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13-02-2024 | Research

Risk factors associated with intraventricular hemorrhage in very-low-birth-weight premature infants

Authors: Alejandra Guadalupe Puerta-Martínez, Esteban López-Garrido, José Miguel Guerrero-Nava, Rodrigo Vargas-Ruiz, Hadassa Yuef Martínez-Padrón

Published in: Child's Nervous System | Issue 6/2024

Abstract

Purpose

To analyze the association between risk factors and severe intraventricular hemorrhage (grade II–IV) in PNB under 1500 g.

Methods

Multicenter, retrospective, analytical, case–control study in PNB under 34 weeks and under 1500 g admitted to the NICU. Case: PNB with severe intraventricular hemorrhage (grade II–IV). Logistic regression analysis was used to adjust for IVH-associated variables and odds ratios (OR).

Results

A total of 90 PNB files were analyzed, 45 cases and 45 controls. The highest risk factors for severe IVH were lower gestational age (OR 1.3, p < 0.001), perinatal asphyxia (OR 12, p < 0.001), Apgar < 6 at minute 1 and 5 (OR 6.3, p < 0.001).

Conclusion

Lower gestational age, birth asphyxia, Apgar score lower of 6, and respiratory-type factors are associated with increased risk for severe IVH.

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Title: Risk factors associated with intraventricular hemorrhage in very-low-birth-weight premature infants
Authors: Alejandra Guadalupe Puerta-Martínez
Esteban López-Garrido
José Miguel Guerrero-Nava
Rodrigo Vargas-Ruiz
Hadassa Yuef Martínez-Padrón
Publication date: 13-02-2024
Publisher: Springer Berlin Heidelberg
Published in: Child's Nervous System / Issue 6/2024
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI: https://doi.org/10.1007/s00381-024-06310-1

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Risk factors associated with intraventricular hemorrhage in very-low-birth-weight premature infants

Abstract

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