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Internal Medicine Rheumatology

Rheumatology

Diabetic foot in the context of rheumatic diseases

Understand the pathogenic mechanisms underlying diabetic foot development in patients with rheumatic diseases, the impact of chronic inflammation and drug therapy, and current diagnostic approaches, treatment strategies, and preventive measures.

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Editor's Choice

Ulcerative cutaneous sarcoidosis: a diagnostic challenge

Diagnosing cutaneous sarcoidosis can be challenging due to its diverse skin manifestations, which can mimic other conditions. In this case, the patient presented with chronic leg ulcers.

Trial supports metformin use in osteoarthritis

Treatment with the diabetes medication metformin significantly reduces knee pain in patients with symptomatic knee osteoarthritis who have overweight or obesity.

How to approach statin therapy in vulnerable groups

Statins can be key to preventing ASCVD but remain underused in vulnerable populations, such as those with CKD, MASLD, HIV, lupus and other immune-associated inflammatory conditions. What should be considered when treating these groups?

Association of IgA vasculitis with rare leukemia

This first report of IgA vasculitis associated with chronic myelomonocytic leukemia highlights the need for awareness of underlying hematologic malignancies in patients presenting with unexplained vasculitis.

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Episode 17: Challenges of developing DMOADs

Why are disease-modifying treatments for osteoarthritis such a difficult proposition?

Despite multiple attempts, no DMOAD is yet approved for clinical use. Prof. Ali Mobasheri takes us through the main challenges, the work being done to make these so-called utopia drugs a reality, and discusses other advances that offer hope in the meantime.

Prof. Ali Mobasheri
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Podcast

Latest News

Trial supports metformin use in osteoarthritis

Izokibep shows potential for psoriatic arthritis

Study supports first-line biologics for Still disease

Upadacitinib may offer a glucocorticoid-sparing option for GCA

Reduced infection risk with IL-targeting biologics

Pros and cons of glucocorticoid cessation

Case Studies

Ulcerative cutaneous sarcoidosis: a diagnostic challenge

Diagnosing cutaneous sarcoidosis can be challenging due to its diverse skin manifestations, which can mimic other conditions. In this case, the patient presented with chronic leg ulcers.

Association of IgA vasculitis with rare leukemia

This first report of IgA vasculitis associated with chronic myelomonocytic leukemia highlights the need for awareness of underlying hematologic malignancies in patients presenting with unexplained vasculitis.

Novel association of chilblains with inflammatory arthritis

Three patients with inflammatory arthritis had concomitant chilblains and bone marrow edema as revealed by MRI. Could this trifecta represent a new clinical phenotype of seronegative spondyloarthropathies?

Keynote webinar | Spotlight on advances in lupus

  • Live
  • Webinar | 27-05-2025 | 18:00 (CEST)

Systemic lupus erythematosus is a severe autoimmune disease that can cause damage to almost every system of the body. Join this session to learn more about novel biomarkers for diagnosis and monitoring and familiarise yourself with current and emerging targeted therapies.

Join us live: Tuesday 27th May, 18:00-19:15 (CEST)

Prof. Edward Vital
Prof. Ronald F. van Vollenhoven
Developed by: Springer Medicine
Register now
Webinar

Current Reviews

Navigating Psoriatic Arthritis: Treatment Pathways and Patient-Specific Strategies for Improved Outcomes

Psoriatic arthritis (PsA) is a multifaceted chronic immune-mediated disease characterized by joint, skin, nail and entheseal involvement, affecting approximately 0.3–1% of the global population. In recent years, the treatment options for PsA have …

Prevention of rheumatoid arthritis is challenging, but early intervention in at-risk individuals shows promise

Rheumatoid arthritis (RA) development begins with the preclinical phase that can progress to clinical RA. It is hypothesised that the prevention of RA in at-risk individuals may be possible with interventions targeting the preclinical phase.

