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Open Access 18-12-2024 | Sarcoma | Review

Soft tissue tumor imaging in adults: European Society of Musculoskeletal Radiology–Guidelines 2024: imaging immediately after neoadjuvant therapy in soft tissue sarcoma, soft tissue tumor surveillance, and the role of interventional radiology

Authors: Iris-Melanie Noebauer-Huhmann, Joan C. Vilanova, Olympia Papakonstantinou, Marc-André Weber, Radhesh K. Lalam, Violeta Vasilevska Nikodinovska, Hatice T. Sanal, Frédéric E. Lecouvet, Ana Navas, José Martel-Villagrán, Jacky W. J. de Rooy, Jan Fritz, Koenraad Verstraete, Thomas Grieser, Pavol Szomolanyi, Snehansh Chaudhary, Luca Maria Sconfienza, Alberto S. Tagliafico, P. Diana Afonso, Omar M. Albtoush, Giacomo Aringhieri, Remide Arkun, Gunnar Aström, Alberto Bazzocchi, Rajesh Botchu, Martin Breitenseher, Danoob Dalili, Mark Davies, Milko C. de Jonge, Berna D. Mete, Jan L. M. A. Gielen, Geoff Hide, Amanda Isaac, Slavcho Ivanoski, Ramy M. Mansour, Catherine Mccarthy, Lorenzo Muntaner-Gimbernat, Paul O’Donnell, Şebnem Örgüç, Winston J. Rennie, Santiago Resano, Philip Robinson, Simone A. J. Ter Horst, Kirsten van Langevelde, Klaus Wörtler, Marita Koelz, Joannis Panotopoulos, Reinhard Windhager, Barbara J. Fueger, Maximilian Schmid, Filip M. Vanhoenacker

Published in: European Radiology

Abstract

Objectives

An update of the first European Society of Musculoskeletal Radiology (ESSR) consensus on soft tissue tumor imaging in 2015 became necessary due to technical advancements, further insights into specific entities, and the revised WHO classification (2020) and AJCC staging system (2017). The third part of the revised guidelines covers algorithms and techniques beyond initial imaging: (1) Imaging after neoadjuvant therapy in soft tissue sarcoma, (2) sarcoma surveillance, and (3) special aspects, including surveillance of non-malignant entities and the role of interventional radiology.

Materials and methods

A validated Delphi method based on peer-reviewed literature was used to derive consensus among a panel of 46 specialized musculoskeletal radiologists from 12 European countries. Statements that had undergone interdisciplinary revision were scored online by level of agreement (0 to 10) during two iterative rounds that could result in either ‘group consensus,’ ‘group agreement,’ or ‘lack of agreement.’

Results

The three sections contain 47 statements with comments. Group consensus was reached in 91.5%, group agreement in 6.4%, lack of agreement in 2.1%. In sarcoma, imaging immediately after neoadjuvant therapy is pivotal for determining the therapy effects and for resection-planning; surveillance should include imaging at fixed grade- and type-dependent intervals. In general, MRI is the method of choice for loco-regional surveillance of soft tissue sarcomas, and chest CT to assess metastatic disease. Interventional radiology has a role, especially in oligometastatic disease, palliative tumor control and local recurrences.

Conclusion

Strategies for standardized soft tissue tumor imaging regarding therapy control, surveillance, and useful interventional procedures are provided.

Key Points

Question An ESSR consensus update on soft tissue tumor imaging regarding surveillance became necessary due to technical advancements, further entity-specific insights, and revised WHO- and AJCC-classifications.

Findings Imaging immediately after neoadjuvant therapy in soft tissue sarcoma is pivotal. Post-therapeutic surveillance should include imaging at regular intervals, stratified for tumor grade and type.

Clinical relevance The updated ESSR soft tissue tumor imaging guidelines aim to provide best practice expert consensus for standardized imaging, to support radiologists in their decision-making, and to improve examination comparability, both in individual patients and in future studies on individualized strategies.

