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Pulmonary Hypertension

Free for a limited time Endocrinology Review

Highlights from EndoBridge 2023

Everything you need to know from EndoBridge 2023. Find out the latest developments across all aspects of endocrinology and metabolism, and learn about the clinical approaches to common endocrine issues.

Editor's Choice

Bacterial ventriculitis in a patient with severe periodontitis

Open Access Inflammatory Brain Disease Case Study

Poor dental health can lead to life-threatening CNS infections, even in a healthy individual. This is the first case of ventriculitis caused by an oral pathogen.

Insights into inherited valvular heart disease

Free for a limited time Congenital Valvular Heart Disease Review

What have we learned about the genetic causes of  valvular heart diseases in the last five years? This overview will bring you up to speed.

Better motor control with subcutaneous levodopa–carbidopa

17-04-2024 Parkinson's Disease News

People with Parkinson's disease gain more daily hours without dyskinesia with subcutaneous infusion of a levodopa–carbidopa solution than with oral levodopa–carbidopa.

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Live Webinar | 02-05-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on sleep in brain health

Live: Thursday 2nd May 2024, 18:00-19:30 (CEST)

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.

Dr. Rolf Fronczek
Dr. Sven Rupprecht
Dr. Renata Riha
Developed by: Springer Medicine

Case Studies

Bacterial ventriculitis in a patient with severe periodontitis

Open Access Inflammatory Brain Disease Case Study

Poor dental health can lead to life-threatening CNS infections, even in a healthy individual. This is the first case of ventriculitis caused by an oral pathogen.

A case of relapsing bronchopneumonia

Open Access Pneumonia Case Study

A patient with bronchopneumonia due to community-associated methicillin-resistant Staphylococcus aureus had an unusual course, which involved repeated relapses and needed extended antibiotic treatment.

Thyroid dysfunction due to trace element deficiency

Free for a limited time Thyroid Disease Case Study

Selenium and zinc deficiency led to thyroid dysfunction in a patient who received total parenteral nutrition without trace element supplementation for one and a half months after intestinal resection.

Live Webinar | 10-06-2024 | 16:30 (CEST)

Challenges in advanced CTCL – diagnosis and management

Live: Monday 10 June 2024, from 16:30 – 18:00 (CEST)

In this live interactive webinar, a multidisciplinary team of speakers will provide practical guidance on managing patients with cutaneous T-cell lymphoma. Learn about the key aspects of diagnosis and treatment via a series of patient cases.

Sponsored by: Kyowa Kirin

Developed by: Springer Healthcare

Current Reviews

PI3K/AKT/mTOR signaling pathway: an important driver and therapeutic target in triple-negative breast cancer

Open Access Review Article

Triple-negative breast cancer (TNBC) is a highly heterogeneous tumor lacking estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) expression. It has higher aggressiveness and metastasis than other …

Opioids-Induced Long QT Syndrome: A Challenge to Cardiac Health

Open Access Review

The challenge posed by opioid overdose has become a significant concern for health systems due to the complexities associated with drug prohibition, widespread clinical use, and potential abuse. In response, healthcare professionals have primarily …

New insights into the vitamin D/PTH axis in endocrine-driven metabolic bone diseases

Review

Bone remodeling is subject to physiological changes throughout life, resulting in modifications in skeletal composition and strength. Among the endogenous and exogenous factors regulating bone remodeling, hormones play a critical role.

Alzheimer's Disease Independent Medical Education

Advances in Alzheimer's

Alzheimer's research and care is changing rapidly. Keep up with the latest developments from key international conferences, together with expert insights on how to integrate these advances into practice.

This content is intended for healthcare professionals outside of the UK.

Supported by: Lilly

Developed by: Springer Healthcare IME

Expert Interviews | Videos (Link opens in a new window)

With adolescent obesity at an all-time high, greater understanding of the individual cost and societal burden is crucial. Discover the unique challenges faced by adolescents with obesity, and learn effective strategies to help young people to overcome this disease.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

Tweetorials | Vodcasts | Infographics (Link opens in a new window)

1.5 AMA PRA Category 1 Credit(s)

Stay up to date with the rapidly changing CGM landscape. Learn how to implement and integrate CGM into diabetes management to improve patient care and outcomes.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME
SPONSORED

Webinar

A series of patient cases underpin this live interactive webinar that aims to provide practical guidance on a multidisciplinary approach to managing patients with cutaneous T-cell lymphoma.

Sponsored by:
  • Kyowa Kirin
Developed by: Springer Healthcare

Episode 10: Disease-modifying therapy for type 1 diabetes

Reducing the burden of type 1 diabetes

Despite many recent advances in its management, type 1 diabetes remains a burden for those living with the condition.

Prof. Chantal Mathieu explains the progress being made with disease-modifying therapy for type 1 diabetes and how it has the potential to transform the current treatment landscape.

Prof. Chantal Mathieu

Further Reading

A 3D atlas of the human developing pancreas to explore progenitor proliferation and differentiation

Open Access Article

The pancreas is a vital organ involved in multiple crucial functions from glucose homeostasis to digestion [ 1 ]. It is a mixed gland composed of an exocrine and an endocrine fraction. The exocrine part contains acinar cells releasing enzymes like …

PLD2 deletion ameliorates sepsis-induced cardiomyopathy by suppressing cardiomyocyte pyroptosis via the NLRP3/caspase 1/GSDMD pathway

Open Access Original Research Paper

Despite improvements in critical care, sepsis affects more than 50 million individuals and accounts for 11 million deaths annually, making it a leading causes of death worldwide [ 1 , 2 ]. Most patients with sepsis have abnormal cardiac function …

Anterior peri-sacroiliac joint osteotomy in the treatment of malunion and nonunion of complex pelvic ring fracture: techniques and preliminary results

Open Access Original Paper

Pelvic fracture is a severe trauma which is frequently associated with chest, abdomen, haemodynamic instability, and fracture malunion and nonunion is presented once the life-threaten injury is stable [ 1 – 3 ]. A high incidence of disability and …

PI3K/AKT/mTOR signaling pathway: an important driver and therapeutic target in triple-negative breast cancer

Open Access Review Article

Triple-negative breast cancer (TNBC) is a highly heterogeneous tumor lacking estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) expression. It has higher aggressiveness and metastasis than other …