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Respiratory Medicine

Editor's Choice

Sotatercept for advanced PAH lowers the clinical risk

Add-on therapy with sotatercept significantly reduces the risk for death and clinical worsening in patients with advanced pulmonary arterial hypertension at high risk of death.

Framework for decannulation in neurological patients

Decannulation is often complicated by severe dysphagia, reduced cough strength, excessive bronchial secretions, and altered airway anatomy. What diagnostic procedures and therapeutic options are crucial for rehabilitation?

Reduced infection risk with IL-targeting biologics

Biologics targeting interleukin-12, 23, and 17 are associated with a reduced risk for serious infections among older adults with psoriatic disease.

Surprise passenger as cause of severe anemia

  • Open Access
  • Anemia
  • Case Study

Blood-tinged saliva, light-headedness, difficulty speaking and a foreign body sensation in the throat were all reported by a 65-year-old man with severe anemia. The cause? Oropharyngeal leech infestation.

Digital vasculitis as rare presentation of anti-synthetase syndrome

The patient presented with digital vasculitis, rapidly evolving interstitial lung disease, sub-clinical myositis, and arthritis of the hands with no prior history of Raynaud’s phenomenon. What antibodies would you test to determine the final diagnosis?

How do built environments impact CVD?

The relationship between our built environment and heart health is complex and multifaceted. Discover how factors such as green spaces, walkability, food availability, and noise and air pollution, affect the risk of CVD.

Half-dose apixaban for cancer patients at risk for recurrent VTE

Patients requiring extended thromboprophylaxis after a first episode of cancer-related venous thromboembolism can be given a low dose of the factor X inhibitor apixaban.

Cryptogenic stroke associated with pulmonary arteriovenous fistula

  • Open Access
  • Stroke
  • Case Study

In this unusual case, OCT revealed multiple mural thrombi in a PAVF as the source of embolic strokes and continuing ischemic attacks, indicating a potential emboligenic mechanism in PAVF.

What intensivists need to know about CMV infections

Patients with overt immunosuppression are at risk of cytomegalovirus infection, which can lead to, or develop during, ICU admission. Learn more about its broad clinical presentations, risk factors, and management strategies.

Radiation-induced lung injury

What are the underlying mechanisms that cause radiation-induced lung injury, the most common adverse effect of thoracic radiotherapy? What is the prognosis and how can it be treated?

Tuberculosis of the elbow joint

Elbow tuberculosis is a rare manifestation of TB, with symptoms often mimicking diseases such as rheumatoid or septic arthritis. Surgical intervention can greatly benefit diagnosis, but is not always necessary for successful treatment.

Should we think twice when prescribing PPIs?

Proton pump inhibitors are a common and effective treatment for acid-related disorders, but reported adverse effects demand consideration.

IFIs in the ICU: what to consider in liver disease patients

Patients with liver disease are particularly susceptible to invasive fungal infections. Discover how hepatic dysfunction impacts systemic antifungal defenses, and what considerations should be made in ICUs.

Optimizing nutrition in children with cystic fibrosis

Malnutrition is common in children with cystic fibrosis, and it contributes to both poor pulmonary and overall disease outcomes. But what are the challenges when trying to optimize nutrition?

Reduced-dose DOACs may be an option for recurrent VTE

Reduced doses of DOACs are not noninferior to full doses in patients at high risk for recurrent VTE, but results suggest low rates overall and improved safety.

Sleep health important after gestational diabetes

Shorter sleep duration and both regular and occasional snoring are linked to an increased risk for type 2 diabetes in women with a history of gestational diabetes.

Lung ultrasound to manage neonatal respiratory distress: guidelines

Consensus recommendations from an international panel of experts on the use of lung ultrasound to optimize the management of neonatal respiratory distress.

Rare presentation of ocular tuberculosis

Mycobacterium TB can infect any ophthalmic tissue. Most common ocular presentations are granulomatous anterior uveitis and posterior uveitis, but this case shows rare bilateral corneoscleral perforation.

Ultrasound beyond joints

A practical guide to the main pathologic ultrasound findings associated with extra-articular manifestations of rheumatic diseases. Also learn about the advantages and limitations of ultrasound, and emerging innovations in the field.

Concerning increase in deaths due to PE in people with cancer

Analysis of US data has shown an increase in age-adjusted mortality rates due to acute pulmonary embolism in patients with cancer over the past decade.