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Internal Medicine Rheumatology

Rheumatology

Unconventional imaging methods in psoriatic arthritis

Novel imaging modalities that enable both structural and molecular characterization hold great promise for improving the understanding of psoriatic arthritis. How can these technologies help advance the field toward personalized medicine?

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Editor's Choice

Infrequent zoledronate fights postmenopausal vertebral fracture risk

Women with a healthy bone mineral density may benefit from occasional infusions of zoledronate between age 50 and 60 years.

Allogeneic HSCT promising for treating lung disease in JIA

Lung disease associated with refractory systemic juvenile idiopathic arthritis appears to be improved by allogeneic hematopoietic stem cell transplantation.

Spondyloarthritis and cancer risk

The risk for malignancy in people with spondyloarthritis remains a controversial issue. What is the current evidence for the impact of the disease and its treatment with biologic and targeted synthetic DMARDs?

Rare initial manifestation of SLE

A patient with systemic lupus erythematosus was initially diagnosed with Evans syndrome, an autoimmune hematologic disorder. The case was further complicated by the co-existence of Hashimoto’s thyroiditis and pernicious anemia.

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Case Studies

Rare initial manifestation of SLE

A patient with systemic lupus erythematosus was initially diagnosed with Evans syndrome, an autoimmune hematologic disorder. The case was further complicated by the co-existence of Hashimoto’s thyroiditis and pernicious anemia.

Polyarteritis nodosa presenting with severe GI bleeding

Although gastrointestinal involvement is known in polyarteritis nodosa, severe gastrointestinal bleeding due to gastric ulceration is relatively uncommon. This case sheds light on this rare complication.

Atypical Kawasaki disease in a 2-month-old boy

A case underscoring the importance of considering Kawasaki disease in infants presenting with prolonged, antibiotic-resistant fever, even though the condition is uncommon in children younger than 6 months.

Current Reviews

Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024. Part 3: solid cancers and vascular abnormalities

This study discusses disseminated intravascular coagulation (DIC) associated with solid cancers and various vascular abnormalities, both of which generally exhibit chronic DIC patterns. Solid cancers are among the most significant underlying …

Imaging and management of calcium pyrophosphate deposition disease

The radiological manifestations of calcium pyrophosphate deposition (CPPD) revolve around two main axes: the asymptomatic form and CPPD disease. The latter is a consequence of an immune response to calcium phosphate crystals. Chondrocalcinosis is …

Osteoporosis in Older Men: Informing Patient Management and Improving Health-Related Outcomes

Osteoporosis has been usually considered a female disease, generally causing more fracture risk and complications in adult and older women compared to older men. While vertebral fractures occur in a small proportion of men during middle age, men …

Unraveling the hormonal approaches for the treatment of rheumatoid arthritis and its complementary interventions

Rheumatoid Arthritis (RA) is an autoimmune, chronic, systemic inflammatory disease that causes redness, swelling, stiffness, and joint pain. It is a long-lasting disease that can have a widespread impact on the body, often affecting the hands …

Further Reading

Post-mortem diagnosis of septic arthritis by Pasteurella multocida: a case report and literature review of fatal septic arthritis

The diagnosis of septic arthritis remains challenging in the clinical setting, often leading to a suspicion for medical liability. Our purpose is to describe an unusual case of a post-mortem diagnosis of P. multocida fatal septic arthritis, in a …

Familial Mediterranean fever with sigmoid colon stricture

We describe a case of familial Mediterranean fever (FMF) with sigmoid colon stricture. The patient, a woman in her 30 s, had a 12-year history of ileocolitis-type Crohn’s disease. The colonoscope could not pass because of the sigmoid colon …

Osteoporosis and stroke: a bidirectional mendelian randomization study

Osteoporosis and stroke are significant public health concerns worldwide. [ 1 , 2 ] Stroke is a leading cause of disability and death, affecting approximately 15 million people each year, and its prevalence is expected to increase with the aging …

Reliability and validity of the Londrina activities of daily living protocol in individuals with systemic sclerosis

Systemic sclerosis (SSc) is a connective tissue disease characterized by fibrosis of the skin, musculoskeletal system, and internal organs associated with vasculopathy and late-stage tissue atrophy [ 1 ]. It is classified into two main subgroups: …