A proof-of-concept study suggests that treatment with the JAK inhibitor tofacitinib could increase skeletal muscle mass in patients with rheumatoid arthritis.
Another case report contributing to the growing body of literature on gastrointestinal involvement in systemic lupus erythematosus, and underscoring the importance of early recognition and targeted treatment.
Explore recent progress in clinical and molecular endotyping of primary Sjögren disease, and understand how these insights can inform the development of precision treat-to-target strategies.
A young man with antiphospholipid syndrome presented with left main coronary artery STEMI. Through a novel strategy combining drug-coated balloon angioplasty and anticoagulation and immunomodulation therapy, the patient displayed sustained patency without recurrent thrombosis at one year follow up.
Systemic lupus erythematosus is a severe autoimmune disease that can cause damage to almost every system of the body. Learn more about novel biomarkers for diagnosis and monitoring, and familiarize yourself with current and emerging targeted therapies.
Another case report contributing to the growing body of literature on gastrointestinal involvement in systemic lupus erythematosus, and underscoring the importance of early recognition and targeted treatment.
A young man with antiphospholipid syndrome presented with left main coronary artery STEMI. Through a novel strategy combining drug-coated balloon angioplasty and anticoagulation and immunomodulation therapy, the patient displayed sustained patency without recurrent thrombosis at one year follow up.
Patient presented with axial proptosis, conjunctival congestion, chemosis, and a small corneal perforation with iris prolapse and flat anterior chamber. Systemic investigations led to diagnosis of granulomatosis with polyangiitis, requiring antibiotics, steroids and bandage contact lens application.
Why are disease-modifying treatments for osteoarthritis such a difficult proposition?
Despite multiple attempts, no DMOAD is yet approved for clinical use. Prof. Ali Mobasheri takes us through the main challenges, the work being done to make these so-called utopia drugs a reality, and discusses other advances that offer hope in the meantime.
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic syndrome) is an adult-onset autoinflammatory disorder caused by somatic mutations in the UBA1 gene. While its clinical spectrum is expanding, the overlap with autoimmune diseases …
Rheumatoid arthritis (RA), an autoimmune disease characterized by chronic, symmetric, and erosive polyarthritis, can lead to joint destruction, deformity, and functional impairment. In its early stages, radiographic imaging typically reveals …
Compared to non-surgical management, vertebral augmentation offers faster pain relief, faster functional mobility, and lower morbidity/mortality (level of evidence: high) Vertebral augmentation should be performed 3–6 weeks after the fracture event …
Temporomandibular disorders (TMDs) constitute a diverse group of musculoskeletal and neuromuscular conditions affecting the temporomandibular joint (TMJ), masticatory muscles, and associated anatomical structures [ 1 ]. These disorders are …
Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases.
Transform the way you care for your patients with aplastic anemia with our 3-module eLearning series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases.
This qualitative study enriched the understanding of patient attitudes towards parenteral methotrexate by employing the Theoretical Framework of Acceptability and addressing gaps in the literature. High patient acceptance of parenteral methotrexate …
Psoriatic arthritis (PsA) is a heterogeneous and complex inflammatory disease associated with a significant clinical burden, since it presents heterogeneous manifestations including cutaneous (psoriasis of skin and nails), musculoskeletal …
Osteoarthritis (OA) is a long-term chronic disease characterized by the deterioration of cartilage in joints. It is often thought of as a degenerative condition, but it does not arise only because of gradual wear and tear. Instead, it should be …
Psoriatic arthritis (PsA) is a systemic, chronic inflammatory disease typically characterized by musculoskeletal and dermal symptoms [ 1 ]. The musculoskeletal symptom domain includes peripheral arthritis, axial disease, enthesitis, and dactylitis …
In a large database analysis, use of GLP-1 receptor agonists was associated with a reduced symptom burden in people with fibromyalgia, but further studies with validated outcome measures are needed.
A proof-of-concept study suggests that treatment with the JAK inhibitor tofacitinib could increase skeletal muscle mass in patients with rheumatoid arthritis.
Understand the significance of vitamin D for bone health, especially its mechanism of action and clinical significance in bone destruction diseases such as osteoarthritis, osteoporosis, rheumatoid arthritis, and bone tuberculosis.
Adding a conventional synthetic disease-modifying antirheumatic drug to first-line systemic corticosteroid therapy may reduce treatment failure in patients with nonanterior sarcoidosis-associated uveitis.