Available only for authorised users

Noebauer-Huhmann IM, Weber MA, Lalam RK et al (2015) Soft tissue tumors in adults: ESSR-approved guidelines for diagnostic imaging. Semin Musculoskelet Radiol 19:475–482. https://doi.org/10.1055/s-0035-1569251CrossRefPubMed

WHO (2020) WHO classification of tumours of soft tissue and bone, 5th edn. Available via https://publications.iarc.fr/Book-And-Report-Series/Who-Classification-Of-Tumours/Soft-Tissue-And-Bone-Tumours-2020. Accessed 14 Jun 2023

Amin MB, Greene FL, Edge SB et al (2017) The eighth edition AJCC cancer staging manual: continuing to build a bridge from a population-based to a more “personalized” approach to cancer staging. CA Cancer J Clin 67:93–99. https://doi.org/10.3322/caac.21388CrossRefPubMed

Euro Health Observatory (2023) Improving healthcare quality in Europe: chapter 9: clinical practice guidelines as a quality strategy. 233–263. Available from https://iris.who.int/bitstream/handle/10665/327356/9789289051750-eng.pdf?sequence=1. Accessed 14 Jun 2023

Khodyakov D (2023) Generating evidence using the Delphi method. Available from https://i2insights.org/2023/10/17/delphi-method/. Accessed 17 Oct 2023

Taylor E (2020) We agree, don’t we? The Delphi method for health environments research. HERD 13:11–23. https://doi.org/10.1177/1937586719887709CrossRefPubMed

Mascarenhas VV, Castro MO, Rego PA et al (2020) The Lisbon Agreement on Femoroacetabular Impingement Imaging—part 1: overview. Eur Radiol 30:5281–5297. https://doi.org/10.1007/s00330-020-06822-9CrossRefPubMed

Noebauer-Huhmann IM, Vanhoenacker FM, Vilanova JC et al (2023) Soft tissue tumor imaging in adults: European Society of Musculoskeletal Radiology-Guidelines 2023—overview, and primary local imaging: how and where? Eur Radiol. https://doi.org/10.1007/s00330-023-10425-5

Noebauer-Huhmann IM, Vanhoenacker FM, Vilanova JC et al (2024) Soft tissue tumor imaging in adults: whole-body staging in sarcoma, non-malignant entities requiring special algorithms, pitfalls and special imaging aspects. Guidelines 2024 from the European Society of Musculoskeletal Radiology (ESSR). Eur Radiol. https://doi.org/10.1007/s00330-024-10897-z

10.

Brennan MF, Antonescu CR, Moraco N, Singer S (2014) Lessons learned from the study of 10,000 patients with soft tissue sarcoma. Ann Surg 260:416–421. https://doi.org/10.1097/SLA.0000000000000869CrossRefPubMed

11.

Google Forms. Available via https://www.google.com/forms. Accessed 14 Jun 2023

12.

WHO (2014) Chapter 16: decision-making for guideline development at WHO. In: WHO handbook for guideline development, 2nd edn. World Health Organization. Available from https://www.who.int/publications/i/item/9789241548960

13.

European Society of Musculoskeletal Radiology (ESSR) Subcommittee Tumours (2023) EUROPEAN FORUM FOR EDUCATION AND RESEARCH OF MUSCULOSKELETAL RADIOLOGY. Available from https://www.essr.org/subcommittees/tumours/. Accessed 14 Jun 2023

14.

Kalisvaart GM, Bloem JL, Bovee J et al (2021) Personalising sarcoma care using quantitative multimodality imaging for response assessment. Clin Radiol 76:313.e1–313.e13. https://doi.org/10.1016/j.crad.2020.12.009CrossRefPubMed

15.

Soldatos T, Ahlawat S, Montgomery E, Chalian M, Jacobs MA, Fayad LM (2016) Multiparametric assessment of treatment response in high-grade soft-tissue sarcomas with anatomic and functional MR imaging sequences. Radiology 278:831–840. https://doi.org/10.1148/radiol.2015142463CrossRefPubMed

16.

