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Internal Medicine Rheumatology

Rheumatology

POETYK trial shows clinical benefit of deucravacitinib in PsA

Treatment with the TYK2 inhibitor deucravacitinib improved disease activity, joint and skin symptoms, and quality of life among people with active psoriatic arthritis participating in the POETYK PsA-1 trial 

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Editor's Choice

Diagnostic dilemma: neuropsychiatric lupus or WNV encephalitis?

Neuropsychiatric SLE and infections, such as West Nile encephalitis, can be difficult to differentiate, as demonstrated by these cases. This challenge is vital to overcome due to the opposing management strategies.

DMARDs boost treatment success in nonanterior sarcoidosis-associated uveitis

Adding a conventional synthetic disease-modifying antirheumatic drug to first-line systemic corticosteroid therapy may reduce treatment failure in patients with nonanterior sarcoidosis-associated uveitis.

SSc tied to increased cardiovascular, thromboembolic risk

Patients with systemic sclerosis have an increased risk for cardiovascular disease and venous thromboembolism before and after diagnosis.

Rheumatoid arthritis and family planning

Equip yourself to counsel your patients with rheumatoid arthritis about reproductive health concerns, such as contraception safety, infertility, and the management of RA medications during pregnancy and breastfeeding.

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EULAR 2025

Explore the latest news and updates from the annual congress of the European Alliance of Associations for Rheumatology.

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Latest News

Reduction in MACE risk an additional benefit of treat to target in gout

  • 19-06-2025
  • Gout
  • News

POETYK trial shows clinical benefit of deucravacitinib in PsA

Patient-perceived residual symptoms predict axSpA flare-ups

Higher JIA risk after fertility treatment, especially in boys

Persistence and efficacy of ixekizumab versus other DMARDs in PsA

Can social robots replace the rheumatologist?

Case Studies

Diagnostic dilemma: neuropsychiatric lupus or WNV encephalitis?

Neuropsychiatric SLE and infections, such as West Nile encephalitis, can be difficult to differentiate, as demonstrated by these cases. This challenge is vital to overcome due to the opposing management strategies.

Kidney involvement in VEXAS syndrome

VEXAS syndrome is a recently identified genetic autoinflammatory disorder. This case highlights its under-recognized renal manifestations and underscores the need for heightened clinical suspicion and earlier intervention.

Takayasu arteritis complicated by SAPHO syndrome

Two patients presenting with anterior chest pain were diagnosed with Takayasu arteritis co-existing with SAPHO syndrome, a rare inflammatory osteoarticular disorder. Their symptoms improved with glucocorticoids and biologic agents.

Keynote webinar | Spotlight on advances in lupus

Systemic lupus erythematosus is a severe autoimmune disease that can cause damage to almost every system of the body. Learn more about novel biomarkers for diagnosis and monitoring, and familiarize yourself with current and emerging targeted therapies.

Prof. Edward Vital
Prof. Ronald F. van Vollenhoven
Developed by: Springer Medicine
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Current Reviews

Public Health Impact of Kawasaki Disease in India: Projections for 2030

Kawasaki disease (KD) is a systemic vasculitis that usually affects children below 5 years and has now become the leading cause of acquired heart disease in children, surpassing acute rheumatic fever. Incidence data from Chandigarh, India, between …

Patient education following vertebral fragility fracture: a scoping review

Vertebral fragility fractures (VFFs) are one of the most common fractures among individuals with osteoporosis [ 1 ], with approximately 20% of the older population expected to sustain a VFF [ 2 ]. Reported VFF incidence varies, in part, reflecting …

Efficacy of rituximab versus cyclophosphamide in connective tissue disease‑related interstitial lung disease: a systematic review and meta-analysis

Connective tissue disease (CTD) is a type of autoimmune disease that causes multisystem damage based on chronic inflammation of blood vessels and connective tissue. Because lungs are rich in connective tissues such as collagen and blood vessels …

Allogeneic hematopoietic cell transplantation for autoinflammatory disorders

The understanding of autoinflammatory disorders, which are caused by the dysregulated activation of the innate immune system, has improved with the discovery of new diseases and the expansion of phenotypes. Inflammation can be controlled using …

Episode 17: Challenges of developing DMOADs

Why are disease-modifying treatments for osteoarthritis such a difficult proposition?

