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Open Access 10-01-2025 | Psoriatic Arthritis | Review

Unconventional Imaging Methods in Psoriatic Arthritis

Authors: Ioanna Minopoulou, Filippo Fagni, Armin Atzinger, Fredrik Albach, Georg Schett, Gerhard Krönke, Arnd Kleyer, David Simon

Published in: Current Rheumatology Reports | Issue 1/2025

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Abstract

Purpose of Review

Psoriatic arthritis (PsA) is a complex heterogeneous inflammatory disease that affects about one-third of patients with psoriasis. PsA leads to significant physical impairment and reduced quality of life. Therefore, early diagnosis and intervention are critical for improving long-term outcomes. The purpose of this review is to highlight the advantages of unconventional imaging methods in the diagnosis and management of PsA and to discuss recent advancements in imaging technology.

Recent Findings

Conventional imaging methods, such as radiography, musculoskeletal ultrasound, and magnetic resonance imaging, have been instrumental in detecting structural joint damage and inflammation. However, these imaging modalities have several limitations, resulting in their inability to detect early disease changes. Recent advancements in imaging technology have led to the development of novel imaging modalities capable of characterizing not only early structural but also molecular aspects of disease activity. These cutting-edge approaches have been lately applied to both psoriasis and PsA patients, offering new insights into disease progression, the transition from psoriasis to PsA, and treatment responses.

Summary

By providing more detailed and individualized assessments, unconventional imaging modalities may bring us closer to realizing the potential of personalized medicine in the management of PsA.
Literature
1.
go back to reference FitzGerald O, Ogdie A, Chandran V, Coates LC, Kavanaugh A, Tillett W, et al. Psoriatic arthritis. Nat Rev Dis Prim. 2021;7(1):59.PubMedCrossRef FitzGerald O, Ogdie A, Chandran V, Coates LC, Kavanaugh A, Tillett W, et al. Psoriatic arthritis. Nat Rev Dis Prim. 2021;7(1):59.PubMedCrossRef
2.
3.
go back to reference Villani AP, Rouzaud M, Sevrain M, Barnetche T, Paul C, Richard M-A, et al. Prevalence of undiagnosed psoriatic arthritis among psoriasis patients: Systematic review and meta-analysis. J Am Acad Dermatol. 2015;73(2):242–8.PubMedCrossRef Villani AP, Rouzaud M, Sevrain M, Barnetche T, Paul C, Richard M-A, et al. Prevalence of undiagnosed psoriatic arthritis among psoriasis patients: Systematic review and meta-analysis. J Am Acad Dermatol. 2015;73(2):242–8.PubMedCrossRef
4.
go back to reference Tillett W, Jadon D, Shaddick G, Cavill C, Korendowych E, de Vries CS, et al. Smoking and delay to diagnosis are associated with poorer functional outcome in psoriatic arthritis. Ann Rheum Dis. 2013;72(8):1358–61.PubMedCrossRef Tillett W, Jadon D, Shaddick G, Cavill C, Korendowych E, de Vries CS, et al. Smoking and delay to diagnosis are associated with poorer functional outcome in psoriatic arthritis. Ann Rheum Dis. 2013;72(8):1358–61.PubMedCrossRef
5.
go back to reference Haroon M, Gallagher P, FitzGerald O. Diagnostic delay of more than 6 months contributes to poor radiographic and functional outcome in psoriatic arthritis. Ann Rheum Dis. 2015;74(6):1045–50.PubMedCrossRef Haroon M, Gallagher P, FitzGerald O. Diagnostic delay of more than 6 months contributes to poor radiographic and functional outcome in psoriatic arthritis. Ann Rheum Dis. 2015;74(6):1045–50.PubMedCrossRef
6.
go back to reference Simons N, Degboé Y, Barnetche T, Cantagrel A, Ruyssen-Witrand A, Constantin A. Biological DMARD efficacy in psoriatic arthritis: a systematic literature review and meta-analysis on articular, enthesitis, dactylitis, skin and functional outcomes. Clin Exp Rheumatol. 2020;38(3):508–15.PubMed Simons N, Degboé Y, Barnetche T, Cantagrel A, Ruyssen-Witrand A, Constantin A. Biological DMARD efficacy in psoriatic arthritis: a systematic literature review and meta-analysis on articular, enthesitis, dactylitis, skin and functional outcomes. Clin Exp Rheumatol. 2020;38(3):508–15.PubMed
7.