Messiou C, Bonvalot S, Gronchi A et al (2016) Evaluation of response after pre-operative radiotherapy in soft tissue sarcomas; the European Organisation for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) and Imaging Group recommendations for radiological examination and reporting with an emphasis on magnetic resonance imaging. Eur J Cancer 56:37–44. https://doi.org/10.1016/j.ejca.2015.12.008CrossRefPubMed

17.

Sawamura C, Matsumoto S, Shimoji T, Okawa A, Ae K (2014) How long should we follow patients with soft tissue sarcomas? Clin Orthop Relat Res 472:842–848. https://doi.org/10.1007/s11999-013-3076-6CrossRefPubMed

18.

Italiano A, Le Cesne A, Mendiboure J et al (2014) Prognostic factors and impact of adjuvant treatments on local and metastatic relapse of soft-tissue sarcoma patients in the competing risks setting. Cancer 120:3361–3369. https://doi.org/10.1002/cncr.28885CrossRefPubMed

19.

Sekimizu M, Ogura K, Yasunaga H et al (2019) Development of nomograms for prognostication of patients with primary soft tissue sarcomas of the trunk and extremity: report from the Bone and Soft Tissue Tumor Registry in Japan. BMC Cancer 19:657. https://doi.org/10.1186/s12885-019-5875-yCrossRefPubMedPubMedCentral

20.

Grobmyer SR, Brennan MF (2003) Predictive variables detailing the recurrence rate of soft tissue sarcomas. Curr Opin Oncol 15:319–326. https://doi.org/10.1097/00001622-200307000-00007CrossRefPubMed

21.

Smolle MA, Sande MV, Callegaro D et al (2019) Individualizing follow-up strategies in high-grade soft tissue sarcoma with flexible parametric competing risk regression models. Cancers (Basel) https://doi.org/10.3390/cancers12010047

22.

Zagars GK, Ballo MT, Pisters PW, Pollock RE, Patel SR, Benjamin RS (2003) Prognostic factors for disease-specific survival after first relapse of soft-tissue sarcoma: analysis of 402 patients with disease relapse after initial conservative surgery and radiotherapy. Int J Radiat Oncol Biol Phys 57:739–747. https://doi.org/10.1016/s0360-3016(03)00714-4CrossRefPubMed

23.

Toulmonde M, Le Cesne A, Mendiboure J et al (2014) Long-term recurrence of soft tissue sarcomas: prognostic factors and implications for prolonged follow-up. Cancer 120:3003–3006. https://doi.org/10.1002/cncr.28836CrossRefPubMed

24.

Watts AC, Teoh K, Evans T, Beggs I, Robb J, Porter D (2008) MRI surveillance after resection for primary musculoskeletal sarcoma. J Bone Joint Surg Br 90:484–487. https://doi.org/10.1302/0301-620X.90B4.20089CrossRefPubMed

25.

Grimer R, Judson I, Peake D, Seddon B (2010) Guidelines for the management of soft tissue sarcomas. Sarcoma 2010:506182. https://doi.org/10.1155/2010/506182CrossRefPubMedPubMedCentral

26.

Gibbs JF, Lee RJ, Driscoll DL, McGrath BE, Mindell ER, Kraybill WG (2000) Clinical importance of late recurrence in soft-tissue sarcomas. J Surg Oncol 73:81–86. https://doi.org/10.1002/(SICI)1096-9098(200002)73:23.0.CO;2-9CrossRefPubMed

27.

De Angelis F, Guy F, Bertaut A et al (2019) Limbs and trunk soft tissue sarcoma systematic local and remote monitoring by MRI and thoraco-abdomino-pelvic scanner: a single-centre retrospective study. Eur J Surg Oncol 45:1274–1280. https://doi.org/10.1016/j.ejso.2019.02.002CrossRefPubMed

28.

Tan MC, Brennan MF, Kuk D et al (2016) Histology-based classification predicts pattern of recurrence and improves risk stratification in primary retroperitoneal sarcoma. Ann Surg 263:593–600. https://doi.org/10.1097/SLA.0000000000001149CrossRefPubMed

29.

Liebl LS, Elson F, Quaas A, Gawad KA, Izbicki JR (2007) Value of repeat resection for survival in pulmonary metastases from soft tissue sarcoma. Anticancer Res 27:2897–2902PubMed

30.

