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Internal Medicine Rheumatology

Rheumatology

DMARDs boost treatment success in nonanterior sarcoidosis-associated uveitis

Adding a conventional synthetic disease-modifying antirheumatic drug to first-line systemic corticosteroid therapy may reduce treatment failure in patients with nonanterior sarcoidosis-associated uveitis.

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Editor's Choice

SSc tied to increased cardiovascular, thromboembolic risk

Patients with systemic sclerosis have an increased risk for cardiovascular disease and venous thromboembolism before and after diagnosis.

Rheumatoid arthritis and family planning

Equip yourself to counsel your patients with rheumatoid arthritis about reproductive health concerns, such as contraception safety, infertility, and the management of RA medications during pregnancy and breastfeeding.

Kidney involvement in VEXAS syndrome

VEXAS syndrome is a recently identified genetic autoinflammatory disorder. This case highlights its under-recognized renal manifestations and underscores the need for heightened clinical suspicion and earlier intervention.

Physical activity linked to reduced SLE risk

Engaging in moderate or high physical activity may significantly reduce the risk for developing systemic lupus erythematosus, independent of sociodemographic, lifestyle, and environmental factors.

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Keynote webinar | Spotlight on advances in lupus

  • Webinar | 27-05-2025 | 17:00 (CEST)

On-demand video coming soon

Systemic lupus erythematosus is a severe autoimmune disease that can cause damage to almost every system of the body. Join this session to learn more about novel biomarkers for diagnosis and monitoring and familiarise yourself with current and emerging targeted therapies.

Prof. Edward Vital
Prof. Ronald F. van Vollenhoven
Developed by: Springer Medicine
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Latest News

DMARDs boost treatment success in nonanterior sarcoidosis-associated uveitis

SSc tied to increased cardiovascular, thromboembolic risk

Physical activity linked to reduced SLE risk

SSc-associated ILD progression may not signal future decline

Anifrolumab improves long-term quality of life in lupus

Novel toxicity of CAR T-cell therapy in autoimmune disease

Case Studies

Kidney involvement in VEXAS syndrome

VEXAS syndrome is a recently identified genetic autoinflammatory disorder. This case highlights its under-recognized renal manifestations and underscores the need for heightened clinical suspicion and earlier intervention.

Takayasu arteritis complicated by SAPHO syndrome

Two patients presenting with anterior chest pain were diagnosed with Takayasu arteritis co-existing with SAPHO syndrome, a rare inflammatory osteoarticular disorder. Their symptoms improved with glucocorticoids and biologic agents.

Atypical manifestation of giant cell arteritis

The presence of a non-healing tongue ulcer indicated end-organ damage from GCA and prompted suspicion of the condition even in the absence of imaging or biopsy evidence. The patient responded to treatment, confirming the diagnosis.

Episode 17: Challenges of developing DMOADs

Why are disease-modifying treatments for osteoarthritis such a difficult proposition?

Despite multiple attempts, no DMOAD is yet approved for clinical use. Prof. Ali Mobasheri takes us through the main challenges, the work being done to make these so-called utopia drugs a reality, and discusses other advances that offer hope in the meantime.

Prof. Ali Mobasheri
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Podcast

Current Reviews

Allogeneic hematopoietic cell transplantation for autoinflammatory disorders

The understanding of autoinflammatory disorders, which are caused by the dysregulated activation of the innate immune system, has improved with the discovery of new diseases and the expansion of phenotypes. Inflammation can be controlled using …

Progress on the mechanism of natural polysaccharides in the treatment of arthritis

Arthritis is a common joint-injury disease, and because its exact etiology and pathogenesis remain incompletely understood, current treatment options for it are highly limited. Conventional treatments focus on anti-inflammatory drugs to alleviate …

Use of DCE-MRI in arthritis in the appendicular skeleton: a narrative review

Arthritis of the appendicular skeleton encompasses various inflammatory and degenerative joint diseases, where active inflammation in the soft tissues and bones significantly affects patients’ quality of life and prognosis. Therefore, effective …

Machine learning is changing osteoporosis detection: an integrative review

Osteoporosis is a metabolic bone disease characterized by decreased bone density and damage to bone microstructure, leading to increased bone fragility and a significantly elevated risk of fracture. Since early symptoms of osteoporosis are not …

Elevate your expertise in aplastic anemia (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Health+ IME
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CME & eLearning

eLearning (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Health+ IME

Further Reading

Patient-Reported Outcomes by Baseline Body Surface Area Involvement Among Individuals Initiating Biologic Therapy: Results from the CorEvitas Psoriasis Registry

Psoriasis is a chronic, immune-mediated, inflammatory disease that affects approximately 3% of the US adult population [ 1 ]. The disease burden of psoriasis can vary according to factors including anatomical location of plaques (e.g., face, scalp …

Allogeneic hematopoietic cell transplantation for autoinflammatory disorders

The understanding of autoinflammatory disorders, which are caused by the dysregulated activation of the innate immune system, has improved with the discovery of new diseases and the expansion of phenotypes. Inflammation can be controlled using …

Clinical, radiologic, and serologic predictors of rheumatic disease in interstitial lung disease patients

Interstitial lung disease (ILD) is associated with significant morbidity and mortality among patients with systemic rheumatic diseases including rheumatoid arthritis (RA), systemic sclerosis (SSc), primary Sjögren’s syndrome (pSS), idiopathic …

LncRNA PVT1 regulates CD4 + T cell dysregulation in systemic lupus erythematosus: insights from human patients and MRL/lpr mouse

Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease that may cause chronic inflammation and debilitating damage in multiple organs and tissues [ 1 ]. It is characterized by a global breakdown of immune tolerance with activation …

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DMARDs boost treatment success in nonanterior sarcoidosis-associated uveitis

Adding a conventional synthetic disease-modifying antirheumatic drug to first-line systemic corticosteroid therapy may reduce treatment failure in patients with nonanterior sarcoidosis-associated uveitis.

Read more

SSc tied to increased cardiovascular, thromboembolic risk

Rheumatoid arthritis and family planning

Kidney involvement in VEXAS syndrome

Physical activity linked to reduced SLE risk

Precision over prednisone: innovation in GCA treatment

Heterotopic ossification after wrist replacement

The first reported case of heterotopic ossification following total wrist arthroplasty. Revision surgery was performed to remove ossifications and no further signs have been reported, but the patient's range of motion remains reduced.

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Trial supports metformin use in osteoarthritis

Osteoporosis and osteoarthritis in elderly patients

Biomarkers in hand osteoarthritis

Use of platelet-rich plasma in rheumatic diseases

Are heated mittens useful in osteoarthritis?

DMARDs boost treatment success in nonanterior sarcoidosis-associated uveitis

Adding a conventional synthetic disease-modifying antirheumatic drug to first-line systemic corticosteroid therapy may reduce treatment failure in patients with nonanterior sarcoidosis-associated uveitis.

Read more

Ulcerative cutaneous sarcoidosis: a diagnostic challenge

ALS in a patient with CLL and drug-related SLR

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Corticosteroids for hydrocephalus in neurosarcoidosis

Complications from conduction system pacing

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