go back to reference Tillett W, Costa L, Jadon D, Wallis D, Cavill C, McHugh J, et al. The ClASsification for psoriatic arthritis (CASPAR) criteria – a retrospective feasibility, sensitivity, and specificity study. J Rheumatol. 2012;39(1):154.PubMedCrossRef Tillett W, Costa L, Jadon D, Wallis D, Cavill C, McHugh J, et al. The ClASsification for psoriatic arthritis (CASPAR) criteria – a retrospective feasibility, sensitivity, and specificity study. J Rheumatol. 2012;39(1):154.PubMedCrossRef
8.
go back to reference Minopoulou I, Kleyer A, Yalcin-Mutlu M, Fagni F, Kemenes S, Schmidkonz C, et al. Imaging in inflammatory arthritis: progress towards precision medicine. Nat Rev Rheumatol. 2023;19(10):650–65.PubMedCrossRef Minopoulou I, Kleyer A, Yalcin-Mutlu M, Fagni F, Kemenes S, Schmidkonz C, et al. Imaging in inflammatory arthritis: progress towards precision medicine. Nat Rev Rheumatol. 2023;19(10):650–65.PubMedCrossRef
9.
go back to reference de Sousa RN, Tascilar K, Corte G, Atzinger A, Minopoulou I, Ohrndorf S, et al. Metabolic and molecular imaging in inflammatory arthritis. RMD Open. 2024;10(1):e003880.CrossRef de Sousa RN, Tascilar K, Corte G, Atzinger A, Minopoulou I, Ohrndorf S, et al. Metabolic and molecular imaging in inflammatory arthritis. RMD Open. 2024;10(1):e003880.CrossRef
10.
go back to reference Simon D, Tascilar K, Unbehend S, Bayat S, Berlin A, Liphardt AM, et al. Bone mass, bone microstructure and biomechanics in patients with hand osteoarthritis. J Bone Miner Res. 2020;35(9):1695–702.PubMedCrossRef Simon D, Tascilar K, Unbehend S, Bayat S, Berlin A, Liphardt AM, et al. Bone mass, bone microstructure and biomechanics in patients with hand osteoarthritis. J Bone Miner Res. 2020;35(9):1695–702.PubMedCrossRef
11.
go back to reference Simon D, Tascilar K, Kleyer A, Bayat S, Kampylafka E, Sokolova MV, et al. Association of structural entheseal lesions with an increased risk of progression from psoriasis to psoriatic arthritis. Arthritis Rheumatol (Hoboken, NJ). 2022;74(2):253–62.CrossRef Simon D, Tascilar K, Kleyer A, Bayat S, Kampylafka E, Sokolova MV, et al. Association of structural entheseal lesions with an increased risk of progression from psoriasis to psoriatic arthritis. Arthritis Rheumatol (Hoboken, NJ). 2022;74(2):253–62.CrossRef
12.
go back to reference Simon D, Faustini F, Kleyer A, Haschka J, Englbrecht M, Kraus S, et al. Analysis of periarticular bone changes in patients with cutaneous psoriasis without associated psoriatic arthritis. Ann Rheum Dis. 2016;75(4):660–6.PubMedCrossRef Simon D, Faustini F, Kleyer A, Haschka J, Englbrecht M, Kraus S, et al. Analysis of periarticular bone changes in patients with cutaneous psoriasis without associated psoriatic arthritis. Ann Rheum Dis. 2016;75(4):660–6.PubMedCrossRef
13.
go back to reference Simon D, Kleyer A, Bayat S, Tascilar K, Kampylafka E, Meinderink T, et al. Effect of disease-modifying anti-rheumatic drugs on bone structure and strength in psoriatic arthritis patients. Arthritis Res Ther. 2019;21(1):162.PubMedPubMedCentralCrossRef Simon D, Kleyer A, Bayat S, Tascilar K, Kampylafka E, Meinderink T, et al. Effect of disease-modifying anti-rheumatic drugs on bone structure and strength in psoriatic arthritis patients. Arthritis Res Ther. 2019;21(1):162.PubMedPubMedCentralCrossRef
14.
