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Internal Medicine Rheumatology

Rheumatology

Ulcerative cutaneous sarcoidosis: a diagnostic challenge

Diagnosing cutaneous sarcoidosis can be challenging due to its diverse skin manifestations, which can mimic other conditions. In this case, the patient presented with chronic leg ulcers.

Read more

Editor's Choice

Trial supports metformin use in osteoarthritis

Treatment with the diabetes medication metformin significantly reduces knee pain in patients with symptomatic knee osteoarthritis who have overweight or obesity.

How to approach statin therapy in vulnerable groups

Statins can be key to preventing ASCVD but remain underused in vulnerable populations, such as those with CKD, MASLD, HIV, lupus and other immune-associated inflammatory conditions. What should be considered when treating these groups?

Association of IgA vasculitis with rare leukemia

This first report of IgA vasculitis associated with chronic myelomonocytic leukemia highlights the need for awareness of underlying hematologic malignancies in patients presenting with unexplained vasculitis.

Izokibep shows potential for psoriatic arthritis

Phase 2 data show that the small protein therapeutic izokibep significantly reduces disease activity in people with active psoriatic arthritis versus placebo.

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Episode 17: Challenges of developing DMOADs

Why are disease-modifying treatments for osteoarthritis such a difficult proposition?

Despite multiple attempts, no DMOAD is yet approved for clinical use. Prof. Ali Mobasheri takes us through the main challenges, the work being done to make these so-called utopia drugs a reality, and discusses other advances that offer hope in the meantime.

Prof. Ali Mobasheri
Listen now
Podcast

Latest News

Trial supports metformin use in osteoarthritis

Izokibep shows potential for psoriatic arthritis

Study supports first-line biologics for Still disease

Upadacitinib may offer a glucocorticoid-sparing option for GCA

Reduced infection risk with IL-targeting biologics

Pros and cons of glucocorticoid cessation

Case Studies

Ulcerative cutaneous sarcoidosis: a diagnostic challenge

Diagnosing cutaneous sarcoidosis can be challenging due to its diverse skin manifestations, which can mimic other conditions. In this case, the patient presented with chronic leg ulcers.

Association of IgA vasculitis with rare leukemia

This first report of IgA vasculitis associated with chronic myelomonocytic leukemia highlights the need for awareness of underlying hematologic malignancies in patients presenting with unexplained vasculitis.

Novel association of chilblains with inflammatory arthritis

Three patients with inflammatory arthritis had concomitant chilblains and bone marrow edema as revealed by MRI. Could this trifecta represent a new clinical phenotype of seronegative spondyloarthropathies?

Keynote webinar | Spotlight on advances in lupus

  • Live
  • Webinar | 27-05-2025 | 18:00 (CEST)

Systemic lupus erythematosus is a severe autoimmune disease that can cause damage to almost every system of the body. Join this session to learn more about novel biomarkers for diagnosis and monitoring and familiarise yourself with current and emerging targeted therapies.

Join us live: Tuesday 27th May, 18:00-19:15 (CEST)

Prof. Edward Vital
Prof. Ronald F. van Vollenhoven
Developed by: Springer Medicine
Register now
Webinar

Current Reviews

Sauna therapy in rheumatic diseases: mechanisms, potential benefits, and cautions

Rheumatic diseases (RDs) present a major global health challenge, particularly in aging populations, due to chronic inflammation, progressive joint damage, and impaired mobility. While pharmacologic interventions, such as non-steroidal …

A case-based review of IgA vasculitis complicated with gastrointestinal infections: insights from a norovirus-associated case in an adolescent

Immunoglobulin A vasculitis (IgAV), formerly known as Henoch-Schönlein purpura, is a self-limited leukocytoclastic vasculitis targeting small-sized vessels. It is the most common vasculitis in children, but also targets adults who have usually …

Current concepts on pathogenesis, diagnosis and management of hepatic sarcoidosis

Sarcoidosis is an inflammatory multisystemic granulomatosis of unknown cause, with a wide range of clinical features, characterized by the presence of non-caseating granulomas. Liver is the third involved organ after lungs and lymph nodes, with a …