History of anterior cruciate ligament reconstruction does not increase the risk of postoperative complications following total knee arthroplasty: a systematic review and meta-analysis

Osteoarthritis (OA) is a chronic degenerative disease characterized by the degeneration of articular cartilage and pathological changes of subchondral bone, affecting over 500 million individuals worldwide [ 1 ]. OA has a high incidence and …

Imaging in clinical trials of axial spondyloarthritis: what type of imaging should be used

Axial spondyloarthritis (axSpA) is a chronic inflammatory condition predominantly affecting the sacroiliac joints and spine. Early and accurate diagnosis is crucial to prevent structural damage and improve patient outcomes. Imaging plays a pivotal …

Elevate your expertise in aplastic anemia (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME
Learn more

CME & eLearning

eLearning (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME

Further Reading

Healthcare Professionals’ Experiences with Vocational Rehabilitation for People with Inflammatory Arthritis

In Denmark, approximately 50,000 are diagnosed with rheumatoid arthritis and 30,000 with psoriatic arthritis or axial spondyloarthritis [ 1 ]. In this paper, these diagnoses are referred to as chronic inflammatory arthritis (IA). Despite the …

Oncogenic rickets diagnosed at age 8 and the risk of persistent rickets: a rare case of pediatric-onset tumor-induced osteomalacia

Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by excess fibroblast growth factor 23 (FGF23), leading to hypophosphatemia and osteomalacia. It typically manifests in adulthood, with pediatric cases being exceedingly …

Dapagliflozin targets the crosstalk between apoptosis, autophagy, and Hedgehog signaling pathways through AMPK activation in the adjuvant-induced arthritic rat model

Rheumatoid arthritis is a long-term autoimmune disorder, causes joint capsule, cartilage, and bone damage. Dapagliflozin, a novel antidiabetic drug, demonstrated promising effects against different disorders. Herein, we aimed to detect the …

Navigating Psoriatic Arthritis: Treatment Pathways and Patient-Specific Strategies for Improved Outcomes

Psoriatic arthritis (PsA) is a multifaceted chronic immune-mediated disease characterized by joint, skin, nail and entheseal involvement, affecting approximately 0.3–1% of the global population. In recent years, the treatment options for PsA have …

Related topics

Lumbar sympathetic block to treat CRPS in a toddler

After non-invasive measures failed, a lumbar sympathetic block performed with extreme caution alleviated complex regional pain syndrome in this 18-month-old.

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Self-guided digital behavioral therapy for fibromyalgia

Caution needed when prescribing gabapentinoids in people with COPD

Illness uncertainty in hypermobile Ehlers-Danlos syndrome

Neurostimulation therapies for chronic pain

Diabetic foot in the context of rheumatic diseases

Understand the pathogenic mechanisms underlying diabetic foot development in patients with rheumatic diseases, the impact of chronic inflammation and drug therapy, and current diagnostic approaches, treatment strategies, and preventive measures.

Read more

How to approach statin therapy in vulnerable groups

Association of IgA vasculitis with rare leukemia

Izokibep shows potential for psoriatic arthritis

IL-17A inhibition in rheumatic and musculoskeletal diseases

Novel association of chilblains with inflammatory arthritis

Trial supports metformin use in osteoarthritis

Treatment with the diabetes medication metformin significantly reduces knee pain in patients with symptomatic knee osteoarthritis who have overweight or obesity.

Read more

Osteoporosis and osteoarthritis in elderly patients

Biomarkers in hand osteoarthritis

Use of platelet-rich plasma in rheumatic diseases

Are heated mittens useful in osteoarthritis?

Better pain relief with total hip replacement for hip osteoarthritis

Ulcerative cutaneous sarcoidosis: a diagnostic challenge

Diagnosing cutaneous sarcoidosis can be challenging due to its diverse skin manifestations, which can mimic other conditions. In this case, the patient presented with chronic leg ulcers.

Read more

ALS in a patient with CLL and drug-related SLR

Cardio-rheumatology: an emerging specialty

Corticosteroids for hydrocephalus in neurosarcoidosis

Complications from conduction system pacing

Concurrent sarcoidosis and hypersensitivity pneumonitis

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