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A rare case of purulent pericardial effusion secondary to methicillin-sensitive Staphylococcus aureus in a patient with systemic lupus erythematosus that highlights asymptomatic bacteriuria as a potential early indicator.
Explore recent advances in precision medicine and novel targeted therapies in rheumatoid arthritis, which may lead to better disease control or possibly cure in the future.
The 5-year risk for major adverse cardiovascular events in people with gout is significantly lower if they achieve the serum urate-lowering treatment target than if they do not.
What are the clinical and pathological features of immune thrombocytopenia secondary to systemic lupus erythematosus and Sjögren syndrome? And how can current and emerging therapeutic strategies improve outcomes?
Learn more about the importance of adapting treatment approaches for special patient populations (eg, elderly or pregnant patients) in this third module of our interactive e-Learning program on diagnosing and treating aplastic anemia.
A rare case of purulent pericardial effusion secondary to methicillin-sensitive Staphylococcus aureus in a patient with systemic lupus erythematosus that highlights asymptomatic bacteriuria as a potential early indicator.
An 81-year-old receiving upadacitinib for rheumatoid arthritis developed CMV retinitis complicated by delayed retinal ischemia and vitreous hemorrhage. Clinicians should be vigilant for atypical ocular complications from JAK inhibitors.
A disease flare in this patient with granulomatosis with polyangiitis was indicated by strawberry gingiva. Early recognition of SG is essential for timely diagnosis and it also serves as a valuable marker of therapeutic response.
In this special edition of Medicine Matters, we're joined by Dr Gregory Lim, Claire Greenhill, and Sarah Onuora, Chief Editors of Nature Reviews Cardiology, Endocrinology, and Rheumatology, for a look back at the advances in their specialties in 2025.
Find out what caught their attention and why, and what they're looking forward to in 2026.
Septic arthritis of the knee is an acute infection that can rapidly destroy articular cartilage if not promptly recognized and treated. Early diagnosis is often difficult because symptoms overlap with crystal or inflammatory arthropathies and …
This systematic review and meta-analysis evaluated the efficacy of light therapy in reducing PTSD symptoms across six randomized controlled trials (RCTs), including 312 participants. Standardized mean differences (SMDs) were calculated, revealing …
Granulomatosis with polyangiitis (GPA) is a systemic vasculitis characterized by necrotizing granulomatous inflammation affecting small- and medium-sized blood vessels. The disease predominantly targets the respiratory tract and kidneys, but the …
Dermatomyositis (DM) is an autoimmune inflammatory myopathy that may occur as a paraneoplastic syndrome, most commonly associated with ovarian, lung, and gastrointestinal malignancies. Solid pseudopapillary pancreatic tumor is a rare neoplasm with …
Systemic lupus erythematosus is a severe autoimmune disease that can cause damage to almost every system of the body. Learn more about novel biomarkers for diagnosis and monitoring, and familiarize yourself with current and emerging targeted therapies.
Transform the way you care for your patients with aplastic anemia with our 3-module eLearning series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases.
Sarcoidosis is a multisystem granulomatous disease that has nonspecific clinical manifestations that commonly affect the pulmonary system in at least 90% of sarcoidosis patients. In 10–30% of cases there is involvement of other organs such as the …
Uncontrolled gout (UG) is a progressive arthropathy that develops as a consequence of sustained hyperuricemia. Recombinant uricases can profoundly lower serum urate (SU) and reverse the clinical manifestations of uncontrolled gout. However …
Sarcoidosis is a systemic inflammatory disease characterized by non-caseating granulomas, mainly affecting the lungs, eyes, and skin [ 1 – 4 ]. The prevalence of renal involvement ranges from approximately −1% to 5% [ 2 , 4 – 6 ]. Common renal …
Systemic sclerosis-associated interstitial lung disease (SSc-ILD) is a major cause of morbidity and mortality in systemic sclerosis [ 1 ]. Its clinical course is highly heterogeneous with 30% exhibiting progressive decline [ 2 – 4 ]. Current …
In a large database analysis, use of GLP-1 receptor agonists was associated with a reduced symptom burden in people with fibromyalgia, but further studies with validated outcome measures are needed.
Infrapatellar fat pad glucocorticoid injections were no better than placebo for reducing knee osteoarthritis pain or inflammation in a randomized controlled trial.
Adding a conventional synthetic disease-modifying antirheumatic drug to first-line systemic corticosteroid therapy may reduce treatment failure in patients with nonanterior sarcoidosis-associated uveitis.