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Platelet count correlates with systemic inflammation but not with synovial vascularity in rheumatoid and psoriatic arthritis: a cross-sectional ultrasound-based study

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Abstract

This single-center study aimed to evaluate relationship between the platelets count (PLT) and the degree of synovial perfusion in patients with high disease activity of arthritis. Conducted at the Department of Early Arthritis Clinic in National Institute of Geriatrics, Rheumatology, and Rehabilitation in Warsaw, Poland. The study enrolled 60 patients diagnosed with rheumatoid arthritis (RA) and group of 20 patients with psoriasis arthritis (PsA). Different laboratory variables were assessed and particularly PLT, disease activity was assessed by DAS 28(ESR) and simplified disease activity index (SDAI). The degree of the synovial membrane vascularization was assessed using power doppler ultrasound (PDUS) and additionally vascularity index was measured by PDUS index (INDEX%) in the region of interest (ROI). Statistical analysis was performed using Prism 9.0 software package (GraphPad Software, Inc., USA). No significant correlation was observed between PLT and INDEX% synovial vascularity, which may indicate that PLT has no influence on microvascular changes in the synovium and its PDUS assessment in RA and PsA patients.
Title
Platelet count correlates with systemic inflammation but not with synovial vascularity in rheumatoid and psoriatic arthritis: a cross-sectional ultrasound-based study
Authors
Michał Jakubaszek
Brygida Kwiatkowska
Mateusz Płaza
Maria Maślińska
Publication date
01-01-2026
Publisher
Springer Berlin Heidelberg
Published in
Rheumatology International / Issue 1/2026
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-025-06047-3
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