go back to reference Simon D, Minopoulou I, Kemenes S, Bayat S, Tascilar K, Mutlu MY, et al. Baricitinib improves bone properties and biomechanics in patients with rheumatoid arthritis: Results of the prospective interventional BARE BONE trial. Arthritis Rheumatol. 2023;75(11):1923–34.PubMedCrossRef Simon D, Minopoulou I, Kemenes S, Bayat S, Tascilar K, Mutlu MY, et al. Baricitinib improves bone properties and biomechanics in patients with rheumatoid arthritis: Results of the prospective interventional BARE BONE trial. Arthritis Rheumatol. 2023;75(11):1923–34.PubMedCrossRef
15.
go back to reference Pecherstorfer C, Simon D, Unbehend S, Ellmann H, Englbrecht M, Hartmann F, et al. A detailed analysis of the association between urate deposition and erosions and osteophytes in gout. ACR Open Rheumatol. 2020;2(10):565–72.PubMedPubMedCentralCrossRef Pecherstorfer C, Simon D, Unbehend S, Ellmann H, Englbrecht M, Hartmann F, et al. A detailed analysis of the association between urate deposition and erosions and osteophytes in gout. ACR Open Rheumatol. 2020;2(10):565–72.PubMedPubMedCentralCrossRef
16.
go back to reference Simon D, Kleyer A, Stemmler F, Simon C, Berlin A, Hueber AJ, et al. Age- and sex-dependent changes of intra-articular cortical and trabecular bone structure and the effects of rheumatoid arthritis. J Bone Miner Res : Off J Am Soc Bone Miner Res. 2017;32(4):722–30.CrossRef Simon D, Kleyer A, Stemmler F, Simon C, Berlin A, Hueber AJ, et al. Age- and sex-dependent changes of intra-articular cortical and trabecular bone structure and the effects of rheumatoid arthritis. J Bone Miner Res : Off J Am Soc Bone Miner Res. 2017;32(4):722–30.CrossRef
17.
go back to reference Kocijan R, Englbrecht M, Haschka J, Simon D, Kleyer A, Finzel S, et al. Quantitative and qualitative changes of bone in psoriasis and psoriatic arthritis patients. J Bone Miner Res. 2015;30(10):1775–83.PubMedCrossRef Kocijan R, Englbrecht M, Haschka J, Simon D, Kleyer A, Finzel S, et al. Quantitative and qualitative changes of bone in psoriasis and psoriatic arthritis patients. J Bone Miner Res. 2015;30(10):1775–83.PubMedCrossRef
18.
go back to reference Werner D, Simon D, Englbrecht M, Stemmler F, Simon C, Berlin A, et al. Early changes of the cortical micro-channel system in the bare area of the joints of patients with rheumatoid arthritis. Arthritis Rheumatol. 2017;69(8):1580–7.PubMedCrossRef Werner D, Simon D, Englbrecht M, Stemmler F, Simon C, Berlin A, et al. Early changes of the cortical micro-channel system in the bare area of the joints of patients with rheumatoid arthritis. Arthritis Rheumatol. 2017;69(8):1580–7.PubMedCrossRef
19.
go back to reference Kampylafka E, d’Oliveira I, Linz C, Lerchen V, Stemmler F, Simon D, et al. Resolution of synovitis and arrest of catabolic and anabolic bone changes in patients with psoriatic arthritis by IL-17A blockade with secukinumab: results from the prospective PSARTROS study. Arthritis Res Ther. 2018;20(1):153.PubMedPubMedCentralCrossRef Kampylafka E, d’Oliveira I, Linz C, Lerchen V, Stemmler F, Simon D, et al. Resolution of synovitis and arrest of catabolic and anabolic bone changes in patients with psoriatic arthritis by IL-17A blockade with secukinumab: results from the prospective PSARTROS study. Arthritis Res Ther. 2018;20(1):153.PubMedPubMedCentralCrossRef
20.
