (EC); however, the characteristics of patients likely to be predisposed to postoperative sarcopenia have not been defined. This study explores the associations between preoperative respiratory function and surgery-induced sarcopenia in EC patients confirmed as nonsarcopenic preoperatively.

Methods

The subjects of this retrospective review were 128 nonsarcopenic patients who underwent esophagectomy for EC. We took body composition measurements and performed physical function tests 3 and 6 months postoperatively, to establish whether sarcopenia was present, according to the 2019 Asian Working Group for Sarcopenia guideline. We defined patients with surgery-induced sarcopenia as those with evidence of the development of sarcopenia within 6 months postoperatively or those with documented sarcopenia at 3 months but who could not be evaluated at 6 months.

Results

Surgery-induced sarcopenia developed in 19 of the 128 patients (14.8%), which correlated significantly with the preoperative %VC value (p < 0.01), but not with the preoperative FEV1.0% value. We set the lower quartile %VC value (91%) as the cut-off for predicting surgery-induced sarcopenia. A low %VC was independently associated with surgery-induced sarcopenia (odds ratio: 5.74; 95% confidence interval: 1.99–16.57; p < 0.01).

Conclusions

Based on the findings of this study, %VC was a simple but valuable factor for predicting sarcopenia induced by esophagectomy.
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Metadata
Title
Percent vital capacity predicts postoperative sarcopenia after esophagectomy in initially nonsarcopenic esophageal cancer patients: a retrospective cohort study
Authors
Shinichiro Shiomi
Yasuhiro Okumura
Kosuke Nakane
Tetsuro Toriumi
Koichiro Kawasaki
Shoh Yajima
Koichi Yagi
Sachiyo Nomura
Yasuyuki Seto
Publication date
16-01-2024
Publisher
Springer Nature Singapore
Published in
Surgery Today / Issue 7/2024
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-023-02788-5

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