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Internal Medicine Rheumatology

Rheumatology

Heterotopic ossification after wrist replacement

The first reported case of heterotopic ossification following total wrist arthroplasty. Revision surgery was performed to remove ossifications and no further signs have been reported, but the patient's range of motion remains reduced.

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Editor's Choice

Successful treatment of stroke due to Takayasu arteritis

Mechanical thrombectomy and stenting were used to manage large vessel occlusion stroke in a patient with Takayasu arteritis, without any short- or long-term complications. This approach could be an effective option in these patients.

Novel toxicity of CAR T-cell therapy in autoimmune disease

CAR T-cell therapy has been linked to a potentially new toxicity syndrome in people with autoimmune disease by German researchers.

Diabetic foot in the context of rheumatic diseases

Understand the pathogenic mechanisms underlying diabetic foot development in patients with rheumatic diseases, the impact of chronic inflammation and drug therapy, and current diagnostic approaches, treatment strategies, and preventive measures.

Ulcerative cutaneous sarcoidosis: a diagnostic challenge

Diagnosing cutaneous sarcoidosis can be challenging due to its diverse skin manifestations, which can mimic other conditions. In this case, the patient presented with chronic leg ulcers.

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Episode 17: Challenges of developing DMOADs

Why are disease-modifying treatments for osteoarthritis such a difficult proposition?

Despite multiple attempts, no DMOAD is yet approved for clinical use. Prof. Ali Mobasheri takes us through the main challenges, the work being done to make these so-called utopia drugs a reality, and discusses other advances that offer hope in the meantime.

Prof. Ali Mobasheri
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Podcast

Latest News

Novel toxicity of CAR T-cell therapy in autoimmune disease

Trial supports metformin use in osteoarthritis

Izokibep shows potential for psoriatic arthritis

Study supports first-line biologics for Still disease

Upadacitinib may offer a glucocorticoid-sparing option for GCA

Reduced infection risk with IL-targeting biologics

Case Studies

Heterotopic ossification after wrist replacement

The first reported case of heterotopic ossification following total wrist arthroplasty. Revision surgery was performed to remove ossifications and no further signs have been reported, but the patient's range of motion remains reduced.

Successful treatment of stroke due to Takayasu arteritis

Mechanical thrombectomy and stenting were used to manage large vessel occlusion stroke in a patient with Takayasu arteritis, without any short- or long-term complications. This approach could be an effective option in these patients.

Ulcerative cutaneous sarcoidosis: a diagnostic challenge

Diagnosing cutaneous sarcoidosis can be challenging due to its diverse skin manifestations, which can mimic other conditions. In this case, the patient presented with chronic leg ulcers.

Keynote webinar | Spotlight on advances in lupus

  • Live
  • Webinar | 27-05-2025 | 18:00 (CEST)

Systemic lupus erythematosus is a severe autoimmune disease that can cause damage to almost every system of the body. Join this session to learn more about novel biomarkers for diagnosis and monitoring and familiarise yourself with current and emerging targeted therapies.

Join us live: Tuesday 27th May, 18:00-19:15 (CEST)

Prof. Edward Vital
Prof. Ronald F. van Vollenhoven
Developed by: Springer Medicine
Register now
Webinar

Current Reviews

Endoscopic management of lumbar spinal tophaceous gout: six cases treated with percutaneous transforaminal (PTED) and interlaminar (PIED) discectomy and a literature review

Gout is a metabolic disease characterized by the deposition of monosodium urate (MSU) crystals in various joints throughout the body, triggering local inflammatory responses and tissue destruction. Gout typically affects the peripheral joints …

Review of pulmonary manifestations of rheumatoid arthritis

Rheumatoid arthritis (RA) is a systemic autoinflammatory disorder that primarily affects joints. However, RA can involve extra-articular structures as well, including the lungs, affecting significant morbidity and mortality, though the precise …

The Effects of GLP-1 Agonists on Musculoskeletal Health and Orthopedic Care

The global surge in obesity and type 2 diabetes mellitus (T2DM) presents significant challenges in orthopedic care, directly impacting musculoskeletal health and surgical outcomes. These metabolic disorders are associated with increased rates of …