go back to reference Simon D, Kleyer A, Englbrecht M, Stemmler F, Simon C, Berlin A, et al. A comparative analysis of articular bone in large cohort of patients with chronic inflammatory diseases of the joints, the gut and the skin. Bone. 2018;116:87–93.PubMedCrossRef Simon D, Kleyer A, Englbrecht M, Stemmler F, Simon C, Berlin A, et al. A comparative analysis of articular bone in large cohort of patients with chronic inflammatory diseases of the joints, the gut and the skin. Bone. 2018;116:87–93.PubMedCrossRef
21.
go back to reference So H, Cheng IT, Lau S-L, Chow E, Lam T, Hung VW, et al. Effects of RANKL inhibition on promoting healing of bone erosion in rheumatoid arthritis using HR-pQCT: a 2-year, randomised, double-blind, placebo-controlled trial. Ann Rheum Dis. 2021;80(8):981.PubMedCrossRef So H, Cheng IT, Lau S-L, Chow E, Lam T, Hung VW, et al. Effects of RANKL inhibition on promoting healing of bone erosion in rheumatoid arthritis using HR-pQCT: a 2-year, randomised, double-blind, placebo-controlled trial. Ann Rheum Dis. 2021;80(8):981.PubMedCrossRef
22.
go back to reference Neumann A, Haschka J, Kleyer A, Schuster L, Englbrecht M, Berlin A, et al. Cortical bone loss is an early feature of nonradiographic axial spondyloarthritis. Arthritis Res Ther. 2018;20(1):202.PubMedPubMedCentralCrossRef Neumann A, Haschka J, Kleyer A, Schuster L, Englbrecht M, Berlin A, et al. Cortical bone loss is an early feature of nonradiographic axial spondyloarthritis. Arthritis Res Ther. 2018;20(1):202.PubMedPubMedCentralCrossRef
23.
go back to reference Simon D, Kleyer A, Faustini F, Englbrecht M, Haschka J, Berlin A, et al. Simultaneous quantification of bone erosions and enthesiophytes in the joints of patients with psoriasis or psoriatic arthritis - effects of age and disease duration. Arthritis Res Ther. 2018;20(1):203.PubMedPubMedCentralCrossRef Simon D, Kleyer A, Faustini F, Englbrecht M, Haschka J, Berlin A, et al. Simultaneous quantification of bone erosions and enthesiophytes in the joints of patients with psoriasis or psoriatic arthritis - effects of age and disease duration. Arthritis Res Ther. 2018;20(1):203.PubMedPubMedCentralCrossRef
24.
go back to reference Kampylafka E, Tascilar K, Lerchen V, Linz C, Sokolova M, Zekovic A, et al. Secukinumab leads to shifts from stage-based towards response-based disease clusters-comparative data from very early and established psoriatic arthritis. Arthritis Res Ther. 2020;22(1):207.PubMedPubMedCentralCrossRef Kampylafka E, Tascilar K, Lerchen V, Linz C, Sokolova M, Zekovic A, et al. Secukinumab leads to shifts from stage-based towards response-based disease clusters-comparative data from very early and established psoriatic arthritis. Arthritis Res Ther. 2020;22(1):207.PubMedPubMedCentralCrossRef
25.
go back to reference Kampylafka E, Simon D, d’Oliveira I, Linz C, Lerchen V, Englbrecht M, et al. Disease interception with interleukin-17 inhibition in high-risk psoriasis patients with subclinical joint inflammation-data from the prospective IVEPSA study. Arthritis Res Ther. 2019;21(1):178.PubMedPubMedCentralCrossRef Kampylafka E, Simon D, d’Oliveira I, Linz C, Lerchen V, Englbrecht M, et al. Disease interception with interleukin-17 inhibition in high-risk psoriasis patients with subclinical joint inflammation-data from the prospective IVEPSA study. Arthritis Res Ther. 2019;21(1):178.PubMedPubMedCentralCrossRef
26.
go back to reference Barnabe C, Toepfer D, Marotte H, Hauge EM, Scharmga A, Kocijan R, et al. Definition for rheumatoid arthritis erosions imaged with high resolution peripheral quantitative computed tomography and interreader reliability for detection and measurement. J Rheumatol. 2016;43(10):1935–40.PubMedCrossRef Barnabe C, Toepfer D, Marotte H, Hauge EM, Scharmga A, Kocijan R, et al. Definition for rheumatoid arthritis erosions imaged with high resolution peripheral quantitative computed tomography and interreader reliability for detection and measurement. J Rheumatol. 2016;43(10):1935–40.PubMedCrossRef
27.
