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An infant diagnosed with Kawasaki disease developed impetigo-like psoriasiform eruption that was refractory to oral antibiotics and topical steroids and only improved after treatment with oral prednisolone.
Interstitial lung disease is the most severe extra-articular manifestations of rheumatoid arthritis. What is known about its pathogenesis and how does that inform treatment options?
IgAV can develop after the diagnosis of IBD, manifesting in the skin, joints, kidneys, and GI tract, but are people with IgAV at risk of IBD? Investigate the interplay between the two, including risk and protective factors.
A rare case of purulent pericardial effusion secondary to methicillin-sensitive Staphylococcus aureus in a patient with systemic lupus erythematosus that highlights asymptomatic bacteriuria as a potential early indicator.
Learn more about the importance of adapting treatment approaches for special patient populations (eg, elderly or pregnant patients) in this third module of our interactive e-Learning program on diagnosing and treating aplastic anemia.
An infant diagnosed with Kawasaki disease developed impetigo-like psoriasiform eruption that was refractory to oral antibiotics and topical steroids and only improved after treatment with oral prednisolone.
A rare case of purulent pericardial effusion secondary to methicillin-sensitive Staphylococcus aureus in a patient with systemic lupus erythematosus that highlights asymptomatic bacteriuria as a potential early indicator.
An 81-year-old receiving upadacitinib for rheumatoid arthritis developed CMV retinitis complicated by delayed retinal ischemia and vitreous hemorrhage. Clinicians should be vigilant for atypical ocular complications from JAK inhibitors.
In this special edition of Medicine Matters, we're joined by Dr Gregory Lim, Claire Greenhill, and Sarah Onuora, Chief Editors of Nature Reviews Cardiology, Endocrinology, and Rheumatology, for a look back at the advances in their specialties in 2025.
Find out what caught their attention and why, and what they're looking forward to in 2026.
Dermatomyositis is a rare autoimmune disease characterized by muscle weakness and distinctive skin rashes. Patients typically present with symmetric proximal muscle weakness alongside extramuscular manifestations, including interstitial lung …
The subchondral bone is an integral structural component of the knee with key roles in shock absorption and load distribution. Injuries to the subchondral bone, which may occur secondary to various etiologies including trauma, degenerative …
Axial spondyloarthritis (axSpA) is a chronic, inflammatory, immune-mediated disease characterized by inflammation of the axial skeleton, peripheral joints, and entheses. Patients with axSpA often experience a long diagnostic delay, and if left …
Methotrexate (MTX) remains the first-line pharmacotherapy for rheumatoid arthritis (RA), yet gastrointestinal (GI) adverse events (AEs) are frequently reported. This systematic review and meta-analysis aimed to estimate the prevalence of GI AEs …
Systemic lupus erythematosus is a severe autoimmune disease that can cause damage to almost every system of the body. Learn more about novel biomarkers for diagnosis and monitoring, and familiarize yourself with current and emerging targeted therapies.
Transform the way you care for your patients with aplastic anemia with our 3-module eLearning series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases.
Breast cancer (BC) is the most common cancer in women worldwide [ 1 ]. Approximately 80% of BC is hormone receptor positive and may be amenable to hormone deprivation therapies (HDTs), which are usually administered early in the course of the …
Knee osteoarthritis (KOA) is a highly prevalent degenerative joint disorder [ 1 ], predominantly affecting middle-aged and elderly individuals, with an estimated global burden of approximately 654 million people [ 2 ]. Clinically, KOA is marked by …
Dermatomyositis is a rare autoimmune disease characterized by muscle weakness and distinctive skin rashes. Patients typically present with symmetric proximal muscle weakness alongside extramuscular manifestations, including interstitial lung …
Sarcoidosis is a rare, idiopathic, chronic granulomatous disease of unknown cause that primarily affects the lungs in 80–90% of cases [ 1 , 2 ]. The prevalence of sarcoidosis in the United States (U.S.) is estimated to be 60 per 100,000 adults, and …
In a large database analysis, use of GLP-1 receptor agonists was associated with a reduced symptom burden in people with fibromyalgia, but further studies with validated outcome measures are needed.
Infrapatellar fat pad glucocorticoid injections were no better than placebo for reducing knee osteoarthritis pain or inflammation in a randomized controlled trial.
Adding a conventional synthetic disease-modifying antirheumatic drug to first-line systemic corticosteroid therapy may reduce treatment failure in patients with nonanterior sarcoidosis-associated uveitis.