Navigating Psoriatic Arthritis: Treatment Pathways and Patient-Specific Strategies for Improved Outcomes

Psoriatic arthritis (PsA) is a multifaceted chronic immune-mediated disease characterized by joint, skin, nail and entheseal involvement, affecting approximately 0.3–1% of the global population. In recent years, the treatment options for PsA have …

Elevate your expertise in aplastic anemia (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME
Learn more

CME & eLearning

eLearning (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME

Further Reading

Cervical Mycobacterium genavense infection in a patient with lymphadenitis and previously unknown anti-IFN-γ IgG autoantibodies

Mycobacterium genavense is an opportunistic nontuberculous mycobacterium with a tropism for the intestinal tract first described in 1992 [ 3 ]. Initially known for life-threatening infections in people living with HIV, associations with other …

Influence of Rheumatoid Factors on the Efficacy of TNF Inhibitor Therapy in Patients with Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a representative autoimmune disease primarily characterized by synovitis. The clinical symptoms of RA include joint pain, swelling, morning stiffness, pyrexia, and malaise. Additionally, patients with RA may develop …

Clinical study evaluating the efficacy and safety of Cilostazol as an adjuvant therapy to methotrexate on patients with rheumatoid arthritis

Rheumatoid arthritis (RA) is an immune-mediated disorder marked by ongoing joint inflammation and articular destruction (Edilova et al. 2021 ). Tumor necrosis factor-α (TNF-α) and interleukin-1 beta (IL-1β), which are derived from phagocytes, are …

Prevalence and clinical relevance of digital ulcers in systemic sclerosis patients from the real-life: the experience of the SPRING Registry of the Italian Society for Rheumatology

Digital ulcers (DU) are one of the most frequent manifestations in systemic sclerosis (SSc) [ 1 – 3 ], affecting around 58% of SSc patients [ 4 ], also in the very early phase of the disease [ 5 ]. Scleroderma vascular manifestations characterize …

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Lumbar sympathetic block to treat CRPS in a toddler

After non-invasive measures failed, a lumbar sympathetic block performed with extreme caution alleviated complex regional pain syndrome in this 18-month-old.

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Self-guided digital behavioral therapy for fibromyalgia

Caution needed when prescribing gabapentinoids in people with COPD

Illness uncertainty in hypermobile Ehlers-Danlos syndrome

Neurostimulation therapies for chronic pain

Successful treatment of stroke due to Takayasu arteritis

Mechanical thrombectomy and stenting were used to manage large vessel occlusion stroke in a patient with Takayasu arteritis, without any short- or long-term complications. This approach could be an effective option in these patients.

Read more

Novel toxicity of CAR T-cell therapy in autoimmune disease

Diabetic foot in the context of rheumatic diseases

How to approach statin therapy in vulnerable groups

Association of IgA vasculitis with rare leukemia

Izokibep shows potential for psoriatic arthritis

Heterotopic ossification after wrist replacement

The first reported case of heterotopic ossification following total wrist arthroplasty. Revision surgery was performed to remove ossifications and no further signs have been reported, but the patient's range of motion remains reduced.

Read more

Trial supports metformin use in osteoarthritis

Osteoporosis and osteoarthritis in elderly patients

Biomarkers in hand osteoarthritis

Use of platelet-rich plasma in rheumatic diseases

Are heated mittens useful in osteoarthritis?

Ulcerative cutaneous sarcoidosis: a diagnostic challenge

Diagnosing cutaneous sarcoidosis can be challenging due to its diverse skin manifestations, which can mimic other conditions. In this case, the patient presented with chronic leg ulcers.

Read more

ALS in a patient with CLL and drug-related SLR

Cardio-rheumatology: an emerging specialty

Corticosteroids for hydrocephalus in neurosarcoidosis

Complications from conduction system pacing

Concurrent sarcoidosis and hypersensitivity pneumonitis

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