go back to reference Erdmann-Keding M, Ohrndorf S, Werner SG, Glimm AM, Burmester GR, Kokolakis G, et al. Fluorescence optical imaging for the detection of potential psoriatic arthritis in comparison to musculoskeletal ultrasound. JDDG: J Dtsch Dermatologischen Ges. 2019;17(9):913–21.CrossRef Erdmann-Keding M, Ohrndorf S, Werner SG, Glimm AM, Burmester GR, Kokolakis G, et al. Fluorescence optical imaging for the detection of potential psoriatic arthritis in comparison to musculoskeletal ultrasound. JDDG: J Dtsch Dermatologischen Ges. 2019;17(9):913–21.CrossRef
28.
go back to reference Büttner J, Glimm AM, Kokolakis G, Erdmann-Keding M, Burmester GR, Hoff P. Follow-up comparison of fluorescence optical imaging with musculoskeletal ultrasound for early detection of psoriatic arthritis. Front Med. 2022;9:845545.CrossRef Büttner J, Glimm AM, Kokolakis G, Erdmann-Keding M, Burmester GR, Hoff P. Follow-up comparison of fluorescence optical imaging with musculoskeletal ultrasound for early detection of psoriatic arthritis. Front Med. 2022;9:845545.CrossRef
29.
go back to reference Koehm M, Ohrndorf S, Foldenauer AC, Rossmanith T, Backhaus M, Werner SG, et al. Fluorescence-optical imaging as a promising easy-to-use imaging biomarker to increase early psoriatic arthritis detection in patients with psoriasis: a cross-sectional cohort study with follow-up. RMD Open. 2022;8(2):e002682.PubMedPubMedCentralCrossRef Koehm M, Ohrndorf S, Foldenauer AC, Rossmanith T, Backhaus M, Werner SG, et al. Fluorescence-optical imaging as a promising easy-to-use imaging biomarker to increase early psoriatic arthritis detection in patients with psoriasis: a cross-sectional cohort study with follow-up. RMD Open. 2022;8(2):e002682.PubMedPubMedCentralCrossRef
30.
go back to reference Werner SG, Langer HE, Ohrndorf S, Bahner M, Schott P, Schwenke C, et al. Inflammation assessment in patients with arthritis using a novel in vivo fluorescence optical imaging technology. Ann Rheum Dis. 2012;71(4):504–10.PubMedCrossRef Werner SG, Langer HE, Ohrndorf S, Bahner M, Schott P, Schwenke C, et al. Inflammation assessment in patients with arthritis using a novel in vivo fluorescence optical imaging technology. Ann Rheum Dis. 2012;71(4):504–10.PubMedCrossRef
31.
go back to reference Schäfer VS, Hartung W, Ehrenstein B, Hoffstetter P, Müller M, Fleck M. A novel arthritis in vivo fluorescence optical imaging technology pushed to the limits. Rheumatology. 2012;52(6):1144–5.PubMedCrossRef Schäfer VS, Hartung W, Ehrenstein B, Hoffstetter P, Müller M, Fleck M. A novel arthritis in vivo fluorescence optical imaging technology pushed to the limits. Rheumatology. 2012;52(6):1144–5.PubMedCrossRef
32.
go back to reference Chaudhari AJ, Ferrero A, Godinez F, Yang K, Shelton DK, Hunter JC, et al. High-resolution (18)F-FDG PET/CT for assessing disease activity in rheumatoid and psoriatic arthritis: findings of a prospective pilot study. Br J Radiol. 2016;89(1063):20160138.PubMedPubMedCentralCrossRef Chaudhari AJ, Ferrero A, Godinez F, Yang K, Shelton DK, Hunter JC, et al. High-resolution (18)F-FDG PET/CT for assessing disease activity in rheumatoid and psoriatic arthritis: findings of a prospective pilot study. Br J Radiol. 2016;89(1063):20160138.PubMedPubMedCentralCrossRef
33.
