Skip to main content

Respiratory Medicine

Case Studies

Cryptogenic stroke associated with pulmonary arteriovenous fistula

  • Open Access
  • Stroke
  • Case Study

In this unusual case, OCT revealed multiple mural thrombi in a PAVF as the source of embolic strokes and continuing ischemic attacks, indicating a potential emboligenic mechanism in PAVF.

Tuberculosis of the elbow joint

Elbow tuberculosis is a rare manifestation of TB, with symptoms often mimicking diseases such as rheumatoid or septic arthritis. Surgical intervention can greatly benefit diagnosis, but is not always necessary for successful treatment.

Rare presentation of ocular tuberculosis

Mycobacterium TB can infect any ophthalmic tissue. Most common ocular presentations are granulomatous anterior uveitis and posterior uveitis, but this case shows rare bilateral corneoscleral perforation.

Successful treatment of juvenile dermatomyositis

The JAK inhibitor tofacitinib proved effective in treating a 7-year-old with anti-MDA5 antibody-positive juvenile dermatomyositis complicated by refractory interstitial lung disease.

Synchronous breast cancer and pleural mesothelioma

A woman who underwent mastectomy and chemotherapy for breast cancer subsequently developed chest pain and dyspnea. Would you have considered pleural mesothelioma as the cause?

An extremely rare subtype of lymphoma

Primary pulmonary DLBCL is a rare clinical condition with nonspecific clinical manifestations, posing significant challenges for diagnosis. This patient was initially misdiagnosed as having organizing pneumonia.

Postpartum thyroid storm

Thyroid storm had a fatal outcome in a woman with Graves disease who had not used her medications during pregnancy or since giving birth, highlighting the importance of medication adherence during the postpartum period.

A fatal side effect of a novel drug

Following treatment with the bispecific T-cell engager epcoritamab, a patient with relapsed DLBCL developed pleural effusion, which proved fatal despite aggressive management. Regular monitoring is crucial to identify and manage severe inflammatory reactions.

ALS in a patient with CLL and drug-related SLR

A man with a skin rash and left leg weakness was diagnosed with sarcoid-like reaction due to treatment for chronic lymphocytic leukemia, and ultimately also amyotrophic lateral sclerosis when the motor symptoms progressed.

Late-onset ICI-related pneumonitis

Pneumonitis related to ICI therapy typically occurs within the first few months of treatment, but this lung cancer patient experienced the adverse event 2.5 months after discontinuing pembrolizumab, underscoring the need for long-term vigilance.

Tracheal stenosis misdiagnosed as asthma

This case highlights that tracheal stenosis should be considered as a differential diagnosis in children presenting with the signs and symptoms of respiratory distress, particularly if the patient has a history of intubation.

Acute PDA stent occlusion in a newborn

Surgical resolution of a long tortuous patent ductus arteriosus from the undersurface of the aorta, in a newborn term infant diagnosed with Tetralogy of Fallot and pulmonary atresia.

Rare combination of congenital lung anomalies

A 3-year-old with respiratory problems since birth was found to have multiple congenital anomalies affecting the airway including a posterior laryngeal cleft, a tracheal bronchus, and a very narrow distal trachea.

Hearing loss as first symptom of pneumonia

The typical clinical manifestations of Chlamydia psittaci pneumonia are high fever, headache, myalgia, cough, and dyspnea. But this patient presented with sudden hearing loss. Would you have considered pneumonia?

Four cases of ICI-related fulminant myocarditis

Fatal outcomes in three cases, despite aggressive treatment, emphasize the poor prognosis of fulminant myocarditis related to immune checkpoint inhibitor therapy.

The hidden dangers of whooping cough

A case of rib fracture and pneumothorax in an adult patient with pertussis highlights the potential for significant musculoskeletal and pulmonary injuries due to the intense coughing associated with the infection. 

Co-existing parathyroid adenoma, thyroid carcinoma, and tuberculosis of the thyroid

A rare case of parathyroid adenoma, thyroid carcinoma, and thyroid tuberculosis in a woman with a history of hypothyroidism who developed a swelling on her neck and bone pain.

Rare pathogen and uncommon complication

The first report of pneumonia caused by the opportunistic pathogen Streptococcus salivarius. The case was further complicated by the development of spontaneous pneumomediastinum.

Atypical presentation of PJP

Typical symptoms of Pneumocystis jirovecii pneumonia include dyspnea, cough, and low-grade fever. But this patient, an allogeneic stem cell transplant recipient, presented with hypercalcemia and kidney injury.

Anaphylaxis due to gadolinium-based MR contrast medium

During a knee joint MRI test, a 5-year-old boy had a severe anaphylactic reaction 10 min after injection of the contrast medium. Such severe reactions are rare, but can be life-threatening.