Despite multiple attempts, no DMOAD is yet approved for clinical use. Prof. Ali Mobasheri takes us through the main challenges, the work being done to make these so-called utopia drugs a reality, and discusses other advances that offer hope in the meantime.

Prof. Ali Mobasheri
Listen now
Podcast

CME & eLearning

eLearning (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Health+ IME

Further Reading

Clinical Outcomes of Patients with SLE Treated with Belimumab, Without Versus With Prior Immunosuppressant Use: a US Claims Database Study

Systemic lupus erythematosus (SLE) is a chronic and debilitating autoimmune disease that is associated with decreased quality of life and increased mortality risk [ 1 ]. Earlier diagnosis and treatment of SLE improves patient prognosis and quality …

Intraocular inflammation following intravitreal injections of anti-vascular endothelial growth factor drugs

The Intravitreal injections (IVI) of anti-vascular endothelial growth factor (VEGF) agents are commonly used as the treatment of choice for patients with macular neovascularization or macular edema from different etiologies, aiming to improve both …

Patient education following vertebral fragility fracture: a scoping review

Vertebral fragility fractures (VFFs) are one of the most common fractures among individuals with osteoporosis [ 1 ], with approximately 20% of the older population expected to sustain a VFF [ 2 ]. Reported VFF incidence varies, in part, reflecting …

CD11b as a diagnostic biomarker of rheumatoid arthritis and as a risk factor of periodontitis: a pilot study

This study aimed to explore the role of CD11b, CD38, and HLA-DR in saliva, linking rheumatoid arthritis (RA) and periodontitis. We hypothesized that their expression reflects shared immunological pathways and correlates with clinical periodontal …

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Lumbar sympathetic block to treat CRPS in a toddler

After non-invasive measures failed, a lumbar sympathetic block performed with extreme caution alleviated complex regional pain syndrome in this 18-month-old.

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Illness uncertainty in hypermobile Ehlers-Danlos syndrome

Neurostimulation therapies for chronic pain

POETYK trial shows clinical benefit of deucravacitinib in PsA

Treatment with the TYK2 inhibitor deucravacitinib improved disease activity, joint and skin symptoms, and quality of life among people with active psoriatic arthritis participating in the POETYK PsA-1 trial 

Read more

Diagnostic dilemma: neuropsychiatric lupus or WNV encephalitis?

DMARDs boost treatment success in nonanterior sarcoidosis-associated uveitis

SSc tied to increased cardiovascular, thromboembolic risk

Rheumatoid arthritis and family planning

Kidney involvement in VEXAS syndrome

Heterotopic ossification after wrist replacement

The first reported case of heterotopic ossification following total wrist arthroplasty. Revision surgery was performed to remove ossifications and no further signs have been reported, but the patient's range of motion remains reduced.

Read more

Trial supports metformin use in osteoarthritis

Osteoporosis and osteoarthritis in elderly patients

Biomarkers in hand osteoarthritis

Use of platelet-rich plasma in rheumatic diseases

Are heated mittens useful in osteoarthritis?

DMARDs boost treatment success in nonanterior sarcoidosis-associated uveitis

Adding a conventional synthetic disease-modifying antirheumatic drug to first-line systemic corticosteroid therapy may reduce treatment failure in patients with nonanterior sarcoidosis-associated uveitis.

Read more

Ulcerative cutaneous sarcoidosis: a diagnostic challenge

ALS in a patient with CLL and drug-related SLR

Cardio-rheumatology: an emerging specialty

Corticosteroids for hydrocephalus in neurosarcoidosis

Complications from conduction system pacing

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