Hovgaard TB, Nymark T, Skov O, Petersen MM (2017) Follow-up after initial surgical treatment of soft tissue sarcomas in the extremities and trunk wall. Acta Oncol 56:1004–1012. https://doi.org/10.1080/0284186X.2017.1299937CrossRefPubMed

31.

Park JW, Yoo HJ, Kim HS et al (2019) MRI surveillance for local recurrence in extremity soft tissue sarcoma. Eur J Surg Oncol 45:268–274. https://doi.org/10.1016/j.ejso.2018.08.032CrossRefPubMed

32.

England P, Hong Z, Rhea L, Hirbe A, McDonald D, Cipriano C (2020) Does advanced imaging have a role in detecting local recurrence of soft-tissue sarcoma? Clin Orthop Relat Res 478:2812–2820. https://doi.org/10.1097/CORR.0000000000001351CrossRefPubMedPubMedCentral

33.

Koenig FRM, Kielburg AH, Chaudhary SR et al (2024) Beyond clinical examination: utilizing MRI surveillance to detect recurrence of soft tissue sarcomas and differentiate from posttherapeutic changes. Biomedicines. https://doi.org/10.3390/biomedicines12081640

34.

George A, Grimer RJ, James SLJ (2018) Could routine magnetic resonance imaging detect local recurrence of musculoskeletal sarcomas earlier? A cost-effectiveness study. Indian J Orthop 52:81–86. https://doi.org/10.4103/ortho.IJOrtho_234_17CrossRefPubMedPubMedCentral

35.

Cheney MD, Giraud C, Goldberg SI et al (2014) MRI surveillance following treatment of extremity soft tissue sarcoma. J Surg Oncol 109:593–596. https://doi.org/10.1002/jso.23541CrossRefPubMed

36.

Labarre D, Aziza R, Filleron T et al (2009) Detection of local recurrences of limb soft tissue sarcomas: is magnetic resonance imaging (MRI) relevant? Eur J Radiol 72:50–53. https://doi.org/10.1016/j.ejrad.2009.05.027CrossRefPubMed

37.

Verstraete KL, Lang P (2000) Bone and soft tissue tumors: the role of contrast agents for MR imaging. Eur J Radiol 34:229–246. https://doi.org/10.1016/s0720-048x(00)00202-3CrossRefPubMed

38.

Dammerer D, Van Beeck A, Schneeweiss V, Schwabegger A (2020) Follow-up strategies for primary extremity soft-tissue sarcoma in adults: a systematic review of the published literature. In Vivo 34:3057–3068. https://doi.org/10.21873/invivo.12140CrossRefPubMedPubMedCentral

39.

Sedaghat S, Sedaghat M, Meschede J, Jansen O, Both M (2021) Diagnostic value of MRI for detecting recurrent soft-tissue sarcoma in a long-term analysis at a multidisciplinary sarcoma center. BMC Cancer 21:398. https://doi.org/10.1186/s12885-021-08113-yCrossRefPubMedPubMedCentral

40.

Ackman JB, Chung JH, Walker CM et al (2021) ACR Appropriateness Criteria® imaging of mediastinal masses. J Am Coll Radiol 18:S37–S51. https://doi.org/10.1016/j.jacr.2021.01.007CrossRefPubMed

41.

Alvarez Alvarez R, Manzano A, Agra Pujol C et al (2023) Updated review and clinical recommendations for the diagnosis and treatment of patients with retroperitoneal sarcoma by the Spanish Sarcoma Research Group (GEIS). Cancers (Basel) https://doi.org/10.3390/cancers15123194

42.

Follmann M (2024) German Guideline Program in Oncology (German Cancer Society, German Cancer Aid, AWMF): soft tissue sarcoma long version 1.1, 2022, AWMF registration number: 032/044OL. Available from https://www.leitlinienprogrammonkologie.de/leitlinien/adulteweichgewebesarkome/

43.

