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Internal Medicine Rheumatology

Rheumatology

Recommendations for the use of generative AI in medicine

This position statement from the SGIM serves as a guide for exploring how generative AI may benefit medical practice, focusing on clinical decision-making, health systems optimization, and the patient–physician relationship.

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Editor's Choice

Anastrozole boosts growth potential in children with CAH

Anastrozole could help optimize growth for children with congenital adrenal hyperplasia and advanced bone age.

Better pain relief with total hip replacement for hip osteoarthritis

Total hip replacement for severe hip osteoarthritis significantly improves pain and function in adults aged 50 years or older compared with resistance training.

Semaglutide shows promise for obesity-related osteoarthritis

STEP 9 trial results suggest that treatment with semaglutide may significantly reduce both bodyweight and knee pain in people with obesity and knee osteoarthritis.

Romosozumab for the treatment of osteoporosis

The monoclonal antibody romosozumab has a transient but robust bone anabolic effect. Find out what is currently known about its clinical efficacy and safety for the treatment of primary and secondary osteoporosis.

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Case Studies

Triple vessel spontaneous CAD in polyarteritis nodosa

Triple-vessel spontaneous coronary artery dissection and polyarteritis nodosa are both extremely rare. Their coexistence is exceptional and presents unique diagnostic and therapeutic challenges.

Combined treatment for PML

Progressive multifocal leukoencephalopathy is an often fatal CNS disease caused by JC virus infection. In this case, low-dose, long-term immunoglobulin plus mirtazapine resulted in a controlled inflammatory reaction.

Lumbar sympathetic block to treat CRPS in a toddler

After non-invasive measures failed, a lumbar sympathetic block performed with extreme caution alleviated complex regional pain syndrome in this 18-month-old.

Current Reviews

An Overview of Osteoporosis and Possible Treatment Approaches

Osteoporosis is most prevalent in postmenopausal women and is a widespread condition that impacts millions of individuals worldwide. A decrease in bone mineral density and elevated susceptibility to fractures as a result of bone architecture …

Natural Products and Traditional Herbal Medicines as Managerial Therapies to Combat Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a complex and challenging autoimmune disease characterized by chronic inflammation of the joints, discomfort, stiffness, functional impairment, and systemic complications that affect millions of people around the …

Therapeutic potential of exosomes derived from mesenchymal stem cells for treatment of systemic lupus erythematosus

Autoimmune diseases are caused by an imbalance in the immune system, producing autoantibodies that cause inflammation leading to tissue damage and organ dysfunction. Systemic Lupus Erythematosus (SLE) is one of the most common autoimmune diseases …

Efficacy and safety of current therapies for difficult-to-treat rheumatoid arthritis: a systematic review and network meta-analysis

Rheumatoid arthritis (RA) is a common and chronic inflammatory autoimmune disease characterized by destructive, chronic, debilitating arthritis [ 1 ]. According to the European Alliance of Associations for Rheumatology (EULAR) RA management …

Further Reading

Integrated model of secondary fracture prevention in primary care (INTERCEPT): protocol for a cluster randomised controlled multicentre trial

Osteoporosis is a common chronic condition characterised by loss of bone mass and strength, resulting in fractures following trauma that is normally insufficient to cause such injuries (referred to as ‘minimal trauma’ or ‘fragility’ fractures). It …

Barriers and facilitators to using a clinical decision support tool for the management of osteoarthritis pain in patients undergoing hemodialysis: a qualitative study

Osteoarthritis is a significant cause of suffering for patients with end stage kidney disease undergoing hemodialysis [ 1 – 5 ]. Chronic pain related to osteoarthritis leads to functional limitations, disability, social isolation, sleep disorders …

Patterns of knee osteoarthritis management in general practice: a retrospective cohort study using electronic health records

Osteoarthritis (OA) is a highly prevalent progressive joint disease, causing pain and reduced function of the joint. It has been ranked as the 10th leading contributor to global disability [ 1 – 3 ]. Based on general practitioner (GP) registries …

Therapeutic potential of exosomes derived from mesenchymal stem cells for treatment of systemic lupus erythematosus

Autoimmune diseases are caused by an imbalance in the immune system, producing autoantibodies that cause inflammation leading to tissue damage and organ dysfunction. Systemic Lupus Erythematosus (SLE) is one of the most common autoimmune diseases …