go back to reference Takata T, Taniguchi Y, Ohnishi T, Kohsaki S, Nogami M, Nakajima H, et al. (18)FDG PET/CT is a powerful tool for detecting subclinical arthritis in patients with psoriatic arthritis and/or psoriasis vulgaris. J Dermatol Sci. 2011;64(2):144–7.PubMedCrossRef Takata T, Taniguchi Y, Ohnishi T, Kohsaki S, Nogami M, Nakajima H, et al. (18)FDG PET/CT is a powerful tool for detecting subclinical arthritis in patients with psoriatic arthritis and/or psoriasis vulgaris. J Dermatol Sci. 2011;64(2):144–7.PubMedCrossRef
34.
35.
go back to reference Rodríguez-Fonseca OD, Aguiar P, García FMG, Llana BF, Díaz CV, Grande MLD, et al. (18)F-FDG positron emission tomography as a marker of disease activity and treatment response in ankylosing spondylitis and psoriatic arthritis. Sci Rep. 2024;14(1):19907.PubMedPubMedCentralCrossRef Rodríguez-Fonseca OD, Aguiar P, García FMG, Llana BF, Díaz CV, Grande MLD, et al. (18)F-FDG positron emission tomography as a marker of disease activity and treatment response in ankylosing spondylitis and psoriatic arthritis. Sci Rep. 2024;14(1):19907.PubMedPubMedCentralCrossRef
36.
go back to reference Lindner T, Loktev A, Altmann A, Giesel F, Kratochwil C, Debus J, et al. Development of quinoline-based theranostic ligands for the targeting of fibroblast activation protein. J Nucl Med. 2018;59(9):1415–22.PubMedCrossRef Lindner T, Loktev A, Altmann A, Giesel F, Kratochwil C, Debus J, et al. Development of quinoline-based theranostic ligands for the targeting of fibroblast activation protein. J Nucl Med. 2018;59(9):1415–22.PubMedCrossRef
37.
go back to reference Kuwert T, Schmidkonz C, Prante O, Schett G, Ramming A. FAPI PET opens a new window to understanding immune-mediated inflammatory diseases. J Nucl Med. 2022;63(8):1136–7.PubMedCrossRef Kuwert T, Schmidkonz C, Prante O, Schett G, Ramming A. FAPI PET opens a new window to understanding immune-mediated inflammatory diseases. J Nucl Med. 2022;63(8):1136–7.PubMedCrossRef
38.
go back to reference Schmidkonz C, Atzinger A, Ramming A, Kuwert T. FAPI PET/CT immune-fibrosis imaging for new insights into rheumatologic disorders. J Nucl Med. 2023;64(11):1674–5.PubMedCrossRef Schmidkonz C, Atzinger A, Ramming A, Kuwert T. FAPI PET/CT immune-fibrosis imaging for new insights into rheumatologic disorders. J Nucl Med. 2023;64(11):1674–5.PubMedCrossRef
39.
go back to reference Corte G, Atzinger A, Temiz SA, de Sousa RN, Mutlu MY, Schoenau V, et al. Anatomical pattern of entheseal and synovial fibroblast activation in patients with psoriasis and its risk of developing psoriatic arthritis. RMD Open. 2024;10(2):e004294.PubMedPubMedCentralCrossRef Corte G, Atzinger A, Temiz SA, de Sousa RN, Mutlu MY, Schoenau V, et al. Anatomical pattern of entheseal and synovial fibroblast activation in patients with psoriasis and its risk of developing psoriatic arthritis. RMD Open. 2024;10(2):e004294.PubMedPubMedCentralCrossRef
40.
go back to reference Hallasch S, Giese N, Stoffels I, Klode J, Sondermann W. Multispectral optoacoustic tomography might be a helpful tool for noninvasive early diagnosis of psoriatic arthritis. Photoacoustics. 2021;21:100225.PubMedCrossRef Hallasch S, Giese N, Stoffels I, Klode J, Sondermann W. Multispectral optoacoustic tomography might be a helpful tool for noninvasive early diagnosis of psoriatic arthritis. Photoacoustics. 2021;21:100225.PubMedCrossRef
41.