Tagliafico A, Truini M, Spina B et al (2015) Follow-up of recurrences of limb soft tissue sarcomas in patients with localized disease: performance of ultrasound. Eur Radiol 25:2764–2770. https://doi.org/10.1007/s00330-015-3645-zCrossRefPubMed

44.

Singer AD, Wong P, Umpierrez M et al (2020) The accuracy of a novel sonographic scanning and reporting protocol to survey for soft tissue sarcoma local recurrence. Skeletal Radiol 49:2039–2049. https://doi.org/10.1007/s00256-020-03520-xCrossRefPubMed

45.

Gielen J, Vanhoenacker F, Ceulemans R et al (2017) Ultrasound and color Doppler ultrasound of soft tissue tumors and tumorlike lesions. In: Imaging of soft tissue tumors. Springer, Cham, p 3–40

46.

Park SY, Chung HW, Chae SY, Lee JS (2016) Comparison of MRI and PET-CT in detecting the loco-regional recurrence of soft tissue sarcomas during surveillance. Skeletal Radiol 45:1375–1384. https://doi.org/10.1007/s00256-016-2440-5CrossRefPubMed

47.

Susa M, Oguro S, Kikuta K et al (2015) Novel MR imaging method–MAVRIC–for metal artifact suppression after joint replacement in musculoskeletal tumor patients. BMC Musculoskelet Disord 16:377. https://doi.org/10.1186/s12891-015-0838-1CrossRefPubMedPubMedCentral

48.

Jungmann PM, Agten CA, Pfirrmann CW, Sutter R (2017) Advances in MRI around metal. J Magn Reson Imaging 46:972–991. https://doi.org/10.1002/jmri.25708CrossRefPubMed

49.

Dangoor A, Seddon B, Gerrand C, Grimer R, Whelan J, Judson I (2016) UK guidelines for the management of soft tissue sarcomas. Clin Sarcoma Res 6:20. https://doi.org/10.1186/s13569-016-0060-4CrossRefPubMedPubMedCentral

50.

Gronchi A, Miah AB, Dei Tos AP et al (2021) Soft tissue and visceral sarcomas: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 32:1348–1365. https://doi.org/10.1016/j.annonc.2021.07.006CrossRefPubMed

51.

von Mehren M (2023) National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: soft tissue sarcoma. Version 3.2023. Available via https://www.nccn.org/professionals/physician_gls/pdf/sarcoma.pdf. Accessed 12 Dec 2023

52.

Patel SA, Royce TJ, Barysauskas CM, Thornton KA, Raut CP, Baldini EH (2017) Surveillance imaging patterns and outcomes following radiation therapy and radical resection for localized extremity and trunk soft tissue sarcoma. Ann Surg Oncol 24:1588–1595. https://doi.org/10.1245/s10434-016-5755-5CrossRefPubMed

53.

Expert Panel on Musculoskeletal I, Stanborough R, Demertzis JL et al (2022) ACR Appropriateness Criteria® malignant or aggressive primary musculoskeletal tumor-staging and surveillance: 2022 update. J Am Coll Radiol 19:S374–S389. https://doi.org/10.1016/j.jacr.2022.09.015CrossRef

54.

Gamboa AC, Ethun CG, Switchenko JM et al (2019) Lung surveillance strategy for high-grade soft tissue sarcomas: chest X-ray or CT scan? J Am Coll Surg 229:449–457. https://doi.org/10.1016/j.jamcollsurg.2019.07.010CrossRefPubMedPubMedCentral

55.

Blaye C, Kind M, Stoeckle E et al (2019) Local and metastatic relapse features in patients after a primary soft tissue sarcoma: advocating for a better-tailored follow-up. Front Oncol 9:559. https://doi.org/10.3389/fonc.2019.00559CrossRefPubMedPubMedCentral

56.

Roberts CC, Kransdorf MJ, Beaman FD et al (2016) ACR appropriateness criteria follow-up of malignant or aggressive musculoskeletal tumors. J Am Coll Radiol 13:389–400. https://doi.org/10.1016/j.jacr.2015.12.019CrossRefPubMed

57.