Anti-TIF1-beta autoantibody-positive dermatomyositis: a case-based review

To describe the clinical features and cancer risk in patients with dermatomyositis (DM) and anti-TIF1β autoantibodies without other DM-specific autoantibodies (anti-TIF1β-monospecific DM) through a case-based review. Case report of …

Elevate your expertise in aplastic anemia (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME
Learn more

CME & eLearning

eLearning (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME

Further Reading

Evaluation of Real-World Treatment Patterns and Healthcare Resource Utilization in Patients with Chronic Refractory Gout in the United States

  • Open Access
  • Gout
  • Original Research

Gout is a common form of inflammatory arthritis caused by elevated levels of serum urate (hyperuricemia) [ 1 ]. The prevalence of gout among adults in the United States (US) is estimated at 3.9%, corresponding to approximately 9.2 million affected …

In-Person and Virtual Clinic Visit Frequency to Rheumatologists for Rheumatoid Arthritis at an Academic Medical Center Before, During, and After COVID Lockdown

The COVID-19 pandemic caused major disruptions to care delivery. Many physicians’ offices were closed for several months, and virtual care dominated. Visit volumes initially plummeted [ 1 ]. These changes have been well documented in primary care …

Associations between comorbidities and patient-reported outcomes in axial spondyloarthritis: data from a single-center real-world cohort

Spondyloarthritis (SpA) refers to a group of chronic inflammatory diseases of unknown origin with shared pathophysiological and clinical features, primarily affecting the musculoskeletal system (e.g., spine, joints, entheses, and ligaments) [ 1 , 2 …]. Axial SpA (axSpA) is characterized by predominant involvement of the sacroiliac joints and spine. It encompasses two main classifications: ankylosing spondylitis (AS), which fulfils the radiographic Modified New York criteria [

Health-related quality of life among patients with rheumatoid arthritis in Zanzibar: a prospective cohort study

Patients with rheumatoid arthritis have poorer quality of life compared to healthy controls. Data on this in sub-Saharan Africa is sparse and few studies have used controls for comparison. In this study we aimed to assess the quality of life of …

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Lumbar sympathetic block to treat CRPS in a toddler

After non-invasive measures failed, a lumbar sympathetic block performed with extreme caution alleviated complex regional pain syndrome in this 18-month-old.

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Self-guided digital behavioral therapy for fibromyalgia

Caution needed when prescribing gabapentinoids in people with COPD

Illness uncertainty in hypermobile Ehlers-Danlos syndrome

Neurostimulation therapies for chronic pain

How to approach statin therapy in vulnerable groups

Statins can be key to preventing ASCVD but remain underused in vulnerable populations, such as those with CKD, MASLD, HIV, lupus and other immune-associated inflammatory conditions. What should be considered when treating these groups?

Read more

Association of IgA vasculitis with rare leukemia

Izokibep shows potential for psoriatic arthritis

IL-17A inhibition in rheumatic and musculoskeletal diseases

Novel association of chilblains with inflammatory arthritis

Study supports first-line biologics for Still disease

Trial supports metformin use in osteoarthritis

Treatment with the diabetes medication metformin significantly reduces knee pain in patients with symptomatic knee osteoarthritis who have overweight or obesity.

Read more

Osteoporosis and osteoarthritis in elderly patients

Biomarkers in hand osteoarthritis

Use of platelet-rich plasma in rheumatic diseases

Are heated mittens useful in osteoarthritis?

Better pain relief with total hip replacement for hip osteoarthritis

Ulcerative cutaneous sarcoidosis: a diagnostic challenge

Diagnosing cutaneous sarcoidosis can be challenging due to its diverse skin manifestations, which can mimic other conditions. In this case, the patient presented with chronic leg ulcers.

Read more

ALS in a patient with CLL and drug-related SLR

Cardio-rheumatology: an emerging specialty

Corticosteroids for hydrocephalus in neurosarcoidosis

Complications from conduction system pacing

Concurrent sarcoidosis and hypersensitivity pneumonitis

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