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Internal Medicine Rheumatology

Rheumatology

Possible CV benefit of TNF inhibitors in inflammatory arthritis?

Accumulating evidence suggests that inflammation could explain the increased cardiovascular risk in patients with immune-mediated arthritis. Could TNF inhibitors, which suppress inflammation, perhaps reduce this risk?

Read more

Editor's Choice

Ixekizumab slows bone damage in axial spondyloarthritis

Treatment with ixekizumab rapidly reduces sacroiliac joint erosion and promotes backfill in patients with radiographic axial spondyloarthritis.

GCA a potential cause of aseptic meningitis?

A patient diagnosed with aseptic meningitis developed a right temporal headache with scalp tenderness, and imaging results were consistent with giant cell arteritis. Could the GCA have caused the aseptic meningitis?

microRNAs in the management of obesity and osteoporosis

miRNAs have a key role in regulating the balance between adipogenesis and osteogenesis. Could miRNA-based interventions address the altered bone metabolism and adipose tissue dynamics in obesity and osteoporosis?

Acute pancreatitis as presenting feature of SLE

Gastrointestinal involvement is common in systemic lupus erythematosus but acute pancreatitis as an initial manifestation is extremely rare. The patient's abdominal symptoms resolved after corticosteroid and cyclophosphamide therapy.

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Elevate your expertise in aplastic anemia (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME
Learn more

Latest News

Ixekizumab slows bone damage in axial spondyloarthritis

Minimum 3 years remission crucial for preserving renal function in LN

FMT fails to ReSScue GI symptoms in systemic sclerosis patients

Add-on obinutuzumab improves response in lupus nephritis

Can TNF inhibitors be used in RA patients with cancer?

High rate of relapse after adalimumab discontinuation in JIA

Case Studies

GCA a potential cause of aseptic meningitis?

A patient diagnosed with aseptic meningitis developed a right temporal headache with scalp tenderness, and imaging results were consistent with giant cell arteritis. Could the GCA have caused the aseptic meningitis?

Acute pancreatitis as presenting feature of SLE

Gastrointestinal involvement is common in systemic lupus erythematosus but acute pancreatitis as an initial manifestation is extremely rare. The patient's abdominal symptoms resolved after corticosteroid and cyclophosphamide therapy.

Uncommon type of vasculitis

Isolated celiac artery vasculitis is extremely rare, but it should be considered in the differential diagnosis of unexplained abdominal pain, particularly when imaging reveals vascular abnormalities.

Current Reviews

Sex Differences in Obesity and Its Treatment

In the past three decades, the prevalence of obesity in adults increased in almost every country among both females and males [ 1 ]. During this time, the age-standardized prevalence of obesity rose by more than 20% points in 49 countries (25% of …

Prediction models for adjacent vertebral fractures after vertebral augmentation: a systematic review and meta-analysis

Osteoporosis is a prevalent degenerative skeletal disease in the elderly, characterized by reduced bone mass, increased bone fragility, deterioration of bone structure, and a heightened risk of fractures [ 1 , 2 ], with a global prevalence of 18.3% …

Safety of Anti-osteoarthritis Medications: A Systematic Literature Review of Post-marketing Surveillance Studies

Osteoarthritis (OA) is the most common joint disease and a major public health issue, particularly in the context of global population growth and ageing, representing a significant burden for patients, societies and healthcare systems [ 1 – 3 ]. In …

Impact of Disease-Modifying Antirheumatic Drugs on Cognitive Function in Older Adults with Rheumatoid Arthritis

Cognitive impairment poses significant challenges for aging populations. Systemic inflammation, a hallmark of rheumatoid arthritis (RA), has been implicated in neurodegeneration through mechanisms including blood–brain barrier disruption …

CME & eLearning

eLearning (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME

Further Reading

The ultrasonographic spectrum of toe dactylitis in psoriatic arthritis: a descriptive analysis

Dactylitis, the uniform swelling of a hand or foot finger related to the simultaneous inflammatory involvement of all the articular and periarticular structures, is a clinical feature of spondyloenthesoarthritis. This manifestation is particularly …

Healthcare and productivity cost of osteoporosis: a Danish register-based quasi-experimental study

Osteoporosis is a chronic progressive disease that is associated with low bone mineral density (BMD) resulting in weakened and fragile bones [ 1 ], which increases susceptibility to bone fractures [ 2 ].

An Up-to-Date Description of the Use of Non-steroidal Anti-inflammatory Drugs (NSAIDs) in Italy: Evidence from Real Clinical Practice

Pain is a common symptom reported by patients in both medical and surgical settings [ 1 , 2 ]. Given the multidimensional and subjective nature of pain, together with the large variability in response to medications, many prescribers are guided in …

Granulomatous nephropathy: have you thought about genetics?

We report here the case of a 16-year-old girl with chronic kidney disease, where biopsy revealed tubulointerstitial nephropathy with granulomas. Initial treatments included immunosuppressive therapy unless genetic testing with exome sequencing …

Related topics

Lumbar sympathetic block to treat CRPS in a toddler

After non-invasive measures failed, a lumbar sympathetic block performed with extreme caution alleviated complex regional pain syndrome in this 18-month-old.

Read more

Self-guided digital behavioral therapy for fibromyalgia

Caution needed when prescribing gabapentinoids in people with COPD

Illness uncertainty in hypermobile Ehlers-Danlos syndrome

Neurostimulation therapies for chronic pain

Possible CV benefit of TNF inhibitors in inflammatory arthritis?

Accumulating evidence suggests that inflammation could explain the increased cardiovascular risk in patients with immune-mediated arthritis. Could TNF inhibitors, which suppress inflammation, perhaps reduce this risk?

Read more

Ixekizumab slows bone damage in axial spondyloarthritis

GCA a potential cause of aseptic meningitis?

Acute pancreatitis as presenting feature of SLE

Minimum 3 years remission crucial for preserving renal function in LN

Ultrasound beyond joints

Osteoporosis and osteoarthritis in elderly patients

What are the key considerations for managing osteoporosis and osteoarthritis in the oldest old (≥80 years), in the context of multimorbidity, physical and mental disability, and polypharmacy?

Read more

Biomarkers in hand osteoarthritis

Use of platelet-rich plasma in rheumatic diseases

Are heated mittens useful in osteoarthritis?

Better pain relief with total hip replacement for hip osteoarthritis

Semaglutide shows promise for obesity-related osteoarthritis

ALS in a patient with CLL and drug-related SLR

A man with a skin rash and left leg weakness was diagnosed with sarcoid-like reaction due to treatment for chronic lymphocytic leukemia, and ultimately also amyotrophic lateral sclerosis when the motor symptoms progressed.

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Cardio-rheumatology: an emerging specialty

Corticosteroids for hydrocephalus in neurosarcoidosis

Complications from conduction system pacing

Concurrent sarcoidosis and hypersensitivity pneumonitis

Current applications of AI in sarcoidosis

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