Macpherson RE, Pratap S, Tyrrell H et al (2018) Retrospective audit of 957 consecutive ¹⁸F-FDG PET-CT scans compared to CT and MRI in 493 patients with different histological subtypes of bone and soft tissue sarcoma. Clin Sarcoma Res 8:9. https://doi.org/10.1186/s13569-018-0095-9CrossRefPubMedPubMedCentral

58.

Kassem TW, Abdelaziz O, Emad-Eldin S (2017) Diagnostic value of ¹⁸F-FDG-PET/CT for the follow-up and restaging of soft tissue sarcomas in adults. Diagn Interv Imaging 98:693–698. https://doi.org/10.1016/j.diii.2017.06.006CrossRefPubMed

59.

Fine GC, Covington MF, Koppula BR et al (2022) PET-CT in clinical adult oncology-VI. Primary cutaneous cancer, sarcomas and neuroendocrine tumors. Cancers (Basel) https://doi.org/10.3390/cancers14122835

60.

Basile G, Mattei JC, Alshaygy I et al (2020) Curability of patients with lymph node metastases from extremity soft-tissue sarcoma. Cancer 126:5098–5108. https://doi.org/10.1002/cncr.33189CrossRefPubMed

61.

Zampa V, Aringhieri G, Tintori R, Rossi P, Andreani L, Franchi A (2023) The added value of the visual analysis of DWI in post-surgery follow-up of soft tissue sarcoma of the extremities: do we really need ADC? Radiol Med 128:467–479. https://doi.org/10.1007/s11547-023-01613-wCrossRefPubMedPubMedCentral

62.

Afonso DP, Kosinski AS, Spritzer CE (2013) Following unenhanced MRI assessment for local recurrence after surgical resection of mesenchymal soft tissue tumors, do additional gadolinium-enhanced images change reader confidence or diagnosis? Eur J Radiol 82:806–813. https://doi.org/10.1016/j.ejrad.2012.11.025CrossRef

63.

Chou SS, Hippe DS, Lee AY et al (2017) Gadolinium contrast enhancement improves confidence in diagnosing recurrent soft tissue sarcoma by MRI. Acad Radiol 24:615–622. https://doi.org/10.1016/j.acra.2016.12.010CrossRefPubMed

64.

Hirschmann A, van Praag VM, Haas RL, van de Sande MAJ, Bloem JL (2020) Can we use MRI to detect clinically silent recurrent soft-tissue sarcoma? Eur Radiol 30:4724–4733. https://doi.org/10.1007/s00330-020-06810-zCrossRefPubMed

65.

Schwab JH, Boland PJ, Antonescu C, Bilsky MH, Healey JH (2007) Spinal metastases from myxoid liposarcoma warrant screening with magnetic resonance imaging. Cancer 110:1815–1822. https://doi.org/10.1002/cncr.22992CrossRefPubMed

66.

Lin S, Gan Z, Han K, Yao Y, Min D (2015) Metastasis of myxoid liposarcoma to fat-bearing areas: a case report of unusual metastatic sites and a hypothesis. Oncol Lett 10:2543–2546. https://doi.org/10.3892/ol.2015.3585CrossRefPubMedPubMedCentral

67.

Durr HR, Rauh J, Baur-Melnyk A et al (2018) Myxoid liposarcoma: local relapse and metastatic pattern in 43 patients. BMC Cancer 18:304. https://doi.org/10.1186/s12885-018-4226-8CrossRefPubMedPubMedCentral

68.

Stevenson JD, Watson JJ, Cool P et al (2016) Whole-body magnetic resonance imaging in myxoid liposarcoma: a useful adjunct for the detection of extra-pulmonary metastatic disease. Eur J Surg Oncol 42:574–580. https://doi.org/10.1016/j.ejso.2015.12.011CrossRefPubMed

69.

Gorelik N, Reddy SMV, Turcotte RE et al (2018) Early detection of metastases using whole-body MRI for initial staging and routine follow-up of myxoid liposarcoma. Skeletal Radiol 47:369–379. https://doi.org/10.1007/s00256-017-2845-9CrossRefPubMed

70.