go back to reference Tascilar K, Fagni F, Kleyer A, Bayat S, Heidemann R, Steiger F, et al. Non-invasive metabolic profiling of inflammation in joints and entheses by multispectral optoacoustic tomography. Rheumatology (Oxford). 2023;62(2):841–9.PubMedCrossRef Tascilar K, Fagni F, Kleyer A, Bayat S, Heidemann R, Steiger F, et al. Non-invasive metabolic profiling of inflammation in joints and entheses by multispectral optoacoustic tomography. Rheumatology (Oxford). 2023;62(2):841–9.PubMedCrossRef
42.
go back to reference Fagni F, Tascilar K, de Sousa RN, Bayat S, Sollfrank L, Kleyer A, et al. Unveiling metabolic similarities of entheses in patients with psoriasis and psoriatic arthritis using noninvasive in vivo molecular imaging: Results from a cross-sectional exploratory study. Arthritis Rheumatol. 2024;76(9):1387–96.PubMedCrossRef Fagni F, Tascilar K, de Sousa RN, Bayat S, Sollfrank L, Kleyer A, et al. Unveiling metabolic similarities of entheses in patients with psoriasis and psoriatic arthritis using noninvasive in vivo molecular imaging: Results from a cross-sectional exploratory study. Arthritis Rheumatol. 2024;76(9):1387–96.PubMedCrossRef
43.
go back to reference Folle L, Bayat S, Kleyer A, Fagni F, Kapsner LA, Schlereth M, et al. Advanced neural networks for classification of MRI in psoriatic arthritis, seronegative, and seropositive rheumatoid arthritis. Rheumatology (Oxford). 2022;61(12):4945–51.PubMedCrossRef Folle L, Bayat S, Kleyer A, Fagni F, Kapsner LA, Schlereth M, et al. Advanced neural networks for classification of MRI in psoriatic arthritis, seronegative, and seropositive rheumatoid arthritis. Rheumatology (Oxford). 2022;61(12):4945–51.PubMedCrossRef
44.
go back to reference Folle L, Simon D, Tascilar K, Krönke G, Liphardt AM, Maier A, et al. Deep learning-based classification of inflammatory arthritis by identification of joint shape patterns-how neural networks can tell us where to “Deep Dive” clinically. Front Med (Lausanne). 2022;9:850552.PubMedCrossRef Folle L, Simon D, Tascilar K, Krönke G, Liphardt AM, Maier A, et al. Deep learning-based classification of inflammatory arthritis by identification of joint shape patterns-how neural networks can tell us where to “Deep Dive” clinically. Front Med (Lausanne). 2022;9:850552.PubMedCrossRef
45.
go back to reference Folle L, Fenzl P, Fagni F, Thies M, Christlein V, Meder C, et al. DeepNAPSI multi-reader nail psoriasis prediction using deep learning. Sci Rep. 2023;13(1):5329.PubMedPubMedCentralCrossRef Folle L, Fenzl P, Fagni F, Thies M, Christlein V, Meder C, et al. DeepNAPSI multi-reader nail psoriasis prediction using deep learning. Sci Rep. 2023;13(1):5329.PubMedPubMedCentralCrossRef
46.
go back to reference Schlereth M, Mutlu MY, Utz J, Bayat S, Heimann T, Qiu J, et al. Deep learning-based classification of erosion, synovitis and osteitis in hand MRI of patients with inflammatory arthritis. RMD Open. 2024;10(2):e004273.PubMedPubMedCentralCrossRef Schlereth M, Mutlu MY, Utz J, Bayat S, Heimann T, Qiu J, et al. Deep learning-based classification of erosion, synovitis and osteitis in hand MRI of patients with inflammatory arthritis. RMD Open. 2024;10(2):e004273.PubMedPubMedCentralCrossRef
Metadata
Title
Unconventional Imaging Methods in Psoriatic Arthritis
Authors
Ioanna Minopoulou
Filippo Fagni
Armin Atzinger
Fredrik Albach
Georg Schett
Gerhard Krönke
Arnd Kleyer
David Simon
Publication date
10-01-2025
Publisher
Springer US
Published in
Current Rheumatology Reports / Issue 1/2025
Print ISSN: 1523-3774
Electronic ISSN: 1534-6307
DOI
https://doi.org/10.1007/s11926-024-01174-5