Seo SW, Kwon JW, Jang SW, Jang SP, Park YS (2011) Feasibility of whole-body MRI for detecting metastatic myxoid liposarcoma: a case series. Orthopedics 34:e748–e754. https://doi.org/10.3928/01477447-20110922-15CrossRefPubMed

71.

Matsui JK, Jackson S, Fang J et al (2024) Effect of palliative radiation dose on symptom response in metastatic sarcomas. Clin Transl Radiat Oncol 48:100803. https://doi.org/10.1016/j.ctro.2024.100803CrossRefPubMedPubMedCentral

72.

Gutkin PM, von Eyben R, Chin A et al (2022) Local control outcomes using stereotactic body radiation therapy or surgical resection for metastatic sarcoma. Int J Radiat Oncol Biol Phys 114:771–779. https://doi.org/10.1016/j.ijrobp.2022.05.017CrossRefPubMed

73.

Grilley-Olson JE, Webber NP, Demos DS, Christensen JD, Kirsch DG (2018) Multidisciplinary management of oligometastatic soft tissue sarcoma. Am Soc Clin Oncol Educ Book 38:939–948. https://doi.org/10.1200/EDBK_200573CrossRefPubMed

74.

Damery S, Biswas M, Billingham L, Barton P, Al-Janabi H, Grimer R (2014) Patient preferences for clinical follow-up after primary treatment for soft tissue sarcoma: a cross-sectional survey and discrete choice experiment. Eur J Surg Oncol 40:1655–1661. https://doi.org/10.1016/j.ejso.2014.04.020CrossRefPubMed

Title: Soft tissue tumor imaging in adults: European Society of Musculoskeletal Radiology–Guidelines 2024: imaging immediately after neoadjuvant therapy in soft tissue sarcoma, soft tissue tumor surveillance, and the role of interventional radiology
Authors: Iris-Melanie Noebauer-Huhmann
Joan C. Vilanova
Olympia Papakonstantinou
Marc-André Weber
Radhesh K. Lalam
Violeta Vasilevska Nikodinovska
Hatice T. Sanal
Frédéric E. Lecouvet
Ana Navas
José Martel-Villagrán
Jacky W. J. de Rooy
Jan Fritz
Koenraad Verstraete
Thomas Grieser
Pavol Szomolanyi
Snehansh Chaudhary
Luca Maria Sconfienza
Alberto S. Tagliafico
P. Diana Afonso
Omar M. Albtoush
Giacomo Aringhieri
Remide Arkun
Gunnar Aström
Alberto Bazzocchi
Rajesh Botchu
Martin Breitenseher
Danoob Dalili
Mark Davies
Milko C. de Jonge
Berna D. Mete
Jan L. M. A. Gielen
Geoff Hide
Amanda Isaac
Slavcho Ivanoski
Ramy M. Mansour
Catherine Mccarthy
Lorenzo Muntaner-Gimbernat
Paul O’Donnell
Şebnem Örgüç
Winston J. Rennie
Santiago Resano
Philip Robinson
Simone A. J. Ter Horst
Kirsten van Langevelde
Klaus Wörtler
Marita Koelz
Joannis Panotopoulos
Reinhard Windhager
Barbara J. Fueger
Maximilian Schmid
Filip M. Vanhoenacker
Publication date: 18-12-2024
Publisher: Springer Berlin Heidelberg
Keywords: Sarcoma
Soft Tissue Tumor
Soft Tissue Sarcoma
Magnetic Resonance Imaging
Magnetic Resonance Imaging
Interventional Radiology
Musculoskeletal Radiology
Published in: European Radiology
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-024-11242-0

Podcast | Sexual health in older age

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Soft tissue tumor imaging in adults: European Society of Musculoskeletal Radiology–Guidelines 2024: imaging immediately after neoadjuvant therapy in soft tissue sarcoma, soft tissue tumor surveillance, and the role of interventional radiology

Abstract

Objectives

Materials and methods

Results

Conclusion

Key Points

Podcast | Sexual health in older age

Springer Medicine

Abstract

Objectives

Materials and methods

Results

Conclusion

Key Points

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